Visualization of omics data for systems biology
Gehlenborg N, O'Donoghue SI, Baliga NS, Goesmann A, Hibbs MA, Kitano H, Kohlbacher O, Neuweger H, Schneider R, Tenenbaum D, Gavin A-C (2010)
Nat Methods 7(3s): S56-S68.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
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Autor*in
Gehlenborg, Nils;
O'Donoghue, Sean I;
Baliga, Nitin S;
Goesmann, AlexanderUniBi ;
Hibbs, Matthew A;
Kitano, Hiroaki;
Kohlbacher, Oliver;
Neuweger, Heiko;
Schneider, Reinhard;
Tenenbaum, Dan;
Gavin, Anne-Claude
Einrichtung
Abstract / Bemerkung
High-throughput studies of biological systems are rapidly accumulating a wealth of 'omics'-scale data. Visualization is a key aspect of both the analysis and understanding of these data, and users now have many visualization methods and tools to choose from. The challenge is to create clear, meaningful and integrated visualizations that give biological insight, without being overwhelmed by the intrinsic complexity of the data. In this review, we discuss how visualization tools are being used to help interpret protein interaction, gene expression and metabolic profile data, and we highlight emerging new directions.
Erscheinungsjahr
2010
Zeitschriftentitel
Nat Methods
Band
7
Ausgabe
3s
Seite(n)
S56-S68
ISSN
1548-7091
eISSN
1548-7105
Page URI
https://pub.uni-bielefeld.de/record/1990186
Zitieren
Gehlenborg N, O'Donoghue SI, Baliga NS, et al. Visualization of omics data for systems biology. Nat Methods. 2010;7(3s):S56-S68.
Gehlenborg, N., O'Donoghue, S. I., Baliga, N. S., Goesmann, A., Hibbs, M. A., Kitano, H., Kohlbacher, O., et al. (2010). Visualization of omics data for systems biology. Nat Methods, 7(3s), S56-S68. https://doi.org/10.1038/NMETH.1436
Gehlenborg, Nils, O'Donoghue, Sean I, Baliga, Nitin S, Goesmann, Alexander, Hibbs, Matthew A, Kitano, Hiroaki, Kohlbacher, Oliver, et al. 2010. “Visualization of omics data for systems biology”. Nat Methods 7 (3s): S56-S68.
Gehlenborg, N., O'Donoghue, S. I., Baliga, N. S., Goesmann, A., Hibbs, M. A., Kitano, H., Kohlbacher, O., Neuweger, H., Schneider, R., Tenenbaum, D., et al. (2010). Visualization of omics data for systems biology. Nat Methods 7, S56-S68.
Gehlenborg, N., et al., 2010. Visualization of omics data for systems biology. Nat Methods, 7(3s), p S56-S68.
N. Gehlenborg, et al., “Visualization of omics data for systems biology”, Nat Methods, vol. 7, 2010, pp. S56-S68.
Gehlenborg, N., O'Donoghue, S.I., Baliga, N.S., Goesmann, A., Hibbs, M.A., Kitano, H., Kohlbacher, O., Neuweger, H., Schneider, R., Tenenbaum, D., Gavin, A.-C.: Visualization of omics data for systems biology. Nat Methods. 7, S56-S68 (2010).
Gehlenborg, Nils, O'Donoghue, Sean I, Baliga, Nitin S, Goesmann, Alexander, Hibbs, Matthew A, Kitano, Hiroaki, Kohlbacher, Oliver, Neuweger, Heiko, Schneider, Reinhard, Tenenbaum, Dan, and Gavin, Anne-Claude. “Visualization of omics data for systems biology”. Nat Methods 7.3s (2010): S56-S68.
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Bacterial rose garden for metagenomic SNP-based phylogeny visualization.
Alexeev D, Bibikova T, Kovarsky B, Melnikov D, Tyakht A, Govorun V., BioData Min 8(), 2015
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Alexeev D, Bibikova T, Kovarsky B, Melnikov D, Tyakht A, Govorun V., BioData Min 8(), 2015
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Unlocking proteomic heterogeneity in complex diseases through visual analytics.
Bhavnani SK, Dang B, Bellala G, Divekar R, Visweswaran S, Brasier AR, Kurosky A., Proteomics 15(8), 2015
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Bhavnani SK, Dang B, Bellala G, Divekar R, Visweswaran S, Brasier AR, Kurosky A., Proteomics 15(8), 2015
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RNA imaging. Spatially resolved, highly multiplexed RNA profiling in single cells.
Chen KH, Boettiger AN, Moffitt JR, Wang S, Zhuang X., Science 348(6233), 2015
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Chen KH, Boettiger AN, Moffitt JR, Wang S, Zhuang X., Science 348(6233), 2015
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Recent progress in the use of 'omics technologies in brassicaceous vegetables.
Witzel K, Neugart S, Ruppel S, Schreiner M, Wiesner M, Baldermann S., Front Plant Sci 6(), 2015
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Witzel K, Neugart S, Ruppel S, Schreiner M, Wiesner M, Baldermann S., Front Plant Sci 6(), 2015
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Neuroblastoma tyrosine kinase signaling networks involve FYN and LYN in endosomes and lipid rafts.
Palacios-Moreno J, Foltz L, Guo A, Stokes MP, Kuehn ED, George L, Comb M, Grimes ML., PLoS Comput Biol 11(4), 2015
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Palacios-Moreno J, Foltz L, Guo A, Stokes MP, Kuehn ED, George L, Comb M, Grimes ML., PLoS Comput Biol 11(4), 2015
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VISIONET: intuitive visualisation of overlapping transcription factor networks, with applications in cardiogenic gene discovery.
Nim HT, Furtado MB, Costa MW, Rosenthal NA, Kitano H, Boyd SE., BMC Bioinformatics 16(), 2015
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Nim HT, Furtado MB, Costa MW, Rosenthal NA, Kitano H, Boyd SE., BMC Bioinformatics 16(), 2015
PMID: 25929466
NaviCell Web Service for network-based data visualization.
Bonnet E, Viara E, Kuperstein I, Calzone L, Cohen DP, Barillot E, Zinovyev A., Nucleic Acids Res 43(w1), 2015
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Bonnet E, Viara E, Kuperstein I, Calzone L, Cohen DP, Barillot E, Zinovyev A., Nucleic Acids Res 43(w1), 2015
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Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming.
Wu Y, Li Y, Zhang H, Huang Y, Zhao P, Tang Y, Qiu X, Ying Y, Li W, Ni S, Zhang M, Liu L, Xu Y, Zhuang Q, Luo Z, Benda C, Song H, Liu B, Lai L, Liu X, Tse HF, Bao X, Chan WY, Esteban MA, Qin B, Pei D., Nat Cell Biol 17(6), 2015
PMID: 25985393
Wu Y, Li Y, Zhang H, Huang Y, Zhao P, Tang Y, Qiu X, Ying Y, Li W, Ni S, Zhang M, Liu L, Xu Y, Zhuang Q, Luo Z, Benda C, Song H, Liu B, Lai L, Liu X, Tse HF, Bao X, Chan WY, Esteban MA, Qin B, Pei D., Nat Cell Biol 17(6), 2015
PMID: 25985393
NetworkPainter: dynamic intracellular pathway animation in Cytobank.
Karr JR, Guturu H, Chen EY, Blair SL, Irish JM, Kotecha N, Covert MW., BMC Bioinformatics 16(), 2015
PMID: 26003204
Karr JR, Guturu H, Chen EY, Blair SL, Irish JM, Kotecha N, Covert MW., BMC Bioinformatics 16(), 2015
PMID: 26003204
FunRich: An open access standalone functional enrichment and interaction network analysis tool.
Pathan M, Keerthikumar S, Ang CS, Gangoda L, Quek CY, Williamson NA, Mouradov D, Sieber OM, Simpson RJ, Salim A, Bacic A, Hill AF, Stroud DA, Ryan MT, Agbinya JI, Mariadason JM, Burgess AW, Mathivanan S., Proteomics 15(15), 2015
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Pathan M, Keerthikumar S, Ang CS, Gangoda L, Quek CY, Williamson NA, Mouradov D, Sieber OM, Simpson RJ, Salim A, Bacic A, Hill AF, Stroud DA, Ryan MT, Agbinya JI, Mariadason JM, Burgess AW, Mathivanan S., Proteomics 15(15), 2015
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Rapid generation of secondary fibroblasts through teratoma formation.
Cho SM, Park JS, Min B, Kwon S, Kang YK., Biotechniques 59(1), 2015
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Cho SM, Park JS, Min B, Kwon S, Kang YK., Biotechniques 59(1), 2015
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Choosing Cell Fate Through a Dynamic Cell Cycle.
Chen X, Hartman A, Guo S., Curr Stem Cell Rep 1(3), 2015
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Chen X, Hartman A, Guo S., Curr Stem Cell Rep 1(3), 2015
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Generation of Human Induced Pluripotent Stem Cells from Extraembryonic Tissues of Fetuses Affected by Monogenic Diseases.
Spitalieri P, Talarico RV, Botta A, Murdocca M, D'Apice MR, Orlandi A, Giardina E, Santoro M, Brancati F, Novelli G, Sangiuolo F., Cell Reprogram 17(4), 2015
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Spitalieri P, Talarico RV, Botta A, Murdocca M, D'Apice MR, Orlandi A, Giardina E, Santoro M, Brancati F, Novelli G, Sangiuolo F., Cell Reprogram 17(4), 2015
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Genomewide effects of peroxisome proliferator-activated receptor gamma in macrophages and dendritic cells--revealing complexity through systems biology.
