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199 Publikationen

2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2614036
Baumgart, M., Unthan, S., Rückert, C., Sivalingam, J., Grünberger, A., Kalinowski, J., Bott, M., Noack, S., and Frunzke, J. (2013). Construction of a prophage-free variant of Corynebacterium glutamicum ATCC 13032 - a platform strain for basic research and industrial biotechnology. Applied and environmental microbiology 79, 6006-6015.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912599 OA
Grünberger, A., Probst, C., Heyer, A., Wiechert, W., Frunzke, J., and Kohlheyer, D. (2013). Microfluidic Picoliter Bioreactor for Microbial Single-cell Analysis: Fabrication, System Setup, and Operation. Journal of visualized experiments. Bioengineering 82:UNSP e50560.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912602
Grünberger, A., Helfrich, S., Mustafi, N., Probst, C., Frunzke, J., Nöh, K., Wiechert, W., and Kohlheyer, D. (2013).“Automated High-Throughput Time-Lapse Microscopy of Bacteria Microcolonies in Parallelized Monolayer Growth Chambers”. Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications, Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912607
Nanda, A., Heyer, A., Krämer, C., Grünberger, A., Kohlheyer, D., and Frunzke, J. (2013).“SOS-induced spontaneous prophage induction in Corynebacterium glutamicum”. Presented at the Nikon Symposium on Advanced Imaging in Cell- and Microbiology Technology and Applications, Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912614
Krämer, C., Grünberger, A., Probst, C., Wiechert, W., and Kohlheyer, D. (2013).“Continuous Non-Invasive Real-Time Viability Measurement of Bacteria on Single Cell Level in Microfluidic Chip Cultures”. Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912619
Grünberger, A., Probst, C., Wiechert, W., and Kohlheyer, D. (2013).“Femtoliter chemostat for long-term bacteria growth and production analysis on single cell level”. Presented at the 2nd International Conference Implementation of Microreactor Technology in Biotechnology, Cavtat, Croatia.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912621
Grünberger, A., Mustafi, N., Probst, C., Frunzke, J., Wiechert, W., and Kohlheyer, D. (2013).“Towards High-Throughput Microbial Single Cell Analysis In Picoliter Bioreactors”. Presented at the 9th European Congress of Chemical Engineering, Den Haag, The Netherlands.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912626
Grünberger, A., Probst, C., Wiechert, W., and Kohlheyer, D. (2013).“Femtoliter chemostat for long-term bacteria growth and production analysis on single cell level”. Presented at the Single Cell Analysis Europe 2013, Barcelona, Spain.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912809
Frunzke, J., Mahr, R., Grünberger, A., Mustafi, N., and Kohlheyer, D. (2013).“Microbial Metabolite Production – Live in Concert”. Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912828
Krämer, C., Grünberger, A., Probst, C., Wiechert, W., and Kohlheyer, D. (2013).“Continuous Non-Invasive Real-Time Viability Measurement of Bacteria on Single Cell Level in Microfluidic Chip Cultures?”. Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912830
Probst, C., Grünberger, A., Krämer, C., Wiechert, W., and Kohlheyer, D. (2013).“Microfluidic single-cell analysis in dynamic environments”. Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912835
Mahr, R., Mustafi, N., Grünberger, A., Helfrich, S., Nöh, K., Kohlheyer, D., and Frunzke, J. (2013).“Application of a genetically- encoded metabolite sensor for single cell analysis and the development of production strains”. Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912826
Helfrich, S., Azzouzi, C. E., Grünberger, A., Wiechert, W., and Nöh, K. (2013).“Exploration and Analysis of cell population development. Customizable interactive lineage trees”. Presented at the Jülich Biotech Day, Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912833
Nanda, A. M., Heyer, A., Grünberger, A., Helfrich, S., Kohlheyer, D., Nöh, K., and Frunzke, J. (2013).“Single-cell dynamics of the SOS response in Corynebacterium glutamicum”. Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912600
Probst, C., Grünberger, A., Wiechert, W., and Kohlheyer, D. (2013). Microfluidic growth chambers with optical tweezers for full spatial single-cell control and analysis of evolving microbes. Journal of microbiological methods 95, 470-476.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912612
Nanda, A., Heyer, A., Krämer, C., Grünberger, A., Kohlheyer, D., and Frunzke, J. (2013).“SOS-induced spontaneous prophage induction in Corynebacterium glutamicum”. Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912617
Krämer, C., Grünberger, A., Probst, C., Wiechert, W., and Kohlheyer, D. (2013).“Continuous viability fluorescent staining of growing Corynebacterium glutamicum colonies without sample preparation in an automated microfluidic measurement system”. Presented at the How Deas Is Dead III Conference, Berlin, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912624
Grünberger, A., Mustafi, N., Probst, C., Frunzke, J., Wiechert, W., and Kohlheyer, D. (2013).“High-throughput Microbial Single Cell analysis in Picoliter Bioreactors”. Presented at the VAAM-Tagung 2013, Bremen, Germany.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912631
Grünberger, A., van Ooyen, J., Paczia, N., Rohe, P., Schendzielorz, G., Eggeling, L., Wiechert, W., Kohlheyer, D., and Noack, S. (2013). Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments. Biotechnology and bioengineering 110, 220-228.
