An environmental bacterial taxon with a large and distinct metabolic repertoire
Wilson MC, Mori T, Rückert C, Uria AR, Helf MJ, Takada K, Gernert C, Steffens UAE, Heycke N, Schmitt S, Rinke C, et al. (2014)
Nature 506(7486): 58-62.
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Autor*in
Wilson, Micheal C;
Mori, Tetsushi;
Rückert, ChristianUniBi ;
Uria, Agustinus R;
Helf, Maximilian J;
Takada, Kentaro;
Gernert, Christine;
Steffens, Ursula A E;
Heycke, Nina;
Schmitt, Susanne;
Rinke, Christian;
Helfrich, Eric J N
Alle
Alle
Einrichtung
Abstract / Bemerkung
: Cultivated bacteria such as actinomycetes are a highly useful source of biomedically important natural products. However, such 'talented' producers represent only a minute fraction of the entire, mostly uncultivated, prokaryotic diversity. The uncultured majority is generally perceived as a large, untapped resource of new drug candidates, but so far it is unknown whether taxa containing talented bacteria indeed exist. Here we report the single-cell- and metagenomics-based discovery of such producers. Two phylotypes of the candidate genus 'Entotheonella' with genomes of greater than 9 megabases and multiple, distinct biosynthetic gene clusters co-inhabit the chemically and microbially rich marine sponge Theonella swinhoei. Almost all bioactive polyketides and peptides known from this animal were attributed to a single phylotype. 'Entotheonella' spp. are widely distributed in sponges and belong to an environmental taxon proposed here as candidate phylum 'Tectomicrobia'. The pronounced bioactivities and chemical uniqueness of 'Entotheonella' compounds provide significant opportunities for ecological studies and drug discovery.
Erscheinungsjahr
2014
Zeitschriftentitel
Nature
Band
506
Ausgabe
7486
Seite(n)
58-62
ISSN
0028-0836
eISSN
1476-4687
Page URI
https://pub.uni-bielefeld.de/record/2653196
Zitieren
Wilson MC, Mori T, Rückert C, et al. An environmental bacterial taxon with a large and distinct metabolic repertoire. Nature. 2014;506(7486):58-62.
Wilson, M. C., Mori, T., Rückert, C., Uria, A. R., Helf, M. J., Takada, K., Gernert, C., et al. (2014). An environmental bacterial taxon with a large and distinct metabolic repertoire. Nature, 506(7486), 58-62. doi:10.1038/nature12959
Wilson, Micheal C, Mori, Tetsushi, Rückert, Christian, Uria, Agustinus R, Helf, Maximilian J, Takada, Kentaro, Gernert, Christine, et al. 2014. “An environmental bacterial taxon with a large and distinct metabolic repertoire”. Nature 506 (7486): 58-62.
Wilson, M. C., Mori, T., Rückert, C., Uria, A. R., Helf, M. J., Takada, K., Gernert, C., Steffens, U. A. E., Heycke, N., Schmitt, S., et al. (2014). An environmental bacterial taxon with a large and distinct metabolic repertoire. Nature 506, 58-62.
Wilson, M.C., et al., 2014. An environmental bacterial taxon with a large and distinct metabolic repertoire. Nature, 506(7486), p 58-62.
M.C. Wilson, et al., “An environmental bacterial taxon with a large and distinct metabolic repertoire”, Nature, vol. 506, 2014, pp. 58-62.
Wilson, M.C., Mori, T., Rückert, C., Uria, A.R., Helf, M.J., Takada, K., Gernert, C., Steffens, U.A.E., Heycke, N., Schmitt, S., Rinke, C., Helfrich, E.J.N., Brachmann, A.O., Gurgui, C., Wakimoto, T., Kracht, M., Crüsemann, M., Hentschel, U., Abe, I., Matsunaga, S., Kalinowski, J., Takeyama, H., Piel, J.: An environmental bacterial taxon with a large and distinct metabolic repertoire. Nature. 506, 58-62 (2014).
Wilson, Micheal C, Mori, Tetsushi, Rückert, Christian, Uria, Agustinus R, Helf, Maximilian J, Takada, Kentaro, Gernert, Christine, Steffens, Ursula A E, Heycke, Nina, Schmitt, Susanne, Rinke, Christian, Helfrich, Eric J N, Brachmann, Alexander O, Gurgui, Cristian, Wakimoto, Toshiyuki, Kracht, Matthias, Crüsemann, Max, Hentschel, Ute, Abe, Ikuro, Matsunaga, Shigeki, Kalinowski, Jörn, Takeyama, Haruko, and Piel, Jörn. “An environmental bacterial taxon with a large and distinct metabolic repertoire”. Nature 506.7486 (2014): 58-62.
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UNIPROT
17418 Einträge gefunden, die diesen Artikel zitieren von denen 10 angezeigt werden
CinA-like protein (UNIPROT: W4LA76)
Organism: Candidatus Entotheonella sp. TSY2
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Organism: Candidatus Entotheonella sp. TSY2
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Aminopyrimidine aminohydrolase (UNIPROT: W4LEG3)
Organism: Candidatus Entotheonella sp. TSY2
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Organism: Candidatus Entotheonella sp. TSY2
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UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (UNIPROT: W4LU52)
Organism: Candidatus Entotheonella sp. TSY1
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Organism: Candidatus Entotheonella sp. TSY1
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NADH-quinone oxidoreductase subunit H (UNIPROT: W4LYQ0)
Organism: Candidatus Entotheonella sp. TSY1
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Organism: Candidatus Entotheonella sp. TSY1
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Phosphatidylserine decarboxylase (UNIPROT: W4LF03)
Organism: Candidatus Entotheonella sp. TSY1
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Organism: Candidatus Entotheonella sp. TSY1
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Sulfurtransferase (UNIPROT: W4LYM0)
Organism: Candidatus Entotheonella sp. TSY2
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Organism: Candidatus Entotheonella sp. TSY2
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Uncharacterized protein (UNIPROT: W4L1J1)
Organism: Candidatus Entotheonella sp. TSY1
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Organism: Candidatus Entotheonella sp. TSY1
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Uncharacterized protein (UNIPROT: W4L3G1)
Organism: Candidatus Entotheonella sp. TSY1
Download in FASTA format
Organism: Candidatus Entotheonella sp. TSY1
Download in FASTA format
Uncharacterized protein (UNIPROT: W4L3L0)
Organism: Candidatus Entotheonella sp. TSY1
Download in FASTA format
Organism: Candidatus Entotheonella sp. TSY1
Download in FASTA format
181 Zitationen in Europe PMC
Daten bereitgestellt von Europe PubMed Central.
Disruption of N-acyl-homoserine lactone-specific signalling and virulence in clinical pathogens by marine sponge bacteria.
Gutiérrez-Barranquero JA, Reen FJ, Parages ML, McCarthy R, Dobson ADW, O'Gara F., Microb Biotechnol 12(5), 2019
PMID: 29105344
Gutiérrez-Barranquero JA, Reen FJ, Parages ML, McCarthy R, Dobson ADW, O'Gara F., Microb Biotechnol 12(5), 2019
PMID: 29105344
A diversity-oriented rhodamine library for wide-spectrum bactericidal agents with low inducible resistance against resistant pathogens.
Luo X, Qian L, Xiao Y, Tang Y, Zhao Y, Wang X, Gu L, Lei Z, Bao J, Wu J, He T, Hu F, Zheng J, Li H, Zhu W, Shao L, Dong X, Chen D, Qian X, Yang Y., Nat Commun 10(1), 2019
PMID: 30651565
Luo X, Qian L, Xiao Y, Tang Y, Zhao Y, Wang X, Gu L, Lei Z, Bao J, Wu J, He T, Hu F, Zheng J, Li H, Zhu W, Shao L, Dong X, Chen D, Qian X, Yang Y., Nat Commun 10(1), 2019
PMID: 30651565
The Quest for Novel Antimicrobial Compounds: Emerging Trends in Research, Development, and Technologies.
Mantravadi PK, Kalesh KA, Dobson RCJ, Hudson AO, Parthasarathy A., Antibiotics (Basel) 8(1), 2019
PMID: 30682820
Mantravadi PK, Kalesh KA, Dobson RCJ, Hudson AO, Parthasarathy A., Antibiotics (Basel) 8(1), 2019
PMID: 30682820
Genomic blueprints of sponge-prokaryote symbiosis are shared by low abundant and cultivatable Alphaproteobacteria.
Karimi E, Keller-Costa T, Slaby BM, Cox CJ, da Rocha UN, Hentschel U, Costa R., Sci Rep 9(1), 2019
PMID: 30760820
Karimi E, Keller-Costa T, Slaby BM, Cox CJ, da Rocha UN, Hentschel U, Costa R., Sci Rep 9(1), 2019
PMID: 30760820
Comparative Genomics of Cyanobacterial Symbionts Reveals Distinct, Specialized Metabolism in Tropical Dysideidae Sponges.
Schorn MA, Jordan PA, Podell S, Blanton JM, Agarwal V, Biggs JS, Allen EE, Moore BS., MBio 10(3), 2019
PMID: 31088928
Schorn MA, Jordan PA, Podell S, Blanton JM, Agarwal V, Biggs JS, Allen EE, Moore BS., MBio 10(3), 2019
PMID: 31088928
Diaphorin, a polyketide produced by a bacterial symbiont of the Asian citrus psyllid, kills various human cancer cells.
Nakabachi A, Okamura K., PLoS One 14(6), 2019
PMID: 31181122
Nakabachi A, Okamura K., PLoS One 14(6), 2019
PMID: 31181122
Diversity of tryptophan halogenases in sponges of the genus Aplysina.
Gutleben J, Koehorst JJ, McPherson K, Pomponi S, Wijffels RH, Smidt H, Sipkema D., FEMS Microbiol Ecol 95(8), 2019
PMID: 31276591
Gutleben J, Koehorst JJ, McPherson K, Pomponi S, Wijffels RH, Smidt H, Sipkema D., FEMS Microbiol Ecol 95(8), 2019
PMID: 31276591
Protein phosphatases 1 and 2A and their naturally occurring inhibitors: current topics in smooth muscle physiology and chemical biology.
Takai A, Eto M, Hirano K, Takeya K, Wakimoto T, Watanabe M., J Physiol Sci 68(1), 2018
PMID: 28681362
Takai A, Eto M, Hirano K, Takeya K, Wakimoto T, Watanabe M., J Physiol Sci 68(1), 2018
PMID: 28681362
Strategies to diversify natural products for drug discovery.
Li G, Lou HX., Med Res Rev 38(4), 2018
PMID: 29064108
Li G, Lou HX., Med Res Rev 38(4), 2018
PMID: 29064108
Phylogeny and genomics of SAUL, an enigmatic bacterial lineage frequently associated with marine sponges.
Astudillo-García C, Slaby BM, Waite DW, Bayer K, Hentschel U, Taylor MW., Environ Microbiol 20(2), 2018
PMID: 29098761
Astudillo-García C, Slaby BM, Waite DW, Bayer K, Hentschel U, Taylor MW., Environ Microbiol 20(2), 2018
PMID: 29098761
A novel Chromatiales bacterium is a potential sulfide oxidizer in multiple orders of marine sponges.
Lavy A, Keren R, Yu K, Thomas BC, Alvarez-Cohen L, Banfield JF, Ilan M., Environ Microbiol 20(2), 2018
PMID: 29194919
Lavy A, Keren R, Yu K, Thomas BC, Alvarez-Cohen L, Banfield JF, Ilan M., Environ Microbiol 20(2), 2018
PMID: 29194919
EBI Metagenomics in 2017: enriching the analysis of microbial communities, from sequence reads to assemblies.
Mitchell AL, Scheremetjew M, Denise H, Potter S, Tarkowska A, Qureshi M, Salazar GA, Pesseat S, Boland MA, Hunter FMI, Ten Hoopen P, Alako B, Amid C, Wilkinson DJ, Curtis TP, Cochrane G, Finn RD., Nucleic Acids Res 46(d1), 2018
PMID: 29069476
Mitchell AL, Scheremetjew M, Denise H, Potter S, Tarkowska A, Qureshi M, Salazar GA, Pesseat S, Boland MA, Hunter FMI, Ten Hoopen P, Alako B, Amid C, Wilkinson DJ, Curtis TP, Cochrane G, Finn RD., Nucleic Acids Res 46(d1), 2018
PMID: 29069476
Natural products: Tapping into personalized chemistry.
Davison JR, Bewley CA., Nat Chem Biol 14(2), 2018
PMID: 29337972
Davison JR, Bewley CA., Nat Chem Biol 14(2), 2018
PMID: 29337972
The Swinholide Biosynthesis Gene Cluster from a Terrestrial Cyanobacterium, Nostoc sp. Strain UHCC 0450.
Humisto A, Jokela J, Liu L, Wahlsten M, Wang H, Permi P, Machado JP, Antunes A, Fewer DP, Sivonen K., Appl Environ Microbiol 84(3), 2018
PMID: 29150506
Humisto A, Jokela J, Liu L, Wahlsten M, Wang H, Permi P, Machado JP, Antunes A, Fewer DP, Sivonen K., Appl Environ Microbiol 84(3), 2018
PMID: 29150506
Obtaining high-quality draft genomes from uncultured microbes by cleaning and co-assembly of single-cell amplified genomes.
Kogawa M, Hosokawa M, Nishikawa Y, Mori K, Takeyama H., Sci Rep 8(1), 2018
PMID: 29391438
Kogawa M, Hosokawa M, Nishikawa Y, Mori K, Takeyama H., Sci Rep 8(1), 2018
PMID: 29391438
Peptide Epimerization Machineries Found in Microorganisms.
Ogasawara Y, Dairi T., Front Microbiol 9(), 2018
PMID: 29467749
Ogasawara Y, Dairi T., Front Microbiol 9(), 2018
PMID: 29467749
Single-bacterial genomics validates rich and varied specialized metabolism of uncultivated Entotheonella sponge symbionts.
