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197 Publikationen

2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912808
Metabolite biosensors for single cell analysis and the development of production strains
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2014)
Presented at the 30th Symposium „Mechanisms of gene regulation”, Düsseldorf, Germany.
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912730
Analysis of SOS-Induced Spontaneous Prophage Induction in Corynebacterium glutamicum at the Single-Cell Level
Nanda AM, Heyer A, Kramer C, Grünberger A, Kohlheyer D, Frunzke J (2014)
Journal of Bacteriology 196(1): 180-188.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912766
Picoliter Bioreactors. Learning from Single Cells about Large Scale Processes
Grünberger A (2014)
Presented at the iGEM Meetup, Aachen, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912569
Cage me if you can! Optogenetic bacterial gene regulation using photocaged inducers
Binder D, Grünberger A, Loeschcke A, Probst C, Bier C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger K-E, Drepper T (2014)
Presented at the VAAM Jahrestagung, Dresden, Germany.
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2014 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912571
Microfluidic Single-Cell Analysis Platform for Biotechnological Process Development
Grünberger A, Probst C, Helfrich S, Frunzke J, Noack S, Nöh K, Wiechert W, Kohlheyer D (2014)
In: MicroTAS 2014. San Diego, California: CBM Society: 3 p.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912576
From extracellular Environment to functional phenotype. Quantitative comparison of single cell physiology in static and steady environments
Dusny C, Grünberger A, Wiechert W, Kohlheyer D, Schmid A (2014)
Presented at the 3rd BioProScale Symposium "Inhomogeneities in large-scale bioprocesses. System biology and process dynamics", Berlin, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912583
Picoliter Bioreactors. Learning from Single Cells about Large-Scale Bioprocesses
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2014)
Presented at the 24th Annual conference of the German Society for Cytometry, Dresden, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912586
Microbial Populations on the Microfluidic Analyst's Couch: Approaching Cellular Heterogeneity
Helfrich S, Azzouzi CE, Krämer C, Pfeifer E, Grünberger A, Mustafi N, Wiechert W, Frunzke J, Kohlheyer D, Nöh K (2014)
Presented at the BioImage Informatics 2014, Leuven, Belgium.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912588
Investigating single-cell growth of microbial cell factories: is counting cells enough?
Helfrich S, Grünberger A, Kohlheyer D, Wiechert W, Nöh K (2014)
Presented at the 2nd International Workshop on Image-based Systems Biology, Jena (Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912590
Transcription factor-based biosensor for microbial strain development
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2014)
Presented at the 30th Symposium "Mechanisms of Gene Regulation" of the VAAM study group "Regulation & Signal Transduction in Prokaryotes", Düsseldorf, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2912593
Systematic screening of single-cell growth and production in a picoliter cultivation platform
Grünberger A, Unthan S, Mahr R, Frunzke J, Noack S, Wiechert W, Kohlheyer D (2014)
Chemie Ingenieur Technik 86(9): 1408.
PUB | DOI
 
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912595
Single-cell Bioreactors boost Bioprocess Development: New Insights into Cellular Metabolism
Kohlheyer D, Grünberger A, Probst C, Helfrich S, Frunzke J, Eggeling L, Nöh K, Noack S, Wiechert W (2014)
Presented at the Metabolic Engineering X, Vancouver, Canada.
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2014 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912601
Simple microfluidics for complex organisms: A microfluidic chip System for growth and Morphogenesis studies of filamentous fungi
Grünberger A, Schmitz K, Probst C, Noack S, Wiechert W, Kohlheyer D (2014)
In: 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2013). Red Hook, NY: Curran.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912823
Application of a genetically-encoded metabolite sensor for single cell analysis and development of production strains
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2014)
Presented at the Metabolic engineering X, Vancouver, Canada.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912575
Microfluidics as platform for the spatiotemporal analysis of bacterial populations at single-cell level
Krämer C, Helfrich S, Azzouzi CE, Grünberger A, Pfeifer E, Frunzke J, Wiechert W, Nöh K, Kohlheyer D (2014)
Presented at the International Meeting, Phenotypic heterogeneity and sociobiology of bacterial populations, Irsee, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912582
Microfluidic Single-Cell Cultivation Systems: Versatile Tools for Microbiology
Grünberger A, Probst C, Nanda A, Frunzke J, Wiechert W, Kohlheyer D (2014)
Presented at the 4th Annual Conference of the Association for General and Applied Microbiology, Dresden, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912587
Metabolite biosensors for single cell analysis and the development of production strains
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2014)
Presented at the Gemeinsame Jahrestagung der Deutschen Gesellschaft für Hygiene und Mikrobiologie und der Vereinigung für Allgemeine und Angewandte Mikrobiologie, Dresden, Germany.
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912594
Light-responsive control of bacterial gene Expression: precise triggering of the lac promoter activity using photocaged IPTG
Binder D, Grünberger A, Loeschcke A, Probst C, Bier C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger K-E, Drepper T (2014)
Integrative biology 6(8): 755-765.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912814
Introduction into Microfluidic Single-Cell Analysis
Grünberger A, Probst C (2014)
Presented at the Biology feat, Engineering – SYNBIO – Single Cell Analysis in Microfluidic Devices (Workshop), Jülich, Germany.
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912605
Taking Control over Control: Use of Product Sensing in Single Cells to Remove Flux Control at Key Enzymes in Biosynthesis Pathways
Schendzielorz G, Dippong M, Grünberger A, Kohlheyer D, Yoshida A, Binder S, Nishiyama C, Nishiyama M, Bott M, Eggeling L (2014)
ACS Synthetic Biology 3(1): 21–29.
PUB | DOI | WoS | PubMed | Europe PMC
 
