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53 Publikationen

2019 | Bielefelder E-Dissertation | PUB-ID: 2936599
Huang, L.: Cloud-based Bioinformatics Framework for Next-Generation Sequencing Data. Universität Bielefeld, Bielefeld (2019).
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2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2934798
Pankoke, H., Maus, I., Loh, G., Huser, A., Seifert, J., Tilker, A., Hark, S., Sczyrba, A., Pelzer, S., Kleinbolting, J.: F5Evaluation of commercially available DNA extraction kits for the analysis of the broiler chicken cecal microbiota. FEMS microbiology letters. (2019).
PUB | DOI | PubMed | Europe PMC
 
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2935923
Nelkner, J., Henke, C., Lin, T.W., Pätzold, W., Hassa, J., Jaenicke, S., Grosch, R., Pühler, A., Sczyrba, A., Schlüter, A.: Effect of Long-Term Farming Practices on Agricultural Soil Microbiome Members Represented by Metagenomically Assembled Genomes (MAGs) and Their Predicted Plant-Beneficial Genes. Genes. 10, : 424 (2019).
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2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2933767
Fritz, A., Hofmann, P., Majda, S., Dahms, E., Dröge, J., Fiedler, J., Lesker, T.R., Belmann, P., DeMaere, M.Z., Darling, A.E., Sczyrba, A., Bremges, A., McHardy, A.C.: CAMISIM: simulating metagenomes and microbial communities. Microbiome. 7, : 17 (2019).
PUB | DOI | WoS | PubMed | Europe PMC
 
2018 | Bielefelder E-Dissertation | PUB-ID: 2918990
Rumming, M.: Metadata-driven computational (meta)genomics. A practical machine learning approach. Universität Bielefeld, Bielefeld (2018).
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920777
Celis, J.S., Wibberg, D., Ramírez-Portilla, C., Rupp, O., Sczyrba, A., Winkler, A., Kalinowski, J., Wilke, T.: Binning Enables Efficient Host Genome Reconstruction in Cnidarian Holobionts. GigaScience. 7, : giy075 (2018).
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2916929
Stolze, Y., Bremges, A., Maus, I., Pühler, A., Sczyrba, A., Schlüter, A.: Targeted in situ metatranscriptomics for selected taxa from mesophilic and thermophilic biogas plants. Microbial Biotechnology. 11, 667-679 (2018).
PUB | DOI | WoS | PubMed | Europe PMC
 
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2930593
Linden, M., Prochazka, M., Lappalainen, I., Bucik, D., Vyskocil, P., Kuba, M., Silén, S., Belmann, P., Sczyrba, A., Newhouse, S., Matyska, L., Nyrönen, T.: Common ELIXIR Service for Researcher Authentication and Authorisation. F1000Research. 7, : 1199 (2018).
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920723
Meyer, F., Hofmann, P., Belmann, P., Garrido-Oter, R., Fritz, A., Sczyrba, A., McHardy, A.C.: AMBER: Assessment of Metagenome BinnERs. GigaScience. : giy069 (2018).
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2915890
Huang, L., Krüger, J., Sczyrba, A.: Analyzing large scale genomic data on the cloud with Sparkhit. Bioinformatics. 34, 1457-1465 (2018).
PUB | DOI | WoS | PubMed | Europe PMC
 
