CoryneRegNet 2: An integrative bioinformatics approach for reconstruction and comparison of transcriptional regulatory networks in prokaryotes
Baumbach J, Brinkrolf K, Wittkop T, Tauch A, Rahmann S (2006)
Journal of Integrative Bioinformatics 3(2): 24.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
Download
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Autor*in
Baumbach, Jan;
Brinkrolf, KarinaUniBi;
Wittkop, Tobias;
Tauch, AndreasUniBi;
Rahmann, Sven
Einrichtung
Abstract / Bemerkung
CoryneRegNet is an ontology-based data warehouse of corynebacterial transcription factors and regulatory networks. Initially, it was designed to provide methods for the analysis and visualization of the gene regulatory network of Corynebacterium glutamicum. Now we integrated the genomes and transcriptional interactions of three other corynebacteria, C. diphtheriae, C. efficiens, and C. jeikeium into CoryneRegNet; providing comparative analysis and visualization with GraphVis. We also integrated the high-performance PSSM search tool PoSSuMsearch to detect potential transcription factor binding sites within and across species. As an application, we reconstruct in silico the regulatory network of the iron metabolism regulator DtxR in the four corynebacteria. CoryneRegNet is freely accessible at https://www.cebitec.uni-bielefeld.de/ groups/gi/software/coryneregnet/. The final slash (/) is mandatory. In order to use the GraphVis feature, Java (at least version 1.4.2) is required.
Erscheinungsjahr
2006
Zeitschriftentitel
Journal of Integrative Bioinformatics
Band
3
Ausgabe
2
Seite(n)
24
ISSN
1613-4516
Page URI
https://pub.uni-bielefeld.de/record/2499499
Zitieren
Baumbach J, Brinkrolf K, Wittkop T, Tauch A, Rahmann S. CoryneRegNet 2: An integrative bioinformatics approach for reconstruction and comparison of transcriptional regulatory networks in prokaryotes. Journal of Integrative Bioinformatics. 2006;3(2):24.
Baumbach, J., Brinkrolf, K., Wittkop, T., Tauch, A., & Rahmann, S. (2006). CoryneRegNet 2: An integrative bioinformatics approach for reconstruction and comparison of transcriptional regulatory networks in prokaryotes. Journal of Integrative Bioinformatics, 3(2), 24. doi:10.2390/biecoll-jib-2006-24
Baumbach, Jan, Brinkrolf, Karina, Wittkop, Tobias, Tauch, Andreas, and Rahmann, Sven. 2006. “CoryneRegNet 2: An integrative bioinformatics approach for reconstruction and comparison of transcriptional regulatory networks in prokaryotes”. Journal of Integrative Bioinformatics 3 (2): 24.
Baumbach, J., Brinkrolf, K., Wittkop, T., Tauch, A., and Rahmann, S. (2006). CoryneRegNet 2: An integrative bioinformatics approach for reconstruction and comparison of transcriptional regulatory networks in prokaryotes. Journal of Integrative Bioinformatics 3, 24.
Baumbach, J., et al., 2006. CoryneRegNet 2: An integrative bioinformatics approach for reconstruction and comparison of transcriptional regulatory networks in prokaryotes. Journal of Integrative Bioinformatics, 3(2), p 24.
J. Baumbach, et al., “CoryneRegNet 2: An integrative bioinformatics approach for reconstruction and comparison of transcriptional regulatory networks in prokaryotes”, Journal of Integrative Bioinformatics, vol. 3, 2006, pp. 24.
Baumbach, J., Brinkrolf, K., Wittkop, T., Tauch, A., Rahmann, S.: CoryneRegNet 2: An integrative bioinformatics approach for reconstruction and comparison of transcriptional regulatory networks in prokaryotes. Journal of Integrative Bioinformatics. 3, 24 (2006).
Baumbach, Jan, Brinkrolf, Karina, Wittkop, Tobias, Tauch, Andreas, and Rahmann, Sven. “CoryneRegNet 2: An integrative bioinformatics approach for reconstruction and comparison of transcriptional regulatory networks in prokaryotes”. Journal of Integrative Bioinformatics 3.2 (2006): 24.
Google Scholar