Reduced expression of transforming growth factor ß1 exacerbates pathology in an experimental asthma model

Scherf W, Burdach S, Hansen G (2005)
Eur.J.Immunol 35(1): 198-206.

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DOI
Autor*in
Scherf, WiebkeUniBi; Burdach, S.; Hansen, G.
Einrichtung
Fakultät für Biologie > Biologiedidaktik (Botanik und Zellbiologie)
Erscheinungsjahr
2005
Zeitschriftentitel
Eur.J.Immunol
Band
35
Ausgabe
1
Seite(n)
198-206
ISSN
0014-2980
eISSN
1521-4141
Page URI
https://pub.uni-bielefeld.de/record/1866879

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Scherf W, Burdach S, Hansen G. Reduced expression of transforming growth factor ß1 exacerbates pathology in an experimental asthma model. Eur.J.Immunol. 2005;35(1):198-206.
Scherf, W., Burdach, S., & Hansen, G. (2005). Reduced expression of transforming growth factor ß1 exacerbates pathology in an experimental asthma model. Eur.J.Immunol, 35(1), 198-206. https://doi.org/10.1002/eji.200425209
Scherf, Wiebke, Burdach, S., and Hansen, G. 2005. “Reduced expression of transforming growth factor ß1 exacerbates pathology in an experimental asthma model”. Eur.J.Immunol 35 (1): 198-206.
Scherf, W., Burdach, S., and Hansen, G. (2005). Reduced expression of transforming growth factor ß1 exacerbates pathology in an experimental asthma model. Eur.J.Immunol 35, 198-206.
Scherf, W., Burdach, S., & Hansen, G., 2005. Reduced expression of transforming growth factor ß1 exacerbates pathology in an experimental asthma model. Eur.J.Immunol, 35(1), p 198-206.
W. Scherf, S. Burdach, and G. Hansen, “Reduced expression of transforming growth factor ß1 exacerbates pathology in an experimental asthma model”, Eur.J.Immunol, vol. 35, 2005, pp. 198-206.
Scherf, W., Burdach, S., Hansen, G.: Reduced expression of transforming growth factor ß1 exacerbates pathology in an experimental asthma model. Eur.J.Immunol. 35, 198-206 (2005).
Scherf, Wiebke, Burdach, S., and Hansen, G. “Reduced expression of transforming growth factor ß1 exacerbates pathology in an experimental asthma model”. Eur.J.Immunol 35.1 (2005): 198-206.

43 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Proteomic and transcriptomic analysis of lung tissue in OVA-challenged mice.
Lee Y, Hwang YH, Kim KJ, Park AK, Paik MJ, Kim SH, Lee SU, Yee ST, Son YJ., Arch Pharm Res 41(1), 2018
PMID: 29086354
TGFβ as a therapeutic target in cystic fibrosis.
Kramer EL, Clancy JP., Expert Opin Ther Targets 22(2), 2018
PMID: 29168406
Petiveria alliacea Suppresses Airway Inflammation and Allergen-Specific Th2 Responses in Ovalbumin-Sensitized Murine Model of Asthma.
Rosa MPG, Jose MMF., Chin J Integr Med 24(12), 2018
PMID: 30341485
Effect of polymorphisms on TGFB1 on allergic asthma and helminth infection in an African admixed population.
Costa RD, Figueiredo CA, Barreto ML, Alcantara-Neves NM, Rodrigues LC, Cruz AA, Vergara C, Rafaels N, Foster C, Potee J, Campbell M, Mathias RA, Barnes KC., Ann Allergy Asthma Immunol 118(4), 2017
PMID: 28284979
Transforming Growth Factor β1 Function in Airway Remodeling and Hyperresponsiveness. The Missing Link?
Ojiaku CA, Yoo EJ, Panettieri RA., Am J Respir Cell Mol Biol 56(4), 2017
PMID: 27854509
Immunization against TGF-β1 reduces collagen deposition but increases sustained inflammation in a murine asthma model.
Ma Y, Huang W, Liu C, Li Y, Xia Y, Yang X, Sun W, Bai H, Li Q, Peng Z., Hum Vaccin Immunother 12(7), 2016
PMID: 26901684
Transforming Growth Factor-β: Master Regulator of the Respiratory System in Health and Disease.
