Regulation of pri-miRNA processing by the hnRNP-like protein AtGRP7 in Arabidopsis

Köster T, Meyer K, Weinholdt C, Smith LM, Lummer M, Speth C, Grosse I, Weigel D, Staiger D (2014)
Nucleic acids research 42(15): 9925-9936.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Köster, TinoUniBi ; Meyer, KatjaUniBi; Weinholdt, Claus; Smith, Lisa M.; Lummer, MartinaUniBi; Speth, Corinna; Grosse, Ivo; Weigel, Detlef; Staiger, DorotheeUniBi
Abstract / Bemerkung
The hnRNP-like glycine-rich RNA-binding protein AtGRP7 regulates pre-mRNA splicing in Arabidopsis. Here we used small RNA-seq to show that AtGRP7 also affects the miRNA inventory. AtGRP7 overexpression caused a significant reduction in the level of 30 miRNAs and an increase for 14 miRNAs with a minimum log2 fold change of ±0.5. Overaccumulation of several pri-miRNAs including pri-miR398b, pri-miR398c, pri-miR172b, pri-miR159a and pri-miR390 at the expense of the mature miRNAs suggested that AtGRP7 affects pri-miRNA processing. Indeed, RNA immunoprecipitation revealed that AtGRP7 interacts with these pri-miRNAs in vivo. Mutation of an arginine in the RNA recognition motif abrogated in vivo binding and the effect on miRNA and pri-miRNA levels, indicating that AtGRP7 inhibits processing of these pri-miRNAs by direct binding. In contrast, pri-miRNAs of selected miRNAs that were elevated or not changed in response to high AtGRP7 levels were not bound in vivo. Reduced accumulation of miR390, an initiator of trans-acting small interfering RNA (ta-siRNA) formation, also led to lower TAS3 ta-siRNA levels and increased mRNA expression of the target AUXIN RESPONSE FACTOR4. Furthermore, AtGRP7 affected splicing of pri-miR172b and pri-miR162a. Thus, AtGRP7 is an hnRNP-like protein with a role in processing of pri-miRNAs in addition to its role in pre-mRNA splicing.
Erscheinungsjahr
2014
Zeitschriftentitel
Nucleic acids research
Band
42
Ausgabe
15
Seite(n)
9925-9936
ISSN
0305-1048
eISSN
1362-4962
Page URI
https://pub.uni-bielefeld.de/record/2694724

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Köster T, Meyer K, Weinholdt C, et al. Regulation of pri-miRNA processing by the hnRNP-like protein AtGRP7 in Arabidopsis. Nucleic acids research. 2014;42(15):9925-9936.
Köster, T., Meyer, K., Weinholdt, C., Smith, L. M., Lummer, M., Speth, C., Grosse, I., et al. (2014). Regulation of pri-miRNA processing by the hnRNP-like protein AtGRP7 in Arabidopsis. Nucleic acids research, 42(15), 9925-9936. doi:10.1093/nar/gku716
Köster, Tino, Meyer, Katja, Weinholdt, Claus, Smith, Lisa M., Lummer, Martina, Speth, Corinna, Grosse, Ivo, Weigel, Detlef, and Staiger, Dorothee. 2014. “Regulation of pri-miRNA processing by the hnRNP-like protein AtGRP7 in Arabidopsis”. Nucleic acids research 42 (15): 9925-9936.
Köster, T., Meyer, K., Weinholdt, C., Smith, L. M., Lummer, M., Speth, C., Grosse, I., Weigel, D., and Staiger, D. (2014). Regulation of pri-miRNA processing by the hnRNP-like protein AtGRP7 in Arabidopsis. Nucleic acids research 42, 9925-9936.
Köster, T., et al., 2014. Regulation of pri-miRNA processing by the hnRNP-like protein AtGRP7 in Arabidopsis. Nucleic acids research, 42(15), p 9925-9936.
T. Köster, et al., “Regulation of pri-miRNA processing by the hnRNP-like protein AtGRP7 in Arabidopsis”, Nucleic acids research, vol. 42, 2014, pp. 9925-9936.
