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195 Publikationen

2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2935496
A microfluidic photobioreactor for simultaneous observation and cultivation of single microalgal cells or cell aggregates.
Westerwalbesloh C, Brehl C, Weber S, Probst C, Widzgowski J, Grünberger A, Pfaff C, Nedbal L, Kohlheyer D (2019)
PloS one 14(4).
PUB | DOI | WoS | PubMed | Europe PMC
 
2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2933358
Heterogeneity Studies of Mammalian Cells for Bioproduction. From Tools to Application
Schmitz J, Noll T, Grünberger A (2019)
Trends in Biotechnology.
PUB | DOI | WoS | PubMed | Europe PMC
 
2019 | Zeitschriftenaufsatz | E-Veröff. vor dem Druck | PUB-ID: 2935887
Segregostat: a novel concept to control phenotypic diversification dynamics on the example of Gram-negative bacteria.
Sassi H, Nguyen TM, Telek S, Gosset G, Grünberger A, Delvigne F (2019)
Microbial biotechnology.
PUB | DOI | PubMed | Europe PMC
 
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2935495
Reproduction of Large-Scale Bioreactor Conditions on Microfluidic Chips.
Ho P, Westerwalbesloh C, Kaganovitch E, Grünberger A, Neubauer P, Kohlheyer D, Lieres E von (2019)
Microorganisms 7(4).
PUB | DOI | WoS | PubMed | Europe PMC
 
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2935584
When a single lineage is not enough: Uncertainty-Aware Tracking for spatio-temporal live-cell image analysis
Theorell A, Seiffarth J, Grünberger A, Noeh K (2019)
BIOINFORMATICS 35(7): 1221-1228.
PUB | DOI | WoS | PubMed | Europe PMC
 
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2934065
Tailoring the properties of (catalytically)-active inclusion bodies.
Jager VD, Kloss R, Grünberger A, Seide S, Hahn D, Karmainski T, Piqueray M, Embruch J, Longerich S, Mackfeld U, Jaeger K-E, et al. (2019)
Microbial cell factories 18(1).
PUB | DOI | WoS | PubMed | Europe PMC
 
2019 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2932955
A microfluidic co-cultivation platform to investigate microbial interactions at defined microenvironments
Burmeister A, Hilgers F, Langner A, Westerwalbesloh C, Kerkhoff Y, Tenhaef N, Drepper T, Kohlheyer D, von Lieres E, Noack S, Grünberger A (2019)
LAB ON A CHIP 19(1): 98-110.
PUB | DOI | WoS | PubMed | Europe PMC
 
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2919078
Quantitative modelling of nutrient-limited growth of bacterial colonies in microfluidic cultivation
Hornung R, Grünberger A, Westerwalbesloh C, Kohlheyer D, Gompper G, Elgeti J (2018)
JOURNAL OF THE ROYAL SOCIETY INTERFACE 15(139): 11.
PUB | DOI | WoS | PubMed | Europe PMC
 
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2932764
Germination and Growth Analysis of Streptomyces lividans at the Single-Cell Level Under Varying Medium Compositions
Koepff J, Sachs CC, Wiechert W, Kohlheyer D, Noeh K, Oldiges M, Grünberger A (2018)
FRONTIERS IN MICROBIOLOGY 9: 2680.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
2018 | Konferenzbeitrag | PUB-ID: 2933363
Towards Microfluidic Single-Cell Cultivation of Mammalian Cell Lines
Schmitz J, Noll T, Grünberger A (2018)
Presented at the Young Scientist Cell Culture Biotechnology Retreat, Laupheim.
PUB
 
2018 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2933359
Towards dynamic single-cell cultivation systems for industrially relevant mammalian cell lines
Schmitz J, Kerkhoff Y, Noll T, Kohlheyer D, Grünberger A (2018)
Presented at the BioProcessing Days 2018, Recklinghausen.
PUB
 
2018 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2933362
Dynamic microfluidical single-cell cultivation of mammalian cell lines. From experiment to analysis
Schmitz J, Kerkhoff Y, Noll T, Grünberger A (2018)
Presented at the CeBiTec Symposium 2018, Bielefeld.
PUB
 
