T-Reg Comparator: an analysis tool for the comparison of position weight matrices
Röpcke S, Grossmann S, Rahmann S, Vingron M (2005)
Nucleic Acids Research 33(Web Server): W438-W441.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
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Autor*in
Röpcke, Stefan;
Grossmann, Steffen;
Rahmann, Sven;
Vingron, Martin
Einrichtung
Abstract / Bemerkung
T-Reg Comparator is a novel software tool designed to support research into transcriptional regulation. Sequence motifs representing transcription factor binding sites are usually encoded as position weight matrices. The user inputs a set of such weight matrices or binding site sequences and our program matches them against the T-Reg database, which is presently built on data from the Transfac [E. Wingender (2004) In Silico Biol., 4, 55-61] and Jaspar [A. Sandelin, W. Alkema, P. Engstrom, W. W. Wasserman and B. Lenhard (2004) Nucleic Acids Res., 32, D91-D94]. Our tool delivers a detailed report on similarities between user-supplied motifs and motifs in the database. Apart from simple one-to-one relationships, T-Reg Comparator is also able to detect similarities between submatrices. In addition, we provide a user interface to a program for sequence scanning with weight matrices. Typical areas of application for T-Reg Comparator are motif and regulatory module finding and annotation of regulatory genomic regions. T-Reg Comparator is available at http://treg.molgen.mpg.de.
Erscheinungsjahr
2005
Zeitschriftentitel
Nucleic Acids Research
Band
33
Ausgabe
Web Server
Seite(n)
W438-W441
ISSN
0305-1048
eISSN
1362-4962
Page URI
https://pub.uni-bielefeld.de/record/1773695
Zitieren
Röpcke S, Grossmann S, Rahmann S, Vingron M. T-Reg Comparator: an analysis tool for the comparison of position weight matrices. Nucleic Acids Research. 2005;33(Web Server):W438-W441.
Röpcke, S., Grossmann, S., Rahmann, S., & Vingron, M. (2005). T-Reg Comparator: an analysis tool for the comparison of position weight matrices. Nucleic Acids Research, 33(Web Server), W438-W441. https://doi.org/10.1093/nar/gki590
Röpcke, Stefan, Grossmann, Steffen, Rahmann, Sven, and Vingron, Martin. 2005. “T-Reg Comparator: an analysis tool for the comparison of position weight matrices”. Nucleic Acids Research 33 (Web Server): W438-W441.
Röpcke, S., Grossmann, S., Rahmann, S., and Vingron, M. (2005). T-Reg Comparator: an analysis tool for the comparison of position weight matrices. Nucleic Acids Research 33, W438-W441.
Röpcke, S., et al., 2005. T-Reg Comparator: an analysis tool for the comparison of position weight matrices. Nucleic Acids Research, 33(Web Server), p W438-W441.
S. Röpcke, et al., “T-Reg Comparator: an analysis tool for the comparison of position weight matrices”, Nucleic Acids Research, vol. 33, 2005, pp. W438-W441.
Röpcke, S., Grossmann, S., Rahmann, S., Vingron, M.: T-Reg Comparator: an analysis tool for the comparison of position weight matrices. Nucleic Acids Research. 33, W438-W441 (2005).
Röpcke, Stefan, Grossmann, Steffen, Rahmann, Sven, and Vingron, Martin. “T-Reg Comparator: an analysis tool for the comparison of position weight matrices”. Nucleic Acids Research 33.Web Server (2005): W438-W441.
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