2018 | Bielefelder Masterarbeit | PUB-ID: 2919932
Wiens, M.: Concept, design and initial implementation of the de.NBI Cloud Portal. Universität Bielefeld, Bielefeld (2018).
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920750
Maus, I., Rumming, M., Bergmann, I., Heeg, K., Pohl, M., Nettmann, E., Jaenicke, S., Blom, J., Pühler, A., Schlüter, A., Sczyrba, A., Klocke, M.: Characterization of Bathyarchaeota genomes assembled from metagenomes of biofilms residing in mesophilic and thermophilic biogas reactors. Biotechnology for Biofuels. 11, : 167 (2018).
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2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2918275
Fleming, E.J., Woyke, T., Donatello, A.R., Kuypers, M.M.M., Sczyrba, A., Littmann, S., Emerson, D.: Insights into the fundamental physiology of the uncultured Fe-oxidizing bacterium Leptothrix ochracea. Applied and Environmental Microbiology. 84, : e02239-17 (2018).
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2909153
Yu, J., Blom, J., Sczyrba, A., Goesmann, A.: Rapid protein alignment in the cloud: HAMOND combines fast DIAMOND alignments with Hadoop parallelism. Journal of Biotechnology. 257, 58-60 (2017).
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2913556
Jünemann, S., Kleinbölting, N., Jaenicke, S., Henke, C., Hassa, J., Nelkner, J., Stolze, Y., Albaum, S., Schlüter, A., Goesmann, A., Sczyrba, A., Stoye, J.: Bioinformatics for NGS-based metagenomics and the application to biogas research. Journal of Biotechnology. 261, 10-23 (2017).
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2017 | Datenpublikation | PUB-ID: 2914921
Huang, L., Krüger, J., Sczyrba, A.: Sparkhit evaluation data set. Bielefeld University (2017). doi:10.4119/unibi/2914921.
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2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2914367
Sczyrba, A., Hofmann, P., Belmann, P., Koslicki, D., Janssen, S., Dröge, J., Gregor, I., Majda, S., Fiedler, J., Dahms, E., Bremges, A., Fritz, A., Garrido-Oter, R., Jørgensen, T.S., Shapiro, N., Blood, P.D., Gurevich, A., Bai, Y., Turaev, D., DeMaere, M.Z., Chikhi, R., Nagarajan, N., Quince, C., Meyer, F., Balvočiūtė, M., Hansen, L.H., Sørensen, S.J., Chia, B.K.H., Denis, B., Froula, J.L., Wang, Z., Egan, R., Don Kang, D., Cook, J.J., Deltel, C., Beckstette, M., Lemaitre, C., Peterlongo, P., Rizk, G., Lavenier, D., Wu, Y.-W., Singer, S.W., Jain, C., Strous, M., Klingenberg, H., Meinicke, P., Barton, M.D., Lingner, T., Lin, H.-H., Liao, Y.-C., Silva, G.G.Z., Cuevas, D.A., Edwards, R.A., Saha, S., Piro, V.C., Renard, B.Y., Pop, M., Klenk, H.-P., Göker, M., Kyrpides, N.C., Woyke, T., Vorholt, J.A., Schulze-Lefert, P., Rubin, E.M., Darling, A.E., Rattei, T., McHardy, A.C.: Critical Assessment of Metagenome Interpretation—a benchmark of metagenomics software. Nature Methods. 14, 1063-1071 (2017).
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904815
Stolze, Y., Bremges, A., Rumming, M., Henke, C., Maus, I., Pühler, A., Sczyrba, A., Schlüter, A.: Identification and genome reconstruction of abundant distinct taxa in microbiomes from one thermophilic and three mesophilic production-scale biogas plants. Biotechnology for Biofuels. 9, : 156 (2016).
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2016 | Bielefelder E-Dissertation | PUB-ID: 2906743
Bremges, A.: Assembling the microbial dark matter. Universität Bielefeld, Bielefeld (2016).
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2907633
Lux, M., Krüger, J., Rinke, C., Maus, I., Schlüter, A., Woyke, T., Sczyrba, A., Hammer, B.: acdc – Automated Contamination Detection and Confidence estimation for single-cell genome data. BMC Bioinformatics. 17, : 543 (2016).
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904836
