How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology?

Carrondo MJT, Alves PM, Carinhas N, Glassey J, Hesse F, Merten O-W, Micheletti M, Noll T, Oliveira R, Reichl U, Staby A, et al. (2012)
Biotechnology Journal 7(12): 1522-1529.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Carrondo, Manuel J. T.; Alves, Paula M.; Carinhas, Nuno; Glassey, Jarka; Hesse, Friedemann; Merten, Otto-Wilhelm; Micheletti, Martina; Noll, ThomasUniBi ; Oliveira, Rui; Reichl, Udo; Staby, Arne; Teixeira, Ana P.
Alle
Abstract / Bemerkung
This report highlights the potential of measurement, monitoring, modeling and control ((MC)-C-3) methodologies in animal and human cell culture technology. In particular, state-of-the-art of (MC)-C-3 technologies and their industrial relevance of existing technology are addressed. It is a summary of an expert panel discussion between biotechnologists and biochemical engineers with both academic and industrial backgrounds. The latest ascents in (MC)-C-3 are discussed from a cell culture perspective for industrial process development and production needs. The report concludes with a set of recommendations for targeting (MC)-C-3 research toward the industrial interests. These include issues of importance for biotherapeutics production, miniaturization of measurement techniques and modeling methods.
Stichworte
Stem cells; Mammalian cells; Biopharmaceuticals; Gene therapy; vectors; Viral
Erscheinungsjahr
2012
Zeitschriftentitel
Biotechnology Journal
Band
7
Ausgabe
12
Seite(n)
1522-1529
ISSN
1860-6768
Page URI
https://pub.uni-bielefeld.de/record/2553404

Zitieren

Carrondo MJT, Alves PM, Carinhas N, et al. How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology? Biotechnology Journal. 2012;7(12):1522-1529.
Carrondo, M. J. T., Alves, P. M., Carinhas, N., Glassey, J., Hesse, F., Merten, O. - W., Micheletti, M., et al. (2012). How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology? Biotechnology Journal, 7(12), 1522-1529. doi:10.1002/biot.201200226
Carrondo, M. J. T., Alves, P. M., Carinhas, N., Glassey, J., Hesse, F., Merten, O. - W., Micheletti, M., Noll, T., Oliveira, R., Reichl, U., et al. (2012). How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology? Biotechnology Journal 7, 1522-1529.
Carrondo, M.J.T., et al., 2012. How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology? Biotechnology Journal, 7(12), p 1522-1529.
M.J.T. Carrondo, et al., “How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology?”, Biotechnology Journal, vol. 7, 2012, pp. 1522-1529.
Carrondo, M.J.T., Alves, P.M., Carinhas, N., Glassey, J., Hesse, F., Merten, O.-W., Micheletti, M., Noll, T., Oliveira, R., Reichl, U., Staby, A., Teixeira, A.P., Weichert, H., Mandenius, C.-F.: How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology? Biotechnology Journal. 7, 1522-1529 (2012).
Carrondo, Manuel J. T., Alves, Paula M., Carinhas, Nuno, Glassey, Jarka, Hesse, Friedemann, Merten, Otto-Wilhelm, Micheletti, Martina, Noll, Thomas, Oliveira, Rui, Reichl, Udo, Staby, Arne, Teixeira, Ana P., Weichert, Henry, and Mandenius, Carl-Fredrik. “How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology?”. Biotechnology Journal 7.12 (2012): 1522-1529.

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