Cuaranta-Monroy I, Kiss M, Simandi Z, Nagy L., Eur J Clin Invest 45(9), 2015
PMID: 26251129
Cuaranta-Monroy I, Kiss M, Simandi Z, Nagy L., Eur J Clin Invest 45(9), 2015
PMID: 26251129
PathwayMatrix: visualizing binary relationships between proteins in biological pathways.
Dang TN, Murray P, Forbes AG., BMC Proc 9(suppl 6 proceedings of the 5th symposium on biological ), 2015
PMID: 26361499
Dang TN, Murray P, Forbes AG., BMC Proc 9(suppl 6 proceedings of the 5th symposium on biological ), 2015
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DeDaL: Cytoscape 3 app for producing and morphing data-driven and structure-driven network layouts.
Czerwinska U, Calzone L, Barillot E, Zinovyev A., BMC Syst Biol 9(), 2015
PMID: 26271256
Czerwinska U, Calzone L, Barillot E, Zinovyev A., BMC Syst Biol 9(), 2015
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Visualizing genome and systems biology: technologies, tools, implementation techniques and trends, past, present and future.
Pavlopoulos GA, Malliarakis D, Papanikolaou N, Theodosiou T, Enright AJ, Iliopoulos I., Gigascience 4(), 2015
PMID: 26309733
Pavlopoulos GA, Malliarakis D, Papanikolaou N, Theodosiou T, Enright AJ, Iliopoulos I., Gigascience 4(), 2015
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Data integration in biological research: an overview.
Lapatas V, Stefanidakis M, Jimenez RC, Via A, Schneider MV., J Biol Res (Thessalon) 22(1), 2015
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Lapatas V, Stefanidakis M, Jimenez RC, Via A, Schneider MV., J Biol Res (Thessalon) 22(1), 2015
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Publisher’s Note:Abstraction for data integration:Fusing mammalian molecular, cellular and phenotype big datasets for better knowledge extraction.
Rouillard AD, Wang Z, Ma'ayan A., Comput Biol Chem 58(), 2015
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Rouillard AD, Wang Z, Ma'ayan A., Comput Biol Chem 58(), 2015
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microRNAs as pharmacogenomic biomarkers for drug efficacy and drug safety assessment.
Koturbash I, Tolleson WH, Guo L, Yu D, Chen S, Hong H, Mattes W, Ning B., Biomark Med 9(11), 2015
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Koturbash I, Tolleson WH, Guo L, Yu D, Chen S, Hong H, Mattes W, Ning B., Biomark Med 9(11), 2015
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Facilitating the use of large-scale biological data and tools in the era of translational bioinformatics.
Kouskoumvekaki I, Shublaq N, Brunak S., Brief Bioinform 15(6), 2014
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Kouskoumvekaki I, Shublaq N, Brunak S., Brief Bioinform 15(6), 2014
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Procedures for the biochemical enrichment and proteomic analysis of the cytoskeletome.
Choi S, Kelber J, Jiang X, Strnadel J, Fujimura K, Pasillas M, Coppinger J, Klemke R., Anal Biochem 446(), 2014
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Choi S, Kelber J, Jiang X, Strnadel J, Fujimura K, Pasillas M, Coppinger J, Klemke R., Anal Biochem 446(), 2014
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Protter: interactive protein feature visualization and integration with experimental proteomic data.
Omasits U, Ahrens CH, Müller S, Wollscheid B., Bioinformatics 30(6), 2014
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Omasits U, Ahrens CH, Müller S, Wollscheid B., Bioinformatics 30(6), 2014
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C/EBPα poises B cells for rapid reprogramming into induced pluripotent stem cells.
Di Stefano B, Sardina JL, van Oevelen C, Collombet S, Kallin EM, Vicent GP, Lu J, Thieffry D, Beato M, Graf T., Nature 506(7487), 2014
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Di Stefano B, Sardina JL, van Oevelen C, Collombet S, Kallin EM, Vicent GP, Lu J, Thieffry D, Beato M, Graf T., Nature 506(7487), 2014
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Ondex Web: web-based visualization and exploration of heterogeneous biological networks.
Taubert J, Hassani-Pak K, Castells-Brooke N, Rawlings CJ., Bioinformatics 30(7), 2014
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Taubert J, Hassani-Pak K, Castells-Brooke N, Rawlings CJ., Bioinformatics 30(7), 2014
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Integration, visualization and analysis of human interactome.
Pastrello C, Pasini E, Kotlyar M, Otasek D, Wong S, Sangrar W, Rahmati S, Jurisica I., Biochem Biophys Res Commun 445(4), 2014
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Pastrello C, Pasini E, Kotlyar M, Otasek D, Wong S, Sangrar W, Rahmati S, Jurisica I., Biochem Biophys Res Commun 445(4), 2014
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BiNA: a visual analytics tool for biological network data.
Gerasch A, Faber D, Küntzer J, Niermann P, Kohlbacher O, Lenhof HP, Kaufmann M., PLoS One 9(2), 2014
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Gerasch A, Faber D, Küntzer J, Niermann P, Kohlbacher O, Lenhof HP, Kaufmann M., PLoS One 9(2), 2014
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PPI layouts: BioJS components for the display of Protein-Protein Interactions.
Salazar GA, Meintjes A, Mulder N., F1000Res 3(), 2014
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Salazar GA, Meintjes A, Mulder N., F1000Res 3(), 2014
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Meta-analysis of pathway enrichment: combining independent and dependent omics data sets.
Kaever A, Landesfeind M, Feussner K, Morgenstern B, Feussner I, Meinicke P., PLoS One 9(2), 2014
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Kaever A, Landesfeind M, Feussner K, Morgenstern B, Feussner I, Meinicke P., PLoS One 9(2), 2014
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Predictive in silico off-target profiling in drug discovery.
Schmidt F, Matter H, Hessler G, Czich A., Future Med Chem 6(3), 2014
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Schmidt F, Matter H, Hessler G, Czich A., Future Med Chem 6(3), 2014
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Plant systems biology: insights, advances and challenges.
Sheth BP, Thaker VS., Planta 240(1), 2014
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Sheth BP, Thaker VS., Planta 240(1), 2014
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Interactive Visualization for Patient-to-Patient Comparison.
Nguyen QV, Nelmes G, Huang ML, Simoff S, Catchpoole D., Genomics Inform 12(1), 2014
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Nguyen QV, Nelmes G, Huang ML, Simoff S, Catchpoole D., Genomics Inform 12(1), 2014
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New insights into Dehalococcoides mccartyi metabolism from a reconstructed metabolic network-based systems-level analysis of D. mccartyi transcriptomes.
Islam MA, Waller AS, Hug LA, Provart NJ, Edwards EA, Mahadevan R., PLoS One 9(4), 2014
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Islam MA, Waller AS, Hug LA, Provart NJ, Edwards EA, Mahadevan R., PLoS One 9(4), 2014
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Scientists' sense making when hypothesizing about disease mechanisms from expression data and their needs for visualization support.
Mirel B, Görg C., BMC Bioinformatics 15(), 2014
PMID: 24766796
Mirel B, Görg C., BMC Bioinformatics 15(), 2014
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A web-based protein interaction network visualizer.
Salazar GA, Meintjes A, Mazandu GK, Rapanoël HA, Akinola RO, Mulder NJ., BMC Bioinformatics 15(), 2014
PMID: 24885165
Salazar GA, Meintjes A, Mazandu GK, Rapanoël HA, Akinola RO, Mulder NJ., BMC Bioinformatics 15(), 2014
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Proteogenomic convergence for understanding cancer pathways and networks.
Boja ES, Rodriguez H., Clin Proteomics 11(1), 2014
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Boja ES, Rodriguez H., Clin Proteomics 11(1), 2014
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How implementation of systems biology into clinical trials accelerates understanding of diseases.
Bielekova B, Vodovotz Y, An G, Hallenbeck J., Front Neurol 5(), 2014
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Bielekova B, Vodovotz Y, An G, Hallenbeck J., Front Neurol 5(), 2014
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eXamine: exploring annotated modules in networks.
Dinkla K, El-Kebir M, Bucur CI, Siderius M, Smit MJ, Westenberg MA, Klau GW., BMC Bioinformatics 15(), 2014
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Dinkla K, El-Kebir M, Bucur CI, Siderius M, Smit MJ, Westenberg MA, Klau GW., BMC Bioinformatics 15(), 2014
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dendsort: modular leaf ordering methods for dendrogram representations in R.
Sakai R, Winand R, Verbeiren T, Moere AV, Aerts J., F1000Res 3(), 2014
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Sakai R, Winand R, Verbeiren T, Moere AV, Aerts J., F1000Res 3(), 2014
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dendsort: modular leaf ordering methods for dendrogram representations in R
Sakai R, Winand R, Verbeiren T, Moere AV, Aerts J., 2014
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Sakai R, Winand R, Verbeiren T, Moere AV, Aerts J., 2014
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Grouping annotations on the subcellular layered interactome demonstrates enhanced autophagy activity in a recurrent experimental autoimmune uveitis T cell line.
Jia X, Li J, Shi D, Zhao Y, Dong Y, Ju H, Yang J, Sun J, Li X, Ren H., PLoS One 9(8), 2014
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Jia X, Li J, Shi D, Zhao Y, Dong Y, Ju H, Yang J, Sun J, Li X, Ren H., PLoS One 9(8), 2014
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Integrated network analysis and effective tools in plant systems biology.