Heyer, R., Benndorf, D., Kohrs, F., De Vrieze, J., Boon, N., Hoffmann, M., Rapp, E., Schlüter, A., Sczyrba, A., Reichl, U.: Proteotyping of biogas plant microbiomes separates biogas plants according to process temperature and reactor type. Biotechnology for Biofuels. 9, : 155 (2016).
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2903489
Maus, I., Cibis, K.G., Bremges, A., Stolze, Y., Wibberg, D., Tomazetto, G., Blom, J., Sczyrba, A., König, H., Pühler, A., Schlüter, A.: Genomic characterization of Defluviitoga tunisiensis L3, a key hydrolytic bacterium in a thermophilic biogas plant and its abundance as determined by metagenome fragment recruitment. Journal of Biotechnology. 232, 50-60 (2016).
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2903302
Wibberg, D., Bremges, A., Dammann-Kalinowski, T., Maus, I., Igeño, M.I., Vogelsang, R., König, C., Luque-Almagro, V.M., Roldán, M.D., Sczyrba, A., Moreno-Vivián, C., Blasco, R., Pühler, A., Schlüter, A.: Finished genome sequence and methylome of the cyanide-degrading Pseudomonas pseudoalcaligenes strain CECT5344 as resolved by single-molecule real-time sequencing. Journal of Biotechnology. 232, 61-68 (2016).
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2902190
Stiefel, F., Fischer, S., Sczyrba, A., Otte, K., Hesse, F.: miRNA profiling of high, low and non-producing CHO cells during biphasic fed-batch cultivation reveals process relevant targets for host cell engineering. Journal of Biotechnology. 225, 31-43 (2016).
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2901418
Campos, S.B., Lisboa, B.B., Camargo, F.A.O., Bayer, C., Sczyrba, A., Dirksen, P., Albersmeier, A., Kalinowski, J., Beneduzi, A., Costa, P.B., Passaglia, L.M.P., Vargas, L.K., Wendisch, V.F.: Soil suppressiveness and its relations with the microbial community in a Brazilian subtropical agroecosystem under different management systems. Soil Biology and Biochemistry. 96, 191-197 (2016).
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2901729
Bremges, A., Singer, E., Woyke, T., Sczyrba, A.: MeCorS: Metagenome-enabled error correction of single cell sequencing reads. Bioinformatics. 32, 2199-2201 (2016).
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2900928
Nesme, J., Achouak, W., Agathos, S., Bailey, M., Baldrian, P., Brunel, D., Frostegard, A., Heulin, T., Jansson, J.K., Jurkevitch, E., Kowalchuk, G.A., Kruus, K.L., Lagares, A., Lapin-Scott, H.M., Le Paslier, D., ic-Mulec, I., Murrell, C., Myrold, D.D., Nalin, R., Nannipieri, P., Neufeld, J.D., O'Gara, F., Parnell, J.J., Pühler, A., Pylro, V., Ramos, J.L., Roesch, L., Schleper, C., Schloter, M., Sczyrba, A., Sessitsch, A., Sjöling, S., Sørensen, J., Sørensen, S.J., Tebbe, C.C., Topp, E., Tsiamis, G., Van Elsas, J.D., Van Keulen, G., Wagner, M., Widmer, F., Zhang, T., Zhang, X., Zhao, L., Zhu, Y.-G., Vogel, T.M., Simonet, P.: Back to the future of soil metagenomics. Frontiers in Microbiology. 7, : 73 (2016).
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2901675
Krahn, T., Wibberg, D., Maus, I., Winkler, A., Bontron, S., Sczyrba, A., Nordmann, P., Pühler, A., Poirel, L., Schlüter, A.: Intraspecies transfer of the chromosomally encoded Acinetobacter baumannii blaNDM-1 carbapenemase gene. Antimicrobial Agents and Chemotherapy. 60, 3032-3040 (2016).
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2905260
Maus, I., Koeck, D.E., Cibis, K.G., Hahnke, S., Kim, Y.S., Langer, T., Kreubel, J., Erhard, M., Bremges, A., Off, S., Stolze, Y., Jaenicke, S., Goesmann, A., Sczyrba, A., Scherer, P., König, H., Schwarz, W.H., Zverlov, V.V., Liebl, W., Pühler, A., Schlüter, A., Klocke, M.: Unraveling the microbiome of a thermophilic biogas plant by metagenome and metatranscriptome analysis complemented by characterization of bacterial and archaeal isolates. Biotechnology for Biofuels. 9, : 171 (2016).
PUB | DOI | WoS | PubMed | Europe PMC
 
