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199 Publikationen

2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912509
A. Rudat, et al., “Microfluidic cultivation chamber for the investigation of synthetic microbial co-cultures on single-cell level: From the development to first application”, Presented at the BioProcessing Days 2017, Recklinghausen, Germany, 2017.
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912522
C.C. Sachs, et al., “Image-Based Single Cell Profiling: High-Throughput Processing of Mother Machine Experiments”, PLoS one, vol. 11, 2016, : e0163453 -.
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912514
D. Binder, et al., “Comparative Single-Cell Analysis of Different E. coli Expression Systems during Microfluidic Cultivation”, PLoS one, vol. 11, 2016, : e0160711.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912527
A. Grünberger, “Microfluidic single-cell cultivation: Is small the new beautiful?”, Presented at the 6th International Bielefeld-CeBiTec Research Conference: Advances in Industrial Biotechnology: New Techniques, Substrates and Products for Bioprocesses, Bielefeld, Germany, 2016.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912534
A. Grünberger, “Single-cell microfluidics for bioprocess development”, Presented at the GreenWin Conferences “Green Chemistry and White Biotechnology", Gembloux, Belgium, 2016.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912539
C. Westerwalbesloh, et al., “Nutrient distribution in perfusion based picoliter bioreactors”, Presented at the 4th BioProScale Symposium "Bioprocess intensification through process analytical technology (PAT) and quality by design (QbD)", Berlin, Germany, 2016.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912820
J. Hage-Hülsmann, et al., “Combinatorial antibiotic effects of natural biocide cocktails”, Presented at the IV International Conference on Antimicrobial Research, Malaga, Spain, 2016.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912761
A. Grünberger, “Microfluidic single-cell bioreactors. Introduction, application and future perspectives”, Presented at the LCSB Biannual Minisymposia in Modelling/Automation/Microfluidics at the University of Luxembourg, Esch-sur-Alzette, Luxembourg, 2016.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912803
D. Binder, et al., “Employing photocaged carbohydrates in light-controlled cell factories for synthetic bio(techno)logy and single cell applications”, Presented at the Annual Conference of the Association for General and Applied Microbiology (VAAM),, Jena, Germany, 2016.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912512
C. Bier, et al., “Sugar Based Caged Compounds for Biotechnological Synthetic Biological Applications”, Presented at the 26th IUPAC Symposium on Photochemistry, Osaka, Japan, 2016.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912524
C. Brehl, et al., “Microfluidic cultivation of the microalgae Chlorella sorokiniana on single-cell level at defined environments”, Presented at the 9. DECHEMA Bundesalgenstammtisch, Jülich, Germany, 2016.
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2016 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2912526
C. Westerwalbesloh, et al., “Comparison of different cultivation chamber designs for microfluidic bioreactors”, Chemie Ingenieur Technik, vol. 88, 2016, pp. 1390.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912529
A. Grünberger, et al., “Microbial metabolic state diagrams: Using microfluidic single-cell cultivation to predict bacterial gene expresssion”, Presented at the EMBL Conference Microfluidics, Heidelberg, Germany, 2016.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912531
C. Westerwalbesloh, et al., “Modeling inhomogeneities across cultivation chamber arrays in single-cell cultivation devices”, Presented at the EMBL Conference Microfluidics, Heidelberg (Germany, 2016.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912536
C.C. Sachs, et al., “An integrated platform for dynamic microfluidic experimentation with single-cell resolution”, Presented at the DECHEMA-Tagung 'Single Cell Technologies 2016', Frankfurt, Germany, 2016.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912538
I. Steffens, et al., “Bacterial phase diagrams. Analyzing and predicting cell-to-cell heterogeneity of microbial gene expression”, Presented at the 4th BioProScale Symposium "Bioprocess intensification through process analytical technology (PAT) and quality by design (QbD)", Berlin (Germany), 2016.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912540
A. Grünberger, et al., “Bacterial phase diagrams – Using engineering concepts to predict cell-to-cell heterogeneity of microbial gene expression”, Presented at the Jahrestagung 2016 der Vereinigung für Allgemeine und Angewandte Mikrobiologie, Jena, Germany, 2016.
