Absence of intrinsic electric conductivity in single dsDNA molecules

Kleine H, Wilke R, Pelargus C, Rott K, Pühler A, Reiss G, Ros R, Anselmetti D (2004)
Journal of Biotechnology 112(1-2): 91-95.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
Download
OA
Autor*in
Kleine, Hermann; Wilke, Ralf; Pelargus, ChristophUniBi; Rott, KarstenUniBi; Pühler, AlfredUniBi ; Reiss, Günter; Ros, Robert; Anselmetti, DarioUniBi
Abstract / Bemerkung
The intrinsic dc conductivity of long, individual lambda phage dsDNA molecules has been investigated by ultrasensitive low current-voltage-spectroscopy (IV) under ambient conditions and controlled low humidity inert gas atmosphere on microfabricated metal-insulator-metal gap structures. We found a strong dependence of the measured conductivity on the apparent humidity, which we attribute to capillary condensation of water to the immobilized DNA molecules, giving rise to additional ionic currents. Additional IV-spectroscopy experiments under controlled argon atmosphere always revealed a significant drop in electrical conductivity to 4 × 10 -15 AV -1 µm -1, indicating almost no considerable contribution of electrical long range charge transport.
Stichworte
DNA conductivity; Current-voltage spectroscopy; Microstructures
Erscheinungsjahr
2004
Zeitschriftentitel
Journal of Biotechnology
Band
112
Ausgabe
1-2
Seite(n)
91-95
ISSN
0168-1656
Page URI
https://pub.uni-bielefeld.de/record/1773125

Zitieren

Kleine H, Wilke R, Pelargus C, et al. Absence of intrinsic electric conductivity in single dsDNA molecules. Journal of Biotechnology. 2004;112(1-2):91-95.
Kleine, H., Wilke, R., Pelargus, C., Rott, K., Pühler, A., Reiss, G., Ros, R., et al. (2004). Absence of intrinsic electric conductivity in single dsDNA molecules. Journal of Biotechnology, 112(1-2), 91-95. https://doi.org/10.1016/j.jbiotec.2004.04.031
Kleine, Hermann, Wilke, Ralf, Pelargus, Christoph, Rott, Karsten, Pühler, Alfred, Reiss, Günter, Ros, Robert, and Anselmetti, Dario. 2004. “Absence of intrinsic electric conductivity in single dsDNA molecules”. Journal of Biotechnology 112 (1-2): 91-95.
Kleine, H., Wilke, R., Pelargus, C., Rott, K., Pühler, A., Reiss, G., Ros, R., and Anselmetti, D. (2004). Absence of intrinsic electric conductivity in single dsDNA molecules. Journal of Biotechnology 112, 91-95.
Kleine, H., et al., 2004. Absence of intrinsic electric conductivity in single dsDNA molecules. Journal of Biotechnology, 112(1-2), p 91-95.
H. Kleine, et al., “Absence of intrinsic electric conductivity in single dsDNA molecules”, Journal of Biotechnology, vol. 112, 2004, pp. 91-95.
Kleine, H., Wilke, R., Pelargus, C., Rott, K., Pühler, A., Reiss, G., Ros, R., Anselmetti, D.: Absence of intrinsic electric conductivity in single dsDNA molecules. Journal of Biotechnology. 112, 91-95 (2004).
Kleine, Hermann, Wilke, Ralf, Pelargus, Christoph, Rott, Karsten, Pühler, Alfred, Reiss, Günter, Ros, Robert, and Anselmetti, Dario. “Absence of intrinsic electric conductivity in single dsDNA molecules”. Journal of Biotechnology 112.1-2 (2004): 91-95.
Alle Dateien verfügbar unter der/den folgenden Lizenz(en):
Copyright Statement:
Dieses Objekt ist durch das Urheberrecht und/oder verwandte Schutzrechte geschützt. [...]
Volltext(e)
Access Level
OA Open Access
Zuletzt Hochgeladen
2019-09-06T08:48:07Z
MD5 Prüfsumme
88d01a1aaf3a46268989e5ff9eb8b42b


3 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Stepwise oscillatory circuits of a DNA molecule.
Xu K., J Biol Phys 35(3), 2009
PMID: 19669574
Stepwise oscillatory circuits of a DNA molecule
Xu Kunming., J Biol Phys 35(3), 2009
PMID: IND44243393
Impedance measurements on a DNA junction.
Hong S, Jauregui LA, Rangel NL, Cao H, Day BS, Norton ML, Sinitskii AS, Seminario JM., J Chem Phys 128(20), 2008
PMID: 18513002

24 References

Daten bereitgestellt von Europe PubMed Central.

