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199 Publikationen

2017 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912509
Rudat, A., Wiechert, W., Kohlheyer, D., and Grünberger, A. (2017).“Microfluidic cultivation chamber for the investigation of synthetic microbial co-cultures on single-cell level: From the development to first application”. Presented at the BioProcessing Days 2017, Recklinghausen, Germany.
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912522
Sachs, C. C., Grünberger, A., Helfrich, S., Probst, C., Wiechert, W., Kohlheyer, D., and Nöh, K. (2016). Image-Based Single Cell Profiling: High-Throughput Processing of Mother Machine Experiments. PLoS one 11:e0163453 -.
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912514
Binder, D., Probst, C., Grünberger, A., Hilgers, F., Loeschcke, A., Jaeger, K. - E., Kohlheyer, D., and Drepper, T. (2016). Comparative Single-Cell Analysis of Different E. coli Expression Systems during Microfluidic Cultivation. PLoS one 11:e0160711.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912527
Grünberger, A. (2016).“Microfluidic single-cell cultivation: Is small the new beautiful?”. Presented at the 6th International Bielefeld-CeBiTec Research Conference: Advances in Industrial Biotechnology: New Techniques, Substrates and Products for Bioprocesses, Bielefeld, Germany.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912534
Grünberger, A. (2016).“Single-cell microfluidics for bioprocess development”. Presented at the GreenWin Conferences “Green Chemistry and White Biotechnology", Gembloux, Belgium.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912539
Westerwalbesloh, C., Grünberger, A., Stute, B., Weber, S., Wiechert, W., Kohlheyer, D., and von Lieres, E. (2016).“Nutrient distribution in perfusion based picoliter bioreactors”. Presented at the 4th BioProScale Symposium "Bioprocess intensification through process analytical technology (PAT) and quality by design (QbD)", Berlin, Germany.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912820
Hage-Hülsmann, J., Grünberger, A., Thies, S., Domröse, A., Klein, A., Binder, D., Hilgers, F., Kohlheyer, D., Pietruszka, J., Jaeger, K. - E., et al. (2016).“Combinatorial antibiotic effects of natural biocide cocktails”. Presented at the IV International Conference on Antimicrobial Research, Malaga, Spain.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912761
Grünberger, A. (2016).“Microfluidic single-cell bioreactors. Introduction, application and future perspectives”. Presented at the LCSB Biannual Minisymposia in Modelling/Automation/Microfluidics at the University of Luxembourg, Esch-sur-Alzette, Luxembourg.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912803
Binder, D., Bier, C., Grünberger, A., Hilgers, F., Loeschcke, A., Kohlheyer, D., Pietruszka, J., Jaeger, K. E., and Drepper, T. (2016).“Employing photocaged carbohydrates in light-controlled cell factories for synthetic bio(techno)logy and single cell applications”. Presented at the Annual Conference of the Association for General and Applied Microbiology (VAAM),, Jena, Germany.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912512
Bier, C., Binder, D., Grünberger, A., Drobietz, D., Hage-Hülsmann, J., Kohlheyer, D., Löschcke, A., Jaeger, K. - E., Drepper, T., and Pietruszka, J. (2016).“Sugar Based Caged Compounds for Biotechnological Synthetic Biological Applications”. Presented at the 26th IUPAC Symposium on Photochemistry, Osaka, Japan.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912524
Brehl, C., Grünberger, A., Probst, C., Pfaff, C., Wiechert, W., Behrendt, D., and Kohlheyer, D. (2016).“Microfluidic cultivation of the microalgae Chlorella sorokiniana on single-cell level at defined environments”. Presented at the 9. DECHEMA Bundesalgenstammtisch, Jülich, Germany.
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2016 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2912526
Westerwalbesloh, C., Grünberger, A., Wiechert, W., Kohlheyer, D., and von Lieres, E. (2016). Comparison of different cultivation chamber designs for microfluidic bioreactors. Chemie Ingenieur Technik 88, 1390.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912529
Grünberger, A., Steffens, I., Binder, D., Drepper, T., Wiechert, W., and Kohlheyer, D. (2016).“Microbial metabolic state diagrams: Using microfluidic single-cell cultivation to predict bacterial gene expresssion”. Presented at the EMBL Conference Microfluidics, Heidelberg, Germany.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912531
Westerwalbesloh, C., Grünberger, A., Kohlheyer, D., and von Lieres, E. (2016).“Modeling inhomogeneities across cultivation chamber arrays in single-cell cultivation devices”. Presented at the EMBL Conference Microfluidics, Heidelberg (Germany.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912536
Sachs, C. C., Probst, C., Grünberger, A., Wiechert, W., Frunzke, J., Kohlheyer, D., and Nöh, K. (2016).“An integrated platform for dynamic microfluidic experimentation with single-cell resolution”. Presented at the DECHEMA-Tagung 'Single Cell Technologies 2016', Frankfurt, Germany.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912538
Steffens, I., Grünberger, A., Binder, D., Drepper, T., Wiechert, W., and Kohlheyer, D. (2016).“Bacterial phase diagrams. Analyzing and predicting cell-to-cell heterogeneity of microbial gene expression”. Presented at the 4th BioProScale Symposium "Bioprocess intensification through process analytical technology (PAT) and quality by design (QbD)", Berlin (Germany).
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912540
Grünberger, A., Steffens, I., Binder, D., Drepper, T., Wiechert, W., and Kohlheyer, D. (2016).“Bacterial phase diagrams – Using engineering concepts to predict cell-to-cell heterogeneity of microbial gene expression”. Presented at the Jahrestagung 2016 der Vereinigung für Allgemeine und Angewandte Mikrobiologie, Jena, Germany.