Köster, T., Meyer, K., Weinholdt, C., Smith, L.M., Lummer, M., Speth, C., Grosse, I., Weigel, D., Staiger, D.: Regulation of pri-miRNA processing by the hnRNP-like protein AtGRP7 in Arabidopsis. Nucleic acids research. 42, 9925-9936 (2014).
Köster, Tino, Meyer, Katja, Weinholdt, Claus, Smith, Lisa M., Lummer, Martina, Speth, Corinna, Grosse, Ivo, Weigel, Detlef, and Staiger, Dorothee. “Regulation of pri-miRNA processing by the hnRNP-like protein AtGRP7 in Arabidopsis”. Nucleic acids research 42.15 (2014): 9925-9936.

28 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

On the move through time - a historical review of plant clock research.
Johansson M, Köster T., Plant Biol (Stuttg) 21 Suppl 1(), 2019
PMID: 29607587
Cold-Dependent Expression and Alternative Splicing of Arabidopsis Long Non-coding RNAs.
Calixto CPG, Tzioutziou NA, James AB, Hornyik C, Guo W, Zhang R, Nimmo HG, Brown JWS., Front Plant Sci 10(), 2019
PMID: 30891054
A Role for the F-Box Protein HAWAIIAN SKIRT in Plant microRNA Function.
Lang PLM, Christie MD, Dogan ES, Schwab R, Hagmann J, van de Weyer AL, Scacchi E, Weigel D., Plant Physiol 176(1), 2018
PMID: 29114080
MAC3A and MAC3B, Two Core Subunits of the MOS4-Associated Complex, Positively Influence miRNA Biogenesis.
Li S, Liu K, Zhou B, Li M, Zhang S, Zeng L, Zhang C, Yu B., Plant Cell 30(2), 2018
PMID: 29437988
DAWDLE Interacts with DICER-LIKE Proteins to Mediate Small RNA Biogenesis.
Zhang S, Dou Y, Li S, Ren G, Chevalier D, Zhang C, Yu B., Plant Physiol 177(3), 2018
PMID: 29784765
SMA1, a homolog of the splicing factor Prp28, has a multifaceted role in miRNA biogenesis in Arabidopsis.
Li S, Xu R, Li A, Liu K, Gu L, Li M, Zhang H, Zhang Y, Zhuang S, Wang Q, Gao G, Li N, Zhang C, Li Y, Yu B., Nucleic Acids Res 46(17), 2018
PMID: 29982637
Beyond Transcription: Fine-Tuning of Circadian Timekeeping by Post-Transcriptional Regulation.
Mateos JL, de Leone MJ, Torchio J, Reichel M, Staiger D., Genes (Basel) 9(12), 2018
PMID: 30544736
Posttranscriptional coordination of splicing and miRNA biogenesis in plants.
Stepien A, Knop K, Dolata J, Taube M, Bajczyk M, Barciszewska-Pacak M, Pacak A, Jarmolowski A, Szweykowska-Kulinska Z., Wiley Interdiscip Rev RNA 8(3), 2017
PMID: 27863087
Roles of pre-mRNA splicing and polyadenylation in plant development.
Deng X, Cao X., Curr Opin Plant Biol 35(), 2017
PMID: 27866125
STV1, a ribosomal protein, binds primary microRNA transcripts to promote their interaction with the processing complex in Arabidopsis.
Li S, Liu K, Zhang S, Wang X, Rogers K, Ren G, Zhang C, Yu B., Proc Natl Acad Sci U S A 114(6), 2017
PMID: 28115696
MicroRNAs Are Intensively Regulated during Induction of Somatic Embryogenesis in Arabidopsis.
Szyrajew K, Bielewicz D, Dolata J, Wójcik AM, Nowak K, Szczygieł-Sommer A, Szweykowska-Kulinska Z, Jarmolowski A, Gaj MD., Front Plant Sci 8(), 2017
PMID: 28167951
RNA-Binding Proteins Revisited - The Emerging Arabidopsis mRNA Interactome.