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2932765
Tailor-made catalytically active inclusion bodies for different applications in biocatalysis
Kloss R, Karmainski T, Jaeger VD, Hahn D, Grünberger A, Baumgart M, Krauss U, Jaeger K-E, Wiechert W, Pohl M (2018)
CATALYSIS SCIENCE & TECHNOLOGY 8(22): 5816-5826.
PUB | DOI | WoS
 
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2932416
Selective Pressure for Biofilm Formation in Bacillus subtilis: Differential Effect of Mutations in the Master Regulator SinR on Bistability
Kampf J, Gerwig J, Kruse K, Cleverley R, Dormeyer M, Grünberger A, Kohlheyer D, Commichau FM, Lewis RJ, Stuelke J (2018)
mBio 9(5): e01464-18.
PUB | DOI | WoS | PubMed | Europe PMC
 
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2930515
Natural biocide cocktails: Combinatorial antibiotic effects of prodigiosin and biosurfactants
Hage-Huelsmann J, Grünberger A, Thies S, Santiago-Schuebel B, Klein AS, Pietruszka J, Binder D, Hilgers F, Domroese A, Drepper T, Kohlheyer D, et al. (2018)
PLOS ONE 13(7): e0200940.
PUB | DOI | WoS | PubMed | Europe PMC
 
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920273
Catalytically active inclusion bodies of L-lysine decarboxylase from E. coli for 1,5-diaminopentane production
Kloss R, Limberg MH, Mackfeld U, Hahn D, Grünberger A, Jaeger VD, Krauss U, Oldiges M, Pohl M (2018)
SCIENTIFIC REPORTS 8: 11.
PUB | DOI | WoS | PubMed | Europe PMC
 
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2920685
Inheritance of Cell-Cycle Duration in the Presence of Periodic Forcing
Mosheiff N, Martins BMC, Pearl-Mizrahi S, Grünberger A, Helfrich S, Mihalcescu I, Kohlheyer D, Locke JCW, Glass L, Balaban NQ (2018)
PHYSICAL REVIEW X 8(2): 15.
PUB | DOI | WoS
 
2018 | Bielefelder E-Dissertation | PUB-ID: 2919683 PUB | PDF
 
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2931505
A Synthetic Reaction Cascade Implemented by Colocalization of Two Proteins within Catalytically Active Inclusion Bodies
Jaeger VD, Lamm R, Kloss R, Kaganovitch E, Grünberger A, Pohl M, Buechs J, Jaeger K-E, Krauss U (2018)
ACS SYNTHETIC BIOLOGY 7(9): 2282-2295.
PUB | DOI | WoS | PubMed | Europe PMC
 
2018 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2919063
Visualization of tandem repeat mutagenesis in Bacillus subtilis
Dormeyer M, Lentes S, Ballin P, Wilkens M, Klumpp S, Kohlheyer D, Stannek L, Grünberger A, Commichau FM (2018)
DNA REPAIR 63: 10-15.
PUB | DOI | WoS | PubMed | Europe PMC
 
2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912738
Coarse-graining bacteria colonies for modelling critical solute distributions in picolitre bioreactors for bacterial studies on single-cell level
Westerwalbesloh C, Grünberger A, Wiechert W, Kohlheyer D, von Lieres E (2017)
Microbial Biotechnology 10(4): 845-857.
PUB | DOI | WoS | PubMed | Europe PMC
 
2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2916519
Homogenizing bacterial cell factories: Analysis and engineering of phenotypic heterogeneity
Binder D, Drepper T, Jaeger K-E, Delvigne F, Wiechert W, Kohlheyer D, Grünberger A (2017)
METABOLIC ENGINEERING 42: 145-156.
PUB | DOI | WoS | PubMed | Europe PMC
 
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912503
Picoliter bioreactors for microbial consortia: From proof of concept to first application
Rudat A, Wiechert W, Kohlheyer D, Grünberger A (2017)
Presented at the Himmelfahrtstagung 2017: Models for Developing and Optimising Biotech Production, Neu-Ulm, Germany.
PUB
 
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912508
Microfluidic heterogeneity analysis of fluorescence-based gene expression of industrially relevant production strains on single-cell level
Burmeister A, Bitzenhofer NL, Grünberger A, Binder D, Drepper T, Wiechert W, Kohlheyer D (2017)
Presented at the BioProcessing Days 2017, Recklinghausen, Germany.
PUB
 