Mori T, Cahn JKB, Wilson MC, Meoded RA, Wiebach V, Martinez AFC, Helfrich EJN, Albersmeier A, Wibberg D, Dätwyler S, Keren R, Lavy A, Rückert C, Ilan M, Kalinowski J, Matsunaga S, Takeyama H, Piel J., Proc Natl Acad Sci U S A 115(8), 2018
PMID: 29439203
Mori T, Cahn JKB, Wilson MC, Meoded RA, Wiebach V, Martinez AFC, Helfrich EJN, Albersmeier A, Wibberg D, Dätwyler S, Keren R, Lavy A, Rückert C, Ilan M, Kalinowski J, Matsunaga S, Takeyama H, Piel J., Proc Natl Acad Sci U S A 115(8), 2018
PMID: 29439203
Evolutionary stability of antibiotic protection in a defensive symbiosis.
Engl T, Kroiss J, Kai M, Nechitaylo TY, Svatoš A, Kaltenpoth M., Proc Natl Acad Sci U S A 115(9), 2018
PMID: 29444867
Engl T, Kroiss J, Kai M, Nechitaylo TY, Svatoš A, Kaltenpoth M., Proc Natl Acad Sci U S A 115(9), 2018
PMID: 29444867
Secondary metabolism in the lichen symbiosis.
Calcott MJ, Ackerley DF, Knight A, Keyzers RA, Owen JG., Chem Soc Rev 47(5), 2018
PMID: 29094129
Calcott MJ, Ackerley DF, Knight A, Keyzers RA, Owen JG., Chem Soc Rev 47(5), 2018
PMID: 29094129
Bioactive cyclic molecules and drug design.
Newman DJ., Expert Opin Drug Discov 13(5), 2018
PMID: 29513042
Newman DJ., Expert Opin Drug Discov 13(5), 2018
PMID: 29513042
The sponge holobiont in a changing ocean: from microbes to ecosystems.
Pita L, Rix L, Slaby BM, Franke A, Hentschel U., Microbiome 6(1), 2018
PMID: 29523192
Pita L, Rix L, Slaby BM, Franke A, Hentschel U., Microbiome 6(1), 2018
PMID: 29523192
Microbial and Functional Biodiversity Patterns in Sponges that Accumulate Bromopyrrole Alkaloids Suggest Horizontal Gene Transfer of Halogenase Genes.
Rua CPJ, de Oliveira LS, Froes A, Tschoeke DA, Soares AC, Leomil L, Gregoracci GB, Coutinho R, Hajdu E, Thompson CC, Berlinck RGS, Thompson FL., Microb Ecol 76(3), 2018
PMID: 29546438
Rua CPJ, de Oliveira LS, Froes A, Tschoeke DA, Soares AC, Leomil L, Gregoracci GB, Coutinho R, Hajdu E, Thompson CC, Berlinck RGS, Thompson FL., Microb Ecol 76(3), 2018
PMID: 29546438
Biocontrol Activity of Volatile-Producing Bacillus megaterium and Pseudomonas protegens Against Aspergillus and Penicillium spp. Predominant in Stored Rice Grains: Study II.
Mannaa M, Kim KD., Mycobiology 46(1), 2018
PMID: 29998033
Mannaa M, Kim KD., Mycobiology 46(1), 2018
PMID: 29998033
Synergistic activity of cosecreted natural products from amoebae-associated bacteria.
Arp J, Götze S, Mukherji R, Mattern DJ, García-Altares M, Klapper M, Brock DA, Brakhage AA, Strassmann JE, Queller DC, Bardl B, Willing K, Peschel G, Stallforth P., Proc Natl Acad Sci U S A 115(15), 2018
PMID: 29592954
Arp J, Götze S, Mukherji R, Mattern DJ, García-Altares M, Klapper M, Brock DA, Brakhage AA, Strassmann JE, Queller DC, Bardl B, Willing K, Peschel G, Stallforth P., Proc Natl Acad Sci U S A 115(15), 2018
PMID: 29592954
Parallel lives of symbionts and hosts: chemical mutualism in marine animals.
Morita M, Schmidt EW., Nat Prod Rep 35(4), 2018
PMID: 29441375
Morita M, Schmidt EW., Nat Prod Rep 35(4), 2018
PMID: 29441375
Concepts and Methods to Access Novel Antibiotics from Actinomycetes.
Hug JJ, Bader CD, Remškar M, Cirnski K, Müller R., Antibiotics (Basel) 7(2), 2018
PMID: 29789481
Hug JJ, Bader CD, Remškar M, Cirnski K, Müller R., Antibiotics (Basel) 7(2), 2018
PMID: 29789481
Metagenomic binning reveals versatile nutrient cycling and distinct adaptive features in alphaproteobacterial symbionts of marine sponges.
Karimi E, Slaby BM, Soares AR, Blom J, Hentschel U, Costa R., FEMS Microbiol Ecol 94(6), 2018
PMID: 29701776
Karimi E, Slaby BM, Soares AR, Blom J, Hentschel U, Costa R., FEMS Microbiol Ecol 94(6), 2018
PMID: 29701776
Novel soil bacteria possess diverse genes for secondary metabolite biosynthesis.
Crits-Christoph A, Diamond S, Butterfield CN, Thomas BC, Banfield JF., Nature 558(7710), 2018
PMID: 29899444
Crits-Christoph A, Diamond S, Butterfield CN, Thomas BC, Banfield JF., Nature 558(7710), 2018
PMID: 29899444
High-Throughput Screening of Biodiversity for Antibiotic Discovery.
Terekhov SS, Osterman IA, Smirnov IV., Acta Naturae 10(3), 2018
PMID: 30397523
Terekhov SS, Osterman IA, Smirnov IV., Acta Naturae 10(3), 2018
PMID: 30397523
Antibiotic discovery: combining isolation chip (iChip) technology and co-culture technique.
Lodhi AF, Zhang Y, Adil M, Deng Y., Appl Microbiol Biotechnol 102(17), 2018
PMID: 29974183
Lodhi AF, Zhang Y, Adil M, Deng Y., Appl Microbiol Biotechnol 102(17), 2018
PMID: 29974183
Bipartite interactions, antibiotic production and biosynthetic potential of the Arabidopsis leaf microbiome.
Helfrich EJN, Vogel CM, Ueoka R, Schäfer M, Ryffel F, Müller DB, Probst S, Kreuzer M, Piel J, Vorholt JA., Nat Microbiol 3(8), 2018
PMID: 30038309
Helfrich EJN, Vogel CM, Ueoka R, Schäfer M, Ryffel F, Müller DB, Probst S, Kreuzer M, Piel J, Vorholt JA., Nat Microbiol 3(8), 2018
PMID: 30038309
A Polyketide Synthase Component for Oxygen Insertion into Polyketide Backbones.
Meoded RA, Ueoka R, Helfrich EJN, Jensen K, Magnus N, Piechulla B, Piel J., Angew Chem Int Ed Engl 57(36), 2018
PMID: 29898240
Meoded RA, Ueoka R, Helfrich EJN, Jensen K, Magnus N, Piechulla B, Piel J., Angew Chem Int Ed Engl 57(36), 2018
PMID: 29898240
Expressed protein profile of a Tectomicrobium and other microbial symbionts in the marine sponge Aplysina aerophoba as evidenced by metaproteomics.
Chaib De Mares M, Jiménez DJ, Palladino G, Gutleben J, Lebrun LA, Muller EEL, Wilmes P, Sipkema D, van Elsas JD., Sci Rep 8(1), 2018
PMID: 30087358
Chaib De Mares M, Jiménez DJ, Palladino G, Gutleben J, Lebrun LA, Muller EEL, Wilmes P, Sipkema D, van Elsas JD., Sci Rep 8(1), 2018
PMID: 30087358
Marine Sponges as Chloroflexi Hot Spots: Genomic Insights and High-Resolution Visualization of an Abundant and Diverse Symbiotic Clade.
Bayer K, Jahn MT, Slaby BM, Moitinho-Silva L, Hentschel U., mSystems 3(6), 2018
PMID: 30637337
Bayer K, Jahn MT, Slaby BM, Moitinho-Silva L, Hentschel U., mSystems 3(6), 2018
PMID: 30637337
Clogging the Ubiquitin-Proteasome Machinery with Marine Natural Products: Last Decade Update.
Della Sala G, Agriesti F, Mazzoccoli C, Tataranni T, Costantino V, Piccoli C., Mar Drugs 16(12), 2018
PMID: 30486251
Della Sala G, Agriesti F, Mazzoccoli C, Tataranni T, Costantino V, Piccoli C., Mar Drugs 16(12), 2018
PMID: 30486251
Bioactive Secondary Metabolites from Octocoral-Associated Microbes-New Chances for Blue Growth.
Raimundo I, Silva SG, Costa R, Keller-Costa T., Mar Drugs 16(12), 2018
PMID: 30518125
Raimundo I, Silva SG, Costa R, Keller-Costa T., Mar Drugs 16(12), 2018
PMID: 30518125
The methanogenic redox cofactor F420 is widely synthesized by aerobic soil bacteria.
Ney B, Ahmed FH, Carere CR, Biswas A, Warden AC, Morales SE, Pandey G, Watt SJ, Oakeshott JG, Taylor MC, Stott MB, Jackson CJ, Greening C., ISME J 11(1), 2017
PMID: 27505347
Ney B, Ahmed FH, Carere CR, Biswas A, Warden AC, Morales SE, Pandey G, Watt SJ, Oakeshott JG, Taylor MC, Stott MB, Jackson CJ, Greening C., ISME J 11(1), 2017
PMID: 27505347
Marine genomics: News and views.
Ribeiro ÂM, Foote AD, Kupczok A, Frazão B, Limborg MT, Piñeiro R, Abalde S, Rocha S, da Fonseca RR., Mar Genomics 31(), 2017
PMID: 27650377
Ribeiro ÂM, Foote AD, Kupczok A, Frazão B, Limborg MT, Piñeiro R, Abalde S, Rocha S, da Fonseca RR., Mar Genomics 31(), 2017
PMID: 27650377
Seven enzymes create extraordinary molecular complexity in an uncultivated bacterium.
Freeman MF, Helf MJ, Bhushan A, Morinaka BI, Piel J., Nat Chem 9(4), 2017
PMID: 28338684
Freeman MF, Helf MJ, Bhushan A, Morinaka BI, Piel J., Nat Chem 9(4), 2017
PMID: 28338684
A novel, versatile family IV carboxylesterase exhibits high stability and activity in a broad pH spectrum.
Dukunde A, Schneider D, Lu M, Brady S, Daniel R., Biotechnol Lett 39(4), 2017
PMID: 28044227
Dukunde A, Schneider D, Lu M, Brady S, Daniel R., Biotechnol Lett 39(4), 2017
PMID: 28044227
Insights into the lifestyle of uncultured bacterial natural product factories associated with marine sponges.
Lackner G, Peters EE, Helfrich EJ, Piel J., Proc Natl Acad Sci U S A 114(3), 2017
PMID: 28049838
Lackner G, Peters EE, Helfrich EJ, Piel J., Proc Natl Acad Sci U S A 114(3), 2017
PMID: 28049838
Multiple transporters are involved in natamycin efflux in Streptomyces chattanoogensis L10.
Wang TJ, Shan YM, Li H, Dou WW, Jiang XH, Mao XM, Liu SP, Guan WJ, Li YQ., Mol Microbiol 103(4), 2017
PMID: 27874224
Wang TJ, Shan YM, Li H, Dou WW, Jiang XH, Mao XM, Liu SP, Guan WJ, Li YQ., Mol Microbiol 103(4), 2017
PMID: 27874224
Enzyme from an Uncultivated Sponge Bacterium Catalyzes S-Methylation in a Ribosomal Peptide.
Helf MJ, Jud A, Piel J., Chembiochem 18(5), 2017
PMID: 27966282
Helf MJ, Jud A, Piel J., Chembiochem 18(5), 2017
PMID: 27966282
Post-translational modification of ribosomally synthesized peptides by a radical SAM epimerase in Bacillus subtilis.
Benjdia A, Guillot A, Ruffié P, Leprince J, Berteau O., Nat Chem 9(7), 2017
PMID: 28644475
Benjdia A, Guillot A, Ruffié P, Leprince J, Berteau O., Nat Chem 9(7), 2017
PMID: 28644475
The Bengamides: A Mini-Review of Natural Sources, Analogues, Biological Properties, Biosynthetic Origins, and Future Prospects.
White KN, Tenney K, Crews P., J Nat Prod 80(3), 2017
PMID: 28185457
White KN, Tenney K, Crews P., J Nat Prod 80(3), 2017
PMID: 28185457
Sponge-associated bacteria mineralize arsenic and barium on intracellular vesicles.
Keren R, Mayzel B, Lavy A, Polishchuk I, Levy D, Fakra SC, Pokroy B, Ilan M., Nat Commun 8(), 2017
PMID: 28233852
Keren R, Mayzel B, Lavy A, Polishchuk I, Levy D, Fakra SC, Pokroy B, Ilan M., Nat Commun 8(), 2017
PMID: 28233852
SAG-QC: quality control of single amplified genome information by subtracting non-target sequences based on sequence compositions.
Maruyama T, Mori T, Yamagishi K, Takeyama H., BMC Bioinformatics 18(1), 2017
PMID: 28259144
Maruyama T, Mori T, Yamagishi K, Takeyama H., BMC Bioinformatics 18(1), 2017
PMID: 28259144
New approaches to antibiotic discovery.
Kealey C, Creaven CA, Murphy CD, Brady CB., Biotechnol Lett 39(6), 2017
PMID: 28275884
Kealey C, Creaven CA, Murphy CD, Brady CB., Biotechnol Lett 39(6), 2017
PMID: 28275884
Using natural products for drug discovery: the impact of the genomics era.
Zhang MM, Zhang MM, Qiao Y, Ang EL, Zhao H., Expert Opin Drug Discov 12(5), 2017
PMID: 28277838
Zhang MM, Zhang MM, Qiao Y, Ang EL, Zhao H., Expert Opin Drug Discov 12(5), 2017
PMID: 28277838
Phakellistatins: An Underwater Unsolved Puzzle.
Meli A, Tedesco C, Della Sala G, Schettini R, Albericio F, De Riccardis F, Izzo I., Mar Drugs 15(3), 2017
PMID: 28335479
Meli A, Tedesco C, Della Sala G, Schettini R, Albericio F, De Riccardis F, Izzo I., Mar Drugs 15(3), 2017
PMID: 28335479
Genome Reduction and Microbe-Host Interactions Drive Adaptation of a Sulfur-Oxidizing Bacterium Associated with a Cold Seep Sponge.