Aschner Y, Downey GP., Am J Respir Cell Mol Biol 54(5), 2016
PMID: 26796672
Ketamine Inhalation Ameliorates Ovalbumin-Induced Murine Asthma by Suppressing the Epithelial-Mesenchymal Transition.
Song L, Sen S, Sun Y, Zhou J, Mo L, He Y., Med Sci Monit 22(), 2016
PMID: 27418244
Effects of Laminaria japonica polysaccharides on airway inflammation of lungs in an asthma mouse model.
Lin R, Liu X, Meng Y, Xu M, Guo J., Multidiscip Respir Med 10(1), 2015
PMID: 26110056
Obesity- and aging-induced excess of central transforming growth factor-β potentiates diabetic development via an RNA stress response.
Yan J, Zhang H, Yin Y, Li J, Tang Y, Purkayastha S, Li L, Cai D., Nat Med 20(9), 2014
PMID: 25086906
Foxp3(+)-Treg cells enhanced by repeated low-dose gamma-irradiation attenuate ovalbumin-induced allergic asthma in mice.
Park BS, Hong GU, Ro JY., Radiat Res 179(5), 2013
PMID: 23560633
A protective role for periostin and TGF-β in IgE-mediated allergy and airway hyperresponsiveness.
Gordon ED, Sidhu SS, Wang ZE, Woodruff PG, Yuan S, Solon MC, Conway SJ, Huang X, Locksley RM, Fahy JV., Clin Exp Allergy 42(1), 2012
PMID: 22093101
MAPK regulation of IL-4/IL-13 receptors contributes to the synergistic increase in CCL11/eotaxin-1 in response to TGF-β1 and IL-13 in human airway fibroblasts.
Zhou X, Hu H, Balzar S, Trudeau JB, Wenzel SE., J Immunol 188(12), 2012
PMID: 22573806
Transforming growth factor-beta1 in inflammatory airway disease: a key for understanding inflammation and remodeling.
Yang YC, Zhang N, Van Crombruggen K, Hu GH, Hong SL, Bachert C., Allergy 67(10), 2012
PMID: 22913656
Regulatory T cells and the control of the allergic response.
Agua-Doce A, Graca L., J Allergy (Cairo) 2012(), 2012
PMID: 23056063
Protein tyrosine phosphatase SHP2 regulates TGF-β1 production in airway epithelia and asthmatic airway remodeling in mice.
Qin XJ, Zhang GS, Zhang X, Qiu ZW, Wang PL, Li YW, Li W, Xie QM, Ke YH, Lee JJ, Shen HH., Allergy 67(12), 2012
PMID: 23057634
Epistatic interactions between Tgfb1 and genetic loci, Tgfbm2 and Tgfbm3, determine susceptibility to an asthmatic stimulus.
Freimuth J, Clermont FF, Huang X, DeSapio A, Tokuyasu TA, Sheppard D, Akhurst RJ., Proc Natl Acad Sci U S A 109(44), 2012
PMID: 23064636
Chronic inflammation and asthma.
Murdoch JR, Lloyd CM., Mutat Res 690(1-2), 2010
PMID: 19769993
Tgf-Beta isoform specific regulation of airway inflammation and remodelling in a murine model of asthma.
Bottoms SE, Howell JE, Reinhardt AK, Evans IC, McAnulty RJ., PLoS One 5(3), 2010
PMID: 20300191
Structured regulation of inflammation during respiratory viral infection.
Hussell T, Goulding J., Lancet Infect Dis 10(5), 2010
PMID: 20417418
Association between genetic variations of the transforming growth factor ß receptor type III and asthma in a Korean population.
Kim HK, Jang TW, Jung MH, Park HW, Lee JE, Shin ES, Cho SH, Min KU, Kim YY., Exp Mol Med 42(6), 2010
PMID: 20386084
Th2 cells as targets for therapeutic intervention in allergic bronchial asthma.
