Detection and manipulation of biomolecules by magnetic carriers

Brzeska M, Panhorst M, Kamp P-B, Schotter J, Reiss G, Pühler A, Becker A, Brückl H (2004)
JOURNAL OF BIOTECHNOLOGY 112(1-2): 25-33.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
Download
Es wurde kein Volltext hochgeladen. Nur Publikationsnachweis!
Autor/in
; ; ; ; ; ; ;
Abstract / Bemerkung
The detection and manipulation of single molecules on a common platform would be of great interest for basic research of biological or chemical systems. A promising approach is the application of magnetic carriers. The principles are demonstrated in this contribution. It is shown that paramagnetic beads can be detected by highly sensitive magnetoresistive sensors yielding a purely electronic signal. Different configurations are discussed. The capability of the sensors to detect even single markers is demonstrated by a model experiment. In addition, the paramagnetic beads can be used as carriers for biomolecules. They can be manipulated on-chip via currents running through specially designed line patterns. Thus, magnetic markers in combination with magnetoresistive sensors are a promising choice for future integrated lab-on-a-chip systems. (C) 2004 Elsevier B.V. All rights reserved.
Stichworte
molecular recognition; biochip; marker; sensor; bonding force; magnetoresistive
Erscheinungsjahr
2004
Zeitschriftentitel
JOURNAL OF BIOTECHNOLOGY
Band
112
Ausgabe
1-2
Seite(n)
25-33
ISSN
0168-1656
Page URI
https://pub.uni-bielefeld.de/record/1606644

Zitieren

Brzeska M, Panhorst M, Kamp P-B, et al. Detection and manipulation of biomolecules by magnetic carriers. JOURNAL OF BIOTECHNOLOGY. 2004;112(1-2):25-33.
Brzeska, M., Panhorst, M., Kamp, P. - B., Schotter, J., Reiss, G., Pühler, A., Becker, A., et al. (2004). Detection and manipulation of biomolecules by magnetic carriers. JOURNAL OF BIOTECHNOLOGY, 112(1-2), 25-33. doi:10.1016/j.jbiotec.2004.04.018
Brzeska, M., Panhorst, M., Kamp, P. - B., Schotter, J., Reiss, G., Pühler, A., Becker, A., and Brückl, H. (2004). Detection and manipulation of biomolecules by magnetic carriers. JOURNAL OF BIOTECHNOLOGY 112, 25-33.
Brzeska, M., et al., 2004. Detection and manipulation of biomolecules by magnetic carriers. JOURNAL OF BIOTECHNOLOGY, 112(1-2), p 25-33.
M. Brzeska, et al., “Detection and manipulation of biomolecules by magnetic carriers”, JOURNAL OF BIOTECHNOLOGY, vol. 112, 2004, pp. 25-33.
Brzeska, M., Panhorst, M., Kamp, P.-B., Schotter, J., Reiss, G., Pühler, A., Becker, A., Brückl, H.: Detection and manipulation of biomolecules by magnetic carriers. JOURNAL OF BIOTECHNOLOGY. 112, 25-33 (2004).
Brzeska, M, Panhorst, Maren, Kamp, Paul-Bertram, Schotter, Jörg, Reiss, Günter, Pühler, Alfred, Becker, Anke, and Brückl, Hubert. “Detection and manipulation of biomolecules by magnetic carriers”. JOURNAL OF BIOTECHNOLOGY 112.1-2 (2004): 25-33.

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 15288938
PubMed | Europe PMC

Suchen in

Google Scholar