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199 Publikationen

2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912623
Heyer A, Nanda A, Grünberger A, Kohlheyer D, Frunzke J (2013)
Spontaneous prophage induction in Corynebacterium glutamicum.
Presented at the VAAM-Tagung 2013, Bremen, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912630
Kohlheyer D, Grünberger A, Probst C, Krämer C, Eggeling L, Frunzke J, Wiechert W (2013)
Microbial single cell analysis of production strains in microfabricated habitats.
Presented at the DECHEMA-Workshop Microfluidics for Systems Biology and Bioprocess Development, Frankfurt, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912825
Binder D, Grünberger A, Loeschcke A, Probst C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger KE, Drepper T (2013)
Characterization of light-triggered gene expression in E. coli with respect to population and single cell response.
Presented at the Jülich Biotech Day, Jülich, Germany.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912745
Grünberger A, Lai P-K, Blanco MA, Roberts CJ (2013)
Coarse-Grained Modeling of Protein Second Osmotic Virial Coefficients: Sterics and Short-Ranged Attractions.
The Journal of Physical Chemistry B 117(3): 763-770.
PUB | DOI | WoS | PubMed | Europe PMC
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912810
Helfrich S, Grünberger A, Kohlheyer D, Wiechert W, Nöh K (2013)
Analysis of microbial observables on single cell level: Challenges of Cell Clusters for Microscopy-based Image Processing.
Presented at the 9th European Congress of Chemical Engineering (ECCE9)/ 2nd European Congress of Applied Biotechnology (ECAB2), The Hague, Netherlands.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912824
Nanda AM, Heyer A, Grünberger A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2013)
Single-cell dynamics of the SOS response in Corynebacterium glutamicum.
Presented at the Jülich Biotech Day, Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912827
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2013)
Application of a genetically- encoded metabolite sensor for single cell analysis and the development of production strains.
Presented at the Jülich Biotech Day, Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912829
Sachs C, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Automated image analysis pipeline for single cell bacterial growth studies.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912834
Binder D, Grünberger A, Loeschcke A, Probst C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger KE, Drepper T (2013)
Characterization of light-triggered gene expression in E. coli with respect to population and single cell response.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912836
Binder D, Grünberger A, Loeschcke A, Probst C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger KE, Drepper T (2013)
Characterization of light-triggered gene expression in E. coli with respect to population and single cell response.
Presented at the New Approaches and Concepts in Microbiology, Heidelberg, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912603
Grünberger A, Probst C, Unthan S, Krämer C, Paczia N, Noack S, Wiechert W, Kohlheyer D (2013)
Single Cell Bioreactors for Bioprocess Optimization.
Presented at the Jülich Biotech Day 2013, Jülich,Germany.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912606
Hoffmann K, Grünberger A, Lausberg F, Bott M, Eggeling L (2013)
Visualization of Imbalances in Sulfur Assimilation and Synthesis of Sulfur-Containing Amino Acids at the Single-Cell Level.
Applied and environmental microbiology 79(21): 6730-6736.
PUB | DOI | WoS | PubMed | Europe PMC
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912608
Nanda A, Heyer A, Krämer C, Grünberger A, Kohlheyer D, Frunzke J (2013)
SOS-induced spontaneous prophage induction in Corynebacterium glutamicum.
Presented at the Jülich Biotech Day 2013, Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912613
Probst C, Grünberger A, Frunzke J, Wiechert W, Kohlheyer D (2013)
Microfluidic cultivation technology and application: analysing single-microbes under perfect environmental control.
Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912615
Helfrich S, Azzouzi CE, Grünberger A, Wiechert W, Nöh K (2013)
Explorative Analysis of Cell Population Development: Customizable Interactive Lineage Trees.
Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912618
Kohlheyer D, Grünberger A, Probst C, Frunzke J, Wiechert W (2013)
Picoliter fermentation with single bacteria: Learning from the one to unravel the crowd.
Presented at the 2nd International Congress Implementation of Microreactor Technology in Biotechnology, Cavtat, Croatia.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912620
Noack S, Grünberger A, van Ooyen J, Kohlheyer D, Wiechert W (2013)
Increasing biomass productivity of C. glutamicum - new insights from microscale cultivations.
Presented at the 9th European Congress of Chemical Engineering, Den Haag, The Netherlands.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912622
Wiechert W, Kohlheyer D, Noack S, Frunzke J, Mustafi N, Grünberger A (2013)
Picoliter Bioreactors. Learning from Single Cells about Large Scale Processes.
Presented at the Copenhagen Bioscience Conferences, Cell Factories and Biosustainability, Favrholm, Denmark.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912625
Heinrich J, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Single cell growth under constant environmental conditions and defined C sources: A case study for Corynebacterium glutamicum.
Presented at the VAAM-Tagung 2013, Bremen, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912627
Probst C, Frank P, Grünberger A, Wiechert W, Kohlheyer D (2013)
Time lapse microbial single cell analysis in a micro fabricated batch reactor.
Presented at the Single Cell Analysis Europe 2013, Barcelona, Spain.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2614036
Baumgart M, Unthan S, Rückert C, Sivalingam J, Grünberger A, Kalinowski J, Bott M, Noack S, Frunzke J (2013)
Construction of a prophage-free variant of Corynebacterium glutamicum ATCC 13032 - a platform strain for basic research and industrial biotechnology.
Applied and environmental microbiology 79(19): 6006-6015.
PUB | DOI | WoS | PubMed | Europe PMC
 