Fukushima A, Kanaya S, Nishida K., Front Plant Sci 5(), 2014
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Fukushima A, Kanaya S, Nishida K., Front Plant Sci 5(), 2014
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Data mining in the Life Sciences with Random Forest: a walk in the park or lost in the jungle?
Touw WG, Bayjanov JR, Overmars L, Backus L, Boekhorst J, Wels M, van Hijum SA., Brief Bioinform 14(3), 2013
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Touw WG, Bayjanov JR, Overmars L, Backus L, Boekhorst J, Wels M, van Hijum SA., Brief Bioinform 14(3), 2013
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Plasma microRNA profiles for bladder cancer detection.
Adam L, Wszolek MF, Liu CG, Jing W, Diao L, Zien A, Zhang JD, Jackson D, Dinney CP., Urol Oncol 31(8), 2013
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Adam L, Wszolek MF, Liu CG, Jing W, Diao L, Zien A, Zhang JD, Jackson D, Dinney CP., Urol Oncol 31(8), 2013
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Analytical glycobiology at high sensitivity: current approaches and directions.
Novotny MV, Alley WR, Mann BF., Glycoconj J 30(2), 2013
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Novotny MV, Alley WR, Mann BF., Glycoconj J 30(2), 2013
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The Comparative Toxicogenomics Database: update 2013.
Davis AP, Murphy CG, Johnson R, Lay JM, Lennon-Hopkins K, Saraceni-Richards C, Sciaky D, King BL, Rosenstein MC, Wiegers TC, Mattingly CJ., Nucleic Acids Res 41(database issue), 2013
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Davis AP, Murphy CG, Johnson R, Lay JM, Lennon-Hopkins K, Saraceni-Richards C, Sciaky D, King BL, Rosenstein MC, Wiegers TC, Mattingly CJ., Nucleic Acids Res 41(database issue), 2013
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Toxicogenomic analysis of the particle dose- and size-response relationship of silica particles-induced toxicity in mice.
Lu X, Jin T, Jin Y, Wu L, Hu B, Tian Y, Fan X., Nanotechnology 24(1), 2013
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Lu X, Jin T, Jin Y, Wu L, Hu B, Tian Y, Fan X., Nanotechnology 24(1), 2013
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Proteomic and biochemical methods to study the cytoskeletome.
Klemke RL, Jiang X, Choi S, Kelber JA., Methods Mol Biol 1046(), 2013
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Klemke RL, Jiang X, Choi S, Kelber JA., Methods Mol Biol 1046(), 2013
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Wrangling phosphoproteomic data to elucidate cancer signaling pathways.
Grimes ML, Lee WJ, van der Maaten L, Shannon P., PLoS One 8(1), 2013
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Grimes ML, Lee WJ, van der Maaten L, Shannon P., PLoS One 8(1), 2013
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Post-translational events and modifications regulating plant enzymes involved in isoprenoid precursor biosynthesis.
Hemmerlin A., Plant Sci 203-204(), 2013
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Hemmerlin A., Plant Sci 203-204(), 2013
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Visualizing multidimensional cancer genomics data.
Schroeder MP, Gonzalez-Perez A, Lopez-Bigas N., Genome Med 5(1), 2013
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Schroeder MP, Gonzalez-Perez A, Lopez-Bigas N., Genome Med 5(1), 2013
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Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review.
Csermely P, Korcsmáros T, Kiss HJ, London G, Nussinov R., Pharmacol Ther 138(3), 2013
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Csermely P, Korcsmáros T, Kiss HJ, London G, Nussinov R., Pharmacol Ther 138(3), 2013
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Integrated analysis of transcriptomics and metabonomics profiles in aflatoxin B1-induced hepatotoxicity in rat.
Lu X, Hu B, Shao L, Tian Y, Jin T, Jin Y, Ji S, Fan X., Food Chem Toxicol 55(), 2013
PMID: 23385219
Lu X, Hu B, Shao L, Tian Y, Jin T, Jin Y, Ji S, Fan X., Food Chem Toxicol 55(), 2013
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Systems metabolic engineering in an industrial setting.
Sagt CM., Appl Microbiol Biotechnol 97(6), 2013
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Sagt CM., Appl Microbiol Biotechnol 97(6), 2013
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Network analysis for gene discovery in plant-specialized metabolism.
Higashi Y, Saito K., Plant Cell Environ 36(9), 2013
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Higashi Y, Saito K., Plant Cell Environ 36(9), 2013
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BiNoM 2.0, a Cytoscape plugin for accessing and analyzing pathways using standard systems biology formats.
Bonnet E, Calzone L, Rovera D, Stoll G, Barillot E, Zinovyev A., BMC Syst Biol 7(), 2013
PMID: 23453054
Bonnet E, Calzone L, Rovera D, Stoll G, Barillot E, Zinovyev A., BMC Syst Biol 7(), 2013
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Game on, science - how video game technology may help biologists tackle visualization challenges.
Lv Z, Tek A, Da Silva F, Empereur-mot C, Chavent M, Baaden M., PLoS One 8(3), 2013
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Lv Z, Tek A, Da Silva F, Empereur-mot C, Chavent M, Baaden M., PLoS One 8(3), 2013
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Label-free integrative pharmacology on-target of opioid ligands at the opioid receptor family.
Morse M, Sun H, Tran E, Levenson R, Fang Y., BMC Pharmacol Toxicol 14(), 2013
PMID: 23497702
Morse M, Sun H, Tran E, Levenson R, Fang Y., BMC Pharmacol Toxicol 14(), 2013
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Information engineering infrastructure for life sciences and its implementation in China.
Zhu W, Zhu Y, Yang X., Sci China Life Sci 56(3), 2013
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Zhu W, Zhu Y, Yang X., Sci China Life Sci 56(3), 2013
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High-sensitivity analytical approaches for the structural characterization of glycoproteins.
Alley WR, Mann BF, Novotny MV., Chem Rev 113(4), 2013
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Alley WR, Mann BF, Novotny MV., Chem Rev 113(4), 2013
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Pattern recognition in bioinformatics.
de Ridder D, de Ridder J, Reinders MJ., Brief Bioinform 14(5), 2013
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de Ridder D, de Ridder J, Reinders MJ., Brief Bioinform 14(5), 2013
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Systematic curation of protein and genetic interaction data for computable biology.
Dolinski K, Chatr-Aryamontri A, Tyers M., BMC Biol 11(), 2013
PMID: 23587305
Dolinski K, Chatr-Aryamontri A, Tyers M., BMC Biol 11(), 2013
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Proteomic analysis reveals differentially expressed proteins in macrophages infected with Leishmania amazonensis or Leishmania major.
Menezes JP, Almeida TF, Petersen AL, Guedes CE, Mota MS, Lima JG, Palma LC, Buck GA, Krieger MA, Probst CM, Veras PS., Microbes Infect 15(8-9), 2013
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Menezes JP, Almeida TF, Petersen AL, Guedes CE, Mota MS, Lima JG, Palma LC, Buck GA, Krieger MA, Probst CM, Veras PS., Microbes Infect 15(8-9), 2013
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Information content and scalability in signal transduction network reconstruction formats.
Rother M, Münzner U, Thieme S, Krantz M., Mol Biosyst 9(8), 2013
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Rother M, Münzner U, Thieme S, Krantz M., Mol Biosyst 9(8), 2013
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Automation of dimethylation after guanidination labeling chemistry and its compatibility with common buffers and surfactants for mass spectrometry-based shotgun quantitative proteome analysis.
Lo A, Tang Y, Chen L, Li L., Anal Chim Acta 788(), 2013
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Lo A, Tang Y, Chen L, Li L., Anal Chim Acta 788(), 2013
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NetGestalt: integrating multidimensional omics data over biological networks.
Shi Z, Wang J, Zhang B., Nat Methods 10(7), 2013
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Shi Z, Wang J, Zhang B., Nat Methods 10(7), 2013
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RCytoscape: tools for exploratory network analysis.
Shannon PT, Grimes M, Kutlu B, Bot JJ, Galas DJ., BMC Bioinformatics 14(), 2013
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Shannon PT, Grimes M, Kutlu B, Bot JJ, Galas DJ., BMC Bioinformatics 14(), 2013
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3Omics: a web-based systems biology tool for analysis, integration and visualization of human transcriptomic, proteomic and metabolomic data.
Kuo TC, Tian TF, Tseng YJ., BMC Syst Biol 7(), 2013
PMID: 23875761
Kuo TC, Tian TF, Tseng YJ., BMC Syst Biol 7(), 2013
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The KUPNetViz: a biological network viewer for multiple -omics datasets in kidney diseases.
Moulos P, Klein J, Jupp S, Stevens R, Bascands JL, Schanstra JP., BMC Bioinformatics 14(), 2013
PMID: 23883183
Moulos P, Klein J, Jupp S, Stevens R, Bascands JL, Schanstra JP., BMC Bioinformatics 14(), 2013
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Metabolomics, peptidomics and proteomics applications of capillary electrophoresis-mass spectrometry in Foodomics: a review.
Ibáñez C, Simó C, García-Cañas V, Cifuentes A, Castro-Puyana M., Anal Chim Acta 802(), 2013
PMID: 24176500
Ibáñez C, Simó C, García-Cañas V, Cifuentes A, Castro-Puyana M., Anal Chim Acta 802(), 2013
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GALANT: a Cytoscape plugin for visualizing data as functional landscapes projected onto biological networks.