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904234
Ortseifen, V., Stolze, Y., Maus, I., Sczyrba, A., Bremges, A., Albaum, S., Jaenicke, S., Fracowiak, J., Pühler, A., Schlüter, A.: An integrated metagenome and -proteome analysis of the microbial community residing in a biogas production plant. Journal of Biotechnology. 231, 268-279 (2016).
PUB | DOI | WoS | PubMed | Europe PMC
 
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2764906
Bremges, A., Maus, I., Belmann, P., Eikmeyer, F.G., Winkler, A., Albersmeier, A., Pühler, A., Schlüter, A., Sczyrba, A.: Deeply sequenced metagenome and metatranscriptome of a biogas-producing microbial community from an agricultural production-scale biogas plant. GigaScience. 4, : 33 (2015).
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2762833
Kohrs, F., Wolter, S., Benndorf, D., Heyer, R., Hoffmann, M., Rapp, E., Bremges, A., Sczyrba, A., Schlüter, A., Reichl, U.: Fractionation of biogas plant sludge material improves metaproteomic characterization to investigate metabolic activity of microbial communities. Proteomics. 15, 3585-3589 (2015).
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2726183
Field, E.K., Sczyrba, A., Lyman, A.E., Harris, C.C., Woyke, T., Stepanauskas, R., Emerson, D.: Genomic insights into the uncultivated marine Zetaproteobacteria at Loihi Seamount. The ISME journal. 9, 857-870 (2015).
PUB | DOI | WoS | PubMed | Europe PMC
 
2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2782501
Belmann, P., Dröge, J., Bremges, A., McHardy, A.C., Sczyrba, A., Barton, M.D.: Bioboxes: standardised containers for interchangeable bioinformatics software. GigaScience. 4, : 47 (2015).
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2015 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2901612
Lux, M., Sczyrba, A., Hammer, B.: Automatic discovery of metagenomic structure. 2015 International Joint Conference on Neural Networks (IJCNN). Institute of Electrical & Electronics Engineers (IEEE) (2015).
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2726156
Paul, B.G., Bagby, S.C., Czornyj, E., Arambula, D., Handa, S., Sczyrba, A., Ghosh, P., Miller, J.F., Valentine, D.L.: Targeted diversity generation by intraterrestrial archaea and archaeal viruses. Nature Communications. 6, 6585 (2015).
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2015 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2901462
Rumming, M., Krusche, P., Tedder, P.M.: Developing gold standard variant calls for whole-genome somatic variant calling using supervised learning. Presented at the Cancer Genomics - EMBL Conference, EMBL Heidelberg (2015).
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2015 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2901466
Osterholz, B., Wiebke, P., Fust, A., Rumming, M., Schlüter, A., Sczyrba, A.: A Bioinformatics Pipeline for the Detection of β-lactamase Genes in Metagenome Sequence Data and its Application to Production-Scale Biogas Plants. Presented at the 3rd International Symposium on the environmental Dimension of Antibiotic Resistance, Wernigerode (2015).
PUB
 