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912573
Application of a Genetically Encoded Biosensor for Live Cell Imaging of L-Valine Production in Pyruvate Dehydrogenase Complex-Deficient Corynebacterium glutamicum Strains
Mustafi N, Grünberger A, Mahr R, Helfrich S, Nöh K, Blombach B, Kohlheyer D, Frunzke J (2014)
PLoS one 9(1): e85731.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912580
Quantitative Physiology of Single Cells for Linking Phenotype and Environment
Dusny C, Grünberger A, Rosenthal K, Wiechert W, Schmid A (2014)
Presented at the 24th Annual Conference of the German Society for Flow Cytometry, Dresden, Germany.
PUB
 
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912585
Robust Automated Image Analysis of Mother Machine Microfluidic Growth Devices
Sachs CC, Grünberger A, Wiechert W, Nöh K, Kohlheyer D (2014)
Presented at the BioImage Informatics 2014, Leuven, Belgium.
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2014 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2912592
Optimizing growth performance of Corynebacterium glutamicum at the single-cell level
Weber S, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2014)
Chemie Ingenieur Technik 88(9): 1414.
PUB | DOI
 
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912597
Single-cell microfluidics: opportunity for bioprocess development
Grünberger A, Wiechert W, Kohlheyer D (2014)
Current opinion in biotechnology 29: 15-23.
PUB | DOI | WoS | PubMed | Europe PMC
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912825
Characterization of light-triggered gene expression in E. coli with respect to population and single cell response
Binder D, Grünberger A, Loeschcke A, Probst C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger KE, Drepper T (2013)
Presented at the Jülich Biotech Day, Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912604
Application of a genetically encoded biosensor for single cell analysis and strain development of production strains
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2013)
Presented at the New concepts and approaches in microbiology, Heidelberg, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912609
Single-cell Dynamics of the SOS Response in Corynebacterium glutamicum
Nanda A, Heyer A, Grünberger A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2013)
Presented at the Bacterial Networks, Pultusk, Poland.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912611
Polydimethylsiloxane (PDMS) Sub-Micron Traps for Single-Cell Analysis of Bacteria
Probst C, Grünberger A, Wiechert W, Kohlheyer D (2013)
Micromachines 4(4): 357-369.
PUB | PDF | DOI | WoS
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912623
Spontaneous prophage induction in Corynebacterium glutamicum
Heyer A, Nanda A, Grünberger A, Kohlheyer D, Frunzke J (2013)
Presented at the VAAM-Tagung 2013, Bremen, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912630
Microbial single cell analysis of production strains in microfabricated habitats
Kohlheyer D, Grünberger A, Probst C, Krämer C, Eggeling L, Frunzke J, Wiechert W (2013)
Presented at the DECHEMA-Workshop Microfluidics for Systems Biology and Bioprocess Development, Frankfurt, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912810
Analysis of microbial observables on single cell level: Challenges of Cell Clusters for Microscopy-based Image Processing
Helfrich S, Grünberger A, Kohlheyer D, Wiechert W, Nöh K (2013)
Presented at the 9th European Congress of Chemical Engineering (ECCE9)/ 2nd European Congress of Applied Biotechnology (ECAB2), The Hague, Netherlands.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912824
Single-cell dynamics of the SOS response in Corynebacterium glutamicum
Nanda AM, Heyer A, Grünberger A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2013)
Presented at the Jülich Biotech Day, Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912827
Application of a genetically- encoded metabolite sensor for single cell analysis and the development of production strains
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2013)
Presented at the Jülich Biotech Day, Jülich, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912829
Automated image analysis pipeline for single cell bacterial growth studies
Sachs C, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912834
Characterization of light-triggered gene expression in E. coli with respect to population and single cell response
Binder D, Grünberger A, Loeschcke A, Probst C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger KE, Drepper T (2013)
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912836
Characterization of light-triggered gene expression in E. coli with respect to population and single cell response
Binder D, Grünberger A, Loeschcke A, Probst C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger KE, Drepper T (2013)
Presented at the New Approaches and Concepts in Microbiology, Heidelberg, Germany.
PUB
 