Tian RM, Zhang W, Cai L, Wong YH, Ding W, Qian PY., mSystems 2(2), 2017
PMID: 28345060
Tian RM, Zhang W, Cai L, Wong YH, Ding W, Qian PY., mSystems 2(2), 2017
PMID: 28345060
Integrated metabolism in sponge-microbe symbiosis revealed by genome-centered metatranscriptomics.
Moitinho-Silva L, Díez-Vives C, Batani G, Esteves AI, Jahn MT, Thomas T., ISME J 11(7), 2017
PMID: 28338677
Moitinho-Silva L, Díez-Vives C, Batani G, Esteves AI, Jahn MT, Thomas T., ISME J 11(7), 2017
PMID: 28338677
Another Look at Pyrroloiminoquinone Alkaloids-Perspectives on Their Therapeutic Potential from Known Structures and Semisynthetic Analogues.
Lin S, McCauley EP, Lorig-Roach N, Tenney K, Naphen CN, Yang AM, Johnson TA, Hernadez T, Rattan R, Valeriote FA, Crews P., Mar Drugs 15(4), 2017
PMID: 28353633
Lin S, McCauley EP, Lorig-Roach N, Tenney K, Naphen CN, Yang AM, Johnson TA, Hernadez T, Rattan R, Valeriote FA, Crews P., Mar Drugs 15(4), 2017
PMID: 28353633
Cyanobacterial ent-Sterol-Like Natural Products from a Deviated Ubiquinone Pathway.
Moosmann P, Ueoka R, Grauso L, Mangoni A, Morinaka BI, Gugger M, Piel J., Angew Chem Int Ed Engl 56(18), 2017
PMID: 28370791
Moosmann P, Ueoka R, Grauso L, Mangoni A, Morinaka BI, Gugger M, Piel J., Angew Chem Int Ed Engl 56(18), 2017
PMID: 28370791
Mining prokaryotes for antimicrobial compounds: from diversity to function.
Tracanna V, de Jong A, Medema MH, Kuipers OP., FEMS Microbiol Rev 41(3), 2017
PMID: 28402441
Tracanna V, de Jong A, Medema MH, Kuipers OP., FEMS Microbiol Rev 41(3), 2017
PMID: 28402441
Chemical ecology of antibiotic production by actinomycetes.
van der Meij A, Worsley SF, Hutchings MI, van Wezel GP., FEMS Microbiol Rev 41(3), 2017
PMID: 28521336
van der Meij A, Worsley SF, Hutchings MI, van Wezel GP., FEMS Microbiol Rev 41(3), 2017
PMID: 28521336
Predicting the HMA-LMA Status in Marine Sponges by Machine Learning.
Moitinho-Silva L, Steinert G, Nielsen S, Hardoim CCP, Wu YC, McCormack GP, López-Legentil S, Marchant R, Webster N, Thomas T, Hentschel U., Front Microbiol 8(), 2017
PMID: 28533766
Moitinho-Silva L, Steinert G, Nielsen S, Hardoim CCP, Wu YC, McCormack GP, López-Legentil S, Marchant R, Webster N, Thomas T, Hentschel U., Front Microbiol 8(), 2017
PMID: 28533766
Bioactive Natural Products of Marine Sponges from the Genus Hyrtios.
Shady NH, El-Hossary EM, Fouad MA, Gulder TAM, Kamel MS, Abdelmohsen UR., Molecules 22(5), 2017
PMID: 28492499
Shady NH, El-Hossary EM, Fouad MA, Gulder TAM, Kamel MS, Abdelmohsen UR., Molecules 22(5), 2017
PMID: 28492499
Screening and identification of novel biologically active natural compounds.
Newman D., F1000Res 6(), 2017
PMID: 28649374
Newman D., F1000Res 6(), 2017
PMID: 28649374
Interpreting Microbial Biosynthesis in the Genomic Age: Biological and Practical Considerations.
Miller IJ, Chevrette MG, Kwan JC., Mar Drugs 15(6), 2017
PMID: 28587290
Miller IJ, Chevrette MG, Kwan JC., Mar Drugs 15(6), 2017
PMID: 28587290
Bioprospecting challenges in unusual environments.
Tanner K, Vilanova C, Porcar M., Microb Biotechnol 10(4), 2017
PMID: 28612429
Tanner K, Vilanova C, Porcar M., Microb Biotechnol 10(4), 2017
PMID: 28612429
Antimicrobial Potential of Bacteria Associated with Marine Sea Slugs from North Sulawesi, Indonesia.
Böhringer N, Fisch KM, Schillo D, Bara R, Hertzer C, Grein F, Eisenbarth JH, Kaligis F, Schneider T, Wägele H, König GM, Schäberle TF., Front Microbiol 8(), 2017
PMID: 28659904
Böhringer N, Fisch KM, Schillo D, Bara R, Hertzer C, Grein F, Eisenbarth JH, Kaligis F, Schneider T, Wägele H, König GM, Schäberle TF., Front Microbiol 8(), 2017
PMID: 28659904
Antibiotics from Gram-negative bacteria: a comprehensive overview and selected biosynthetic highlights.
Masschelein J, Jenner M, Challis GL., Nat Prod Rep 34(7), 2017
PMID: 28650032
Masschelein J, Jenner M, Challis GL., Nat Prod Rep 34(7), 2017
PMID: 28650032
Novel approaches in function-driven single-cell genomics.
Doud DFR, Woyke T., FEMS Microbiol Rev 41(4), 2017
PMID: 28591840
Doud DFR, Woyke T., FEMS Microbiol Rev 41(4), 2017
PMID: 28591840
Form Follows Function: Designer Chemistry at the 52nd Bürgenstock Conference.
Heretsch P., Angew Chem Int Ed Engl 56(31), 2017
PMID: 28675614
Heretsch P., Angew Chem Int Ed Engl 56(31), 2017
PMID: 28675614
Brackish habitat dictates cultivable Actinobacterial diversity from marine sponges.
Ellis GA, Thomas CS, Chanana S, Adnani N, Szachowicz E, Braun DR, Harper MK, Wyche TP, Bugni TS., PLoS One 12(7), 2017
PMID: 28692665
Ellis GA, Thomas CS, Chanana S, Adnani N, Szachowicz E, Braun DR, Harper MK, Wyche TP, Bugni TS., PLoS One 12(7), 2017
PMID: 28692665
Buwchitin: A Ruminal Peptide with Antimicrobial Potential against Enterococcus faecalis.
Oyama LB, Crochet JA, Edwards JE, Girdwood SE, Cookson AR, Fernandez-Fuentes N, Hilpert K, Golyshin PN, Golyshina OV, Privé F, Hess M, Mantovani HC, Creevey CJ, Huws SA., Front Chem 5(), 2017
PMID: 28748180
Oyama LB, Crochet JA, Edwards JE, Girdwood SE, Cookson AR, Fernandez-Fuentes N, Hilpert K, Golyshin PN, Golyshina OV, Privé F, Hess M, Mantovani HC, Creevey CJ, Huws SA., Front Chem 5(), 2017
PMID: 28748180
Present and Future of Culturing Bacteria.
Overmann J, Abt B, Sikorski J., Annu Rev Microbiol 71(), 2017
PMID: 28731846
Overmann J, Abt B, Sikorski J., Annu Rev Microbiol 71(), 2017
PMID: 28731846
Highlights from the 52nd EUCHEM conference on stereochemistry, Bürgenstock, Switzerland, May 2017.
Montenegro J, Phipps RJ., Chem Commun (Camb) 53(72), 2017
PMID: 28837191
Montenegro J, Phipps RJ., Chem Commun (Camb) 53(72), 2017
PMID: 28837191
Zeamide, a Glycosylinositol Phosphorylceramide with the Novel Core Arap(1β→6)Ins Motif from the Marine Sponge Svenzea zeai.
Della Sala G, Teta R, Esposito G, Pawlik JR, Mangoni A, Costantino V., Molecules 22(9), 2017
PMID: 28862696
Della Sala G, Teta R, Esposito G, Pawlik JR, Mangoni A, Costantino V., Molecules 22(9), 2017
PMID: 28862696
The sponge microbiome project.
Moitinho-Silva L, Nielsen S, Amir A, Gonzalez A, Ackermann GL, Cerrano C, Astudillo-Garcia C, Easson C, Sipkema D, Liu F, Steinert G, Kotoulas G, McCormack GP, Feng G, Bell JJ, Vicente J, Björk JR, Montoya JM, Olson JB, Reveillaud J, Steindler L, Pineda MC, Marra MV, Ilan M, Taylor MW, Polymenakou P, Erwin PM, Schupp PJ, Simister RL, Knight R, Thacker RW, Costa R, Hill RT, Lopez-Legentil S, Dailianis T, Ravasi T, Hentschel U, Li Z, Webster NS, Thomas T., Gigascience 6(10), 2017
PMID: 29020741
Moitinho-Silva L, Nielsen S, Amir A, Gonzalez A, Ackermann GL, Cerrano C, Astudillo-Garcia C, Easson C, Sipkema D, Liu F, Steinert G, Kotoulas G, McCormack GP, Feng G, Bell JJ, Vicente J, Björk JR, Montoya JM, Olson JB, Reveillaud J, Steindler L, Pineda MC, Marra MV, Ilan M, Taylor MW, Polymenakou P, Erwin PM, Schupp PJ, Simister RL, Knight R, Thacker RW, Costa R, Hill RT, Lopez-Legentil S, Dailianis T, Ravasi T, Hentschel U, Li Z, Webster NS, Thomas T., Gigascience 6(10), 2017
PMID: 29020741
The trajectory of microbial single-cell sequencing.
Woyke T, Doud DFR, Schulz F., Nat Methods 14(11), 2017
PMID: 29088131
Woyke T, Doud DFR, Schulz F., Nat Methods 14(11), 2017
PMID: 29088131
Marine microbiome as source of natural products.
de la Calle F., Microb Biotechnol 10(6), 2017
PMID: 29076296
de la Calle F., Microb Biotechnol 10(6), 2017
PMID: 29076296
Radical SAM Enzymes in the Biosynthesis of Ribosomally Synthesized and Post-translationally Modified Peptides (RiPPs).
Benjdia A, Balty C, Berteau O., Front Chem 5(), 2017
PMID: 29167789
Benjdia A, Balty C, Berteau O., Front Chem 5(), 2017
PMID: 29167789
Large-Scale Bioinformatics Analysis of Bacillus Genomes Uncovers Conserved Roles of Natural Products in Bacterial Physiology.
Grubbs KJ, Bleich RM, Santa Maria KC, Allen SE, Farag S, AgBiome Team, Shank EA, Bowers AA., mSystems 2(6), 2017
PMID: 29152584
Grubbs KJ, Bleich RM, Santa Maria KC, Allen SE, Farag S, AgBiome Team, Shank EA, Bowers AA., mSystems 2(6), 2017
PMID: 29152584
Cyclic azole-homologated peptides from Marine sponges.
Molinski TF., Org Biomol Chem 16(1), 2017
PMID: 29210421
Molinski TF., Org Biomol Chem 16(1), 2017
PMID: 29210421
Comparative Metagenomics Reveals the Distinctive Adaptive Features of the Spongia officinalis Endosymbiotic Consortium.
Karimi E, Ramos M, Gonçalves JMS, Xavier JR, Reis MP, Costa R., Front Microbiol 8(), 2017
PMID: 29312205
Karimi E, Ramos M, Gonçalves JMS, Xavier JR, Reis MP, Costa R., Front Microbiol 8(), 2017
PMID: 29312205
Metabolic profiling as a tool for prioritizing antimicrobial compounds.
Wu C, Choi YH, van Wezel GP., J Ind Microbiol Biotechnol 43(2-3), 2016
PMID: 26335567
Wu C, Choi YH, van Wezel GP., J Ind Microbiol Biotechnol 43(2-3), 2016
PMID: 26335567
Leveraging ecological theory to guide natural product discovery.
Smanski MJ, Schlatter DC, Kinkel LL., J Ind Microbiol Biotechnol 43(2-3), 2016
PMID: 26434742
Smanski MJ, Schlatter DC, Kinkel LL., J Ind Microbiol Biotechnol 43(2-3), 2016
PMID: 26434742
Lichens as natural sources of biotechnologically relevant bacteria.
Suzuki MT, Parrot D, Berg G, Grube M, Tomasi S., Appl Microbiol Biotechnol 100(2), 2016
PMID: 26549239
Suzuki MT, Parrot D, Berg G, Grube M, Tomasi S., Appl Microbiol Biotechnol 100(2), 2016
PMID: 26549239
Culture-independent discovery of natural products from soil metagenomes.
Katz M, Hover BM, Brady SF., J Ind Microbiol Biotechnol 43(2-3), 2016
PMID: 26586404
Katz M, Hover BM, Brady SF., J Ind Microbiol Biotechnol 43(2-3), 2016
PMID: 26586404
A New N-Acyl Homoserine Lactone Synthase in an Uncultured Symbiont of the Red Sea Sponge Theonella swinhoei.
Britstein M, Devescovi G, Handley KM, Malik A, Haber M, Saurav K, Teta R, Costantino V, Burgsdorf I, Gilbert JA, Sher N, Venturi V, Steindler L., Appl Environ Microbiol 82(4), 2016
PMID: 26655754
Britstein M, Devescovi G, Handley KM, Malik A, Haber M, Saurav K, Teta R, Costantino V, Burgsdorf I, Gilbert JA, Sher N, Venturi V, Steindler L., Appl Environ Microbiol 82(4), 2016
PMID: 26655754
Prospecting for new bacterial metabolites: a glossary of approaches for inducing, activating and upregulating the biosynthesis of bacterial cryptic or silent natural products.
Zarins-Tutt JS, Barberi TT, Gao H, Mearns-Spragg A, Zhang L, Newman DJ, Goss RJ., Nat Prod Rep 33(1), 2016
PMID: 26538321
Zarins-Tutt JS, Barberi TT, Gao H, Mearns-Spragg A, Zhang L, Newman DJ, Goss RJ., Nat Prod Rep 33(1), 2016
PMID: 26538321
Antibacterial drug discovery in the resistance era.
Brown ED, Wright GD., Nature 529(7586), 2016
PMID: 26791724
Brown ED, Wright GD., Nature 529(7586), 2016
PMID: 26791724
New marine natural products from sponges (Porifera) of the order Dictyoceratida (2001 to 2012); a promising source for drug discovery, exploration and future prospects.