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2016 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912552
C. Probst, et al., “Closing the gap between microfluidic single-cell analysis and bioprocess development for microbial organisms”, 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015), Red Hook, NY: Curran Associates, Inc., 2016, pp.537-539.
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912513
P.M. Kusen, et al., “Optogenetic Regulation of Tunable Gene Expression in Yeast Using Photo-Labile Caged Methionine”, ACS chemical biology, vol. 11, 2016, pp. 2915-2922.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912525
A. Burmeister, et al., “Microfluidic heterogeneity analysis of fluorescence-based gene expression of industrially relevant production strains on single-cell level”, Presented at the 18. Heiligenstädter Kolloquium „Technische Systeme für die Lebenswissenschaften, Heiligenstadt, Germany, 2016.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912532
C. Westerwalbesloh, et al., “Characterizing substrate availability within microfluidic tools employed for the analysis of genetically modified single cells”, Presented at the 1. International Conference on Molecular Interaction Engineering (MIE), Karlsruhe, Germany, 2016.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912537
A. Grünberger, W. Wiechert, and D. Kohlheyer, “Bioprocesses under magnification. Learning from single cells about large-scale processes”, Presented at the 4th BioProScale Symposium "Bioprocess intensification through process analytical technology (PAT) and quality by design (QbD)", Berlin, Germany, 2016.
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912544
D. Binder, et al., “Photocaged Arabinose - A Novel Optogenetic Switch for Rapid and Gradual Control of Microbial Gene Expression”, ChemBioChem, vol. 17, 2016, pp. 296-299.
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912739
S. Li, et al., “Enhanced protein and biochemical production using CRISPRi-based growth switches”, Metabolic Engineering, vol. 38, 2016, pp. 274-284.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912760
A. Grünberger, “Picoliter bioreactors for microbial consortia: A novel concept to investigate microbial interactions at the single-cell level”, Presented at the SynComBio Workshop “Applications of synthetic microbial communities in bioeconomy", Düsseldorf, Germany, 2016.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912772
A. Grünberger, et al., “Spatio-temporal analysis of bacterial populations at single-cell level”, Presented at the IBG Modelling Workshop, Jülich, Germany, 2016.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912511
C. Bier, et al., “Photocaged Carbohydrates: Versatile Tools for Biotechnological Applications”, Presented at the 18th International Conference on Photochemistry, Paris, France, 2016.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912523
C. Brehl, et al., “Microfluidic cultivation of the microalgae Chlorella sorokiniana on single-cell level at defined environments”, Presented at the ProcessNet 2016, Aachen, Germany, 2016.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912530
E. Kaganovitch, et al., “Single-cell analysis of E. coli in microfluidic batch reactors”, Presented at the EMBL Conference Microfluidics, Heidelberg (Germany, 2016.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912535
A. Grünberger, et al., “Bacterial phase diagrams: A novel concept to predict and control bacterial gene expression”, Presented at the DECHEMA-Himmelfahrtstagung: New Frontiers for Biotech Processes, Koblenz, Germany, 2016.