Wegmann M., Expert Rev Mol Diagn 9(1), 2009
PMID: 19099351
Different inflammatory mechanisms in lungs of severe and mild asthma: crosstalk of NF-kappa-B, TGFbeta1, Bax, Bcl-2, IL-4 and IgE.
Abdulamir AS, Hafidh RR, Abubakar F., Scand J Clin Lab Invest 69(4), 2009
PMID: 19347746
Regulatory T cells in bronchial asthma.
Ryanna K, Stratigou V, Safinia N, Hawrylowicz C., Allergy 64(3), 2009
PMID: 19220222
TGF-beta can leave you breathless.
Qian BF, Wahl SM., Curr Opin Pharmacol 9(4), 2009
PMID: 19467929
Regulatory T cells in asthma.
Lloyd CM, Hawrylowicz CM., Immunity 31(3), 2009
PMID: 19766086
TGFB1 promoter polymorphism C-509T and pathophysiology of asthma.
Ueda T, Niimi A, Matsumoto H, Takemura M, Yamaguchi M, Matsuoka H, Jinnai M, Chin K, Minakuchi M, Cheng L, Shirakawa T, Mishima M., J Allergy Clin Immunol 121(3), 2008
PMID: 18036644
Potential health effects from non-specific stimulation of the immune function in early age: the example of BCG vaccination.
Rousseau MC, Parent ME, St-Pierre Y., Pediatr Allergy Immunol 19(5), 2008
PMID: 18167158
Transforming growth factor-beta regulates house dust mite-induced allergic airway inflammation but not airway remodeling.
Fattouh R, Midence NG, Arias K, Johnson JR, Walker TD, Goncharova S, Souza KP, Gregory RC, Lonning S, Gauldie J, Jordana M., Am J Respir Crit Care Med 177(6), 2008
PMID: 18174546
Chronic inflammation in asthma: a contest of persistence vs resolution.
Van Hove CL, Maes T, Joos GF, Tournoy KG., Allergy 63(9), 2008
PMID: 18616676
The effect of 4 weeks treatment with desloratadine (5mg daily) on levels of interleukin (IL)-4, IL-10, IL-18 and TGF beta in patients suffering from seasonal allergic rhinitis.
Tworek D, Bocheńska-Marciniak M, Kupczyk M, Górski P, Kuna P., Pulm Pharmacol Ther 20(3), 2007
PMID: 16530440
The chemokine receptor D6 has opposing effects on allergic inflammation and airway reactivity.
Whitehead GS, Wang T, DeGraff LM, Card JW, Lira SA, Graham GJ, Cook DN., Am J Respir Crit Care Med 175(3), 2007
PMID: 17095748
Comparison of airway remodeling in acute, subacute, and chronic models of allergic airways disease.
Locke NR, Royce SG, Wainewright JS, Samuel CS, Tang ML., Am J Respir Cell Mol Biol 36(5), 2007
PMID: 17237192
Examining potential therapies targeting myocardial fibrosis through the inhibition of transforming growth factor-beta 1.
Khan R., Cardiology 108(4), 2007
PMID: 17308385
Transforming growth factor-beta1 suppresses airway hyperresponsiveness in allergic airway disease.
Alcorn JF, Rinaldi LM, Jaffe EF, van Loon M, Bates JH, Janssen-Heininger YM, Irvin CG., Am J Respir Crit Care Med 176(10), 2007
PMID: 17761617
The involvement of type 1a angiotensin II receptors in the regulation of airway inflammation in a murine model of allergic asthma.
Ohwada K, Watanabe K, Okuyama K, Ohkawara Y, Sugaya T, Takayanagi M, Ohno I., Clin Exp Allergy 37(11), 2007
PMID: 17877756
Controversy surrounding the increased expression of TGF beta 1 in asthma.
Bossé Y, Rola-Pleszczynski M., Respir Res 8(), 2007
PMID: 17892594
Smad3 -signalling and Th2 cytokines in normal mouse airways and in a mouse model of asthma.
Anthoni M, Wang G, Leino MS, Lauerma AI, Alenius HT, Wolff HJ., Int J Biol Sci 3(7), 2007
PMID: 18071588
Targeting memory Th2 cells for the treatment of allergic asthma.