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912771
Microfluidic single-cell (co-)cultivation: Exploring the next dimension
Rudat A, Noack S, Wiechert W, Kohlheyer D, Grünberger A (2017)
Presented at the Data-driven Biotechnology - bench, bioreactor and bedside, Copenhagen, Denmark.
PUB
 
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912759
Microfluidic Single-Cell Cultivation: A key for next generation bioprocess development?
Grünberger A (2017)
Presented at the FFBiotech Symposium - Innovative approaches in bioreactors design and operation, Lille, France.
PUB
 
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912505
Microfluidic single-cell cultivation of S. lividans: Uncovering heterogeneity in filamentous growth
Sachs CC, Koepff J, Kohlheyer D, Wiechert W, Oldiges M, Nöh K, Grünberger A (2017)
Presented at the DECHEMA-Tagung "Systems Biology meets Synthetic Biology", Frankfurt, Germany.
PUB
 
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912502
Functionally-active protein aggregates - towards the realization of an enzyme cascade in catalytically-active inclusion bodies
Jäger VD, Longerich S, Dietrich M, Kloss R, Grünberger A, Pohl M, Jaeger K-E, Krauss U (2017)
Presented at the BioTrans 2017, Budapest, Hungary.
PUB
 
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912507
Spatiotemporal analysis of synthetic microbial communities at the single-cell level in microfluidic interaction compartments
Rudat A, Wiechert W, Kohlheyer D, Grünberger A (2017)
Presented at the 6th International Conference on Microbial Communication for Young Scientists, Jena, Germany.
PUB
 
2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912521
Real-time monitoring of fungal growth and morphogenesis at single-cell resolution
Grünberger A, Schöler K, Probst C, Kornfeld G, Hardiman T, Wiechert W, Kohlheyer D, Noack S (2017)
Engineering in life sciences 17(1): 86–92.
PUB | DOI | WoS
 
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912501
Catalytically active inclusion bodies. A novel carrier-free Enzyme Immobilisation method
Kloss R, Limberg M, Jäger VD, Mackfeld U, Karmainski T, Grünberger A, Krauss U, Pohl M (2017)
Presented at the BioTrans 2017, Budapest, Hungary.
PUB
 
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912506
Integrated High-Throughput Platform for Microfluidic Live-Cell Analysis with Feed-Back Eyperimentation
Sachs CC, Grünberger A, Probst C, Wiechert W, Kohlheyer D, Nöh K (2017)
Presented at the DECHEMA-Tagung "Systems Biology meets Synthetic Biology", Frankfurt, Germany.
PUB
 
2017 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912518
Microfluidic device for control and sensing of dynamic oxygen levels during cell cultivation
Kaganovitch E, Krischer M, Probst C, Grünberger A, Zunic E, Freier C, Wiechert W, Kohlheyer D (2017)
In: 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016). Red Hook, NY: Curran Associates, Inc.: 355-356.
PUB
 
2017 | Sammelwerksbeitrag | Veröffentlicht | PUB-ID: 2912520
Application of Mini- and Micro-Bioreactors for Microbial Bioprocesses
Ladner T, Grünberger A, Probst C, Kohlheyer D, Büchs J, Delvigne F (2017)
In: Current Developments in Biotechnology and Bioengineering. Larroche C, Sanromán MÁ, Du G, Pandey A (Eds); Amsterdam: Elsevier: 433-461.
PUB | DOI
 
2017 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912737
Taking control over microbial populations: Current approaches for exploiting biological noise in bioprocesses
Delvigne F, Baert J, Sassi H, Fickers P, Grünberger A, Dusny C (2017)
Biotechnology Journal 12(7): 1600549.
PUB | DOI | WoS | PubMed | Europe PMC
 
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912504
Models for Developing and Optimizing Microscale Bacteria Cultivation
Westerwalbesloh C, Grünberger A, Wiechert W, Kohlheyer D, von Lieres E (2017)
Presented at the Himmelfahrtstagung 2017: Models for Developing and Optimising Biotech Production, Neu-Ulm, Germany.
PUB
 
2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912509
Microfluidic cultivation chamber for the investigation of synthetic microbial co-cultures on single-cell level: From the development to first application
Rudat A, Wiechert W, Kohlheyer D, Grünberger A (2017)
Presented at the BioProcessing Days 2017, Recklinghausen, Germany.
PUB
 