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912599
Grünberger A, Probst C, Heyer A, Wiechert W, Frunzke J, Kohlheyer D (2013)
Microfluidic Picoliter Bioreactor for Microbial Single-cell Analysis: Fabrication, System Setup, and Operation.
Journal of visualized experiments. Bioengineering 82: UNSP e50560.
PUB | PDF | DOI | WoS
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912602
Grünberger A, Helfrich S, Mustafi N, Probst C, Frunzke J, Nöh K, Wiechert W, Kohlheyer D (2013)
Automated High-Throughput Time-Lapse Microscopy of Bacteria Microcolonies in Parallelized Monolayer Growth Chambers.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications, Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912607
Nanda A, Heyer A, Krämer C, Grünberger A, Kohlheyer D, Frunzke J (2013)
SOS-induced spontaneous prophage induction in Corynebacterium glutamicum.
Presented at the Nikon Symposium on Advanced Imaging in Cell- and Microbiology Technology and Applications, Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912614
Krämer C, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Continuous Non-Invasive Real-Time Viability Measurement of Bacteria on Single Cell Level in Microfluidic Chip Cultures.
Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912619
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Femtoliter chemostat for long-term bacteria growth and production analysis on single cell level.
Presented at the 2nd International Conference Implementation of Microreactor Technology in Biotechnology, Cavtat, Croatia.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912621
Grünberger A, Mustafi N, Probst C, Frunzke J, Wiechert W, Kohlheyer D (2013)
Towards High-Throughput Microbial Single Cell Analysis In Picoliter Bioreactors.
Presented at the 9th European Congress of Chemical Engineering, Den Haag, The Netherlands.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912626
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Femtoliter chemostat for long-term bacteria growth and production analysis on single cell level.
Presented at the Single Cell Analysis Europe 2013, Barcelona, Spain.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912809
Frunzke J, Mahr R, Grünberger A, Mustafi N, Kohlheyer D (2013)
Microbial Metabolite Production – Live in Concert.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912828
Krämer C, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Continuous Non-Invasive Real-Time Viability Measurement of Bacteria on Single Cell Level in Microfluidic Chip Cultures?
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912830
Probst C, Grünberger A, Krämer C, Wiechert W, Kohlheyer D (2013)
Microfluidic single-cell analysis in dynamic environments.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912835
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2013)
Application of a genetically- encoded metabolite sensor for single cell analysis and the development of production strains.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912826
Helfrich S, Azzouzi CE, Grünberger A, Wiechert W, Nöh K (2013)
Exploration and Analysis of cell population development. Customizable interactive lineage trees.
Presented at the Jülich Biotech Day, Jülich, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912833
Nanda AM, Heyer A, Grünberger A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2013)
Single-cell dynamics of the SOS response in Corynebacterium glutamicum.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
PUB
 