Köster T, Marondedze C, Meyer K, Staiger D., Trends Plant Sci 22(6), 2017
PMID: 28412036
The SnRK2 kinases modulate miRNA accumulation in Arabidopsis.
Yan J, Wang P, Wang B, Hsu CC, Tang K, Zhang H, Hou YJ, Zhao Y, Wang Q, Zhao C, Zhu X, Tao WA, Li J, Zhu JK., PLoS Genet 13(4), 2017
PMID: 28419088
The 'how' and 'where' of plant microRNAs.
Yu Y, Jia T, Chen X., New Phytol 216(4), 2017
PMID: 29048752
Adaptation of iCLIP to plants determines the binding landscape of the clock-regulated RNA-binding protein AtGRP7.
Meyer K, Köster T, Nolte C, Weinholdt C, Lewinski M, Grosse I, Staiger D., Genome Biol 18(1), 2017
PMID: 29084609
AtGRP3 Is Implicated in Root Size and Aluminum Response Pathways in Arabidopsis.
Mangeon A, Pardal R, Menezes-Salgueiro AD, Duarte GL, de Seixas R, Cruz FP, Cardeal V, Magioli C, Ricachenevsky FK, Margis R, Sachetto-Martins G., PLoS One 11(3), 2016
PMID: 26939065
Cold-inducible proteins CIRP and RBM3, a unique couple with activities far beyond the cold.
Zhu X, Bührer C, Wellmann S., Cell Mol Life Sci 73(20), 2016
PMID: 27147467
Active 5' splice sites regulate the biogenesis efficiency of Arabidopsis microRNAs derived from intron-containing genes.
Knop K, Stepien A, Barciszewska-Pacak M, Taube M, Bielewicz D, Michalak M, Borst JW, Jarmolowski A, Szweykowska-Kulinska Z., Nucleic Acids Res (), 2016
PMID: 27907902
miRNA Biogenesis: A Dynamic Pathway.
Achkar NP, Cambiagno DA, Manavella PA., Trends Plant Sci 21(12), 2016
PMID: 27793495
HOS1 regulates Argonaute1 by promoting transcription of the microRNA gene MIR168b in Arabidopsis.
Wang B, Duan CG, Wang X, Hou YJ, Yan J, Gao C, Kim JH, Zhang H, Zhu JK., Plant J 81(6), 2015
PMID: 25619693
RNA around the clock - regulation at the RNA level in biological timing.
Nolte C, Staiger D., Front Plant Sci 6(), 2015
PMID: 25999975
Arabidopsis microRNA expression regulation in a wide range of abiotic stress responses.
Barciszewska-Pacak M, Milanowska K, Knop K, Bielewicz D, Nuc P, Plewka P, Pacak AM, Vazquez F, Karlowski W, Jarmolowski A, Szweykowska-Kulinska Z., Front Plant Sci 6(), 2015
PMID: 26089831
New insights into pri-miRNA processing and accumulation in plants.
Zhang S, Liu Y, Yu B., Wiley Interdiscip Rev RNA 6(5), 2015
PMID: 26119101

86 References

Daten bereitgestellt von Europe PubMed Central.

RNA-binding proteins and circadian rhythms in Arabidopsis thaliana.
Staiger D., Philos. Trans. R. Soc. Lond., B, Biol. Sci. 356(1415), 2001
PMID: 11710982
Regulation of flowering time by RNA processing.
Terzi LC, Simpson GG., Curr. Top. Microbiol. Immunol. 326(), 2008
PMID: 18630754
Alternative pre-mRNA splicing: the logic of combinatorial control.
Smith CW, Valcarcel J., Trends Biochem. Sci. 25(8), 2000
PMID: 10916158
Functional diversity of the hnRNPs: past, present and perspectives.
Han SP, Tang YH, Smith R., Biochem. J. 430(3), 2010
PMID: 20795951
MicroRNA networks and developmental plasticity in plants.