Epstein MM., Pharmacol Ther 109(1-2), 2006
PMID: 16081161
Transforming growth factor-beta regulation of immune responses.
Li MO, Wan YY, Sanjabi S, Robertson AK, Flavell RA., Annu Rev Immunol 24(), 2006
PMID: 16551245
Fibrosis in heart disease: understanding the role of transforming growth factor-beta in cardiomyopathy, valvular disease and arrhythmia.
Khan R, Sheppard R., Immunology 118(1), 2006
PMID: 16630019
[Eosinophilic inflammation in bronchial asthma: its re-evaluation].
Fujisawa T., Nihon Naika Gakkai Zasshi 95(8), 2006
PMID: 16955945
T regulatory cells in allergen-specific immunotherapy.
Verhagen J, Taylor A, Blaser K, Akdis M, Akdis CA., Int Rev Immunol 24(5-6), 2005
PMID: 16318994

56 References

Daten bereitgestellt von Europe PubMed Central.

Asthma: an epidemic of dysregulated immunity.
Umetsu DT, McIntire JJ, Akbari O, Macaubas C, DeKruyff RH., Nat. Immunol. 3(8), 2002
PMID: 12145657
Vaccination with heat-killed Listeria as adjuvant reverses established allergen-induced airway hyperreactivity and inflammation: role of CD8+ T cells and IL-18.
Hansen G, Yeung VP, Berry G, Umetsu DT, DeKruyff RH., J. Immunol. 164(1), 2000
PMID: 10605015
Vaccination with allergen-IL-18 fusion DNA protects against, and reverses established, airway hyperreactivity in a murine asthma model.
Maecker HT, Hansen G, Walter DM, DeKruyff RH, Levy S, Umetsu DT., J. Immunol. 166(2), 2001
PMID: 11145673
Novel vaccines protecting against the development of allergic disorders: a double-edged sword?
Erb KJ, Wohlleben G., Curr. Opin. Immunol. 14(5), 2002
PMID: 12183166
T-cell cytokine profile evaluated at the single cell level in BAL and blood in allergic asthma.
Krug N, Madden J, Redington AE, Lackie P, Djukanovic R, Schauer U, Holgate ST, Frew AJ, Howarth PH., Am. J. Respir. Cell Mol. Biol. 14(4), 1996
PMID: 8600935
Effects of recombinant human interleukin-12 on eosinophils, airway hyper-responsiveness, and the late asthmatic response.
Bryan SA, O'Connor BJ, Matti S, Leckie MJ, Kanabar V, Khan J, Warrington SJ, Renzetti L, Rames A, Bock JA, Boyce MJ, Hansel TT, Holgate ST, Barnes PJ., Lancet 356(9248), 2000
PMID: 11191543
Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation.
Hansen G, Berry G, DeKruyff RH, Umetsu DT., J. Clin. Invest. 103(2), 1999
PMID: 9916129
Transforming growth factor beta is an important immunomodulatory protein for human B lymphocytes.
Kehrl JH, Roberts AB, Wakefield LM, Jakowlew S, Sporn MB, Fauci AS., J. Immunol. 137(12), 1986
PMID: 2878044
Transforming growth factor-beta is a potent immunosuppressive agent that inhibits IL-1-dependent lymphocyte proliferation.
Wahl SM, Hunt DA, Wong HL, Dougherty S, McCartney-Francis N, Wahl LM, Ellingsworth L, Schmidt JA, Hall G, Roberts AB., J. Immunol. 140(9), 1988
PMID: 3129508
Inhibition of cytokine production by cyclosporin A and transforming growth factor beta.
Espevik T, Figari IS, Shalaby MR, Lackides GA, Lewis GD, Shepard HM, Palladino MA Jr., J. Exp. Med. 166(2), 1987
PMID: 3110354
Transforming growth factor-beta in leishmanial infection: a parasite escape mechanism.
Barral-Netto M, Barral A, Brownell CE, Skeiky YA, Ellingsworth LR, Twardzik DR, Reed SG., Science 257(5069), 1992
PMID: 1636092
Transforming growth factor beta 1 suppresses acute and chronic arthritis in experimental animals.