Mehbub MF, Perkins MV, Zhang W, Franco CMM., Biotechnol Adv 34(5), 2016
PMID: 26802363
Mehbub MF, Perkins MV, Zhang W, Franco CMM., Biotechnol Adv 34(5), 2016
PMID: 26802363
Increasing the Richness of Culturable Arsenic-Tolerant Bacteria from Theonella swinhoei by Addition of Sponge Skeleton to the Growth Medium.
Keren R, Lavy A, Ilan M., Microb Ecol 71(4), 2016
PMID: 26809776
Keren R, Lavy A, Ilan M., Microb Ecol 71(4), 2016
PMID: 26809776
Goodbye to brute force in antibiotic discovery?
Kolter R, van Wezel GP., Nat Microbiol 1(), 2016
PMID: 27571977
Kolter R, van Wezel GP., Nat Microbiol 1(), 2016
PMID: 27571977
Biosynthesis of polyketides by trans-AT polyketide synthases.
Helfrich EJ, Piel J., Nat Prod Rep 33(2), 2016
PMID: 26689670
Helfrich EJ, Piel J., Nat Prod Rep 33(2), 2016
PMID: 26689670
Dual Chemical Modification of a Polytheonamide Mimic: Rational Design and Synthesis of Ion-Channel-Forming 48-mer Peptides with Potent Cytotoxicity.
Hayata A, Itoh H, Matsutaka S, Inoue M., Chemistry (), 2016
PMID: 26833801
Hayata A, Itoh H, Matsutaka S, Inoue M., Chemistry (), 2016
PMID: 26833801
Marine natural products.
Blunt JW, Copp BR, Keyzers RA, Munro MH, Prinsep MR., Nat Prod Rep 33(3), 2016
PMID: 26837534
Blunt JW, Copp BR, Keyzers RA, Munro MH, Prinsep MR., Nat Prod Rep 33(3), 2016
PMID: 26837534
Informatic analysis reveals Legionella as a source of novel natural products.
Johnston CW, Plumb J, Li X, Grinstein S, Magarvey NA., Synth Syst Biotechnol 1(2), 2016
PMID: 29062936
Johnston CW, Plumb J, Li X, Grinstein S, Magarvey NA., Synth Syst Biotechnol 1(2), 2016
PMID: 29062936
Increasing Metagenomic Resolution of Microbiome Interactions Through Functional Phylogenomics and Bacterial Sub-Communities.
Cibrián-Jaramillo A, Barona-Gómez F., Front Genet 7(), 2016
PMID: 26904093
Cibrián-Jaramillo A, Barona-Gómez F., Front Genet 7(), 2016
PMID: 26904093
Peloruside A: a lead non-taxoid-site microtubule-stabilizing agent with potential activity against cancer, neurodegeneration, and autoimmune disease.
Kanakkanthara A, Northcote PT, Miller JH., Nat Prod Rep 33(4), 2016
PMID: 26867978
Kanakkanthara A, Northcote PT, Miller JH., Nat Prod Rep 33(4), 2016
PMID: 26867978
Culture-independent method for identification of microbial enzyme-encoding genes by activity-based single-cell sequencing using a water-in-oil microdroplet platform.
Nakamura K, Iizuka R, Nishi S, Yoshida T, Hatada Y, Takaki Y, Iguchi A, Yoon DH, Sekiguchi T, Shoji S, Funatsu T., Sci Rep 6(), 2016
PMID: 26915788
Nakamura K, Iizuka R, Nishi S, Yoshida T, Hatada Y, Takaki Y, Iguchi A, Yoon DH, Sekiguchi T, Shoji S, Funatsu T., Sci Rep 6(), 2016
PMID: 26915788
Advanced tools in marine natural drug discovery.
Zhang G, Li J, Zhu T, Gu Q, Li D., Curr Opin Biotechnol 42(), 2016
PMID: 26954946
Zhang G, Li J, Zhu T, Gu Q, Li D., Curr Opin Biotechnol 42(), 2016
PMID: 26954946
Delta-proteobacterial SAR324 group in hydrothermal plumes on the South Mid-Atlantic Ridge.
Cao H, Dong C, Bougouffa S, Li J, Zhang W, Shao Z, Bajic VB, Qian PY., Sci Rep 6(), 2016
PMID: 26953077
Cao H, Dong C, Bougouffa S, Li J, Zhang W, Shao Z, Bajic VB, Qian PY., Sci Rep 6(), 2016
PMID: 26953077
Sample Processing Impacts the Viability and Cultivability of the Sponge Microbiome.
Esteves AI, Amer N, Nguyen M, Thomas T., Front Microbiol 7(), 2016
PMID: 27242673
Esteves AI, Amer N, Nguyen M, Thomas T., Front Microbiol 7(), 2016
PMID: 27242673
Evolving medicinal chemistry strategies in antibiotic discovery.
Pawlowski AC, Johnson JW, Wright GD., Curr Opin Biotechnol 42(), 2016
PMID: 27116217
Pawlowski AC, Johnson JW, Wright GD., Curr Opin Biotechnol 42(), 2016
PMID: 27116217
Inhabitancy of active Nitrosopumilus-like ammonia-oxidizing archaea and Nitrospira nitrite-oxidizing bacteria in the sponge Theonella swinhoei.
Feng G, Sun W, Zhang F, Karthik L, Li Z., Sci Rep 6(), 2016
PMID: 27113140
Feng G, Sun W, Zhang F, Karthik L, Li Z., Sci Rep 6(), 2016
PMID: 27113140
Bioprospecting Sponge-Associated Microbes for Antimicrobial Compounds.
Indraningrat AA, Smidt H, Sipkema D., Mar Drugs 14(5), 2016
PMID: 27144573
Indraningrat AA, Smidt H, Sipkema D., Mar Drugs 14(5), 2016
PMID: 27144573
Origin of Chemical Diversity in Prochloron-Tunicate Symbiosis.
Lin Z, Torres JP, Tianero MD, Kwan JC, Schmidt EW., Appl Environ Microbiol 82(12), 2016
PMID: 27037119
Lin Z, Torres JP, Tianero MD, Kwan JC, Schmidt EW., Appl Environ Microbiol 82(12), 2016
PMID: 27037119
Calyculin: Nature's way of making the sponge-derived cytotoxin.
Wakimoto T, Egami Y, Abe I., Nat Prod Rep 33(6), 2016
PMID: 26923942
Wakimoto T, Egami Y, Abe I., Nat Prod Rep 33(6), 2016
PMID: 26923942
The evolution of genome mining in microbes - a review.
Ziemert N, Alanjary M, Weber T., Nat Prod Rep 33(8), 2016
PMID: 27272205
Ziemert N, Alanjary M, Weber T., Nat Prod Rep 33(8), 2016
PMID: 27272205
Lanthanides: New life metals?
Chistoserdova L., World J Microbiol Biotechnol 32(8), 2016
PMID: 27357406
Chistoserdova L., World J Microbiol Biotechnol 32(8), 2016
PMID: 27357406
Dissecting Bottromycin Biosynthesis Using Comparative Untargeted Metabolomics.
Crone WJ, Vior NM, Santos-Aberturas J, Schmitz LG, Leeper FJ, Truman AW., Angew Chem Int Ed Engl 55(33), 2016
PMID: 27374993
Crone WJ, Vior NM, Santos-Aberturas J, Schmitz LG, Leeper FJ, Truman AW., Angew Chem Int Ed Engl 55(33), 2016
PMID: 27374993
Antibiotic drug discovery.
Wohlleben W, Mast Y, Stegmann E, Ziemert N., Microb Biotechnol 9(5), 2016
PMID: 27470984
Wohlleben W, Mast Y, Stegmann E, Ziemert N., Microb Biotechnol 9(5), 2016
PMID: 27470984
Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking.
Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, Crüsemann M, Boudreau PD, Esquenazi E, Sandoval-Calderón M, Kersten RD, Pace LA, Quinn RA, Duncan KR, Hsu CC, Floros DJ, Gavilan RG, Kleigrewe K, Northen T, Dutton RJ, Parrot D, Carlson EE, Aigle B, Michelsen CF, Jelsbak L, Sohlenkamp C, Pevzner P, Edlund A, McLean J, Piel J, Murphy BT, Gerwick L, Liaw CC, Yang YL, Humpf HU, Maansson M, Keyzers RA, Sims AC, Johnson AR, Sidebottom AM, Sedio BE, Klitgaard A, Larson CB, P CAB, Torres-Mendoza D, Gonzalez DJ, Silva DB, Marques LM, Demarque DP, Pociute E, O'Neill EC, Briand E, Helfrich EJN, Granatosky EA, Glukhov E, Ryffel F, Houson H, Mohimani H, Kharbush JJ, Zeng Y, Vorholt JA, Kurita KL, Charusanti P, McPhail KL, Nielsen KF, Vuong L, Elfeki M, Traxler MF, Engene N, Koyama N, Vining OB, Baric R, Silva RR, Mascuch SJ, Tomasi S, Jenkins S, Macherla V, Hoffman T, Agarwal V, Williams PG, Dai J, Neupane R, Gurr J, Rodríguez AMC, Lamsa A, Zhang C, Dorrestein K, Duggan BM, Almaliti J, Allard PM, Phapale P, Nothias LF, Alexandrov T, Litaudon M, Wolfender JL, Kyle JE, Metz TO, Peryea T, Nguyen DT, VanLeer D, Shinn P, Jadhav A, Müller R, Waters KM, Shi W, Liu X, Zhang L, Knight R, Jensen PR, Palsson BO, Pogliano K, Linington RG, Gutiérrez M, Lopes NP, Gerwick WH, Moore BS, Dorrestein PC, Bandeira N., Nat Biotechnol 34(8), 2016
PMID: 27504778
Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, Crüsemann M, Boudreau PD, Esquenazi E, Sandoval-Calderón M, Kersten RD, Pace LA, Quinn RA, Duncan KR, Hsu CC, Floros DJ, Gavilan RG, Kleigrewe K, Northen T, Dutton RJ, Parrot D, Carlson EE, Aigle B, Michelsen CF, Jelsbak L, Sohlenkamp C, Pevzner P, Edlund A, McLean J, Piel J, Murphy BT, Gerwick L, Liaw CC, Yang YL, Humpf HU, Maansson M, Keyzers RA, Sims AC, Johnson AR, Sidebottom AM, Sedio BE, Klitgaard A, Larson CB, P CAB, Torres-Mendoza D, Gonzalez DJ, Silva DB, Marques LM, Demarque DP, Pociute E, O'Neill EC, Briand E, Helfrich EJN, Granatosky EA, Glukhov E, Ryffel F, Houson H, Mohimani H, Kharbush JJ, Zeng Y, Vorholt JA, Kurita KL, Charusanti P, McPhail KL, Nielsen KF, Vuong L, Elfeki M, Traxler MF, Engene N, Koyama N, Vining OB, Baric R, Silva RR, Mascuch SJ, Tomasi S, Jenkins S, Macherla V, Hoffman T, Agarwal V, Williams PG, Dai J, Neupane R, Gurr J, Rodríguez AMC, Lamsa A, Zhang C, Dorrestein K, Duggan BM, Almaliti J, Allard PM, Phapale P, Nothias LF, Alexandrov T, Litaudon M, Wolfender JL, Kyle JE, Metz TO, Peryea T, Nguyen DT, VanLeer D, Shinn P, Jadhav A, Müller R, Waters KM, Shi W, Liu X, Zhang L, Knight R, Jensen PR, Palsson BO, Pogliano K, Linington RG, Gutiérrez M, Lopes NP, Gerwick WH, Moore BS, Dorrestein PC, Bandeira N., Nat Biotechnol 34(8), 2016
PMID: 27504778
Toward Accurate and Quantitative Comparative Metagenomics.
Nayfach S, Pollard KS., Cell 166(5), 2016
PMID: 27565341
Nayfach S, Pollard KS., Cell 166(5), 2016
PMID: 27565341
Developing Techniques for the Utilization of Planctomycetes As Producers of Bioactive Molecules.
Jeske O, Surup F, Ketteniß M, Rast P, Förster B, Jogler M, Wink J, Jogler C., Front Microbiol 7(), 2016
PMID: 27594849
Jeske O, Surup F, Ketteniß M, Rast P, Förster B, Jogler M, Wink J, Jogler C., Front Microbiol 7(), 2016
PMID: 27594849
New Genomic Insights into "Entotheonella" Symbionts in Theonella swinhoei: Mixotrophy, Anaerobic Adaptation, Resilience, and Interaction.
Liu F, Li J, Feng G, Li Z., Front Microbiol 7(), 2016
PMID: 27610106
Liu F, Li J, Feng G, Li Z., Front Microbiol 7(), 2016
PMID: 27610106
HydDB: A web tool for hydrogenase classification and analysis.
Søndergaard D, Pedersen CN, Greening C., Sci Rep 6(), 2016
PMID: 27670643
Søndergaard D, Pedersen CN, Greening C., Sci Rep 6(), 2016
PMID: 27670643
Single sample resolution of rare microbial dark matter in a marine invertebrate metagenome.
Miller IJ, Weyna TR, Fong SS, Lim-Fong GE, Kwan JC., Sci Rep 6(), 2016
PMID: 27681823
Miller IJ, Weyna TR, Fong SS, Lim-Fong GE, Kwan JC., Sci Rep 6(), 2016
PMID: 27681823
Synthetic Biology of Natural Products.
Breitling R, Takano E., Cold Spring Harb Perspect Biol 8(10), 2016
PMID: 27503995
Breitling R, Takano E., Cold Spring Harb Perspect Biol 8(10), 2016
PMID: 27503995
Metagenomic Analysis of the Sponge Discodermia Reveals the Production of the Cyanobacterial Natural Product Kasumigamide by 'Entotheonella'.
Nakashima Y, Egami Y, Kimura M, Wakimoto T, Abe I., PLoS One 11(10), 2016
PMID: 27732651
Nakashima Y, Egami Y, Kimura M, Wakimoto T, Abe I., PLoS One 11(10), 2016
PMID: 27732651
Spatial Molecular Architecture of the Microbial Community of a Peltigera Lichen.