Rubio-Somoza I, Weigel D., Trends Plant Sci. 16(5), 2011
PMID: 21466971
Biogenesis, turnover, and mode of action of plant microRNAs.
Rogers K, Chen X., Plant Cell 25(7), 2013
PMID: 23881412
Expression of Arabidopsis MIRNA genes.
Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC., Plant Physiol. 138(4), 2005
PMID: 16040653
The FHA domain proteins DAWDLE in Arabidopsis and SNIP1 in humans act in small RNA biogenesis.
Yu B, Bi L, Zheng B, Ji L, Chevalier D, Agarwal M, Ramachandran V, Li W, Lagrange T, Walker JC, Chen X., Proc. Natl. Acad. Sci. U.S.A. 105(29), 2008
PMID: 18632581
Methylation as a crucial step in plant microRNA biogenesis.
Yu B, Yang Z, Li J, Minakhina S, Yang M, Padgett RW, Steward R, Chen X., Science 307(5711), 2005
PMID: 15705854
Widespread translational inhibition by plant miRNAs and siRNAs.
Brodersen P, Sakvarelidze-Achard L, Bruun-Rasmussen M, Dunoyer P, Yamamoto YY, Sieburth L, Voinnet O., Science 320(5880), 2008
PMID: 18483398
Specific effects of microRNAs on the plant transcriptome.
Schwab R, Palatnik JF, Riester M, Schommer C, Schmid M, Weigel D., Dev. Cell 8(4), 2005
PMID: 15809034
Sorting of small RNAs into Arabidopsis argonaute complexes is directed by the 5' terminal nucleotide.
Mi S, Cai T, Hu Y, Chen Y, Hodges E, Ni F, Wu L, Li S, Zhou H, Long C, Chen S, Hannon GJ, Qi Y., Cell 133(1), 2008
PMID: 18342361
Arabidopsis Argonaute 2 regulates innate immunity via miRNA393(∗)-mediated silencing of a Golgi-localized SNARE gene, MEMB12.
Zhang X, Zhao H, Gao S, Wang WC, Katiyar-Agarwal S, Huang HD, Raikhel N, Jin H., Mol. Cell 42(3), 2011
PMID: 21549312
Regulation of miRNA abundance by RNA binding protein TOUGH in Arabidopsis.
Ren G, Xie M, Dou Y, Zhang S, Zhang C, Yu B., Proc. Natl. Acad. Sci. U.S.A. 109(31), 2012
PMID: 22802657
Dual roles of the nuclear cap-binding complex and SERRATE in pre-mRNA splicing and microRNA processing in Arabidopsis thaliana.
Laubinger S, Sachsenberg T, Zeller G, Busch W, Lohmann JU, Ratsch G, Weigel D., Proc. Natl. Acad. Sci. U.S.A. 105(25), 2008
PMID: 18550839
Two cap-binding proteins CBP20 and CBP80 are involved in processing primary MicroRNAs.
Kim S, Yang JY, Xu J, Jang IC, Prigge MJ, Chua NH., Plant Cell Physiol. 49(11), 2008
PMID: 18829588
A link between RNA metabolism and silencing affecting Arabidopsis development.
Gregory BD, O'Malley RC, Lister R, Urich MA, Tonti-Filippini J, Chen H, Millar AH, Ecker JR., Dev. Cell 14(6), 2008
PMID: 18486559
Fast-forward genetics identifies plant CPL phosphatases as regulators of miRNA processing factor HYL1.
Manavella PA, Hagmann J, Ott F, Laubinger S, Franz M, Macek B, Weigel D., Cell 151(4), 2012
PMID: 23141542
A proteomic analysis of oligo(dT)-bound mRNP containing oxidative stress-induced Arabidopsis thaliana RNA-binding proteins ATGRP7 and ATGRP8.