Camilo E, Bovolenta LA, Acencio ML, Rybarczyk-Filho JL, Castro MA, Moreira JC, Lemke N., Bioinformatics 29(19), 2013
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Camilo E, Bovolenta LA, Acencio ML, Rybarczyk-Filho JL, Castro MA, Moreira JC, Lemke N., Bioinformatics 29(19), 2013
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Single-cell sequencing-based technologies will revolutionize whole-organism science.
Shapiro E, Biezuner T, Linnarsson S., Nat Rev Genet 14(9), 2013
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Shapiro E, Biezuner T, Linnarsson S., Nat Rev Genet 14(9), 2013
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Unraveling DNA damage response-signaling networks through systems approaches.
von Stechow L, van de Water B, Danen EH., Arch Toxicol 87(9), 2013
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von Stechow L, van de Water B, Danen EH., Arch Toxicol 87(9), 2013
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Use of single nucleotide polymorphism array technology to improve the identification of chromosomal lesions in leukemia.
Iacobucci I, Lonetti A, Papayannidis C, Martinelli G., Curr Cancer Drug Targets 13(7), 2013
PMID: 23941516
Iacobucci I, Lonetti A, Papayannidis C, Martinelli G., Curr Cancer Drug Targets 13(7), 2013
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Reprogramming in vivo produces teratomas and iPS cells with totipotency features.
Abad M, Mosteiro L, Pantoja C, Cañamero M, Rayon T, Ors I, Graña O, Megías D, Domínguez O, Martínez D, Manzanares M, Ortega S, Serrano M., Nature 502(7471), 2013
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Abad M, Mosteiro L, Pantoja C, Cañamero M, Rayon T, Ors I, Graña O, Megías D, Domínguez O, Martínez D, Manzanares M, Ortega S, Serrano M., Nature 502(7471), 2013
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Transcriptional landscapes of emerging autoimmunity: transient aberrations in the targeted tissue's extracellular milieu precede immune responses in Sjögren's syndrome.
Delaleu N, Nguyen CQ, Tekle KM, Jonsson R, Peck AB., Arthritis Res Ther 15(5), 2013
PMID: 24286337
Delaleu N, Nguyen CQ, Tekle KM, Jonsson R, Peck AB., Arthritis Res Ther 15(5), 2013
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enRoute: dynamic path extraction from biological pathway maps for exploring heterogeneous experimental datasets.
Partl C, Lex A, Streit M, Kalkofen D, Kashofer K, Schmalstieg D., BMC Bioinformatics 14 Suppl 19(), 2013
PMID: 24564375
Partl C, Lex A, Streit M, Kalkofen D, Kashofer K, Schmalstieg D., BMC Bioinformatics 14 Suppl 19(), 2013
PMID: 24564375
Transcriptome sequencing and microarray design for functional genomics in the extremophile Arabidopsis relative Thellungiella salsuginea (Eutrema salsugineum).
Lee YP, Giorgi FM, Lohse M, Kvederaviciute K, Klages S, Usadel B, Meskiene I, Reinhardt R, Hincha DK., BMC Genomics 14(), 2013
PMID: 24228715
Lee YP, Giorgi FM, Lohse M, Kvederaviciute K, Klages S, Usadel B, Meskiene I, Reinhardt R, Hincha DK., BMC Genomics 14(), 2013
PMID: 24228715
Entourage: visualizing relationships between biological pathways using contextual subsets.
Lex A, Partl C, Kalkofen D, Streit M, Gratzl S, Wassermann AM, Schmalstieg D, Pfister H., IEEE Trans Vis Comput Graph 19(12), 2013
PMID: 24051820
Lex A, Partl C, Kalkofen D, Streit M, Gratzl S, Wassermann AM, Schmalstieg D, Pfister H., IEEE Trans Vis Comput Graph 19(12), 2013
PMID: 24051820
Toward an integrated software platform for systems pharmacology.
Ghosh S, Matsuoka Y, Asai Y, Hsin KY, Kitano H., Biopharm Drug Dispos 34(9), 2013
PMID: 24150748
Ghosh S, Matsuoka Y, Asai Y, Hsin KY, Kitano H., Biopharm Drug Dispos 34(9), 2013
PMID: 24150748
POMO--Plotting Omics analysis results for Multiple Organisms.
Lin J, Kreisberg R, Kallio A, Dudley AM, Nykter M, Shmulevich I, May P, Autio R., BMC Genomics 14(), 2013
PMID: 24365393
Lin J, Kreisberg R, Kallio A, Dudley AM, Nykter M, Shmulevich I, May P, Autio R., BMC Genomics 14(), 2013
PMID: 24365393
Foodomics: MS-based strategies in modern food science and nutrition.
Herrero M, Simó C, García-Cañas V, Ibáñez E, Cifuentes A., Mass Spectrom Rev 31(1), 2012
PMID: 21374694
Herrero M, Simó C, García-Cañas V, Ibáñez E, Cifuentes A., Mass Spectrom Rev 31(1), 2012
PMID: 21374694
Pair-wise multicomparison and OPLS analyses of cold-acclimation phases in Siberian spruce.
Shiryaeva L, Antti H, Schröder WP, Strimbeck R, Shiriaev AS., Metabolomics 8(suppl 1), 2012
PMID: 22593724
Shiryaeva L, Antti H, Schröder WP, Strimbeck R, Shiriaev AS., Metabolomics 8(suppl 1), 2012
PMID: 22593724
Hive plots--rational approach to visualizing networks.
Krzywinski M, Birol I, Jones SJ, Marra MA., Brief Bioinform 13(5), 2012
PMID: 22155641
Krzywinski M, Birol I, Jones SJ, Marra MA., Brief Bioinform 13(5), 2012
PMID: 22155641
Mass spectrometry-based proteomics and network biology.
Bensimon A, Heck AJ, Aebersold R., Annu Rev Biochem 81(), 2012
PMID: 22439968
Bensimon A, Heck AJ, Aebersold R., Annu Rev Biochem 81(), 2012
PMID: 22439968
CHROMATRA: a Galaxy tool for visualizing genome-wide chromatin signatures.
Hentrich T, Schulze JM, Emberly E, Kobor MS., Bioinformatics 28(5), 2012
PMID: 22238257
Hentrich T, Schulze JM, Emberly E, Kobor MS., Bioinformatics 28(5), 2012
PMID: 22238257
To label or not to label: applications of quantitative proteomics in neuroscience research.
Filiou MD, Martins-de-Souza D, Guest PC, Bahn S, Turck CW., Proteomics 12(4-5), 2012
PMID: 22247077
Filiou MD, Martins-de-Souza D, Guest PC, Bahn S, Turck CW., Proteomics 12(4-5), 2012
PMID: 22247077
TranscriptomeBrowser 3.0: introducing a new compendium of molecular interactions and a new visualization tool for the study of gene regulatory networks.
Lepoivre C, Bergon A, Lopez F, Perumal NB, Nguyen C, Imbert J, Puthier D., BMC Bioinformatics 13(), 2012
PMID: 22292669
Lepoivre C, Bergon A, Lopez F, Perumal NB, Nguyen C, Imbert J, Puthier D., BMC Bioinformatics 13(), 2012
PMID: 22292669
Systems medicine and metabolic modelling.
Mardinoglu A, Nielsen J., J Intern Med 271(2), 2012
PMID: 22142312
Mardinoglu A, Nielsen J., J Intern Med 271(2), 2012
PMID: 22142312
Array-based cytogenetic approaches in acute myeloid leukemia: clinical impact and biological insights.
Bullinger L, Fröhling S., Semin Oncol 39(1), 2012
PMID: 22289490
Bullinger L, Fröhling S., Semin Oncol 39(1), 2012
PMID: 22289490
Creating interactive, web-based and data-enriched maps with the Systems Biology Graphical Notation.
Junker A, Rohn H, Czauderna T, Klukas C, Hartmann A, Schreiber F., Nat Protoc 7(3), 2012
PMID: 22383037
Junker A, Rohn H, Czauderna T, Klukas C, Hartmann A, Schreiber F., Nat Protoc 7(3), 2012
PMID: 22383037
Concordance of changes in metabolic pathways based on plasma metabolomics and skeletal muscle transcriptomics in type 1 diabetes.
Dutta T, Chai HS, Ward LE, Ghosh A, Persson XM, Ford GC, Kudva YC, Sun Z, Asmann YW, Kocher JP, Nair KS., Diabetes 61(5), 2012
PMID: 22415876
Dutta T, Chai HS, Ward LE, Ghosh A, Persson XM, Ford GC, Kudva YC, Sun Z, Asmann YW, Kocher JP, Nair KS., Diabetes 61(5), 2012
PMID: 22415876
A multilevel layout algorithm for visualizing physical and genetic interaction networks, with emphasis on their modular organization.
Tuikkala J, Vähämaa H, Salmela P, Nevalainen OS, Aittokallio T., BioData Min 5(), 2012
PMID: 22448851
Tuikkala J, Vähämaa H, Salmela P, Nevalainen OS, Aittokallio T., BioData Min 5(), 2012
PMID: 22448851
Visualization of the interactome: what are we looking at?
Fung DC, Li SS, Goel A, Hong SH, Wilkins MR., Proteomics 12(10), 2012
PMID: 22610544
Fung DC, Li SS, Goel A, Hong SH, Wilkins MR., Proteomics 12(10), 2012
PMID: 22610544
An eQTL biological data visualization challenge and approaches from the visualization community.