Brandes ME, Allen JB, Ogawa Y, Wahl SM., J. Clin. Invest. 87(3), 1991
PMID: 1999490
Protective effect of transforming growth factor beta 1 on experimental autoimmune diseases in mice.
Kuruvilla AP, Shah R, Hochwald GM, Liggitt HD, Palladino MA, Thorbecke GJ., Proc. Natl. Acad. Sci. U.S.A. 88(7), 1991
PMID: 2011600
Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease.
Shull MM, Ormsby I, Kier AB, Pawlowski S, Diebold RJ, Yin M, Allen R, Sidman C, Proetzel G, Calvin D., Nature 359(6397), 1992
PMID: 1436033
Transforming growth factor-beta 1 knockout mice. A mutation in one cytokine gene causes a dramatic inflammatory disease.
Kulkarni AB, Karlsson S., Am. J. Pathol. 143(1), 1993
PMID: 8317552
Gastric lesions in transforming growth factor beta-1 heterozygous mice.
Boivin GP, Molina JR, Ormsby I, Stemmermann G, Doetschman T., Lab. Invest. 74(2), 1996
PMID: 8780168
CD4(+) T helper cells engineered to produce latent TGF-beta1 reverse allergen-induced airway hyperreactivity and inflammation.
Hansen G, McIntire JJ, Yeung VP, Berry G, Thorbecke GJ, Chen L, DeKruyff RH, Umetsu DT., J. Clin. Invest. 105(1), 2000
PMID: 10619862
Transforming growth factor-beta 1 in asthma. Measurement in bronchoalveolar lavage fluid.
Redington AE, Madden J, Frew AJ, Djukanovic R, Roche WR, Holgate ST, Howarth PH., Am. J. Respir. Crit. Care Med. 156(2 Pt 1), 1997
PMID: 9279252
Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency.
Tang B, Bottinger EP, Jakowlew SB, Bagnall KM, Mariano J, Anver MR, Letterio JJ, Wakefield LM., Nat. Med. 4(7), 1998
PMID: 9662371
Transforming growth factor-beta in T-cell biology.
Gorelik L, Flavell RA., Nat. Rev. Immunol. 2(1), 2002
PMID: 11905837
Treatment of experimental (Trinitrobenzene sulfonic acid) colitis by intranasal administration of transforming growth factor (TGF)-beta1 plasmid: TGF-beta1-mediated suppression of T helper cell type 1 response occurs by interleukin (IL)-10 induction and IL-12 receptor beta2 chain downregulation.
Kitani A, Fuss IJ, Nakamura K, Schwartz OM, Usui T, Strober W., J. Exp. Med. 192(1), 2000
PMID: 10880525
Physical and functional interaction between GATA-3 and Smad3 allows TGF-beta regulation of GATA target genes.
Blokzijl A, ten Dijke P, Ibanez CF., Curr. Biol. 12(1), 2002
PMID: 11790301
Regulation of mucosal immune responses by recombinant interleukin 10 produced by intestinal epithelial cells in mice.
De Winter H, Elewaut D, Turovskaya O, Huflejt M, Shimeld C, Hagenbaugh A, Binder S, Takahashi I, Kronenberg M, Cheroutre H., Gastroenterology 122(7), 2002
PMID: 12055591
Factors involved in the differentiation of TGF-beta-producing cells from naive CD4+ T cells: IL-4 and IFN-gamma have opposing effects, while TGF-beta positively regulates its own production.
Seder RA, Marth T, Sieve MC, Strober W, Letterio JJ, Roberts AB, Kelsall B., J. Immunol. 160(12), 1998
PMID: 9637480
TGF-beta regulates airway responses via T cells.
Schramm C, Herz U, Podlech J, Protschka M, Finotto S, Reddehase MJ, Kohler H, Galle PR, Lohse AW, Blessing M., J. Immunol. 170(3), 2003
PMID: 12538691
Transforming growth factor-beta expression in mucosal biopsies in asthma and chronic bronchitis.