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912635
Binder, S., Schendzielorz, G., Kohlheyer, D., Grünberger, A., Wiechert, W., Bott, M., and Eggeling, L. (2012).“Metabolite sensors for single-cell isolation of producing bacteria”. Presented at the Metabolic Engineering IX, Biarritz, France.
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912642
Grünberger, A., Frank, P., Probst, C., Wiechert, W., and Kohlheyer, D. (2012).“Single Cell Microfluidics: From Fabrication to Application”. Presented at the Jülich Biotech Day, Jülich, Germany.
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912647
Helfrich, S., Grünberger, A., Kohlheyer, D., Wiechert, W., and Nöh, K. (2012).“Semi-Automated Evaluation of Microbial Observables from High-Throughput Time-lapse Microscopy”. Presented at the German Conference on Bioinformatics 2012, Jena (Germany).
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912767
Grünberger, A., Probst, C., Wiechert, W., and Kohlheyer, D. (2012).“Fermentation at Picoliter Scale: Microfluidics for single cell analysis of prokaryotic production strains”. Presented at the Achema 2012, Frankfurt, Germany.
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912837
Probst, C., Grünberger, A., Wiechert, W., and Kohlheyer, D. (2012).“Screening of Escherichia coli on single-cell level by hyphenating microfluidic picoliter fermentation and optical tweezers”. Presented at the 3rd European Conference on Microfluidics, Heidelberg, Germany.
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912728 OA
Grünberger, A., Paczia, N., Probst, C., Schendzielorz, G., Eggeling, L., Noack, S., Wiechert, W., and Kohlheyer, D. (2012). A disposable picolitre bioreactor for cultivation and investigation of industrially relevant bacteria on the single cell level. Lab on a Chip 12, 2060-2068.
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912747
Scholz, K. E., Okrob, D., Kopka, B., Grünberger, A., Pohl, M., Jaeger, K. - E., and Krauss, U. (2012). Synthesis of Chiral Cyanohydrins by Recombinant Escherichia coli Cells in a Micro-Aqueous Reaction System. Applied and Environmental Microbiology 78, 5025-5027.
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912776
Grünberger, A., Probst., C., Frank, P., Wiechert, W., and Kohlheyer, D. (2012).“Single Cell Analysis of Industrially Relevant Bacterial Strains in Picoliter Environments”. Presented at the EMBL Conference – Microfluidics 2012, Heidelberg, Germany.
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912839
Probst, C., Grünberger, A., Wiechert, W., and Kohlheyer, D. (2012).“Phenotypic Sorting and Analysis of Bacteria Production Strains using Optical Tweezers and Microfluidics”. Presented at the EMBL Conference – Microfluidics 2012, Heidelberg, Germany.
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912841
Nanda, A. M., Grünberger, A., Heyer, A., Helfrich, S., Kohlheyer, D., Nöh, K., and Frunzke, J. (2012).“Dynamics of the SOS response in single cells of Corynebacterium glutamicum”. Presented at the 2nd Molecular Microbiology Meeting Würzburg, Würzburg, Germany.
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2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912639
Probst, C., Grünberger, A., Kohlheyer, D., and Wiechert, W. (2012). Phenotypic Sorting and Analysis of Bacteria ProductionStrains Using Optical Tweezers and Microfluidics. Chemie - Ingenieur - Technik: CIT 84, 1344.
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2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912641
Grünberger, A., Probst, C., Wiechert, W., and Kohlheyer, D. (2012). Femtoliter Growth Channels. Bacteria Long-Term Growth Patterns Analysis on Singel Cell Level. Chemie - Ingenieur - Technik (CIT) 84, 1407.
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2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912646
Grünberger, A., Helfrich, S., Probst, C., Nöh, K., Wiechert, W., and Kohlheyer, D. (2012). “Industrial Biotechnology meets Microfluidics - Disposable high-throughput single cell analysis device for industrially relevant bacterial strains” in Proceedings - µFLU-12, Colin, S. ed. Publications S.H.F. (Paris: SHF).
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912633
Grünberger, A., Probst, C., Wiechert, W., and Kohlheyer, D. (2012).“Picoliter bioreactors for growth heterogeneity studies of industrially relevant bacteria on single cell level”. Presented at the 2nd BioProScale Symposium: Inhomogeneities in large-scale bioprocesses: System biology and process dynamics, Berlin, Germany.
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912638
Mustafi, N., Grünberger, A., Helfrich, S., Kohlheyer, D., Nöh, K., Bott, M., and Frunzke, J. (2012).“A biosensor for the intracellular detection of L-methionine and branched-chain amino acids - Monitoring of amino acid production at the single cell level”. Presented at the 15th International Conference on Biotechnology, Istanbul, Turkey.