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912522
Image-Based Single Cell Profiling: High-Throughput Processing of Mother Machine Experiments
Sachs CC, Grünberger A, Helfrich S, Probst C, Wiechert W, Kohlheyer D, Nöh K (2016)
PLoS one 11(9): e0163453 -.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912514
Comparative Single-Cell Analysis of Different E. coli Expression Systems during Microfluidic Cultivation
Binder D, Probst C, Grünberger A, Hilgers F, Loeschcke A, Jaeger K-E, Kohlheyer D, Drepper T (2016)
PLoS one 11(8): e0160711.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912820
Combinatorial antibiotic effects of natural biocide cocktails
Hage-Hülsmann J, Grünberger A, Thies S, Domröse A, Klein A, Binder D, Hilgers F, Kohlheyer D, Pietruszka J, Jaeger K-E, Drepper T, et al. (2016)
Presented at the IV International Conference on Antimicrobial Research, Malaga, Spain.
PUB
 
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912527
Microfluidic single-cell cultivation: Is small the new beautiful?
Grünberger A (2016)
Presented at the 6th International Bielefeld-CeBiTec Research Conference: Advances in Industrial Biotechnology: New Techniques, Substrates and Products for Bioprocesses, Bielefeld, Germany.
PUB
 
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912534
Single-cell microfluidics for bioprocess development
Grünberger A (2016)
Presented at the GreenWin Conferences “Green Chemistry and White Biotechnology", Gembloux, Belgium.
PUB
 
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912539
Nutrient distribution in perfusion based picoliter bioreactors
Westerwalbesloh C, Grünberger A, Stute B, Weber S, Wiechert W, Kohlheyer D, von Lieres E (2016)
Presented at the 4th BioProScale Symposium "Bioprocess intensification through process analytical technology (PAT) and quality by design (QbD)", Berlin, Germany.
PUB
 
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912803
Employing photocaged carbohydrates in light-controlled cell factories for synthetic bio(techno)logy and single cell applications
Binder D, Bier C, Grünberger A, Hilgers F, Loeschcke A, Kohlheyer D, Pietruszka J, Jaeger KE, Drepper T (2016)
Presented at the Annual Conference of the Association for General and Applied Microbiology (VAAM),, Jena, Germany.
PUB
 
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912761
Microfluidic single-cell bioreactors. Introduction, application and future perspectives
Grünberger A (2016)
Presented at the LCSB Biannual Minisymposia in Modelling/Automation/Microfluidics at the University of Luxembourg, Esch-sur-Alzette, Luxembourg.
PUB
 
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912512
Sugar Based Caged Compounds for Biotechnological Synthetic Biological Applications
Bier C, Binder D, Grünberger A, Drobietz D, Hage-Hülsmann J, Kohlheyer D, Löschcke A, Jaeger K-E, Drepper T, Pietruszka J (2016)
Presented at the 26th IUPAC Symposium on Photochemistry, Osaka, Japan.
PUB
 
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912524
Microfluidic cultivation of the microalgae Chlorella sorokiniana on single-cell level at defined environments
Brehl C, Grünberger A, Probst C, Pfaff C, Wiechert W, Behrendt D, Kohlheyer D (2016)
Presented at the 9. DECHEMA Bundesalgenstammtisch, Jülich, Germany.
PUB
 
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912529
Microbial metabolic state diagrams: Using microfluidic single-cell cultivation to predict bacterial gene expresssion
Grünberger A, Steffens I, Binder D, Drepper T, Wiechert W, Kohlheyer D (2016)
Presented at the EMBL Conference Microfluidics, Heidelberg, Germany.
PUB
 
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912531
Modeling inhomogeneities across cultivation chamber arrays in single-cell cultivation devices
Westerwalbesloh C, Grünberger A, Kohlheyer D, von Lieres E (2016)
Presented at the EMBL Conference Microfluidics, Heidelberg (Germany.
PUB
 
2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912536
An integrated platform for dynamic microfluidic experimentation with single-cell resolution
Sachs CC, Probst C, Grünberger A, Wiechert W, Frunzke J, Kohlheyer D, Nöh K (2016)
Presented at the DECHEMA-Tagung 'Single Cell Technologies 2016', Frankfurt, Germany.
PUB
 

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