Vignola AM, Chanez P, Chiappara G, Merendino A, Pace E, Rizzo A, la Rocca AM, Bellia V, Bonsignore G, Bousquet J., Am. J. Respir. Crit. Care Med. 156(2 Pt 1), 1997
PMID: 9279245
Eosinophil-associated TGF-beta1 mRNA expression and airways fibrosis in bronchial asthma.
Minshall EM, Leung DY, Martin RJ, Song YL, Cameron L, Ernst P, Hamid Q., Am. J. Respir. Cell Mol. Biol. 17(3), 1997
PMID: 9308919
Peripheral blood and airway tissue expression of transforming growth factor beta by neutrophils in asthmatic subjects and normal control subjects.
Chu HW, Trudeau JB, Balzar S, Wenzel SE., J. Allergy Clin. Immunol. 106(6), 2000
PMID: 11112895
Transforming growth factor-beta as a regulator of site-specific T-cell inflammatory response.
Ludviksson BR, Gunnlaugsdottir B., Scand. J. Immunol. 58(2), 2003
PMID: 12869133
The role of transforming growth factor beta in lung development and disease.
Bartram U, Speer CP., Chest 125(2), 2004
PMID: 14769761
Regulation of immune responses by TGF-beta.
Letterio JJ, Roberts AB., Annu. Rev. Immunol. 16(), 1998
PMID: 9597127
Diverse cellular TGF-beta 1 and TGF-beta 3 gene expression in normal human and murine lung.
Coker RK, Laurent GJ, Shahzeidi S, Hernandez-Rodriguez NA, Pantelidis P, du Bois RM, Jeffery PK, McAnulty RJ., Eur. Respir. J. 9(12), 1996
PMID: 8980960
Expression of transforming growth factor-beta 1, -beta 2, and -beta 3 mRNA and protein in the murine lung.
Pelton RW, Johnson MD, Perkett EA, Gold LI, Moses HL., Am. J. Respir. Cell Mol. Biol. 5(6), 1991
PMID: 1958379
Transforming growth factor beta in normal human lung: preferential location in bronchial epithelial cells.
Magnan A, Frachon I, Rain B, Peuchmaur M, Monti G, Lenot B, Fattal M, Simonneau G, Galanaud P, Emilie D., Thorax 49(8), 1994
PMID: 8091325
Transforming growth factor beta1 and recruitment of macrophages and mast cells in airways in chronic obstructive pulmonary disease.
de Boer WI, van Schadewijk A, Sont JK, Sharma HS, Stolk J, Hiemstra PS, van Krieken JH., Am. J. Respir. Crit. Care Med. 158(6), 1998
PMID: 9847291
TGF-beta 1, but not TGF-beta 2 or TGF-beta 3, is differentially present in epithelial cells of advanced pulmonary fibrosis: an immunohistochemical study.
Khalil N, O'Connor RN, Flanders KC, Unruh H., Am. J. Respir. Cell Mol. Biol. 14(2), 1996
PMID: 8630262
Immunohistochemical localization of transforming growth factor beta isoforms in asbestos-related diseases.
Jagirdar J, Lee TC, Reibman J, Gold LI, Aston C, Begin R, Rom WN., Environ. Health Perspect. 105 Suppl 5(), 1997
PMID: 9400723
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production.
Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, Zhang Y, Elias JA., J. Clin. Invest. 103(6), 1999
PMID: 10079098
Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity.
Rankin JA, Picarella DE, Geba GP, Temann UA, Prasad B, DiCosmo B, Tarallo A, Stripp B, Whitsett J, Flavell RA., Proc. Natl. Acad. Sci. U.S.A. 93(15), 1996
PMID: 8755560
Allergen-induced IL-9 directly stimulates mucin transcription in respiratory epithelial cells.
Longphre M, Li D, Gallup M, Drori E, Ordonez CL, Redman T, Wenzel S, Bice DE, Fahy JV, Basbaum C., J. Clin. Invest. 104(10), 1999
PMID: 10562299
Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma.
Lee JJ, McGarry MP, Farmer SC, Denzler KL, Larson KA, Carrigan PE, Brenneise IE, Horton MA, Haczku A, Gelfand EW, Leikauf GD, Lee NA., J. Exp. Med. 185(12), 1997
PMID: 9182686
Requirement for IL-13 independently of IL-4 in experimental asthma.
