Computational construction of specialized biological networks

Lee H-M, Dietz K-J, Hofestädt R (2013)
Journal of Bioinformatics and Computational Biology 11(01): 1340003.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Abstract / Bemerkung
Today we have access to more than 1500 molecular database systems inside the internet. Based on these databases and information systems, computer scientists developed and implemented different methods for the automatic integration and prediction of biological networks. The idea is to use such methods for the automatic prediction and expansion of rudimentary molecular knowledge. However, the inherent data deficiency problem concerning the properties of specialized network hampers the database- and text-mining-based network construction. This paper presents the concept concerning the computational network expansion, namely for the specific biological network-thiol-disulfide redox regulatory network. Besides, a network-contexted document retrieval system (ncDocReSy) is also introduced to assist the network reduction by providing indirectly relevant literature for user's manual curation. NcDocReSy combines literature search with biological network and ranks the retrieved literature according to the network topology. NcDocReSy is implemented as a Cytoscape plugin.
Erscheinungsjahr
2013
Zeitschriftentitel
Journal of Bioinformatics and Computational Biology
Band
11
Ausgabe
01
Seite(n)
1340003
ISSN
0219-7200
eISSN
1757-6334
Page URI
https://pub.uni-bielefeld.de/record/2560811

Zitieren

Lee H-M, Dietz K-J, Hofestädt R. Computational construction of specialized biological networks. Journal of Bioinformatics and Computational Biology. 2013;11(01):1340003.
Lee, H. - M., Dietz, K. - J., & Hofestädt, R. (2013). Computational construction of specialized biological networks. Journal of Bioinformatics and Computational Biology, 11(01), 1340003. doi:10.1142/S0219720013400039
Lee, H. - M., Dietz, K. - J., and Hofestädt, R. (2013). Computational construction of specialized biological networks. Journal of Bioinformatics and Computational Biology 11, 1340003.
Lee, H.-M., Dietz, K.-J., & Hofestädt, R., 2013. Computational construction of specialized biological networks. Journal of Bioinformatics and Computational Biology, 11(01), p 1340003.
H.-M. Lee, K.-J. Dietz, and R. Hofestädt, “Computational construction of specialized biological networks”, Journal of Bioinformatics and Computational Biology, vol. 11, 2013, pp. 1340003.
Lee, H.-M., Dietz, K.-J., Hofestädt, R.: Computational construction of specialized biological networks. Journal of Bioinformatics and Computational Biology. 11, 1340003 (2013).
Lee, Hang-Mao, Dietz, Karl-Josef, and Hofestädt, Ralf. “Computational construction of specialized biological networks”. Journal of Bioinformatics and Computational Biology 11.01 (2013): 1340003.

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