Bartlett CW, Cheong SY, Hou L, Paquette J, Lum PY, Jäger G, Battke F, Vehlow C, Heinrich J, Nieselt K, Sakai R, Aerts J, Ray WC., BMC Bioinformatics 13 Suppl 8(), 2012
PMID: 22607587
Bartlett CW, Cheong SY, Hou L, Paquette J, Lum PY, Jäger G, Battke F, Vehlow C, Heinrich J, Nieselt K, Sakai R, Aerts J, Ray WC., BMC Bioinformatics 13 Suppl 8(), 2012
PMID: 22607587
Model-driven design for the visual analysis of heterogeneous data.
Streit M, Schulz HJ, Lex A, Schmalstieg D, Schumann H., IEEE Trans Vis Comput Graph 18(6), 2012
PMID: 21690642
Streit M, Schulz HJ, Lex A, Schmalstieg D, Schumann H., IEEE Trans Vis Comput Graph 18(6), 2012
PMID: 21690642
Human amniotic epithelial cells are reprogrammed more efficiently by induced pluripotency than adult fibroblasts.
Easley CA, Miki T, Castro CA, Ozolek JA, Minervini CF, Ben-Yehudah A, Schatten GP., Cell Reprogram 14(3), 2012
PMID: 22686477
Easley CA, Miki T, Castro CA, Ozolek JA, Minervini CF, Ben-Yehudah A, Schatten GP., Cell Reprogram 14(3), 2012
PMID: 22686477
Application of approximate pattern matching in two dimensional spaces to grid layout for biochemical network maps.
Inoue K, Shimozono S, Yoshida H, Kurata H., PLoS One 7(6), 2012
PMID: 22679486
Inoue K, Shimozono S, Yoshida H, Kurata H., PLoS One 7(6), 2012
PMID: 22679486
Postgenomic approaches to using corynebacteria as biocatalysts.
Vertès AA, Inui M, Yukawa H., Annu Rev Microbiol 66(), 2012
PMID: 22803796
Vertès AA, Inui M, Yukawa H., Annu Rev Microbiol 66(), 2012
PMID: 22803796
High precision alignment of cryo-electron subtomograms through gradient-based parallel optimization.
Xu M, Alber F., BMC Syst Biol 6 Suppl 1(), 2012
PMID: 23046491
Xu M, Alber F., BMC Syst Biol 6 Suppl 1(), 2012
PMID: 23046491
atBioNet--an integrated network analysis tool for genomics and biomarker discovery.
Ding Y, Chen M, Liu Z, Ding D, Ye Y, Zhang M, Kelly R, Guo L, Su Z, Harris SC, Qian F, Ge W, Fang H, Xu X, Tong W., BMC Genomics 13(), 2012
PMID: 22817640
Ding Y, Chen M, Liu Z, Ding D, Ye Y, Zhang M, Kelly R, Guo L, Su Z, Harris SC, Qian F, Ge W, Fang H, Xu X, Tong W., BMC Genomics 13(), 2012
PMID: 22817640
Dynamic mass redistribution assay decodes differentiation of a neural progenitor stem cell.
Pai S, Verrier F, Sun H, Hu H, Ferrie AM, Eshraghi A, Fang Y., J Biomol Screen 17(9), 2012
PMID: 22885730
Pai S, Verrier F, Sun H, Hu H, Ferrie AM, Eshraghi A, Fang Y., J Biomol Screen 17(9), 2012
PMID: 22885730
Information visualization to enhance sensitivity and selectivity in biosensing.
Oliveira ON, Pavinatto FJ, Constantino CJ, Paulovich FV, de Oliveira MC., Biointerphases 7(1-4), 2012
PMID: 22911268
Oliveira ON, Pavinatto FJ, Constantino CJ, Paulovich FV, de Oliveira MC., Biointerphases 7(1-4), 2012
PMID: 22911268
Bioinformatics for cancer immunology and immunotherapy.
Charoentong P, Angelova M, Efremova M, Gallasch R, Hackl H, Galon J, Trajanoski Z., Cancer Immunol Immunother 61(11), 2012
PMID: 22986455
Charoentong P, Angelova M, Efremova M, Gallasch R, Hackl H, Galon J, Trajanoski Z., Cancer Immunol Immunother 61(11), 2012
PMID: 22986455
More than meets the eye. Modern experimental techniques require increasingly sophisticated approaches to data visualization.
Rinaldi A., EMBO Rep 13(10), 2012
PMID: 22986549
Rinaldi A., EMBO Rep 13(10), 2012
PMID: 22986549
Pathway-based visualization of cross-platform microarray datasets.
Wrzodek C, Eichner J, Zell A., Bioinformatics 28(23), 2012
PMID: 23047564
Wrzodek C, Eichner J, Zell A., Bioinformatics 28(23), 2012
PMID: 23047564
A global genome segmentation method for exploration of epigenetic patterns.
Steiner L, Hopp L, Wirth H, Galle J, Binder H, Prohaska SJ, Rohlf T., PLoS One 7(10), 2012
PMID: 23077526
Steiner L, Hopp L, Wirth H, Galle J, Binder H, Prohaska SJ, Rohlf T., PLoS One 7(10), 2012
PMID: 23077526
Validation of a robust proteomic analysis carried out on formalin-fixed paraffin-embedded tissues of the pancreas obtained from mouse and human.
Kojima K, Bowersock GJ, Kojima C, Klug CA, Grizzle WE, Mobley JA., Proteomics 12(22), 2012
PMID: 22997103
Kojima K, Bowersock GJ, Kojima C, Klug CA, Grizzle WE, Mobley JA., Proteomics 12(22), 2012
PMID: 22997103
VANTED v2: a framework for systems biology applications.
Rohn H, Junker A, Hartmann A, Grafahrend-Belau E, Treutler H, Klapperstück M, Czauderna T, Klukas C, Schreiber F., BMC Syst Biol 6(), 2012
PMID: 23140568
Rohn H, Junker A, Hartmann A, Grafahrend-Belau E, Treutler H, Klapperstück M, Czauderna T, Klukas C, Schreiber F., BMC Syst Biol 6(), 2012
PMID: 23140568
Visual analysis of transcriptome data in the context of anatomical structures and biological networks.
Junker A, Rohn H, Schreiber F., Front Plant Sci 3(), 2012
PMID: 23162564
Junker A, Rohn H, Schreiber F., Front Plant Sci 3(), 2012
PMID: 23162564
Integration of interactive, multi-scale network navigation approach with Cytoscape for functional genomics in the big data era.
Praneenararat T, Takagi T, Iwasaki W., BMC Genomics 13 Suppl 7(), 2012
PMID: 23281970
Praneenararat T, Takagi T, Iwasaki W., BMC Genomics 13 Suppl 7(), 2012
PMID: 23281970
Metabolomics of sepsis-induced acute lung injury: a new approach for biomarkers.
Lacy P., Am J Physiol Lung Cell Mol Physiol 300(1), 2011
PMID: 21056960
Lacy P., Am J Physiol Lung Cell Mol Physiol 300(1), 2011
PMID: 21056960
KaPPA-View4: a metabolic pathway database for representation and analysis of correlation networks of gene co-expression and metabolite co-accumulation and omics data.
Sakurai N, Ara T, Ogata Y, Sano R, Ohno T, Sugiyama K, Hiruta A, Yamazaki K, Yano K, Aoki K, Aharoni A, Hamada K, Yokoyama K, Kawamura S, Otsuka H, Tokimatsu T, Kanehisa M, Suzuki H, Saito K, Shibata D., Nucleic Acids Res 39(database issue), 2011
PMID: 21097783
Sakurai N, Ara T, Ogata Y, Sano R, Ohno T, Sugiyama K, Hiruta A, Yamazaki K, Yano K, Aoki K, Aharoni A, Hamada K, Yokoyama K, Kawamura S, Otsuka H, Tokimatsu T, Kanehisa M, Suzuki H, Saito K, Shibata D., Nucleic Acids Res 39(database issue), 2011
PMID: 21097783
The Protein Information and Property Explorer 2: gaggle-like exploration of biological proteomic data within one webpage.
Ramos H, Shannon P, Brusniak MY, Kusebauch U, Moritz RL, Aebersold R., Proteomics 11(1), 2011
PMID: 21182202
Ramos H, Shannon P, Brusniak MY, Kusebauch U, Moritz RL, Aebersold R., Proteomics 11(1), 2011
PMID: 21182202
Gradient-based high precision alignment of cryo-electron subtomograms.
Xu M, Alber F., IEEE Int Conf Systems Biol (), 2011
PMID: 25068871
Xu M, Alber F., IEEE Int Conf Systems Biol (), 2011
PMID: 25068871
ePlant and the 3D data display initiative: integrative systems biology on the world wide web.
Fucile G, Di Biase D, Nahal H, La G, Khodabandeh S, Chen Y, Easley K, Christendat D, Kelley L, Provart NJ., PLoS One 6(1), 2011
PMID: 21249219
Fucile G, Di Biase D, Nahal H, La G, Khodabandeh S, Chen Y, Easley K, Christendat D, Kelley L, Provart NJ., PLoS One 6(1), 2011
PMID: 21249219
Evolution and applications of plant pathway resources and databases.
Sucaet Y, Deva T., Brief Bioinform 12(5), 2011
PMID: 21949268
Sucaet Y, Deva T., Brief Bioinform 12(5), 2011
PMID: 21949268
Integration of lipidomics and transcriptomics data towards a systems biology model of sphingolipid metabolism.