Schmidt F, Marnef A, Cheung MK, Wilson I, Hancock J, Staiger D, Ladomery M., Mol. Biol. Rep. 37(2), 2009
PMID: 19672695
Glycine-rich RNA-binding protein 7 affects abiotic stress responses by regulating stomata opening and closing in Arabidopsis thaliana.
Kim JS, Jung HJ, Lee HJ, Kim KA, Goh CH, Woo Y, Oh SH, Han YS, Kang H., Plant J. 55(3), 2008
PMID: 18410480
Pseudomonas HopU1 modulates plant immune receptor levels by blocking the interaction of their mRNAs with GRP7.
Nicaise V, Joe A, Jeong BR, Korneli C, Boutrot F, Westedt I, Staiger D, Alfano JR, Zipfel C., EMBO J. 32(5), 2013
PMID: 23395902
An hnRNP-like RNA-binding protein affects alternative splicing by in vivo interaction with transcripts in Arabidopsis thaliana.
Streitner C, Koster T, Simpson CG, Shaw P, Danisman S, Brown JW, Staiger D., Nucleic Acids Res. 40(22), 2012
PMID: 23042250
AtGRP7, a nuclear RNA-binding protein as a component of a circadian-regulated negative feedback loop in Arabidopsis thaliana.
Heintzen C, Nater M, Apel K, Staiger D., Proc. Natl. Acad. Sci. U.S.A. 94(16), 1997
PMID: 9238008
Auto-regulation of the circadian slave oscillator component AtGRP7 and regulation of its targets is impaired by a single RNA recognition motif point mutation.
Schoning JC, Streitner C, Page DR, Hennig S, Uchida K, Wolf E, Furuya M, Staiger D., Plant J. 52(6), 2007
PMID: 17924945
The small glycine-rich RNA binding protein AtGRP7 promotes floral transition in Arabidopsis thaliana.
Streitner C, Danisman S, Wehrle F, Schoning JC, Alfano JR, Staiger D., Plant J. 56(2), 2008
PMID: 18573194
A glycine-rich RNA-binding protein affects gibberellin biosynthesis in Arabidopsis.
Lohr B, Streitner C, Steffen A, Lange T, Staiger D., Mol. Biol. Rep. 41(1), 2013
PMID: 24281950
A type III effector ADP-ribosylates RNA-binding proteins and quells plant immunity.
Fu ZQ, Guo M, Jeong BR, Tian F, Elthon TE, Cerny RL, Staiger D, Alfano JR., Nature 447(7142), 2007
PMID: 17450127
The Atger3 promoter confers circadian clock-regulated transcription with peak expression at the beginning of the night
Staiger D., Apel K., Trepp G.., 1999
Improved northern blot method for enhanced detection of small RNA.
Pall GS, Hamilton AJ., Nat Protoc 3(6), 2008
PMID: 18536652
Salicylic acid-dependent and -independent impact of an RNA-binding protein on plant immunity.
Hackmann C, Korneli C, Kutyniok M, Koster T, Wiedenlubbert M, Muller C, Staiger D., Plant Cell Environ. 37(3), 2013
PMID: 23961939
RACK1 scaffold proteins influence miRNA abundance in Arabidopsis.
Speth C, Willing EM, Rausch S, Schneeberger K, Laubinger S., Plant J. 76(3), 2013
PMID: 23941160
RNA-binding protein immunoprecipitation from whole-cell extracts.
Koster T, Staiger D., Methods Mol. Biol. 1062(), 2014
PMID: 24057392
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome.
Langmead B, Trapnell C, Pop M, Salzberg SL., Genome Biol. 10(3), 2009
PMID: 19261174
BEDTools: a flexible suite of utilities for comparing genomic features.
Quinlan AR, Hall IM., Bioinformatics 26(6), 2010
PMID: 20110278
Differential expression analysis for sequence count data.
Anders S, Huber W., Genome Biol. 11(10), 2010
PMID: 20979621
Reversible photoswitchable DRONPA-s monitors nucleocytoplasmic transport of an RNA-binding protein in transgenic plants.