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912600
Probst C, Grünberger A, Wiechert W, Kohlheyer D (2013)
Microfluidic growth chambers with optical tweezers for full spatial single-cell control and analysis of evolving microbes.
Journal of microbiological methods 95(3): 470-476.
PUB | DOI | WoS | PubMed | Europe PMC
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912612
Nanda A, Heyer A, Krämer C, Grünberger A, Kohlheyer D, Frunzke J (2013)
SOS-induced spontaneous prophage induction in Corynebacterium glutamicum.
Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912617
Krämer C, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Continuous viability fluorescent staining of growing Corynebacterium glutamicum colonies without sample preparation in an automated microfluidic measurement system.
Presented at the How Deas Is Dead III Conference, Berlin, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912624
Grünberger A, Mustafi N, Probst C, Frunzke J, Wiechert W, Kohlheyer D (2013)
High-throughput Microbial Single Cell analysis in Picoliter Bioreactors.
Presented at the VAAM-Tagung 2013, Bremen, Germany.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912631
Grünberger A, van Ooyen J, Paczia N, Rohe P, Schendzielorz G, Eggeling L, Wiechert W, Kohlheyer D, Noack S (2013)
Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments.
Biotechnology and bioengineering 110(1): 220-228.
PUB | DOI | WoS | PubMed | Europe PMC
 
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912635
Binder S, Schendzielorz G, Kohlheyer D, Grünberger A, Wiechert W, Bott M, Eggeling L (2012)
Metabolite sensors for single-cell isolation of producing bacteria.
Presented at the Metabolic Engineering IX, Biarritz, France.
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912642
Grünberger A, Frank P, Probst C, Wiechert W, Kohlheyer D (2012)
Single Cell Microfluidics: From Fabrication to Application.
Presented at the Jülich Biotech Day, Jülich, Germany.
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912647
Helfrich S, Grünberger A, Kohlheyer D, Wiechert W, Nöh K (2012)
Semi-Automated Evaluation of Microbial Observables from High-Throughput Time-lapse Microscopy.
Presented at the German Conference on Bioinformatics 2012, Jena (Germany).
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912767
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2012)
Fermentation at Picoliter Scale: Microfluidics for single cell analysis of prokaryotic production strains.
Presented at the Achema 2012, Frankfurt, Germany.
PUB
 
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912837
Probst C, Grünberger A, Wiechert W, Kohlheyer D (2012)
Screening of Escherichia coli on single-cell level by hyphenating microfluidic picoliter fermentation and optical tweezers.
Presented at the 3rd European Conference on Microfluidics, Heidelberg, Germany.
PUB
 
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912728
Grünberger A, Paczia N, Probst C, Schendzielorz G, Eggeling L, Noack S, Wiechert W, Kohlheyer D (2012)
A disposable picolitre bioreactor for cultivation and investigation of industrially relevant bacteria on the single cell level.
Lab on a Chip 12(11): 2060-2068.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912747
Scholz KE, Okrob D, Kopka B, Grünberger A, Pohl M, Jaeger K-E, Krauss U (2012)
Synthesis of Chiral Cyanohydrins by Recombinant Escherichia coli Cells in a Micro-Aqueous Reaction System.
Applied and Environmental Microbiology 78(14): 5025-5027.
PUB | DOI | WoS | PubMed | Europe PMC
 
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912776
Grünberger A, Probst. C, Frank P, Wiechert W, Kohlheyer D (2012)
Single Cell Analysis of Industrially Relevant Bacterial Strains in Picoliter Environments.
Presented at the EMBL Conference – Microfluidics 2012, Heidelberg, Germany.
PUB
 
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912839
Probst C, Grünberger A, Wiechert W, Kohlheyer D (2012)
Phenotypic Sorting and Analysis of Bacteria Production Strains using Optical Tweezers and Microfluidics.
Presented at the EMBL Conference – Microfluidics 2012, Heidelberg, Germany.
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912841
Nanda AM, Grünberger A, Heyer A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2012)
Dynamics of the SOS response in single cells of Corynebacterium glutamicum.
Presented at the 2nd Molecular Microbiology Meeting Würzburg, Würzburg, Germany.
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2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912639
Probst C, Grünberger A, Kohlheyer D, Wiechert W (2012)
Phenotypic Sorting and Analysis of Bacteria ProductionStrains Using Optical Tweezers and Microfluidics.
Chemie - Ingenieur - Technik: CIT 84(8): 1344.
PUB | DOI
 

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