Garg N, Zeng Y, Edlund A, Melnik AV, Sanchez LM, Mohimani H, Gurevich A, Miao V, Schiffler S, Lim YW, Luzzatto-Knaan T, Cai S, Rohwer F, Pevzner PA, Cichewicz RH, Alexandrov T, Dorrestein PC., mSystems 1(6), 2016
PMID: 28028548
Garg N, Zeng Y, Edlund A, Melnik AV, Sanchez LM, Mohimani H, Gurevich A, Miao V, Schiffler S, Lim YW, Luzzatto-Knaan T, Cai S, Rohwer F, Pevzner PA, Cichewicz RH, Alexandrov T, Dorrestein PC., mSystems 1(6), 2016
PMID: 28028548
The multicellular nature of filamentous heterocyst-forming cyanobacteria.
Herrero A, Stavans J, Flores E., FEMS Microbiol Rev 40(6), 2016
PMID: 28204529
Herrero A, Stavans J, Flores E., FEMS Microbiol Rev 40(6), 2016
PMID: 28204529
An Enrichment of CRISPR and Other Defense-Related Features in Marine Sponge-Associated Microbial Metagenomes.
Horn H, Slaby BM, Jahn MT, Bayer K, Moitinho-Silva L, Förster F, Abdelmohsen UR, Hentschel U., Front Microbiol 7(), 2016
PMID: 27877161
Horn H, Slaby BM, Jahn MT, Bayer K, Moitinho-Silva L, Förster F, Abdelmohsen UR, Hentschel U., Front Microbiol 7(), 2016
PMID: 27877161
Predominately Uncultured Microbes as Sources of Bioactive Agents.
Newman DJ., Front Microbiol 7(), 2016
PMID: 27917159
Newman DJ., Front Microbiol 7(), 2016
PMID: 27917159
Complete genome sequence of the actinomycete Actinoalloteichus hymeniacidonis type strain HPA 177T isolated from a marine sponge.
Schaffert L, Albersmeier A, Winkler A, Kalinowski J, Zotchev SB, Rückert C., Stand Genomic Sci 11(), 2016
PMID: 28031775
Schaffert L, Albersmeier A, Winkler A, Kalinowski J, Zotchev SB, Rückert C., Stand Genomic Sci 11(), 2016
PMID: 28031775
The surprisingly complex immune gene repertoire of a simple sponge, exemplified by the NLR genes: a capacity for specificity?
Degnan SM., Dev Comp Immunol 48(2), 2015
PMID: 25058852
Degnan SM., Dev Comp Immunol 48(2), 2015
PMID: 25058852
Fast and sensitive protein alignment using DIAMOND.
Buchfink B, Xie C, Huson DH., Nat Methods 12(1), 2015
PMID: 25402007
Buchfink B, Xie C, Huson DH., Nat Methods 12(1), 2015
PMID: 25402007
Diversity and bioprospecting of culturable actinomycetes from marine sediment of the Yellow Sea, China.
Xiong ZQ, Liu QX, Pan ZL, Zhao N, Feng ZX, Wang Y., Arch Microbiol 197(2), 2015
PMID: 25416124
Xiong ZQ, Liu QX, Pan ZL, Zhao N, Feng ZX, Wang Y., Arch Microbiol 197(2), 2015
PMID: 25416124
Cooperation and selfishness both occur during molecular evolution.
Penny D., Biol Direct 10(), 2015
PMID: 25486885
Penny D., Biol Direct 10(), 2015
PMID: 25486885
Function-driven single-cell genomics.
Woyke T, Jarett J., Microb Biotechnol 8(1), 2015
PMID: 25627845
Woyke T, Jarett J., Microb Biotechnol 8(1), 2015
PMID: 25627845
A new antibiotic kills pathogens without detectable resistance.
Ling LL, Schneider T, Peoples AJ, Spoering AL, Engels I, Conlon BP, Mueller A, Schäberle TF, Hughes DE, Epstein S, Jones M, Lazarides L, Steadman VA, Cohen DR, Felix CR, Fetterman KA, Millett WP, Nitti AG, Zullo AM, Chen C, Lewis K., Nature 517(7535), 2015
PMID: 25561178
Ling LL, Schneider T, Peoples AJ, Spoering AL, Engels I, Conlon BP, Mueller A, Schäberle TF, Hughes DE, Epstein S, Jones M, Lazarides L, Steadman VA, Cohen DR, Felix CR, Fetterman KA, Millett WP, Nitti AG, Zullo AM, Chen C, Lewis K., Nature 517(7535), 2015
PMID: 25561178
The re-emergence of natural products for drug discovery in the genomics era.
Harvey AL, Edrada-Ebel R, Quinn RJ., Nat Rev Drug Discov 14(2), 2015
PMID: 25614221
Harvey AL, Edrada-Ebel R, Quinn RJ., Nat Rev Drug Discov 14(2), 2015
PMID: 25614221
Analysis of bacterial xylose isomerase gene diversity using gene-targeted metagenomics.
Nurdiani D, Ito M, Maruyama T, Terahara T, Mori T, Ugawa S, Takeyama H., J Biosci Bioeng 120(2), 2015
PMID: 25656071
Nurdiani D, Ito M, Maruyama T, Terahara T, Mori T, Ugawa S, Takeyama H., J Biosci Bioeng 120(2), 2015
PMID: 25656071
Diversity of Actinobacteria Associated with the Marine Ascidian Eudistoma toealensis.
Steinert G, Taylor MW, Schupp PJ., Mar Biotechnol (NY) 17(4), 2015
PMID: 25678260
Steinert G, Taylor MW, Schupp PJ., Mar Biotechnol (NY) 17(4), 2015
PMID: 25678260
The secret to a successful relationship: lasting chemistry between ascidians and their symbiotic bacteria.
Schmidt EW., Invertebr Biol 134(1), 2015
PMID: 25937788
Schmidt EW., Invertebr Biol 134(1), 2015
PMID: 25937788
Genome mining reveals unlocked bioactive potential of marine Gram-negative bacteria.
Machado H, Sonnenschein EC, Melchiorsen J, Gram L., BMC Genomics 16(), 2015
PMID: 25879706
Machado H, Sonnenschein EC, Melchiorsen J, Gram L., BMC Genomics 16(), 2015
PMID: 25879706
The changing landscape of microbial biodiversity exploration and its implications for systematics.
Hedlund BP, Dodsworth JA, Staley JT., Syst Appl Microbiol 38(4), 2015
PMID: 25921438
Hedlund BP, Dodsworth JA, Staley JT., Syst Appl Microbiol 38(4), 2015
PMID: 25921438
Molecular networking and pattern-based genome mining improves discovery of biosynthetic gene clusters and their products from Salinispora species.
Duncan KR, Crüsemann M, Lechner A, Sarkar A, Li J, Ziemert N, Wang M, Bandeira N, Moore BS, Dorrestein PC, Jensen PR., Chem Biol 22(4), 2015
PMID: 25865308
Duncan KR, Crüsemann M, Lechner A, Sarkar A, Li J, Ziemert N, Wang M, Bandeira N, Moore BS, Dorrestein PC, Jensen PR., Chem Biol 22(4), 2015
PMID: 25865308
Hexacyclopeptides secreted by an endophytic fungus Fusarium solani N06 act as crosstalk molecules in Narcissus tazetta.
Wang WX, Kusari S, Sezgin S, Lamshöft M, Kusari P, Kayser O, Spiteller M., Appl Microbiol Biotechnol 99(18), 2015
PMID: 25958995
Wang WX, Kusari S, Sezgin S, Lamshöft M, Kusari P, Kayser O, Spiteller M., Appl Microbiol Biotechnol 99(18), 2015
PMID: 25958995
Crystal Structure of Okadaic Acid Binding Protein 2.1: A Sponge Protein Implicated in Cytotoxin Accumulation.
Ehara H, Makino M, Kodama K, Konoki K, Ito T, Sekine S, Fukuzawa S, Yokoyama S, Tachibana K., Chembiochem 16(10), 2015
PMID: 25965326
Ehara H, Makino M, Kodama K, Konoki K, Ito T, Sekine S, Fukuzawa S, Yokoyama S, Tachibana K., Chembiochem 16(10), 2015
PMID: 25965326
Emerging concepts promising new horizons for marine biodiscovery and synthetic biology.
Reen FJ, Gutiérrez-Barranquero JA, Dobson AD, Adams C, O'Gara F., Mar Drugs 13(5), 2015
PMID: 25984990
Reen FJ, Gutiérrez-Barranquero JA, Dobson AD, Adams C, O'Gara F., Mar Drugs 13(5), 2015
PMID: 25984990
Endophytic and epiphytic microbes as "sources" of bioactive agents.
Newman DJ, Cragg GM., Front Chem 3(), 2015
PMID: 26052511
Newman DJ, Cragg GM., Front Chem 3(), 2015
PMID: 26052511
13-Deoxytetrodecamycin, a new tetronate ring-containing antibiotic that is active against multidrug-resistant Staphylococcus aureus.
Gverzdys T, Hart MK, Pimentel-Elardo S, Tranmer G, Nodwell JR., J Antibiot (Tokyo) 68(11), 2015
PMID: 26014719
Gverzdys T, Hart MK, Pimentel-Elardo S, Tranmer G, Nodwell JR., J Antibiot (Tokyo) 68(11), 2015
PMID: 26014719
Isolation and Total Synthesis of Kirkamide, an Aminocyclitol from an Obligate Leaf Nodule Symbiont.
Sieber S, Carlier A, Neuburger M, Grabenweger G, Eberl L, Gademann K., Angew Chem Int Ed Engl 54(27), 2015
PMID: 26033226
Sieber S, Carlier A, Neuburger M, Grabenweger G, Eberl L, Gademann K., Angew Chem Int Ed Engl 54(27), 2015
PMID: 26033226
In Silico Analysis of the Metabolic Potential and Niche Specialization of Candidate Phylum "Latescibacteria" (WS3).
Youssef NH, Farag IF, Rinke C, Hallam SJ, Woyke T, Elshahed MS., PLoS One 10(6), 2015
PMID: 26039074
Youssef NH, Farag IF, Rinke C, Hallam SJ, Woyke T, Elshahed MS., PLoS One 10(6), 2015
PMID: 26039074
Expanding the chemical space for natural products by Aspergillus-Streptomyces co-cultivation and biotransformation.
Wu C, Zacchetti B, Ram AF, van Wezel GP, Claessen D, Hae Choi Y., Sci Rep 5(), 2015
PMID: 26040782
Wu C, Zacchetti B, Ram AF, van Wezel GP, Claessen D, Hae Choi Y., Sci Rep 5(), 2015
PMID: 26040782
Discovery of microbial natural products by activation of silent biosynthetic gene clusters.
Rutledge PJ, Challis GL., Nat Rev Microbiol 13(8), 2015
PMID: 26119570
Rutledge PJ, Challis GL., Nat Rev Microbiol 13(8), 2015
PMID: 26119570
Defensive symbioses of animals with prokaryotic and eukaryotic microorganisms.
Flórez LV, Biedermann PH, Engl T, Kaltenpoth M., Nat Prod Rep 32(7), 2015
PMID: 25891201
Flórez LV, Biedermann PH, Engl T, Kaltenpoth M., Nat Prod Rep 32(7), 2015
PMID: 25891201
Individuality, phenotypic differentiation, dormancy and 'persistence' in culturable bacterial systems: commonalities shared by environmental, laboratory, and clinical microbiology.
Kell D, Potgieter M, Pretorius E., F1000Res 4(), 2015
PMID: 26629334
Kell D, Potgieter M, Pretorius E., F1000Res 4(), 2015
PMID: 26629334
Marine Structural Biomaterials in Medical Biomimicry.
Green DW, Lee JM, Jung HS., Tissue Eng Part B Rev 21(5), 2015
PMID: 25905922
Green DW, Lee JM, Jung HS., Tissue Eng Part B Rev 21(5), 2015
PMID: 25905922
Mode of action of closthioamide: the first member of the polythioamide class of bacterial DNA gyrase inhibitors.
Chiriac AI, Kloss F, Krämer J, Vuong C, Hertweck C, Sahl HG., J Antimicrob Chemother 70(9), 2015
PMID: 26174721
Chiriac AI, Kloss F, Krämer J, Vuong C, Hertweck C, Sahl HG., J Antimicrob Chemother 70(9), 2015
PMID: 26174721
Nannocystin A: an Elongation Factor 1 Inhibitor from Myxobacteria with Differential Anti-Cancer Properties.
Krastel P, Roggo S, Schirle M, Ross NT, Perruccio F, Aspesi P, Aust T, Buntin K, Estoppey D, Liechty B, Mapa F, Memmert K, Miller H, Pan X, Riedl R, Thibaut C, Thomas J, Wagner T, Weber E, Xie X, Schmitt EK, Hoepfner D., Angew Chem Int Ed Engl 54(35), 2015
PMID: 26179970
Krastel P, Roggo S, Schirle M, Ross NT, Perruccio F, Aspesi P, Aust T, Buntin K, Estoppey D, Liechty B, Mapa F, Memmert K, Miller H, Pan X, Riedl R, Thibaut C, Thomas J, Wagner T, Weber E, Xie X, Schmitt EK, Hoepfner D., Angew Chem Int Ed Engl 54(35), 2015
PMID: 26179970
The Sound of Silence: Activating Silent Biosynthetic Gene Clusters in Marine Microorganisms.
Reen FJ, Romano S, Dobson AD, O'Gara F., Mar Drugs 13(8), 2015
PMID: 26264003
Reen FJ, Romano S, Dobson AD, O'Gara F., Mar Drugs 13(8), 2015
PMID: 26264003
Mass spectrometry tools and workflows for revealing microbial chemistry.
Luzzatto-Knaan T, Melnik AV, Dorrestein PC., Analyst 140(15), 2015
PMID: 25996313
Luzzatto-Knaan T, Melnik AV, Dorrestein PC., Analyst 140(15), 2015
PMID: 25996313
Metabolic and evolutionary origin of actin-binding polyketides from diverse organisms.
Ueoka R, Uria AR, Reiter S, Mori T, Karbaum P, Peters EE, Helfrich EJ, Morinaka BI, Gugger M, Takeyama H, Matsunaga S, Piel J., Nat Chem Biol 11(9), 2015
PMID: 26236936
Ueoka R, Uria AR, Reiter S, Mori T, Karbaum P, Peters EE, Helfrich EJ, Morinaka BI, Gugger M, Takeyama H, Matsunaga S, Piel J., Nat Chem Biol 11(9), 2015
PMID: 26236936
Electrical Retrieval of Living Microorganisms from Cryopreserved Marine Sponges Using a Potential-Controlled Electrode.