Lummer M, Humpert F, Steuwe C, Caesar K, Schuttpelz M, Sauer M, Staiger D., Traffic 12(6), 2011
PMID: 21453442
Global transcript profiling of transgenic plants constitutively overexpressing the RNA-binding protein AtGRP7.
Streitner C, Hennig L, Korneli C, Staiger D., BMC Plant Biol. 10(), 2010
PMID: 20946635
Detection of 91 potential conserved plant microRNAs in Arabidopsis thaliana and Oryza sativa identifies important target genes.
Bonnet E, Wuyts J, Rouze P, Van de Peer Y., Proc. Natl. Acad. Sci. U.S.A. 101(31), 2004
PMID: 15272084
Regulation of copper homeostasis by micro-RNA in Arabidopsis
Yamasaki H., Abdel-Ghany S.E., Cohu C.M., Kobayashi Y., Shikanai T., Pilon M.., 2007
The microRNA-regulated SBP-Box transcription factor SPL3 is a direct upstream activator of LEAFY, FRUITFULL, and APETALA1.
Yamaguchi A, Wu MF, Yang L, Wu G, Poethig RS, Wagner D., Dev. Cell 17(2), 2009
PMID: 19686687
microRNA-directed phasing during trans-acting siRNA biogenesis in plants.
Allen E, Xie Z, Gustafson AM, Carrington JC., Cell 121(2), 2005
PMID: 15851028
Repression of flowering by the miR172 target SMZ.
Mathieu J, Yant LJ, Murdter F, Kuttner F, Schmid M., PLoS Biol. 7(7), 2009
PMID: 19582143
Prediction of plant microRNA targets.
Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP., Cell 110(4), 2002
PMID: 12202040
Evolution and functional diversification of MIRNA genes.
Cuperus JT, Fahlgren N, Carrington JC., Plant Cell 23(2), 2011
PMID: 21317375
Structurally different alleles of the ath-MIR824 microRNA precursor are maintained at high frequency in Arabidopsis thaliana.
de Meaux J, Hu JY, Tartler U, Goebel U., Proc. Natl. Acad. Sci. U.S.A. 105(26), 2008
PMID: 18579782
MicroRNA-mediated regulation of stomatal development in Arabidopsis.
Kutter C, Schob H, Stadler M, Meins F Jr, Si-Ammour A., Plant Cell 19(8), 2007
PMID: 17704216
Genetic analysis reveals functional redundancy and the major target genes of the Arabidopsis miR159 family.
Allen RS, Li J, Stahle MI, Dubroue A, Gubler F, Millar AA., Proc. Natl. Acad. Sci. U.S.A. 104(41), 2007
PMID: 17916625
Bacteria-responsive microRNAs regulate plant innate immunity by modulating plant hormone networks.
Zhang W, Gao S, Zhou X, Chellappan P, Chen Z, Zhou X, Zhang X, Fromuth N, Coutino G, Coffey M, Jin H., Plant Mol. Biol. 75(1-2), 2010
PMID: 21153682
A loop-to-base processing mechanism underlies the biogenesis of plant microRNAs miR319 and miR159.
Bologna NG, Mateos JL, Bresso EG, Palatnik JF., EMBO J. 28(23), 2009
PMID: 19816405
A role for the RNA-binding protein MOS2 in microRNA maturation in Arabidopsis.
Wu X, Shi Y, Li J, Xu L, Fang Y, Li X, Qi Y., Cell Res. 23(5), 2013
PMID: 23399598
Arabidopsis proline-rich protein important for development and abiotic stress tolerance is involved in microRNA biogenesis.
Zhan X, Wang B, Li H, Liu R, Kalia RK, Zhu JK, Chinnusamy V., Proc. Natl. Acad. Sci. U.S.A. 109(44), 2012
PMID: 23071326
A diverse and evolutionarily fluid set of microRNAs in Arabidopsis thaliana.
Rajagopalan R, Vaucheret H, Trejo J, Bartel DP., Genes Dev. 20(24), 2006
PMID: 17182867
Arabidopsis primary microRNA processing proteins HYL1 and DCL1 define a nuclear body distinct from the Cajal body.