Gupta S, Maurya MR, Merrill AH, Glass CK, Subramaniam S., BMC Syst Biol 5(), 2011
PMID: 21303545
Gupta S, Maurya MR, Merrill AH, Glass CK, Subramaniam S., BMC Syst Biol 5(), 2011
PMID: 21303545
Interactive, multiscale navigation of large and complicated biological networks.
Praneenararat T, Takagi T, Iwasaki W., Bioinformatics 27(8), 2011
PMID: 21349867
Praneenararat T, Takagi T, Iwasaki W., Bioinformatics 27(8), 2011
PMID: 21349867
A systems biological view of intracellular pathogens.
Beiting DP, Roos DS., Immunol Rev 240(1), 2011
PMID: 21349090
Beiting DP, Roos DS., Immunol Rev 240(1), 2011
PMID: 21349090
A cognitive task analysis of a visual analytic workflow: Exploring molecular interaction networks in systems biology.
Mirel B, Eichinger F, Keller BJ, Kretzler M., J Biomed Discov Collab 6(), 2011
PMID: 21455901
Mirel B, Eichinger F, Keller BJ, Kretzler M., J Biomed Discov Collab 6(), 2011
PMID: 21455901
Adaptive informatics for multifactorial and high-content biological data.
Millard BL, Niepel M, Menden MP, Muhlich JL, Sorger PK., Nat Methods 8(6), 2011
PMID: 21516115
Millard BL, Niepel M, Menden MP, Muhlich JL, Sorger PK., Nat Methods 8(6), 2011
PMID: 21516115
Systems biology approaches to heart development and congenital heart disease.
Sperling SR., Cardiovasc Res 91(2), 2011
PMID: 21527437
Sperling SR., Cardiovasc Res 91(2), 2011
PMID: 21527437
Update in acute lung injury and critical care 2010.
Vadász I, Sznajder JI., Am J Respir Crit Care Med 183(9), 2011
PMID: 21531954
Vadász I, Sznajder JI., Am J Respir Crit Care Med 183(9), 2011
PMID: 21531954
Signalogs: orthology-based identification of novel signaling pathway components in three metazoans.
Korcsmáros T, Szalay MS, Rovó P, Palotai R, Fazekas D, Lenti K, Farkas IJ, Csermely P, Vellai T., PLoS One 6(5), 2011
PMID: 21559328
Korcsmáros T, Szalay MS, Rovó P, Palotai R, Fazekas D, Lenti K, Farkas IJ, Csermely P, Vellai T., PLoS One 6(5), 2011
PMID: 21559328
Creating views on integrated multidomain data.
Rohn H, Klukas C, Schreiber F., Bioinformatics 27(13), 2011
PMID: 21551150
Rohn H, Klukas C, Schreiber F., Bioinformatics 27(13), 2011
PMID: 21551150
Evolutionary forces shaping the Golgi glycosylation machinery: why cell surface glycans are universal to living cells.
Varki A., Cold Spring Harb Perspect Biol 3(6), 2011
PMID: 21525513
Varki A., Cold Spring Harb Perspect Biol 3(6), 2011
PMID: 21525513
LinkinPath: from sequence to interconnected pathway.
Ingsriswang S, Yokwai S, Wichadakul D., Bioinformatics 27(14), 2011
PMID: 21636594
Ingsriswang S, Yokwai S, Wichadakul D., Bioinformatics 27(14), 2011
PMID: 21636594
MeRy-B: a web knowledgebase for the storage, visualization, analysis and annotation of plant NMR metabolomic profiles.
Ferry-Dumazet H, Gil L, Deborde C, Moing A, Bernillon S, Rolin D, Nikolski M, de Daruvar A, Jacob D., BMC Plant Biol 11(), 2011
PMID: 21668943
Ferry-Dumazet H, Gil L, Deborde C, Moing A, Bernillon S, Rolin D, Nikolski M, de Daruvar A, Jacob D., BMC Plant Biol 11(), 2011
PMID: 21668943
Detection of changes in gene regulatory patterns, elicited by perturbations of the Hsp90 molecular chaperone complex, by visualizing multiple experiments with an animation.
Echeverría PC, Forafonov F, Pandey DP, Mühlebach G, Picard D., BioData Min 4(1), 2011
PMID: 21672238
Echeverría PC, Forafonov F, Pandey DP, Mühlebach G, Picard D., BioData Min 4(1), 2011
PMID: 21672238
An intuitive graphical visualization technique for the interrogation of transcriptome data.
Bushati N, Smith J, Briscoe J, Watkins C., Nucleic Acids Res 39(17), 2011
PMID: 21690098
Bushati N, Smith J, Briscoe J, Watkins C., Nucleic Acids Res 39(17), 2011
PMID: 21690098
Intuitive visualization and analysis of multi-omics data and application to Escherichia coli carbon metabolism.
Enjalbert B, Jourdan F, Portais JC., PLoS One 6(6), 2011
PMID: 21731702
Enjalbert B, Jourdan F, Portais JC., PLoS One 6(6), 2011
PMID: 21731702
Visualizing meta-features in proteomic maps.
Giannopoulou EG, Lepouras G, Manolakos ES., BMC Bioinformatics 12(), 2011
PMID: 21798033
Giannopoulou EG, Lepouras G, Manolakos ES., BMC Bioinformatics 12(), 2011
PMID: 21798033
Integrating transcriptomics and metabonomics to unravel modes-of-action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in HepG2 cells.
Jennen D, Ruiz-Aracama A, Magkoufopoulou C, Peijnenburg A, Lommen A, van Delft J, Kleinjans J., BMC Syst Biol 5(), 2011
PMID: 21880148
Jennen D, Ruiz-Aracama A, Magkoufopoulou C, Peijnenburg A, Lommen A, van Delft J, Kleinjans J., BMC Syst Biol 5(), 2011
PMID: 21880148
Bioinformatics and systems biology of the lipidome.
Subramaniam S, Fahy E, Gupta S, Sud M, Byrnes RW, Cotter D, Dinasarapu AR, Maurya MR., Chem Rev 111(10), 2011
PMID: 21939287
Subramaniam S, Fahy E, Gupta S, Sud M, Byrnes RW, Cotter D, Dinasarapu AR, Maurya MR., Chem Rev 111(10), 2011
PMID: 21939287
Omics and integrated omics for the promotion of food and nutrition science.
Kato H, Takahashi S, Saito K., J Tradit Complement Med 1(1), 2011
PMID: 24716102
Kato H, Takahashi S, Saito K., J Tradit Complement Med 1(1), 2011
PMID: 24716102
MyBioNet: interactively visualize, edit and merge biological networks on the web.
Huang D, Huang Y, Bai Y, Chen D, Hofestädt R, Klukas C, Chen M., Bioinformatics 27(23), 2011
PMID: 21984760
Huang D, Huang Y, Bai Y, Chen D, Hofestädt R, Klukas C, Chen M., Bioinformatics 27(23), 2011
PMID: 21984760
Proteomics advances in the last decade: What is next?
Penque D, Simões T, Amado F., J Proteomics 75(1), 2011
PMID: 22061663
Penque D, Simões T, Amado F., J Proteomics 75(1), 2011
PMID: 22061663
Interactive, graph-based visual analysis of high-dimensional, multi-parameter fluorescence microscopy data in toponomics.
Oeltze S, Freiler W, Hillert R, Doleisch H, Preim B, Schubert W., IEEE Trans Vis Comput Graph 17(12), 2011
PMID: 22034305
Oeltze S, Freiler W, Hillert R, Doleisch H, Preim B, Schubert W., IEEE Trans Vis Comput Graph 17(12), 2011
PMID: 22034305
Comparative microbial modules resource: generation and visualization of multi-species biclusters.
Kacmarczyk T, Waltman P, Bate A, Eichenberger P, Bonneau R., PLoS Comput Biol 7(12), 2011
PMID: 22144874
Kacmarczyk T, Waltman P, Bate A, Eichenberger P, Bonneau R., PLoS Comput Biol 7(12), 2011
PMID: 22144874
Computational mass spectrometry-based proteomics.
Käll L, Vitek O., PLoS Comput Biol 7(12), 2011
PMID: 22144880
Käll L, Vitek O., PLoS Comput Biol 7(12), 2011
PMID: 22144880
Advances in omics and bioinformatics tools for systems analyses of plant functions.
Mochida K, Shinozaki K., Plant Cell Physiol 52(12), 2011
PMID: 22156726
Mochida K, Shinozaki K., Plant Cell Physiol 52(12), 2011
PMID: 22156726
Visualizing biological data-now and in the future.
O'Donoghue SI, Gavin AC, Gehlenborg N, Goodsell DS, Hériché JK, Nielsen CB, North C, Olson AJ, Procter JB, Shattuck DW, Walter T, Wong B., Nat Methods 7(3 suppl), 2010
PMID: 20195254
O'Donoghue SI, Gavin AC, Gehlenborg N, Goodsell DS, Hériché JK, Nielsen CB, North C, Olson AJ, Procter JB, Shattuck DW, Walter T, Wong B., Nat Methods 7(3 suppl), 2010
PMID: 20195254
Visualization of image data from cells to organisms.
Walter T, Shattuck DW, Baldock R, Bastin ME, Carpenter AE, Duce S, Ellenberg J, Fraser A, Hamilton N, Pieper S, Ragan MA, Schneider JE, Tomancak P, Hériché JK., Nat Methods 7(3 suppl), 2010
PMID: 20195255
Walter T, Shattuck DW, Baldock R, Bastin ME, Carpenter AE, Duce S, Ellenberg J, Fraser A, Hamilton N, Pieper S, Ragan MA, Schneider JE, Tomancak P, Hériché JK., Nat Methods 7(3 suppl), 2010
PMID: 20195255
Visualization of macromolecular structures.