Grunig G, Warnock M, Wakil AE, Venkayya R, Brombacher F, Rennick DM, Sheppard D, Mohrs M, Donaldson DD, Locksley RM, Corry DB., Science 282(5397), 1998
PMID: 9856950
Essential role of Id2 in negative regulation of IgE class switching.
Sugai M, Gonda H, Kusunoki T, Katakai T, Yokota Y, Shimizu A., Nat. Immunol. 4(1), 2002
PMID: 12483209
Immune sources of transforming growth factor-beta1 reduce transplant arteriosclerosis: insight derived from a knockout mouse model.
Koglin J, Glysing-Jensen T, Raisanen-Sokolowski A, Russell ME., Circ. Res. 83(6), 1998
PMID: 9742061
Enhanced tumorigenesis and reduced transforming growth factor-beta type II receptor in lung tumors from mice with reduced gene dosage of transforming growth factor-beta1.
Kang Y, Mariano JM, Angdisen J, Moody TW, Diwan BA, Wakefield LM, Jakowlew SB., Mol. Carcinog. 29(2), 2000
PMID: 11074608
Heterozygous inactivation of TGF-beta1 increases the susceptibility to chemically induced mouse lung tumorigenesis independently of mutational activation of K-ras.
McKenna IM, Ramakrishna G, Diwan BA, Kang Y, Shiao YH, Wakefield LM, Powell DA, Anderson LM, Jakowlew SB., Toxicol. Lett. 123(2-3), 2001
PMID: 11641043
Altered expression of G1/S regulatory genes occurs early and frequently in lung carcinogenesis in transforming growth factor-beta1 heterozygous mice.
Kang Y, Ozbun LL, Angdisen J, Moody TW, Prentice M, Diwan BA, Jakowlew SB., Carcinogenesis 23(7), 2002
PMID: 12117781
Heterozygous mice for the transforming growth factor-beta type II receptor gene have increased susceptibility to hepatocellular carcinogenesis.
Im YH, Kim HT, Kim IY, Factor VM, Hahm KB, Anzano M, Jang JJ, Flanders K, Haines DC, Thorgeirsson SS, Sizeland A, Kim SJ., Cancer Res. 61(18), 2001
PMID: 11559531
Expression of the TGF-beta coreceptor endoglin in epidermal keratinocytes and its dual role in multistage mouse skin carcinogenesis.
Quintanilla M, Ramirez JR, Perez-Gomez E, Romero D, Velasco B, Letarte M, Lopez-Novoa JM, Bernabeu C., Oncogene 22(38), 2003
PMID: 12955076
Myocardial fibrosis in transforming growth factor beta(1)heterozygous mice.
Brooks WW, Conrad CH., J. Mol. Cell. Cardiol. 32(2), 2000
PMID: 10722796
Decreased bone mass and bone elasticity in mice lacking the transforming growth factor-beta1 gene.
Geiser AG, Zeng QQ, Sato M, Helvering LM, Hirano T, Turner CH., Bone 23(2), 1998
PMID: 9701466
Increased levels of surgical adhesions in TGFbeta1 heterozygous mice.
Krause TJ, Katz D, Wheeler CJ, Ebner S, McKinnon RD., J Invest Surg 12(1), 1999
PMID: 10084677
Cutaneous wound healing.
Singer AJ, Clark RA., N. Engl. J. Med. 341(10), 1999
PMID: 10471461
TGF-beta and fibrosis.
Branton MH, Kopp JB., Microbes Infect. 1(15), 1999
PMID: 10611762
Immunodetection and quantitation of the two forms of transforming growth factor-beta (TGF-beta 1 and TGF-beta 2) secreted by cells in culture.
Danielpour D, Dart LL, Flanders KC, Roberts AB, Sporn MB., J. Cell. Physiol. 138(1), 1989
PMID: 2910889
Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography.
Hamelmann E, Schwarze J, Takeda K, Oshiba A, Larsen GL, Irvin CG, Gelfand EW., Am. J. Respir. Crit. Care Med. 156(3 Pt 1), 1997
PMID: 9309991
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