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2685992
Piao, H., Lachman, M., Malfatti, S., Sczyrba, A., Knierim, B., Auer, M., Tringe, S.G., Mackie, R.I., Yeoman, C.J., Hess, M.: Temporal dynamics of fibrolytic and methanogenic rumen microorganisms during in situ incubation of switchgrass determined by 16S rRNA gene profiling. Frontiers in Microbiology. 5, (2014).
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2654433
Kamke, J., Rinke, C., Schwientek, P., Mavromatis, K., Ivanova, N., Sczyrba, A., Woyke, T., Hentschel, U.: The Candidate Phylum Poribacteria by Single-Cell Genomics: New Insights into Phylogeny, Cell-Compartmentation, Eukaryote-Like Repeat Proteins, and Other Genomic Features. PLoS ONE. 9, : e87353 (2014).
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2689051
Ghylin, T.W., Garcia, S.L., Moya, F., Oyserman, B.O., Schwientek, P., Forest, K.T., Mutschler, J., Dwulit-Smith, J., Chan, L.-K., Martinez-Garcia, M., Sczyrba, A., Stepanauskas, R., Grossart, H.-P., Woyke, T., Warnecke, F., Malmstrom, R., Bertilsson, S., McMahon, K.D.: Comparative single-cell genomics reveals potential ecological niches for the freshwater acI Actinobacteria lineage. The ISME Journal. 8, 2503-2516 (2014).
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2672695
Swan, B.K., Chaffin, M.D., Martinez-Garcia, M., Morrison, H.G., Field, E.K., Poulton, N.J., Masland, E.D.P., Harris, C.C., Sczyrba, A., Chain, P.S.G., Koren, S., Woyke, T., Stepanauskas, R.: Genomic and metabolic diversity of marine group I thaumarchaeota in the mesopelagic of two subtropical gyres. PloS one. 9, 95380 (2014).
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2665333
Henrich, B., Rumming, M., Sczyrba, A., Velleuer, E., Dietrich, R., Gerlach, W., Gombert, M., Rahn, S., Stoye, J., Borkhardt, A., Fischer, U.: Mycoplasma salivarium as a Dominant Coloniser of Fanconi Anaemia Associated Oral Carcinoma. PLoS ONE. 9, e92297 (2014).
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2662055
Wibberg, D., Luque-Almagro, V.M., Igeño, M.I., Bremges, A., Roldán, M.D., Merchán, F., Sáez, L.P., Guijo, M.I., Manso, M.I., Macías, D., Cabello, P., Becerra, G., Ibáñez, M.I., Carmona, M.I., Escribano, M.P., Castillo, F., Sczyrba, A., Moreno-Vivián, C., Blasco, R., Pühler, A., Schlüter, A.: Complete genome sequence of the cyanide-degrading bacterium Pseudomonas pseudoalcaligenes CECT5344. Journal of biotechnology. 175, 67-68 (2014).
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2013 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2623500
Gisbrecht, A., Hammer, B., Mokbel, B., Sczyrba, A.: Nonlinear dimensionality reduction for cluster identification in metagenomic samples. In: Banissi, E. (ed.) 17th International Conference on Information Visualisation IV 2013. p. 174-179. (2013).
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2613567
Rinke, C., Schwientek, P., Sczyrba, A., Ivanova, N.N., Anderson, I.J., Cheng, J.-F., Darling, A., Malfatti, S., Swan, B.K., Gies, E.A., Dodsworth, J.A., Hedlund, B.P., Tsiamis, G., Sievert, S.M., Liu, W.-T., Eisen, J.A., Hallam, S.J., Kyrpides, N.C., Stepanauskas, R., Rubin, E.M., Hugenholtz, P., Woyke, T.: Insights into the phylogeny and coding potential of microbial dark matter. Nature. 499, 431-437 (2013).
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2563424
Campbell, J.H., O'Donoghue, P., Campbell, A.G., Schwientek, P., Sczyrba, A., Woyke, T., Söll, D., Podar, M.: UGA is an additional glycine codon in uncultured SR1 bacteria from the human microbiota. Proceedings of the National Academy of Sciences of the United States of America. 110, 5540-5545 (2013).
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2638234
Zaremba-Niedzwiedzka, K., Viklund, J., Zhao, W., Ast, J., Sczyrba, A., Woyke, T., McMahon, K., Bertilsson, S., Stepanauskas, R., Andersson, S.G.: Single-cell genomics reveal low recombination frequencies in freshwater bacteria of the SAR11 clade. Genome biology. 14, R130 (2013).
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2641352
Kamke, J., Sczyrba, A., Ivanova, N., Schwientek, P., Rinke, C., Mavromatis, K., Woyke, T., Hentschel, U.: Single-cell genomics reveals complex carbohydrate degradation patterns in poribacterial symbionts of marine sponges. The ISME journal. 7, 2287-2300 (2013).
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2563543
Campbell, A.G., Campbell, J.H., Schwientek, P., Woyke, T., Sczyrba, A., Allman, S., Beall, C.J., Griffen, A., Leys, E., Podar, M.: Multiple Single-Cell Genomes Provide Insight into Functions of Uncultured Deltaproteobacteria in the Human Oral Cavity. PLoS ONE. 8, : e59361 (2013).
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2613623
Swan, B.K., Tupper, B., Sczyrba, A., Lauro, F.M., Martinez-Garcia, M., González, J.M., Luo, H., Wright, J.J., Landry, Z.C., Hanson, N.W., Thompson, B.P., Poulton, N.J., Schwientek, P., Acinas, S.G., Giovannoni, S.J., Moran, M.A., Hallam, S.J., Cavicchioli, R., Woyke, T., Stepanauskas, R.: Prevalent genome streamlining and latitudinal divergence of planktonic bacteria in the surface ocean. Proceedings of the National Academy of Sciences of the United States of America. 110, 11463-11468 (2013).
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2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1784020
Lamprecht, A.-L., Margaria, T., Steffen, B., Sczyrba, A., Hartmeier, S., Giegerich, R.: GeneFisher-P: variations of GeneFisher as processes in Bio-jETI. BMC Bioinformatics. 9, S13 (2008).
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2008 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 1588303
Sczyrba, A., Konermann, S., Giegerich, R.: Two interactive bioinformatics courses at the bielefeld university bioinformatics server. BRIEFINGS IN BIOINFORMATICS. 9, 243-249 (2008).
PUB | DOI | WoS | PubMed | Europe PMC
 

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