Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications

Ros R, Eckel R, Bartels FW, Sischka A, Baumgarth B, Wilking SD, Pühler A, Sewald N, Becker A, Anselmetti D (2004)
Journal of Biotechnology 112(1-2): 5-12.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Abstract / Bemerkung
Recent developments in single molecule force spectroscopy (SMFS) allow direct observation and measurements of forces that hold protein-DNA complexes together. Furthermore, the mechanics of double-stranded (ds) DNA molecules in the presence of small binding ligands can be detected. The results elucidate molecular binding mechanisms and open the way for ultra sensitive and powerful biosensor applications.
Stichworte
Optical tweezers; Single molecule force spectroscopy; Atomic force microscopy; Ligand–DNA interaction
Erscheinungsjahr
2004
Zeitschriftentitel
Journal of Biotechnology
Band
112
Ausgabe
1-2
Seite(n)
5-12
ISSN
0168-1656
Page URI
https://pub.uni-bielefeld.de/record/1773148

Zitieren

Ros R, Eckel R, Bartels FW, et al. Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications. Journal of Biotechnology. 2004;112(1-2):5-12.
Ros, R., Eckel, R., Bartels, F. W., Sischka, A., Baumgarth, B., Wilking, S. D., Pühler, A., et al. (2004). Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications. Journal of Biotechnology, 112(1-2), 5-12. doi:10.1016/j.jbiotec.2004.04.029
Ros, R., Eckel, R., Bartels, F. W., Sischka, A., Baumgarth, B., Wilking, S. D., Pühler, A., Sewald, N., Becker, A., and Anselmetti, D. (2004). Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications. Journal of Biotechnology 112, 5-12.
Ros, R., et al., 2004. Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications. Journal of Biotechnology, 112(1-2), p 5-12.
R. Ros, et al., “Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications”, Journal of Biotechnology, vol. 112, 2004, pp. 5-12.
Ros, R., Eckel, R., Bartels, F.W., Sischka, A., Baumgarth, B., Wilking, S.D., Pühler, A., Sewald, N., Becker, A., Anselmetti, D.: Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications. Journal of Biotechnology. 112, 5-12 (2004).
Ros, Robert, Eckel, Rainer, Bartels, Frank Wilco, Sischka, Andy, Baumgarth, Birgit, Wilking, Sven David, Pühler, Alfred, Sewald, Norbert, Becker, Anke, and Anselmetti, Dario. “Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications”. Journal of Biotechnology 112.1-2 (2004): 5-12.
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2019-09-06T08:48:07Z
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