Song L, Han MH, Lesicka J, Fedoroff N., Proc. Natl. Acad. Sci. U.S.A. 104(13), 2007
PMID: 17369351
Location of a possible miRNA processing site in SmD3/SmB nuclear bodies in Arabidopsis.
Fujioka Y, Utsumi M, Ohba Y, Watanabe Y., Plant Cell Physiol. 48(9), 2007
PMID: 17675322
Multiple RNA recognition patterns during microRNA biogenesis in plants.
Bologna NG, Schapire AL, Zhai J, Chorostecki U, Boisbouvier J, Meyers BC, Palatnik JF., Genome Res. 23(10), 2013
PMID: 23990609
Enhanced microRNA accumulation through stemloop-adjacent introns.
Schwab R, Speth C, Laubinger S, Voinnet O., EMBO Rep. 14(7), 2013
PMID: 23661080
Introns of plant pri-miRNAs enhance miRNA biogenesis.
Bielewicz D, Kalak M, Kalyna M, Windels D, Barta A, Vazquez F, Szweykowska-Kulinska Z, Jarmolowski A., EMBO Rep. 14(7), 2013
PMID: 23681439
Intronic noncoding RNAs and splicing.
Brown JW, Marshall DF, Echeverria M., Trends Plant Sci. 13(7), 2008
PMID: 18555733
Characterization of 43 non-protein-coding mRNA genes in Arabidopsis, including the MIR162a-derived transcripts.
Hirsch J, Lefort V, Vankersschaver M, Boualem A, Lucas A, Thermes C, d'Aubenton-Carafa Y, Crespi M., Plant Physiol. 140(4), 2006
PMID: 16500993
Structure function analysis of an ADP-ribosyltransferase type III effector and its RNA-binding target in plant immunity.
Jeong BR, Lin Y, Joe A, Guo M, Korneli C, Yang H, Wang P, Yu M, Cerny RL, Staiger D, Alfano JR, Xu Y., J. Biol. Chem. 286(50), 2011
PMID: 22013065
The Arabidopsis double-stranded RNA-binding protein HYL1 plays a role in microRNA-mediated gene regulation.
Han MH, Goud S, Song L, Fedoroff N., Proc. Natl. Acad. Sci. U.S.A. 101(4), 2004
PMID: 14722360
Dissecting the interactions of SERRATE with RNA and DICER-LIKE 1 in Arabidopsis microRNA precursor processing.
Iwata Y, Takahashi M, Fedoroff NV, Hamdan SM., Nucleic Acids Res. 41(19), 2013
PMID: 23921632
The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a.
Guil S, Caceres JF., Nat. Struct. Mol. Biol. 14(7), 2007
PMID: 17558416
Posttranscriptional regulation of miRNAs harboring conserved terminal loops.
Michlewski G, Guil S, Semple CA, Caceres JF., Mol. Cell 32(3), 2008
PMID: 18995836
Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis.
Michlewski G, Caceres JF., Nat. Struct. Mol. Biol. 17(8), 2010
PMID: 20639884
The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs.
Trabucchi M, Briata P, Garcia-Mayoral M, Haase AD, Filipowicz W, Ramos A, Gherzi R, Rosenfeld MG., Nature 459(7249), 2009
PMID: 19458619
The RNA-binding proteins HYL1 and SE promote accurate in vitro processing of pri-miRNA by DCL1.
Dong Z, Han MH, Fedoroff N., Proc. Natl. Acad. Sci. U.S.A. 105(29), 2008
PMID: 18632569
The SERRATE protein is involved in alternative splicing in Arabidopsis thaliana.
Raczynska KD, Stepien A, Kierzkowski D, Kalak M, Bajczyk M, McNicol J, Simpson CG, Szweykowska-Kulinska Z, Brown JW, Jarmolowski A., Nucleic Acids Res. 42(2), 2013
PMID: 24137006
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