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904866
D. Binder, et al., “Light-controlled cell factories – Employing photocaged IPTG for light-mediated optimization of lac-based gene expression and (+)-valencene biosynthesis in Corynebacterium glutamicum”, Appl Environ Microbiol, vol. 82, 2016, pp. 6141-6149.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912554
C.E.M. Krämer, et al., “Non-Invasive Microbial Metabolic Activity Sensing at Single Cell Level by Perfusion of Calcein Acetoxymethyl Ester”, PLoS one, vol. 10, 2015, : e0141768.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912541
D. Binder, et al., “Light-controlled cell factories - Employing optogenetic plug-and-play expression modules based on photocaged carbohydrates for synthetic bio(techno)logy and single cell applications”, Presented at the ESP Photobiology conference, Aveiro, Portugal, 2015.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912546
A. Grünberger, W. Wiechert, and D. Kohlheyer, “Single-cell microfluidics: A key technology to understand life at environmental defined conditions”, Presented at the Kick-off Konferenz: Leben? - Eine neue Förderinitiative stellt sich vor, Hannover, Germany, 2015.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912560
E. Zunic, et al., “Dynamic environmental control in microfluidic devices for single-cell Analysis of biological production processes”, Presented at the Kolloquium Synthetic Biology - Opportunities for Interdisciplinary Research from Biology to Engineering, Aachen, Germany, 2015.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912565
A. Grünberger, et al., “Single-cell microfluidics meets applied biotechnology. From expectation to application”, Presented at the Conference "Cell Factories and Biosustainability - Technologies for Cell Factory Construction", Hillerod, Denmark, 2015.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912584
C. Probst, et al., “Rapid inoculation of single bacteria into parallel picoliter fermentation chambers”, Analytical methods, vol. 7, 2015, pp. 91-98.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912773
A. Grünberger, et al., “Single-cell microfluidics meets applied biotechnology. From expectation to application”, Presented at the Jahreskongress Biotechnologie 2020+, Berlin, Germany, 2015.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912545
A. Loeschcke, et al., “Heterologous production of antibacterial secondary metabolites from Serratia marcescens in Pseudomonas putida”, Presented at the 6th Congress of European Microbiologists (FEMS 2015), Maastricht, Netherlands, 2015.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912548
C. Bier, et al., “Caged Compounds for Biotechnological and Synthetic Biological Applications”, Presented at the European Society for Photobiology 2015 Congress, Aveiro, Portugal, 2015.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912550
A. Grünberger, et al., “Spatiotemporal microbial single-cell analysis using a high-throughput microfluidics cultivation platform”, Cytometry / A, vol. 87, 2015, pp. 1101–1115.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912555
S. Helfrich, et al., “Vizardous: interactive analysis of microbial populations with single cell resolution”, Bioinformatics, vol. 31, 2015, pp. 3875-3877.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912557
C. Westerwalbesloh, et al., “Modeling and CFD Simulation of nutrient Distribution in picoliter bioreactors for bacterial growth studies on single-cell level”, Lab on a chip, vol. 15, 2015, pp. 4177-4186.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912562
A. Grünberger, “Einzelzell-Bioreaktoren - fast unsichtbar, aber nicht unscheinbar”, Biospektrum, vol. 21, 2015, pp. 353-353.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912567
A. Grünberger, “Single-cell bioreactors: Improving the understanding of microbial metabolism”, Presented at the 30. Jahrestagung der Vereinigung für Allgemeine und Angewandte Mikrobiologie, Marburg (Germany, 2015.
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2015 | Dissertation | Veröffentlicht | PUB-ID: 2912574
A. Grünberger, Single-Cell Analysis of Microbial Production Strains in Microfluidic Bioreactors, Schriften des Forschungszentrums Jülich. Reihe Schlüsseltechnologien / Key Technologies, vol. 114, Jülich: RWTH Aachen, 2015.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912549
R. Mahr, et al., “Metabolite biosensors for single cell Analysis and the Evolution of production strains”, Presented at the 30. Jahrestagung der Vereinigung für Allgemeine und Angewandte Mikrobiologie, Marburg, Germany, 2015.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912551
C. Probst, et al., “Genetically encoded sensor analysis with spatial and temporal Resolution by time-lapse imaging”, Presented at the 1st Evaluation Symposium, Molecular Interaction Engineering, MIE-Project, Karlsruhe, Germany, 2015.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912556
D. Binder, et al., “Lichtgesteuerte Genexpression auf Einzelzellebene”, Biospektrum, vol. 21, 2015, pp. 612-615.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912563
C.C. Sachs, et al., “High-throughput, long-term growth characterization of C. glutamicum on single cell level using the Mother Machine”, Presented at the 3rd International Conference of the Cluster of Excellence Tailor-Made Fuels from Biomass, Aachen, Germany, 2015.
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