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2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912640
Grünberger, A., Probst, C., Wiechert, W., and Kohlheyer, D. (2012). High-Throughput Growth Rate Determination of Bacteria Micro colonies on Single Cell Level. Chemie - Ingenieur - Technik: CIT 84, 1336-1337.
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912645
Kohlheyer, D., Grünberger, A., Probst, C., Frank, P., and Wiechert, W. (2012).“Catch it and batch it: picoliter fermentation at the single cell level”. Presented at the International Workshop on New and Synthetic Bioproduction Systems, Hamburg-Harburg, Germany.
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2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912746
Mustafi, N., Grünberger, A., Kohlheyer, D., Bott, M., and Frunzke, J. (2012). The development and application of a single-cell biosensor for the detection of l-methionine and branched-chain amino acids. Metabolic Engineering 14, 449-457.
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2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912758
Grünberger, A., Probst, C., Binder, S., Ziaee, R., Eggeling, L., Wiechert, W., and Kohlheyer, D. (2012). “Single Cell Trapping and Analysis for Prokaryotic Production Strains in Sub-µm Fluidic Structures” in 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011 (MiroTAS 2011), Landers, J. ed. (Red Hook, NY: Curran).
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912777
Grünberger, A., Probst, C., Wiechert, W., and Kohlheyer, D. (2012).“Towards high-throughput single cell growth optimization and production analysis using picoliter bioreactors”. Presented at the Metabolic Engineering IX 2012, Biarritz, France.
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912838
Frank, P., Probst, C., Grünberger, A., Wiechert, W., and Kohlheyer, D. (2012).““Catch it and Batch it”- Microfluidics single cell batch cultivation utilizing picoliter bioreactors”. Presented at the ProcessNet- Jahrestagung 2012 und 30. DECHEMA Jahrestagung der Biotechnologen, Karlsruhe, Germany.
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912840
Nanda, A. M., Grünberger, A., Heyer, A., Helfrich, S., Kohlheyer, D., Nöh, K., and Frunzke, J. (2012).“Dynamics of the SOS response in single cells of Corynebacterium glutamicum”. Presented at the Microbial Stress: from Molecules to System, Belgirate (VB)/Maggiore Lake, Italy.
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2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912643
Grünberger, A., Helfrich, S., Probst, C., Wiechert, W., Nöh, K., and Kohlheyer, D. (2012). “High-Throughput lineage tree investigations of bacteria microcolonies using arrays of monolayer growth chambers” in Proceedings of The Sixteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2012) (San Diego, California: CBMS).
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2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912778
Grünberger, A., Probst, C., Wiechert, W., and Kohlheyer, D. (2011).“Single Cell Trapping and Analysis for Prokaryotic Production Strains in Sub -µm Fluidic Structures”. Presented at the NanoBioTech-Montreux 2011, Montreux, Switzerland.
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2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912843
Scholz, K. E., Okrob, D., Kopka, B., Grünberger, A., Pohl, M., Jaeger, K. E., and Krauss, U. (2011).“Fluorescence reporters for the analysis of whole cell biocatalysts in non-conventional media”. Presented at the Biotrans 2011, Giardini Naxos (Messina), Italy.
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2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912811
Kohlheyer, D., Grünberger, A., Probst, C., and Wiechert, W. (2011).“Sub-µm Fluidic Structures for Single Cell Trapping and Analysis of Prokaryotic Production Strains”. Presented at the 21st Annual conference of the German Society for Cytometry, Bonn, Germany.
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2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912842
Mustafi, N., Grünberger, A., Kohlheyer, D., Bott, M., and Frunzke, J. (2011).“A biosensor for the intracellular detection of L-methionine and branched-chain amino acids”. Presented at the 5th International Conference on Analysis of Microbial Cells at the Single Cell Level, Caryy-Le-Rouet, France.
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2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912768
Grünberger, A., Probst, C., Wiechert, W., and Kohlheyer, D. (2011).“A continuous picoliter bioreactor for heterogeneity studies of bacteria microcolonies”. Presented at the NanoBioTech-Montreux 2011, Montreux, Switzerland.
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2010 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912812
Blanko, M. A., Grünberger, A., Sahin, E., and Roberts, C. J. (2010).“Protein Interactions from Kirwood-Buff Analysis of Light Scattering and Coarse-Grained Molecular Models”. Presented at the AIChE Annual Meeting, Salt Lake City (UT), USA.
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2009 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912813
Grünberger, A., Stephens, E., and Hankamer, B. (2009).“Media optimization for the microalgae Chamydomonas reinhardtii Stm6 using statistical design”. Presented at the IMB Summer Symposium: A systems Biology approach to biofuel production: From light capture to biodiesel production, Brisbane, Australia.
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