Koyama S, Nishi S, Tokuda M, Uemura M, Ishikawa Y, Seya T, Chow S, Ise Y, Hatada Y, Fujiwara Y, Tsubouchi T., Mar Biotechnol (NY) 17(5), 2015
PMID: 26242755
Koyama S, Nishi S, Tokuda M, Uemura M, Ishikawa Y, Seya T, Chow S, Ise Y, Hatada Y, Fujiwara Y, Tsubouchi T., Mar Biotechnol (NY) 17(5), 2015
PMID: 26242755
Targeted metagenomics as a tool to tap into marine natural product diversity for the discovery and production of drug candidates.
Trindade M, van Zyl LJ, Navarro-Fernández J, Abd Elrazak A., Front Microbiol 6(), 2015
PMID: 26379658
Trindade M, van Zyl LJ, Navarro-Fernández J, Abd Elrazak A., Front Microbiol 6(), 2015
PMID: 26379658
Minimum Information about a Biosynthetic Gene cluster.
Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, Garg N, Geiger C, Gomez-Escribano JP, Greule A, Hadjithomas M, Haines AS, Helfrich EJ, Hillwig ML, Ishida K, Jones AC, Jones CS, Jungmann K, Kegler C, Kim HU, Kötter P, Krug D, Masschelein J, Melnik AV, Mantovani SM, Monroe EA, Moore M, Moss N, Nützmann HW, Pan G, Pati A, Petras D, Reen FJ, Rosconi F, Rui Z, Tian Z, Tobias NJ, Tsunematsu Y, Wiemann P, Wyckoff E, Yan X, Yim G, Yu F, Xie Y, Aigle B, Apel AK, Balibar CJ, Balskus EP, Barona-Gómez F, Bechthold A, Bode HB, Borriss R, Brady SF, Brakhage AA, Caffrey P, Cheng YQ, Clardy J, Cox RJ, De Mot R, Donadio S, Donia MS, van der Donk WA, Dorrestein PC, Doyle S, Driessen AJ, Ehling-Schulz M, Entian KD, Fischbach MA, Gerwick L, Gerwick WH, Gross H, Gust B, Hertweck C, Höfte M, Jensen SE, Ju J, Katz L, Kaysser L, Klassen JL, Keller NP, Kormanec J, Kuipers OP, Kuzuyama T, Kyrpides NC, Kwon HJ, Lautru S, Lavigne R, Lee CY, Linquan B, Liu X, Liu W, Luzhetskyy A, Mahmud T, Mast Y, Méndez C, Metsä-Ketelä M, Micklefield J, Mitchell DA, Moore BS, Moreira LM, Müller R, Neilan BA, Nett M, Nielsen J, O'Gara F, Oikawa H, Osbourn A, Osburne MS, Ostash B, Payne SM, Pernodet JL, Petricek M, Piel J, Ploux O, Raaijmakers JM, Salas JA, Schmitt EK, Scott B, Seipke RF, Shen B, Sherman DH, Sivonen K, Smanski MJ, Sosio M, Stegmann E, Süssmuth RD, Tahlan K, Thomas CM, Tang Y, Truman AW, Viaud M, Walton JD, Walsh CT, Weber T, van Wezel GP, Wilkinson B, Willey JM, Wohlleben W, Wright GD, Ziemert N, Zhang C, Zotchev SB, Breitling R, Takano E, Glöckner FO., Nat Chem Biol 11(9), 2015
PMID: 26284661
Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, Garg N, Geiger C, Gomez-Escribano JP, Greule A, Hadjithomas M, Haines AS, Helfrich EJ, Hillwig ML, Ishida K, Jones AC, Jones CS, Jungmann K, Kegler C, Kim HU, Kötter P, Krug D, Masschelein J, Melnik AV, Mantovani SM, Monroe EA, Moore M, Moss N, Nützmann HW, Pan G, Pati A, Petras D, Reen FJ, Rosconi F, Rui Z, Tian Z, Tobias NJ, Tsunematsu Y, Wiemann P, Wyckoff E, Yan X, Yim G, Yu F, Xie Y, Aigle B, Apel AK, Balibar CJ, Balskus EP, Barona-Gómez F, Bechthold A, Bode HB, Borriss R, Brady SF, Brakhage AA, Caffrey P, Cheng YQ, Clardy J, Cox RJ, De Mot R, Donadio S, Donia MS, van der Donk WA, Dorrestein PC, Doyle S, Driessen AJ, Ehling-Schulz M, Entian KD, Fischbach MA, Gerwick L, Gerwick WH, Gross H, Gust B, Hertweck C, Höfte M, Jensen SE, Ju J, Katz L, Kaysser L, Klassen JL, Keller NP, Kormanec J, Kuipers OP, Kuzuyama T, Kyrpides NC, Kwon HJ, Lautru S, Lavigne R, Lee CY, Linquan B, Liu X, Liu W, Luzhetskyy A, Mahmud T, Mast Y, Méndez C, Metsä-Ketelä M, Micklefield J, Mitchell DA, Moore BS, Moreira LM, Müller R, Neilan BA, Nett M, Nielsen J, O'Gara F, Oikawa H, Osbourn A, Osburne MS, Ostash B, Payne SM, Pernodet JL, Petricek M, Piel J, Ploux O, Raaijmakers JM, Salas JA, Schmitt EK, Scott B, Seipke RF, Shen B, Sherman DH, Sivonen K, Smanski MJ, Sosio M, Stegmann E, Süssmuth RD, Tahlan K, Thomas CM, Tang Y, Truman AW, Viaud M, Walton JD, Walsh CT, Weber T, van Wezel GP, Wilkinson B, Willey JM, Wohlleben W, Wright GD, Ziemert N, Zhang C, Zotchev SB, Breitling R, Takano E, Glöckner FO., Nat Chem Biol 11(9), 2015
PMID: 26284661
Computational approaches to natural product discovery.
Medema MH, Fischbach MA., Nat Chem Biol 11(9), 2015
PMID: 26284671
Medema MH, Fischbach MA., Nat Chem Biol 11(9), 2015
PMID: 26284671
Monodisperse Picoliter Droplets for Low-Bias and Contamination-Free Reactions in Single-Cell Whole Genome Amplification.
Nishikawa Y, Hosokawa M, Maruyama T, Yamagishi K, Mori T, Takeyama H., PLoS One 10(9), 2015
PMID: 26389587
Nishikawa Y, Hosokawa M, Maruyama T, Yamagishi K, Mori T, Takeyama H., PLoS One 10(9), 2015
PMID: 26389587
Investigation of Interspecies Interactions within Marine Micromonosporaceae Using an Improved Co-Culture Approach.
Adnani N, Vazquez-Rivera E, Adibhatla SN, Ellis GA, Braun DR, Bugni TS., Mar Drugs 13(10), 2015
PMID: 26404321
Adnani N, Vazquez-Rivera E, Adibhatla SN, Ellis GA, Braun DR, Bugni TS., Mar Drugs 13(10), 2015
PMID: 26404321
A new benzofuran glycoside and indole alkaloids from a sponge-associated rare actinomycete, Amycolatopsis sp.
Kwon Y, Kim SH, Shin Y, Bae M, Kim BY, Lee SK, Oh KB, Shin J, Oh DC., Mar Drugs 12(4), 2014
PMID: 24759001
Kwon Y, Kim SH, Shin Y, Bae M, Kim BY, Lee SK, Oh KB, Shin J, Oh DC., Mar Drugs 12(4), 2014
PMID: 24759001
Recent advances in genome-based polyketide discovery.
Helfrich EJ, Reiter S, Piel J., Curr Opin Biotechnol 29(), 2014
PMID: 24762576
Helfrich EJ, Reiter S, Piel J., Curr Opin Biotechnol 29(), 2014
PMID: 24762576
Proteomics meets blue biotechnology: a wealth of novelties and opportunities.
Hartmann EM, Durighello E, Pible O, Nogales B, Beltrametti F, Bosch R, Christie-Oleza JA, Armengaud J., Mar Genomics 17(), 2014
PMID: 24780860
Hartmann EM, Durighello E, Pible O, Nogales B, Beltrametti F, Bosch R, Christie-Oleza JA, Armengaud J., Mar Genomics 17(), 2014
PMID: 24780860
In situ detection of antibiotic amphotericin B produced in Streptomyces nodosus using Raman microspectroscopy.
Miyaoka R, Hosokawa M, Ando M, Mori T, Hamaguchi HO, Takeyama H., Mar Drugs 12(5), 2014
PMID: 24828290
Miyaoka R, Hosokawa M, Ando M, Mori T, Hamaguchi HO, Takeyama H., Mar Drugs 12(5), 2014
PMID: 24828290
Discovery of clostrubin, an exceptional polyphenolic polyketide antibiotic from a strictly anaerobic bacterium.
Pidot S, Ishida K, Cyrulies M, Hertweck C., Angew Chem Int Ed Engl 53(30), 2014
PMID: 24827417
Pidot S, Ishida K, Cyrulies M, Hertweck C., Angew Chem Int Ed Engl 53(30), 2014
PMID: 24827417
The re-emerging role of microbial natural products in antibiotic discovery.
Genilloud O., Antonie Van Leeuwenhoek 106(1), 2014
PMID: 24923558
Genilloud O., Antonie Van Leeuwenhoek 106(1), 2014
PMID: 24923558
Analysis of the biomass composition of the demosponge Amphimedon queenslandica on Heron Island Reef, Australia.
Watson JR, Brennan TC, Degnan BM, Degnan SM, Krömer JO., Mar Drugs 12(6), 2014
PMID: 24960461
Watson JR, Brennan TC, Degnan BM, Degnan SM, Krömer JO., Mar Drugs 12(6), 2014
PMID: 24960461
Calyculin biogenesis from a pyrophosphate protoxin produced by a sponge symbiont.
Wakimoto T, Egami Y, Nakashima Y, Wakimoto Y, Mori T, Awakawa T, Ito T, Kenmoku H, Asakawa Y, Piel J, Abe I., Nat Chem Biol 10(8), 2014
PMID: 24974231
Wakimoto T, Egami Y, Nakashima Y, Wakimoto Y, Mori T, Awakawa T, Ito T, Kenmoku H, Asakawa Y, Piel J, Abe I., Nat Chem Biol 10(8), 2014
PMID: 24974231
Revealing microbial functional activities in the Red Sea sponge Stylissa carteri by metatranscriptomics.
Moitinho-Silva L, Seridi L, Ryu T, Voolstra CR, Ravasi T, Hentschel U., Environ Microbiol 16(12), 2014
PMID: 24920529
Moitinho-Silva L, Seridi L, Ryu T, Voolstra CR, Ravasi T, Hentschel U., Environ Microbiol 16(12), 2014
PMID: 24920529
Quantification of bacterial and archaeal symbionts in high and low microbial abundance sponges using real-time PCR.
Bayer K, Kamke J, Hentschel U., FEMS Microbiol Ecol 89(3), 2014
PMID: 24942664
Bayer K, Kamke J, Hentschel U., FEMS Microbiol Ecol 89(3), 2014
PMID: 24942664
Diversity and biotechnological potential of microorganisms associated with marine sponges.
Fuerst JA., Appl Microbiol Biotechnol 98(17), 2014
PMID: 25005058
Fuerst JA., Appl Microbiol Biotechnol 98(17), 2014
PMID: 25005058
Natural products: Sponge symbionts play defense.
Balskus EP., Nat Chem Biol 10(8), 2014
PMID: 25036309
Balskus EP., Nat Chem Biol 10(8), 2014
PMID: 25036309
Recent advances in genomic DNA sequencing of microbial species from single cells.
Lasken RS, McLean JS., Nat Rev Genet 15(9), 2014
PMID: 25091868
Lasken RS, McLean JS., Nat Rev Genet 15(9), 2014
PMID: 25091868
Marine sponge derived natural products between 2001 and 2010: trends and opportunities for discovery of bioactives.
Mehbub MF, Lei J, Franco C, Zhang W., Mar Drugs 12(8), 2014
PMID: 25196730
Mehbub MF, Lei J, Franco C, Zhang W., Mar Drugs 12(8), 2014
PMID: 25196730
Mining the metabiome: identifying novel natural products from microbial communities.
Milshteyn A, Schneider JS, Brady SF., Chem Biol 21(9), 2014
PMID: 25237864
Milshteyn A, Schneider JS, Brady SF., Chem Biol 21(9), 2014
PMID: 25237864
Production of avaroferrin and putrebactin by heterologous expression of a deep-sea metagenomic DNA.
Fujita MJ, Sakai R., Mar Drugs 12(9), 2014
PMID: 25222668
Fujita MJ, Sakai R., Mar Drugs 12(9), 2014
PMID: 25222668
GeoChip-based insights into the microbial functional gene repertoire of marine sponges (high microbial abundance, low microbial abundance) and seawater.
Bayer K, Moitinho-Silva L, Brümmer F, Cannistraci CV, Ravasi T, Hentschel U., FEMS Microbiol Ecol 90(3), 2014
PMID: 25318900
Bayer K, Moitinho-Silva L, Brümmer F, Cannistraci CV, Ravasi T, Hentschel U., FEMS Microbiol Ecol 90(3), 2014
PMID: 25318900
Pezizomycotina dominates the fungal communities of South China Sea sponges Theonella swinhoei and Xestospongia testudinaria.
Jin L, Liu F, Sun W, Zhang F, Karuppiah V, Li Z., FEMS Microbiol Ecol 90(3), 2014
PMID: 25348120
Jin L, Liu F, Sun W, Zhang F, Karuppiah V, Li Z., FEMS Microbiol Ecol 90(3), 2014
PMID: 25348120
Think laterally: horizontal gene transfer from symbiotic microbes may extend the phenotype of marine sessile hosts.
Degnan SM., Front Microbiol 5(), 2014
PMID: 25477875
Degnan SM., Front Microbiol 5(), 2014
PMID: 25477875
Characterisation of non-autoinducing tropodithietic Acid (TDA) production from marine sponge Pseudovibrio species.