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912745
Coarse-Grained Modeling of Protein Second Osmotic Virial Coefficients: Sterics and Short-Ranged Attractions
Grünberger A, Lai P-K, Blanco MA, Roberts CJ (2013)
The Journal of Physical Chemistry B 117(3): 763-770.
PUB | DOI | WoS | PubMed | Europe PMC
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912603
Single Cell Bioreactors for Bioprocess Optimization
Grünberger A, Probst C, Unthan S, Krämer C, Paczia N, Noack S, Wiechert W, Kohlheyer D (2013)
Presented at the Jülich Biotech Day 2013, Jülich,Germany.
PUB
 
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912606
Visualization of Imbalances in Sulfur Assimilation and Synthesis of Sulfur-Containing Amino Acids at the Single-Cell Level
Hoffmann K, Grünberger A, Lausberg F, Bott M, Eggeling L (2013)
Applied and environmental microbiology 79(21): 6730-6736.
PUB | DOI | WoS | PubMed | Europe PMC
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912608
SOS-induced spontaneous prophage induction in Corynebacterium glutamicum
Nanda A, Heyer A, Krämer C, Grünberger A, Kohlheyer D, Frunzke J (2013)
Presented at the Jülich Biotech Day 2013, Jülich, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912613
Microfluidic cultivation technology and application: analysing single-microbes under perfect environmental control
Probst C, Grünberger A, Frunzke J, Wiechert W, Kohlheyer D (2013)
Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912615
Explorative Analysis of Cell Population Development: Customizable Interactive Lineage Trees
Helfrich S, Azzouzi CE, Grünberger A, Wiechert W, Nöh K (2013)
Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912618
Picoliter fermentation with single bacteria: Learning from the one to unravel the crowd
Kohlheyer D, Grünberger A, Probst C, Frunzke J, Wiechert W (2013)
Presented at the 2nd International Congress Implementation of Microreactor Technology in Biotechnology, Cavtat, Croatia.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912620
Increasing biomass productivity of C. glutamicum - new insights from microscale cultivations
Noack S, Grünberger A, van Ooyen J, Kohlheyer D, Wiechert W (2013)
Presented at the 9th European Congress of Chemical Engineering, Den Haag, The Netherlands.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912622
Picoliter Bioreactors. Learning from Single Cells about Large Scale Processes
Wiechert W, Kohlheyer D, Noack S, Frunzke J, Mustafi N, Grünberger A (2013)
Presented at the Copenhagen Bioscience Conferences, Cell Factories and Biosustainability, Favrholm, Denmark.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912625
Single cell growth under constant environmental conditions and defined C sources: A case study for Corynebacterium glutamicum
Heinrich J, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Presented at the VAAM-Tagung 2013, Bremen, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912627
Time lapse microbial single cell analysis in a micro fabricated batch reactor
Probst C, Frank P, Grünberger A, Wiechert W, Kohlheyer D (2013)
Presented at the Single Cell Analysis Europe 2013, Barcelona, Spain.
PUB
 
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2614036
Construction of a prophage-free variant of Corynebacterium glutamicum ATCC 13032 - a platform strain for basic research and industrial biotechnology
Baumgart M, Unthan S, Rückert C, Sivalingam J, Grünberger A, Kalinowski J, Bott M, Noack S, Frunzke J (2013)
Applied and environmental microbiology 79(19): 6006-6015.
PUB | DOI | WoS | PubMed | Europe PMC
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912809
Microbial Metabolite Production – Live in Concert
Frunzke J, Mahr R, Grünberger A, Mustafi N, Kohlheyer D (2013)
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
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