O'Donoghue SI, Goodsell DS, Frangakis AS, Jossinet F, Laskowski RA, Nilges M, Saibil HR, Schafferhans A, Wade RC, Westhof E, Olson AJ., Nat Methods 7(3 suppl), 2010
PMID: 20195256
O'Donoghue SI, Goodsell DS, Frangakis AS, Jossinet F, Laskowski RA, Nilges M, Saibil HR, Schafferhans A, Wade RC, Westhof E, Olson AJ., Nat Methods 7(3 suppl), 2010
PMID: 20195256
Genome-wide approaches to schizophrenia.
Duan J, Sanders AR, Gejman PV., Brain Res Bull 83(3-4), 2010
PMID: 20433910
Duan J, Sanders AR, Gejman PV., Brain Res Bull 83(3-4), 2010
PMID: 20433910
Urinary proteomics evaluation in interstitial cystitis/painful bladder syndrome: a pilot study.
Goo YA, Tsai YS, Liu AY, Goodlett DR, Yang CC., Int Braz J Urol 36(4), 2010
PMID: 20815953
Goo YA, Tsai YS, Liu AY, Goodlett DR, Yang CC., Int Braz J Urol 36(4), 2010
PMID: 20815953
Systems biology of the gut: the interplay of food, microbiota and host at the mucosal interface.
Martins dos Santos V, Müller M, de Vos WM., Curr Opin Biotechnol 21(4), 2010
PMID: 20817507
Martins dos Santos V, Müller M, de Vos WM., Curr Opin Biotechnol 21(4), 2010
PMID: 20817507
Collective dynamics of specific gene ensembles crucial for neutrophil differentiation: the existence of genome vehicles revealed.
Tsuchiya M, Piras V, Giuliani A, Tomita M, Selvarajoo K., PLoS One 5(8), 2010
PMID: 20725638
Tsuchiya M, Piras V, Giuliani A, Tomita M, Selvarajoo K., PLoS One 5(8), 2010
PMID: 20725638
Finding the right questions: exploratory pathway analysis to enhance biological discovery in large datasets.
Kelder T, Conklin BR, Evelo CT, Pico AR., PLoS Biol 8(8), 2010
PMID: 20824171
Kelder T, Conklin BR, Evelo CT, Pico AR., PLoS Biol 8(8), 2010
PMID: 20824171
Root hair systems biology.
Libault M, Brechenmacher L, Cheng J, Xu D, Stacey G., Trends Plant Sci 15(11), 2010
PMID: 20851035
Libault M, Brechenmacher L, Cheng J, Xu D, Stacey G., Trends Plant Sci 15(11), 2010
PMID: 20851035
Practical application of toxicogenomics for profiling toxicant-induced biological perturbations.
Kiyosawa N, Manabe S, Yamoto T, Sanbuissho A., Int J Mol Sci 11(9), 2010
PMID: 20957103
Kiyosawa N, Manabe S, Yamoto T, Sanbuissho A., Int J Mol Sci 11(9), 2010
PMID: 20957103
Metabolic networks, microbial ecology and 'omics' technologies: towards understanding in situ biodegradation processes.
Vilchez-Vargas R, Junca H, Pieper DH., Environ Microbiol 12(12), 2010
PMID: 20860734
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Meyer M, Munzner T, DePace A, Pfister H., IEEE Trans Vis Comput Graph 16(6), 2010
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Prasad TS, Kandasamy K, Pandey A., Methods Mol. Biol. 577(), 2009
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von Mering C, Krause R, Snel B, Cornell M, Oliver SG, Fields S, Bork P., Nature 417(6887), 2002
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Bader GD, Hogue CW., BMC Bioinformatics 4(), 2003
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Kuhner S, van Noort V, Betts MJ, Leo-Macias A, Batisse C, Rode M, Yamada T, Maier T, Bader S, Beltran-Alvarez P, Castano-Diez D, Chen WH, Devos D, Guell M, Norambuena T, Racke I, Rybin V, Schmidt A, Yus E, Aebersold R, Herrmann R, Bottcher B, Frangakis AS, Russell RB, Serrano L, Bork P, Gavin AC., Science 326(5957), 2009
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Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, Ramage D, Amin N, Schwikowski B, Ideker T., Genome Res. 13(11), 2003
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Junker BH, Klukas C, Schreiber F., BMC Bioinformatics 7(), 2006
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Hu Z, Hung JH, Wang Y, Chang YC, Huang CL, Huyck M, DeLisi C., Nucleic Acids Res. 37(Web Server issue), 2009
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McGuffin MJ, Jurisica I., IEEE Trans Vis Comput Graph 15(6), 2009
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Hu Z, Mellor J, Wu J, Kanehisa M, Stuart JM, DeLisi C., Nat. Biotechnol. 25(5), 2007
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Barsky A, Munzner T, Gardy J, Kincaid R., IEEE Trans Vis Comput Graph 14(6), 2008
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de Lichtenberg U, Jensen LJ, Brunak S, Bork P., Science 307(5710), 2005
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Kanehisa M, Araki M, Goto S, Hattori M, Hirakawa M, Itoh M, Katayama T, Kawashima S, Okuda S, Tokimatsu T, Yamanishi Y., Nucleic Acids Res. 36(Database issue), 2007
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Matthews L, Gopinath G, Gillespie M, Caudy M, Croft D, de Bono B, Garapati P, Hemish J, Hermjakob H, Jassal B, Kanapin A, Lewis S, Mahajan S, May B, Schmidt E, Vastrik I, Wu G, Birney E, Stein L, D'Eustachio P., Nucleic Acids Res. 37(Database issue), 2008
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STITCH 2: an interaction network database for small molecules and proteins.
Kuhn M, Szklarczyk D, Franceschini A, Campillos M, von Mering C, Jensen LJ, Beyer A, Bork P., Nucleic Acids Res. 38(Database issue), 2009
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Quackenbush J., Nat. Rev. Genet. 2(6), 2001
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RNA-Seq: a revolutionary tool for transcriptomics.
Wang Z, Gerstein M, Snyder M., Nat. Rev. Genet. 10(1), 2009
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Quantitative mass spectrometry in proteomics: a critical review.
Bantscheff M, Schirle M, Sweetman G, Rick J, Kuster B., Anal Bioanal Chem 389(4), 2007
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Applying mass spectrometry-based proteomics to genetics, genomics and network biology.
Gstaiger M, Aebersold R., Nat. Rev. Genet. 10(9), 2009
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Freeman, PLOS Comput. Biol. 3(), 2007
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GenMAPP 2: new features and resources for pathway analysis.
Salomonis N, Hanspers K, Zambon AC, Vranizan K, Lawlor SC, Dahlquist KD, Doniger SW, Stuart J, Conklin BR, Pico AR., BMC Bioinformatics 8(), 2007
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Salomonis N, Hanspers K, Zambon AC, Vranizan K, Lawlor SC, Dahlquist KD, Doniger SW, Stuart J, Conklin BR, Pico AR., BMC Bioinformatics 8(), 2007
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Visualizing post genomics data-sets on customized pathway maps by ProMeTra-aeration-dependent gene expression and metabolism of Corynebacterium glutamicum as an example.
Neuweger H, Persicke M, Albaum SP, Bekel T, Dondrup M, Huser AT, Winnebald J, Schneider J, Kalinowski J, Goesmann A., BMC Syst Biol 3(), 2009
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Neuweger H, Persicke M, Albaum SP, Bekel T, Dondrup M, Huser AT, Winnebald J, Schneider J, Kalinowski J, Goesmann A., BMC Syst Biol 3(), 2009
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VistaClara: an expression browser plug-in for Cytoscape.
Kincaid R, Kuchinsky A, Creech M., Bioinformatics 24(18), 2008
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Kincaid R, Kuchinsky A, Creech M., Bioinformatics 24(18), 2008
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Coexpression analysis of human genes across many microarray data sets.
Lee HK, Hsu AK, Sajdak J, Qin J, Pavlidis P., Genome Res. 14(6), 2004
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Dunn, TrAC Trends Anal. Chem. 24(), 2005
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MAPMAN: a user-driven tool to display genomics data sets onto diagrams of metabolic pathways and other biological processes.
Thimm O, Blasing O, Gibon Y, Nagel A, Meyer S, Kruger P, Selbig J, Muller LA, Rhee SY, Stitt M., Plant J. 37(6), 2004
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The Pathway Tools cellular overview diagram and Omics Viewer.
Paley SM, Karp PD., Nucleic Acids Res. 34(13), 2006
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Tokimatsu T, Sakurai N, Suzuki H, Ohta H, Nishitani K, Koyama T, Umezawa T, Misawa N, Saito K, Shibata D., Plant Physiol. 138(3), 2005
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Tokimatsu T, Sakurai N, Suzuki H, Ohta H, Nishitani K, Koyama T, Umezawa T, Misawa N, Saito K, Shibata D., Plant Physiol. 138(3), 2005
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PathwayExplorer: web service for visualizing high-throughput expression data on biological pathways.
Mlecnik B, Scheideler M, Hackl H, Hartler J, Sanchez-Cabo F, Trajanoski Z., Nucleic Acids Res. 33(Web Server issue), 2005
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Mlecnik B, Scheideler M, Hackl H, Hartler J, Sanchez-Cabo F, Trajanoski Z., Nucleic Acids Res. 33(Web Server issue), 2005
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The MetaCyc Database of metabolic pathways and enzymes and the BioCyc collection of Pathway/Genome Databases.