Harrington C, Reen FJ, Mooij MJ, Stewart FA, Chabot JB, Guerra AF, Glöckner FO, Nielsen KF, Gram L, Dobson AD, Adams C, O'Gara F., Mar Drugs 12(12), 2014
PMID: 25513851
Harrington C, Reen FJ, Mooij MJ, Stewart FA, Chabot JB, Guerra AF, Glöckner FO, Nielsen KF, Gram L, Dobson AD, Adams C, O'Gara F., Mar Drugs 12(12), 2014
PMID: 25513851
66 References
Daten bereitgestellt von Europe PubMed Central.
Microbial diversity and the genetic nature of microbial species.
Achtman M, Wagner M., Nat. Rev. Microbiol. 6(6), 2008
PMID: 18461076
Achtman M, Wagner M., Nat. Rev. Microbiol. 6(6), 2008
PMID: 18461076
Metagenomic approaches to natural products from free-living and symbiotic organisms.
Brady SF, Simmons L, Kim JH, Schmidt EW., Nat Prod Rep 26(11), 2009
PMID: 19844642
Brady SF, Simmons L, Kim JH, Schmidt EW., Nat Prod Rep 26(11), 2009
PMID: 19844642
Approaches to capturing and designing biologically active small molecules produced by uncultured microbes.
Piel J., Annu. Rev. Microbiol. 65(), 2011
PMID: 21682647
Piel J., Annu. Rev. Microbiol. 65(), 2011
PMID: 21682647
Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei.
Piel J, Hui D, Wen G, Butzke D, Platzer M, Fusetani N, Matsunaga S., Proc. Natl. Acad. Sci. U.S.A. 101(46), 2004
PMID: 15520376
Piel J, Hui D, Wen G, Butzke D, Platzer M, Fusetani N, Matsunaga S., Proc. Natl. Acad. Sci. U.S.A. 101(46), 2004
PMID: 15520376
Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides.
Freeman MF, Gurgui C, Helf MJ, Morinaka BI, Uria AR, Oldham NJ, Sahl HG, Matsunaga S, Piel J., Science 338(6105), 2012
PMID: 22983711
Freeman MF, Gurgui C, Helf MJ, Morinaka BI, Uria AR, Oldham NJ, Sahl HG, Matsunaga S, Piel J., Science 338(6105), 2012
PMID: 22983711
Molecular evidence for a uniform microbial community in sponges from different oceans.
Hentschel U, Hopke J, Horn M, Friedrich AB, Wagner M, Hacker J, Moore BS., Appl. Environ. Microbiol. 68(9), 2002
PMID: 12200297
Hentschel U, Hopke J, Horn M, Friedrich AB, Wagner M, Hacker J, Moore BS., Appl. Environ. Microbiol. 68(9), 2002
PMID: 12200297
Sponge-associated microorganisms: evolution, ecology, and biotechnological potential.
Taylor MW, Radax R, Steger D, Wagner M., Microbiol. Mol. Biol. Rev. 71(2), 2007
PMID: 17554047
Taylor MW, Radax R, Steger D, Wagner M., Microbiol. Mol. Biol. Rev. 71(2), 2007
PMID: 17554047
Genomic insights into the marine sponge microbiome.
Hentschel U, Piel J, Degnan SM, Taylor MW., Nat. Rev. Microbiol. 10(9), 2012
PMID: 22842661
Hentschel U, Piel J, Degnan SM, Taylor MW., Nat. Rev. Microbiol. 10(9), 2012
PMID: 22842661
AUTHOR UNKNOWN, 0
Something from (almost) nothing: the impact of multiple displacement amplification on microbial ecology.
Binga EK, Lasken RS, Neufeld JD., ISME J 2(3), 2008
PMID: 18256705
Binga EK, Lasken RS, Neufeld JD., ISME J 2(3), 2008
PMID: 18256705
Single-cell genomics reveals the lifestyle of Poribacteria, a candidate phylum symbiotically associated with marine sponges.
Siegl A, Kamke J, Hochmuth T, Piel J, Richter M, Liang C, Dandekar T, Hentschel U., ISME J 5(1), 2010
PMID: 20613790
Siegl A, Kamke J, Hochmuth T, Piel J, Richter M, Liang C, Dandekar T, Hentschel U., ISME J 5(1), 2010
PMID: 20613790
Single cell genome amplification accelerates identification of the apratoxin biosynthetic pathway from a complex microbial assemblage.
Grindberg RV, Ishoey T, Brinza D, Esquenazi E, Coates RC, Liu WT, Gerwick L, Dorrestein PC, Pevzner P, Lasken R, Gerwick WH., PLoS ONE 6(4), 2011
PMID: 21533272
Grindberg RV, Ishoey T, Brinza D, Esquenazi E, Coates RC, Liu WT, Gerwick L, Dorrestein PC, Pevzner P, Lasken R, Gerwick WH., PLoS ONE 6(4), 2011
PMID: 21533272
Two classes of metabolites from Theonella swinhoei are localized in distinct populations of bacterial symbionts.
Bewley CA, Holland ND, Faulkner DJ., Experientia 52(7), 1996
PMID: 8698116
Bewley CA, Holland ND, Faulkner DJ., Experientia 52(7), 1996
PMID: 8698116
AUTHOR UNKNOWN, 0
Genomic DNA amplification from a single bacterium.
Raghunathan A, Ferguson HR Jr, Bornarth CJ, Song W, Driscoll M, Lasken RS., Appl. Environ. Microbiol. 71(6), 2005
PMID: 15933038
Raghunathan A, Ferguson HR Jr, Bornarth CJ, Song W, Driscoll M, Lasken RS., Appl. Environ. Microbiol. 71(6), 2005
PMID: 15933038
Insights into the phylogeny and coding potential of microbial dark matter.
Rinke C, Schwientek P, Sczyrba A, Ivanova NN, Anderson IJ, Cheng JF, Darling A, Malfatti S, Swan BK, Gies EA, Dodsworth JA, Hedlund BP, Tsiamis G, Sievert SM, Liu WT, Eisen JA, Hallam SJ, Kyrpides NC, Stepanauskas R, Rubin EM, Hugenholtz P, Woyke T., Nature 499(7459), 2013
PMID: 23851394
Rinke C, Schwientek P, Sczyrba A, Ivanova NN, Anderson IJ, Cheng JF, Darling A, Malfatti S, Swan BK, Gies EA, Dodsworth JA, Hedlund BP, Tsiamis G, Sievert SM, Liu WT, Eisen JA, Hallam SJ, Kyrpides NC, Stepanauskas R, Rubin EM, Hugenholtz P, Woyke T., Nature 499(7459), 2013
PMID: 23851394
Efficient de novo assembly of single-cell bacterial genomes from short-read data sets.
Chitsaz H, Yee-Greenbaum JL, Tesler G, Lombardo MJ, Dupont CL, Badger JH, Novotny M, Rusch DB, Fraser LJ, Gormley NA, Schulz-Trieglaff O, Smith GP, Evers DJ, Pevzner PA, Lasken RS., Nat. Biotechnol. 29(10), 2011
PMID: 21926975
Chitsaz H, Yee-Greenbaum JL, Tesler G, Lombardo MJ, Dupont CL, Badger JH, Novotny M, Rusch DB, Fraser LJ, Gormley NA, Schulz-Trieglaff O, Smith GP, Evers DJ, Pevzner PA, Lasken RS., Nat. Biotechnol. 29(10), 2011
PMID: 21926975
Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms.
Fischbach MA, Walsh CT., Chem. Rev. 106(8), 2006
PMID: 16895337
Fischbach MA, Walsh CT., Chem. Rev. 106(8), 2006
PMID: 16895337
The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases.
Stachelhaus T, Mootz HD, Marahiel MA., Chem. Biol. 6(8), 1999
PMID: 10421756
Stachelhaus T, Mootz HD, Marahiel MA., Chem. Biol. 6(8), 1999
PMID: 10421756
Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains.
Challis GL, Ravel J, Townsend CA., Chem. Biol. 7(3), 2000
PMID: 10712928
Challis GL, Ravel J, Townsend CA., Chem. Biol. 7(3), 2000
PMID: 10712928
NRPSpredictor2--a web server for predicting NRPS adenylation domain specificity.
Rottig M, Medema MH, Blin K, Weber T, Rausch C, Kohlbacher O., Nucleic Acids Res. 39(Web Server issue), 2011
PMID: 21558170
Rottig M, Medema MH, Blin K, Weber T, Rausch C, Kohlbacher O., Nucleic Acids Res. 39(Web Server issue), 2011
PMID: 21558170
AUTHOR UNKNOWN, 0
Expansion of ribosomally produced natural products: a nitrile hydratase- and Nif11-related precursor family.
Haft DH, Basu MK, Mitchell DA., BMC Biol. 8(), 2010
PMID: 20500830
Haft DH, Basu MK, Mitchell DA., BMC Biol. 8(), 2010
PMID: 20500830
Mass spectral molecular networking of living microbial colonies.
Watrous J, Roach P, Alexandrov T, Heath BS, Yang JY, Kersten RD, van der Voort M, Pogliano K, Gross H, Raaijmakers JM, Moore BS, Laskin J, Bandeira N, Dorrestein PC., Proc. Natl. Acad. Sci. U.S.A. 109(26), 2012
PMID: 22586093
Watrous J, Roach P, Alexandrov T, Heath BS, Yang JY, Kersten RD, van der Voort M, Pogliano K, Gross H, Raaijmakers JM, Moore BS, Laskin J, Bandeira N, Dorrestein PC., Proc. Natl. Acad. Sci. U.S.A. 109(26), 2012
PMID: 22586093
Adenylation enzyme characterization using gamma -(18)O(4)-ATP pyrophosphate exchange.
Phelan VV, Du Y, McLean JA, Bachmann BO., Chem. Biol. 16(5), 2009
PMID: 19477411
Phelan VV, Du Y, McLean JA, Bachmann BO., Chem. Biol. 16(5), 2009
PMID: 19477411
Mutation of L-2,3-diaminopropionic acid synthase genes blocks staphyloferrin B synthesis in Staphylococcus aureus.
Beasley FC, Cheung J, Heinrichs DE., BMC Microbiol. 11(), 2011
PMID: 21906287
Beasley FC, Cheung J, Heinrichs DE., BMC Microbiol. 11(), 2011
PMID: 21906287
Identification of the bacterial symbiont Entotheonella sp. in the mesohyl of the marine sponge Discodermia sp.
Bruck WM, Sennett SH, Pomponi SA, Willenz P, McCarthy PJ., ISME J 2(3), 2008
PMID: 18256706
Bruck WM, Sennett SH, Pomponi SA, Willenz P, McCarthy PJ., ISME J 2(3), 2008
PMID: 18256706
Linking chemical and microbial diversity in marine sponges: possible role for poribacteria as producers of methyl-branched fatty acids.
Hochmuth T, Niederkruger H, Gernert C, Siegl A, Taudien S, Platzer M, Crews P, Hentschel U, Piel J., Chembiochem 11(18), 2010
PMID: 21077090
Hochmuth T, Niederkruger H, Gernert C, Siegl A, Taudien S, Platzer M, Crews P, Hentschel U, Piel J., Chembiochem 11(18), 2010
PMID: 21077090
Impact of culture-independent studies on the emerging phylogenetic view of bacterial diversity.
Hugenholtz P, Goebel BM, Pace NR., J. Bacteriol. 180(18), 1998
PMID: 9733676
Hugenholtz P, Goebel BM, Pace NR., J. Bacteriol. 180(18), 1998
PMID: 9733676
The Genome of Nitrospina gracilis Illuminates the Metabolism and Evolution of the Major Marine Nitrite Oxidizer.
Lucker S, Nowka B, Rattei T, Spieck E, Daims H., Front Microbiol 4(), 2013
PMID: 23439773
Lucker S, Nowka B, Rattei T, Spieck E, Daims H., Front Microbiol 4(), 2013
PMID: 23439773
AUTHOR UNKNOWN, 0
Cellular origin of chlorinated diketopiperazines in the dictyoceratid sponge Dysidea herbacea (Keller).
Flowers AE, Garson MJ, Webb RI, Dumdei EJ, Charan RD., Cell Tissue Res. 292(3), 1998
PMID: 9582417
Flowers AE, Garson MJ, Webb RI, Dumdei EJ, Charan RD., Cell Tissue Res. 292(3), 1998
PMID: 9582417
Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting.
Fisch KM, Gurgui C, Heycke N, van der Sar SA, Anderson SA, Webb VL, Taudien S, Platzer M, Rubio BK, Robinson SJ, Crews P, Piel J., Nat. Chem. Biol. 5(7), 2009
PMID: 19448639
Fisch KM, Gurgui C, Heycke N, van der Sar SA, Anderson SA, Webb VL, Taudien S, Platzer M, Rubio BK, Robinson SJ, Crews P, Piel J., Nat. Chem. Biol. 5(7), 2009
PMID: 19448639
Pederin-type pathways of uncultivated bacterial symbionts: analysis of o-methyltransferases and generation of a biosynthetic hybrid.
Zimmermann K, Engeser M, Blunt JW, Munro MH, Piel J., J. Am. Chem. Soc. 131(8), 2009
PMID: 19206228
Zimmermann K, Engeser M, Blunt JW, Munro MH, Piel J., J. Am. Chem. Soc. 131(8), 2009
PMID: 19206228
An enzymatic domain for the formation of cyclic ethers in complex polyketides.
Poplau P, Frank S, Morinaka BI, Piel J., Angew. Chem. Int. Ed. Engl. 52(50), 2013
PMID: 24307486
Poplau P, Frank S, Morinaka BI, Piel J., Angew. Chem. Int. Ed. Engl. 52(50), 2013
PMID: 24307486
Metagenomic analysis reveals diverse polyketide synthase gene clusters in microorganisms associated with the marine sponge Discodermia dissoluta.
Schirmer A, Gadkari R, Reeves CD, Ibrahim F, DeLong EF, Hutchinson CR., Appl. Environ. Microbiol. 71(8), 2005
PMID: 16085882
Schirmer A, Gadkari R, Reeves CD, Ibrahim F, DeLong EF, Hutchinson CR., Appl. Environ. Microbiol. 71(8), 2005
PMID: 16085882
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).