Alignment and sensitive detection of DNA by a moving interface.
Bensimon A, Simon A, Chiffaudel A, Croquette V, Heslot F, Bensimon D., Science 265(5181), 1994
PMID: 7522347
Stretching DNA with a receding meniscus: Experiments and models.
Bensimon D, Simon AJ, Croquette V V, Bensimon A., Phys. Rev. Lett. 74(23), 1995
PMID: 10058590
DNA-templated assembly and electrode attachment of a conducting silver wire.
Braun E, Eichen Y, Sivan U, Ben-Yoseph G., Nature 391(6669), 1998
PMID: 9486645
Selfasembled DNA networks and their electrical conductivity
Cai, Appl. Phys. Lett. 77(), 2000
Mechanism of charge transport in DNA: internally-linked anthraquinone conjugates support phonon-assisted polaron hopping
Danith, J. Am. Chem. Soc. 121(), 1999
Absence of dc-conductivity in lambda-DNA.
de Pablo PJ, Moreno-Herrero F, Colchero J, Gomez Herrero J, Herrero P, Baro AM, Ordejon P, Soler JM, Artacho E., Phys. Rev. Lett. 85(23), 2000
PMID: 11102169
Electrical conduction through DNA molecules.
Fink HW, Schonenberger C., Nature 398(6726), 1999
PMID: 10201370
Long distance charge transport through DNA: quantification and extension of the hopping model
Giese, Chem. Phys. Chem. 1(), 2000
Long-distance charge transport through DNA: An extended hopping model
Giese, Pure Appl. Chem. 73(3), 2001
Contactless experiments on individual DNA molecules show no evidence for molecular wire behavior.
Gomez-Navarro C, Moreno-Herrero F, de Pablo PJ, Colchero J, Gomez-Herrero J, Baro AM., Proc. Natl. Acad. Sci. U.S.A. 99(13), 2002
PMID: 12070346
Electrical transport 60bp of poly(G)-poly(C) DNA molecules
Hwang, Appl. Phys. Lett. 81(), 2002
Electrical transport through poly(G)-poly(C) DNA molecules
Hwang, Microelectron. Eng. 63(), 2002
Proximity-induced superconductivity in DNA.
Kasumov AY, Kociak M, Gueron S, Reulet B, Volkov VT, Klinov DV, Bouchiat H., Science 291(5502), 2001
PMID: 11209072
Electron transfer between bases in double helical DNA.
Kelley SO, Barton JK., Science 283(5400), 1999
PMID: 9888851
DNA-templated carbon nanotube field-effect transistor.
Keren K, Berman RS, Buchstab E, Sivan U, Braun E., Science 302(5649), 2003
PMID: 14631035
Control of electrical conduction in DNA using oxygen hole doping
Lee, Appl. Phys. Lett. 80(), 2002
Sequence dependent long range hole transport in DNA
Meggers, J. Am. Chem. Soc. 120(), 1998
Evidence for DNA charge transport in the nucleus.
Nunez ME, Holmquist GP, Barton JK., Biochemistry 40(42), 2001
PMID: 11601969
Influence of humidity on the electrical conductivity of synthesized DNA film on nanogap electrode
Otsuka, Jpn. J. Appl. Phys. 41(), 2002
Paradigms, supermolecules, electron transfer and chemistry at a distance. What’s the problem? The science or the paradigm?
Turro, JBIC 3(), 1998

AUTHOR UNKNOWN, 0
Femtosecond dynamics of DNA-mediated electron transfer.
Wan C, Fiebig T, Kelley SO, Treadway CR, Barton JK, Zewail AH., Proc. Natl. Acad. Sci. U.S.A. 96(11), 1999
PMID: 10339533

AUTHOR UNKNOWN, 0
Electrical conduction through poly(dA)-poly(dT) and poly(dG)-poly(dC) DNA molecules.
Yoo KH, Ha DH, Lee JO, Park JW, Kim J, Kim JJ, Lee HY, Kawai T, Choi HY., Phys. Rev. Lett. 87(19), 2001
PMID: 11690458
Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®
Quellen

PMID: 15288944
PubMed | Europe PMC

Suchen in

Google Scholar