Caspi R, Foerster H, Fulcher CA, Kaipa P, Krummenacker M, Latendresse M, Paley S, Rhee SY, Shearer AG, Tissier C, Walk TC, Zhang P, Karp PD., Nucleic Acids Res. 36(Database issue), 2007
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Caspi R, Foerster H, Fulcher CA, Kaipa P, Krummenacker M, Latendresse M, Paley S, Rhee SY, Shearer AG, Tissier C, Walk TC, Zhang P, Karp PD., Nucleic Acids Res. 36(Database issue), 2007
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Next generation simulation tools: the Systems Biology Workbench and BioSPICE integration.
Sauro HM, Hucka M, Finney A, Wellock C, Bolouri H, Doyle J, Kitano H., OMICS 7(4), 2003
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PATIKA: an integrated visual environment for collaborative construction and analysis of cellular pathways.
Demir E, Babur O, Dogrusoz U, Gursoy A, Nisanci G, Cetin-Atalay R, Ozturk M., Bioinformatics 18(7), 2002
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Demir E, Babur O, Dogrusoz U, Gursoy A, Nisanci G, Cetin-Atalay R, Ozturk M., Bioinformatics 18(7), 2002
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A generic algorithm for layout of biological networks.
Schreiber F, Dwyer T, Marriott K, Wybrow M., BMC Bioinformatics 10(), 2009
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Schreiber F, Dwyer T, Marriott K, Wybrow M., BMC Bioinformatics 10(), 2009
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An insight-based methodology for evaluating bioinformatics visualizations.
Saraiya P, North C, Duca K., IEEE Trans Vis Comput Graph 11(4), 2005
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Saraiya P, North C, Duca K., IEEE Trans Vis Comput Graph 11(4), 2005
PMID: 16138554
IPSEP-COLA: an incremental procedure for separation constraint layout of graphs.
Dwyer T, Koren Y, Marriott K., IEEE Trans Vis Comput Graph 12(5), 2006
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Dwyer T, Koren Y, Marriott K., IEEE Trans Vis Comput Graph 12(5), 2006
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Exploration of networks using overview+detail with constraint-based cooperative layout.
Dwyer T, Marriott K, Schreiber F, Stuckey P, Woodward M, Wybrow M., IEEE Trans Vis Comput Graph 14(6), 2008
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Dwyer T, Marriott K, Schreiber F, Stuckey P, Woodward M, Wybrow M., IEEE Trans Vis Comput Graph 14(6), 2008
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Viégas, IEEE Trans. Vis. Comput. Graph. 13(), 2007
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Heer, Inf. Vis. 7(), 2008
WikiPathways: pathway editing for the people.
Pico AR, Kelder T, van Iersel MP, Hanspers K, Conklin BR, Evelo C., PLoS Biol. 6(7), 2008
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Pico AR, Kelder T, van Iersel MP, Hanspers K, Conklin BR, Evelo C., PLoS Biol. 6(7), 2008
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Arena3D: visualization of biological networks in 3D.
Pavlopoulos GA, O'Donoghue SI, Satagopam VP, Soldatos TG, Pafilis E, Schneider R., BMC Syst Biol 2(), 2008
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Announcing the worldwide Protein Data Bank.
Berman H, Henrick K, Nakamura H., Nat. Struct. Biol. 10(12), 2003
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Berman H, Henrick K, Nakamura H., Nat. Struct. Biol. 10(12), 2003
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The HUPO PSI's molecular interaction format--a community standard for the representation of protein interaction data.
Hermjakob H, Montecchi-Palazzi L, Bader G, Wojcik J, Salwinski L, Ceol A, Moore S, Orchard S, Sarkans U, von Mering C, Roechert B, Poux S, Jung E, Mersch H, Kersey P, Lappe M, Li Y, Zeng R, Rana D, Nikolski M, Husi H, Brun C, Shanker K, Grant SG, Sander C, Bork P, Zhu W, Pandey A, Brazma A, Jacq B, Vidal M, Sherman D, Legrain P, Cesareni G, Xenarios I, Eisenberg D, Steipe B, Hogue C, Apweiler R., Nat. Biotechnol. 22(2), 2004
PMID: 14755292
Hermjakob H, Montecchi-Palazzi L, Bader G, Wojcik J, Salwinski L, Ceol A, Moore S, Orchard S, Sarkans U, von Mering C, Roechert B, Poux S, Jung E, Mersch H, Kersey P, Lappe M, Li Y, Zeng R, Rana D, Nikolski M, Husi H, Brun C, Shanker K, Grant SG, Sander C, Bork P, Zhu W, Pandey A, Brazma A, Jacq B, Vidal M, Sherman D, Legrain P, Cesareni G, Xenarios I, Eisenberg D, Steipe B, Hogue C, Apweiler R., Nat. Biotechnol. 22(2), 2004
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The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models.
Hucka M, Finney A, Sauro HM, Bolouri H, Doyle JC, Kitano H, Arkin AP, Bornstein BJ, Bray D, Cornish-Bowden A, Cuellar AA, Dronov S, Gilles ED, Ginkel M, Gor V, Goryanin II, Hedley WJ, Hodgman TC, Hofmeyr JH, Hunter PJ, Juty NS, Kasberger JL, Kremling A, Kummer U, Le Novere N, Loew LM, Lucio D, Mendes P, Minch E, Mjolsness ED, Nakayama Y, Nelson MR, Nielsen PF, Sakurada T, Schaff JC, Shapiro BE, Shimizu TS, Spence HD, Stelling J, Takahashi K, Tomita M, Wagner J, Wang J; SBML Forum., Bioinformatics 19(4), 2003
PMID: 12611808
Hucka M, Finney A, Sauro HM, Bolouri H, Doyle JC, Kitano H, Arkin AP, Bornstein BJ, Bray D, Cornish-Bowden A, Cuellar AA, Dronov S, Gilles ED, Ginkel M, Gor V, Goryanin II, Hedley WJ, Hodgman TC, Hofmeyr JH, Hunter PJ, Juty NS, Kasberger JL, Kremling A, Kummer U, Le Novere N, Loew LM, Lucio D, Mendes P, Minch E, Mjolsness ED, Nakayama Y, Nelson MR, Nielsen PF, Sakurada T, Schaff JC, Shapiro BE, Shimizu TS, Spence HD, Stelling J, Takahashi K, Tomita M, Wagner J, Wang J; SBML Forum., Bioinformatics 19(4), 2003
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CellML: its future, present and past.
Lloyd CM, Halstead MD, Nielsen PF., Prog. Biophys. Mol. Biol. 85(2-3), 2004
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Lloyd CM, Halstead MD, Nielsen PF., Prog. Biophys. Mol. Biol. 85(2-3), 2004
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The Systems Biology Graphical Notation.
Le Novere N, Hucka M, Mi H, Moodie S, Schreiber F, Sorokin A, Demir E, Wegner K, Aladjem MI, Wimalaratne SM, Bergman FT, Gauges R, Ghazal P, Kawaji H, Li L, Matsuoka Y, Villeger A, Boyd SE, Calzone L, Courtot M, Dogrusoz U, Freeman TC, Funahashi A, Ghosh S, Jouraku A, Kim S, Kolpakov F, Luna A, Sahle S, Schmidt E, Watterson S, Wu G, Goryanin I, Kell DB, Sander C, Sauro H, Snoep JL, Kohn K, Kitano H., Nat. Biotechnol. 27(8), 2009
PMID: 19668183
Le Novere N, Hucka M, Mi H, Moodie S, Schreiber F, Sorokin A, Demir E, Wegner K, Aladjem MI, Wimalaratne SM, Bergman FT, Gauges R, Ghazal P, Kawaji H, Li L, Matsuoka Y, Villeger A, Boyd SE, Calzone L, Courtot M, Dogrusoz U, Freeman TC, Funahashi A, Ghosh S, Jouraku A, Kim S, Kolpakov F, Luna A, Sahle S, Schmidt E, Watterson S, Wu G, Goryanin I, Kell DB, Sander C, Sauro H, Snoep JL, Kohn K, Kitano H., Nat. Biotechnol. 27(8), 2009
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Visualization of image data from cells to organisms.
Walter T, Shattuck DW, Baldock R, Bastin ME, Carpenter AE, Duce S, Ellenberg J, Fraser A, Hamilton N, Pieper S, Ragan MA, Schneider JE, Tomancak P, Heriche JK., Nat. Methods 7(3 Suppl), 2010
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Walter T, Shattuck DW, Baldock R, Bastin ME, Carpenter AE, Duce S, Ellenberg J, Fraser A, Hamilton N, Pieper S, Ragan MA, Schneider JE, Tomancak P, Heriche JK., Nat. Methods 7(3 Suppl), 2010
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Visualization of macromolecular structures.
O'Donoghue SI, Goodsell DS, Frangakis AS, Jossinet F, Laskowski RA, Nilges M, Saibil HR, Schafferhans A, Wade RC, Westhof E, Olson AJ., Nat. Methods 7(3 Suppl), 2010
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O'Donoghue SI, Goodsell DS, Frangakis AS, Jossinet F, Laskowski RA, Nilges M, Saibil HR, Schafferhans A, Wade RC, Westhof E, Olson AJ., Nat. Methods 7(3 Suppl), 2010
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Visualizing genomes: techniques and challenges.
Nielsen CB, Cantor M, Dubchak I, Gordon D, Wang T., Nat. Methods 7(3 Suppl), 2010
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