Bentley SD, Chater KF, Cerdeno-Tarraga AM, Challis GL, Thomson NR, James KD, Harris DE, Quail MA, Kieser H, Harper D, Bateman A, Brown S, Chandra G, Chen CW, Collins M, Cronin A, Fraser A, Goble A, Hidalgo J, Hornsby T, Howarth S, Huang CH, Kieser T, Larke L, Murphy L, Oliver K, O'Neil S, Rabbinowitsch E, Rajandream MA, Rutherford K, Rutter S, Seeger K, Saunders D, Sharp S, Squares R, Squares S, Taylor K, Warren T, Wietzorrek A, Woodward J, Barrell BG, Parkhill J, Hopwood DA., Nature 417(6885), 2002
PMID: 12000953
Bentley SD, Chater KF, Cerdeno-Tarraga AM, Challis GL, Thomson NR, James KD, Harris DE, Quail MA, Kieser H, Harper D, Bateman A, Brown S, Chandra G, Chen CW, Collins M, Cronin A, Fraser A, Goble A, Hidalgo J, Hornsby T, Howarth S, Huang CH, Kieser T, Larke L, Murphy L, Oliver K, O'Neil S, Rabbinowitsch E, Rajandream MA, Rutherford K, Rutter S, Seeger K, Saunders D, Sharp S, Squares R, Squares S, Taylor K, Warren T, Wietzorrek A, Woodward J, Barrell BG, Parkhill J, Hopwood DA., Nature 417(6885), 2002
PMID: 12000953
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.
Omura S, Ikeda H, Ishikawa J, Hanamoto A, Takahashi C, Shinose M, Takahashi Y, Horikawa H, Nakazawa H, Osonoe T, Kikuchi H, Shiba T, Sakaki Y, Hattori M., Proc. Natl. Acad. Sci. U.S.A. 98(21), 2001
PMID: 11572948
Omura S, Ikeda H, Ishikawa J, Hanamoto A, Takahashi C, Shinose M, Takahashi Y, Horikawa H, Nakazawa H, Osonoe T, Kikuchi H, Shiba T, Sakaki Y, Hattori M., Proc. Natl. Acad. Sci. U.S.A. 98(21), 2001
PMID: 11572948
Complete genome sequence of the myxobacterium Sorangium cellulosum.
Schneiker S, Perlova O, Kaiser O, Gerth K, Alici A, Altmeyer MO, Bartels D, Bekel T, Beyer S, Bode E, Bode HB, Bolten CJ, Choudhuri JV, Doss S, Elnakady YA, Frank B, Gaigalat L, Goesmann A, Groeger C, Gross F, Jelsbak L, Jelsbak L, Kalinowski J, Kegler C, Knauber T, Konietzny S, Kopp M, Krause L, Krug D, Linke B, Mahmud T, Martinez-Arias R, McHardy AC, Merai M, Meyer F, Mormann S, Munoz-Dorado J, Perez J, Pradella S, Rachid S, Raddatz G, Rosenau F, Ruckert C, Sasse F, Scharfe M, Schuster SC, Suen G, Treuner-Lange A, Velicer GJ, Vorholter FJ, Weissman KJ, Welch RD, Wenzel SC, Whitworth DE, Wilhelm S, Wittmann C, Blocker H, Puhler A, Muller R., Nat. Biotechnol. 25(11), 2007
PMID: 17965706
Schneiker S, Perlova O, Kaiser O, Gerth K, Alici A, Altmeyer MO, Bartels D, Bekel T, Beyer S, Bode E, Bode HB, Bolten CJ, Choudhuri JV, Doss S, Elnakady YA, Frank B, Gaigalat L, Goesmann A, Groeger C, Gross F, Jelsbak L, Jelsbak L, Kalinowski J, Kegler C, Knauber T, Konietzny S, Kopp M, Krause L, Krug D, Linke B, Mahmud T, Martinez-Arias R, McHardy AC, Merai M, Meyer F, Mormann S, Munoz-Dorado J, Perez J, Pradella S, Rachid S, Raddatz G, Rosenau F, Ruckert C, Sasse F, Scharfe M, Schuster SC, Suen G, Treuner-Lange A, Velicer GJ, Vorholter FJ, Weissman KJ, Welch RD, Wenzel SC, Whitworth DE, Wilhelm S, Wittmann C, Blocker H, Puhler A, Muller R., Nat. Biotechnol. 25(11), 2007
PMID: 17965706
Highly plastic genome of Microcystis aeruginosa PCC 7806, a ubiquitous toxic freshwater cyanobacterium.
Frangeul L, Quillardet P, Castets AM, Humbert JF, Matthijs HC, Cortez D, Tolonen A, Zhang CC, Gribaldo S, Kehr JC, Zilliges Y, Ziemert N, Becker S, Talla E, Latifi A, Billault A, Lepelletier A, Dittmann E, Bouchier C, de Marsac NT., BMC Genomics 9(), 2008
PMID: 18534010
Frangeul L, Quillardet P, Castets AM, Humbert JF, Matthijs HC, Cortez D, Tolonen A, Zhang CC, Gribaldo S, Kehr JC, Zilliges Y, Ziemert N, Becker S, Talla E, Latifi A, Billault A, Lepelletier A, Dittmann E, Bouchier C, de Marsac NT., BMC Genomics 9(), 2008
PMID: 18534010
Compartmentalized function through cell differentiation in filamentous cyanobacteria.
Flores E, Herrero A., Nat. Rev. Microbiol. 8(1), 2010
PMID: 19966815
Flores E, Herrero A., Nat. Rev. Microbiol. 8(1), 2010
PMID: 19966815
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.
Mast Y, Weber T, Golz M, Ort-Winklbauer R, Gondran A, Wohlleben W, Schinko E., Microb Biotechnol 4(2), 2010
PMID: 21342465
Mast Y, Weber T, Golz M, Ort-Winklbauer R, Gondran A, Wohlleben W, Schinko E., Microb Biotechnol 4(2), 2010
PMID: 21342465
The RAST Server: rapid annotations using subsystems technology.
Aziz RK, Bartels D, Best AA, DeJongh M, Disz T, Edwards RA, Formsma K, Gerdes S, Glass EM, Kubal M, Meyer F, Olsen GJ, Olson R, Osterman AL, Overbeek RA, McNeil LK, Paarmann D, Paczian T, Parrello B, Pusch GD, Reich C, Stevens R, Vassieva O, Vonstein V, Wilke A, Zagnitko O., BMC Genomics 9(), 2008
PMID: 18261238
Aziz RK, Bartels D, Best AA, DeJongh M, Disz T, Edwards RA, Formsma K, Gerdes S, Glass EM, Kubal M, Meyer F, Olsen GJ, Olson R, Osterman AL, Overbeek RA, McNeil LK, Paarmann D, Paczian T, Parrello B, Pusch GD, Reich C, Stevens R, Vassieva O, Vonstein V, Wilke A, Zagnitko O., BMC Genomics 9(), 2008
PMID: 18261238
antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences.
Medema MH, Blin K, Cimermancic P, de Jager V, Zakrzewski P, Fischbach MA, Weber T, Takano E, Breitling R., Nucleic Acids Res. 39(Web Server issue), 2011
PMID: 21672958
Medema MH, Blin K, Cimermancic P, de Jager V, Zakrzewski P, Fischbach MA, Weber T, Takano E, Breitling R., Nucleic Acids Res. 39(Web Server issue), 2011
PMID: 21672958
Chapter 8. Methods for in silico prediction of microbial polyketide and nonribosomal peptide biosynthetic pathways from DNA sequence data.
Bachmann BO, Ravel J., Meth. Enzymol. 458(), 2009
PMID: 19374984
Bachmann BO, Ravel J., Meth. Enzymol. 458(), 2009
PMID: 19374984
eMZed: an open source framework in Python for rapid and interactive development of LC/MS data analysis workflows.
Kiefer P, Schmitt U, Vorholt JA., Bioinformatics 29(7), 2013
PMID: 23418185
Kiefer P, Schmitt U, Vorholt JA., Bioinformatics 29(7), 2013
PMID: 23418185
Synthesis of RNA by dissociated cells of the sea urchin embryo.
Spiegel M, Rubinstein NA., Exp. Cell Res. 70(2), 1972
PMID: 5058914
Spiegel M, Rubinstein NA., Exp. Cell Res. 70(2), 1972
PMID: 5058914
r2cat: synteny plots and comparative assembly.
Husemann P, Stoye J., Bioinformatics 26(4), 2009
PMID: 20015948
Husemann P, Stoye J., Bioinformatics 26(4), 2009
PMID: 20015948
Isolation and phylogenetic analysis of bacteria with antimicrobial activities from the Mediterranean sponges Aplysina aerophoba and Aplysina cavernicola.
Hentschel U, Schmid M, Wagner M, Fieseler L, Gernert C, Hacker J., FEMS Microbiol. Ecol. 35(3), 2001
PMID: 11311441
Hentschel U, Schmid M, Wagner M, Fieseler L, Gernert C, Hacker J., FEMS Microbiol. Ecol. 35(3), 2001
PMID: 11311441
A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles.
Piel J., Proc. Natl. Acad. Sci. U.S.A. 99(22), 2002
PMID: 12381784
Piel J., Proc. Natl. Acad. Sci. U.S.A. 99(22), 2002
PMID: 12381784
AUTHOR UNKNOWN, 0
SINA: accurate high-throughput multiple sequence alignment of ribosomal RNA genes.
Pruesse E, Peplies J, Glockner FO., Bioinformatics 28(14), 2012
PMID: 22556368
Pruesse E, Peplies J, Glockner FO., Bioinformatics 28(14), 2012
PMID: 22556368
ARB: a software environment for sequence data.
Ludwig W, Strunk O, Westram R, Richter L, Meier H, Yadhukumar , Buchner A, Lai T, Steppi S, Jobb G, Forster W, Brettske I, Gerber S, Ginhart AW, Gross O, Grumann S, Hermann S, Jost R, Konig A, Liss T, Lussmann R, May M, Nonhoff B, Reichel B, Strehlow R, Stamatakis A, Stuckmann N, Vilbig A, Lenke M, Ludwig T, Bode A, Schleifer KH., Nucleic Acids Res. 32(4), 2004
PMID: 14985472
Ludwig W, Strunk O, Westram R, Richter L, Meier H, Yadhukumar , Buchner A, Lai T, Steppi S, Jobb G, Forster W, Brettske I, Gerber S, Ginhart AW, Gross O, Grumann S, Hermann S, Jost R, Konig A, Liss T, Lussmann R, May M, Nonhoff B, Reichel B, Strehlow R, Stamatakis A, Stuckmann N, Vilbig A, Lenke M, Ludwig T, Bode A, Schleifer KH., Nucleic Acids Res. 32(4), 2004
PMID: 14985472
SILVA: a comprehensive online resource for quality checked and aligned ribosomal RNA sequence data compatible with ARB.
Pruesse E, Quast C, Knittel K, Fuchs BM, Ludwig W, Peplies J, Glockner FO., Nucleic Acids Res. 35(21), 2007
PMID: 17947321
Pruesse E, Quast C, Knittel K, Fuchs BM, Ludwig W, Peplies J, Glockner FO., Nucleic Acids Res. 35(21), 2007
PMID: 17947321
FastTree 2--approximately maximum-likelihood trees for large alignments.
Price MN, Dehal PS, Arkin AP., PLoS ONE 5(3), 2010
PMID: 20224823
Price MN, Dehal PS, Arkin AP., PLoS ONE 5(3), 2010
PMID: 20224823
RAxML-Light: a tool for computing terabyte phylogenies.
Stamatakis A, Aberer AJ, Goll C, Smith SA, Berger SA, Izquierdo-Carrasco F., Bioinformatics 28(15), 2012
PMID: 22628519
Stamatakis A, Aberer AJ, Goll C, Smith SA, Berger SA, Izquierdo-Carrasco F., Bioinformatics 28(15), 2012
PMID: 22628519
RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models.
Stamatakis A., Bioinformatics 22(21), 2006
PMID: 16928733
Stamatakis A., Bioinformatics 22(21), 2006
PMID: 16928733
Structural basis of the interaction of MbtH-like proteins, putative regulators of nonribosomal peptide biosynthesis, with adenylating enzymes.
Herbst DA, Boll B, Zocher G, Stehle T, Heide L., J. Biol. Chem. 288(3), 2012
PMID: 23192349
Herbst DA, Boll B, Zocher G, Stehle T, Heide L., J. Biol. Chem. 288(3), 2012
PMID: 23192349
Non-ribosomal propeptide precursor in nocardicin A biosynthesis predicted from adenylation domain specificity dependent on the MbtH family protein NocI.
Davidsen JM, Bartley DM, Townsend CA., J. Am. Chem. Soc. 135(5), 2013
PMID: 23330869
Davidsen JM, Bartley DM, Townsend CA., J. Am. Chem. Soc. 135(5), 2013
PMID: 23330869
Insights into the biosynthesis of hormaomycin, an exceptionally complex bacterial signaling metabolite.
Hofer I, Crusemann M, Radzom M, Geers B, Flachshaar D, Cai X, Zeeck A, Piel J., Chem. Biol. 18(3), 2011
PMID: 21439483
Hofer I, Crusemann M, Radzom M, Geers B, Flachshaar D, Cai X, Zeeck A, Piel J., Chem. Biol. 18(3), 2011
PMID: 21439483
AUTHOR UNKNOWN, 0
Clustering millions of tandem mass spectra.
Frank AM, Bandeira N, Shen Z, Tanner S, Briggs SP, Smith RD, Pevzner PA., J. Proteome Res. 7(1), 2007
PMID: 18067247
Frank AM, Bandeira N, Shen Z, Tanner S, Briggs SP, Smith RD, Pevzner PA., J. Proteome Res. 7(1), 2007
PMID: 18067247
Protein identification by spectral networks analysis.
Bandeira N, Tsur D, Frank A, Pevzner PA., Proc. Natl. Acad. Sci. U.S.A. 104(15), 2007
PMID: 17404225
Bandeira N, Tsur D, Frank A, Pevzner PA., Proc. Natl. Acad. Sci. U.S.A. 104(15), 2007
PMID: 17404225
Cytoscape: a software environment for integrated models of biomolecular interaction networks.
Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, Ramage D, Amin N, Schwikowski B, Ideker T., Genome Res. 13(11), 2003
PMID: 14597658
Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, Ramage D, Amin N, Schwikowski B, Ideker T., Genome Res. 13(11), 2003
PMID: 14597658
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