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2016 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912552
Probst, C., Freier, C., Mahr, R., Grünberger, A., Helfrich, S., Wiechert, W., Nöh, K., Frunzke, J., and Kohlheyer, D. (2016). “Closing the gap between microfluidic single-cell analysis and bioprocess development for microbial organisms” in 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015) (Red Hook, NY: Curran Associates, Inc.), 537-539.
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912513
Kusen, P. M., Wandrey, G., Probst, C., Grünberger, A., Holz, M., Meyer zu Berstenhorst, S., Kohlheyer, D., Büchs, J., and Pietruszka, J. (2016). Optogenetic Regulation of Tunable Gene Expression in Yeast Using Photo-Labile Caged Methionine. ACS chemical biology 11, 2915-2922.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912525
Burmeister, A., Bitzenhofer, N. L., Grünberger, A., Binder, D., Drepper, T., and Wiechert, W. (2016).“Microfluidic heterogeneity analysis of fluorescence-based gene expression of industrially relevant production strains on single-cell level”. Presented at the 18. Heiligenstädter Kolloquium „Technische Systeme für die Lebenswissenschaften, Heiligenstadt, Germany.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912532
Westerwalbesloh, C., Grünberger, A., Stute, B., Weber, S., Kohlheyer, D., and von Lieres, E. (2016).“Characterizing substrate availability within microfluidic tools employed for the analysis of genetically modified single cells”. Presented at the 1. International Conference on Molecular Interaction Engineering (MIE), Karlsruhe, Germany.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912537
Grünberger, A., Wiechert, W., and Kohlheyer, D. (2016).“Bioprocesses under magnification. Learning from single cells about large-scale processes”. Presented at the 4th BioProScale Symposium "Bioprocess intensification through process analytical technology (PAT) and quality by design (QbD)", Berlin, Germany.
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912544
Binder, D., Bier, C., Grünberger, A., Drobietz, D., Hage-Hülsmann, J., rey, G., Büchs, J., Kohlheyer, D., Loeschcke, A., Wiechert, W., et al. (2016). Photocaged Arabinose - A Novel Optogenetic Switch for Rapid and Gradual Control of Microbial Gene Expression. ChemBioChem 17, 296-299.
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912739
Li, S., Jendresen, C. B., Grünberger, A., Ronda, C., Jensen, S. I., Noack, S., and Nielsen, A. T. (2016). Enhanced protein and biochemical production using CRISPRi-based growth switches. Metabolic Engineering 38, 274-284.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912760
Grünberger, A. (2016).“Picoliter bioreactors for microbial consortia: A novel concept to investigate microbial interactions at the single-cell level”. Presented at the SynComBio Workshop “Applications of synthetic microbial communities in bioeconomy", Düsseldorf, Germany.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912772
Grünberger, A., Sachs, C., Kohlheyer, D., Wiechert, W., and Nöh, K. (2016).“Spatio-temporal analysis of bacterial populations at single-cell level”. Presented at the IBG Modelling Workshop, Jülich, Germany.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912511
Bier, C., Binder, D., Grünberger, A., Drobietz, D., Kohlheyer, D., Löschcke, A., Jaeger, K. - E., Drepper, T., and Pietruszka, J. (2016).“Photocaged Carbohydrates: Versatile Tools for Biotechnological Applications”. Presented at the 18th International Conference on Photochemistry, Paris, France.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912523
Brehl, C., Grünberger, A., Probst, C., Pfaff, C., Wiechert, W., Behrendt, D., and Kohlheyer, D. (2016).“Microfluidic cultivation of the microalgae Chlorella sorokiniana on single-cell level at defined environments”. Presented at the ProcessNet 2016, Aachen, Germany.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912530
Kaganovitch, E., Probst, C., Westerwalbesloh, C., Grünberger, A., Wiechert, W., and Kohlheyer, D. (2016).“Single-cell analysis of E. coli in microfluidic batch reactors”. Presented at the EMBL Conference Microfluidics, Heidelberg (Germany.
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2016 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912535
Grünberger, A., Steffens, I., Binder, D., Drepper, T., Wiechert, W., and Kohlheyer, D. (2016).“Bacterial phase diagrams: A novel concept to predict and control bacterial gene expression”. Presented at the DECHEMA-Himmelfahrtstagung: New Frontiers for Biotech Processes, Koblenz, Germany.
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2016 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2904866
Binder, D., Frohwitter, J., Mahr, R., Bier, C., Grünberger, A., Loeschcke, A., Peters-Wendisch, P., Kohlheyer, D., Pietruszka, J., Frunzke, J., et al. (2016). Light-controlled cell factories – Employing photocaged IPTG for light-mediated optimization of lac-based gene expression and (+)-valencene biosynthesis in Corynebacterium glutamicum. Appl Environ Microbiol 82, 6141-6149.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912554
Krämer, C. E. M., Singh, A., Helfrich, S., Grünberger, A., Wiechert, W., Nöh, K., and Kohlheyer, D. (2015). Non-Invasive Microbial Metabolic Activity Sensing at Single Cell Level by Perfusion of Calcein Acetoxymethyl Ester. PLoS one 10:e0141768.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912541
Binder, D., Bier, C., Grünberger, A., Loeschcke, A., Kohlheyer, D., Pietruszka, J., Jaeger, K. - E., and Drepper, T. (2015).“Light-controlled cell factories - Employing optogenetic plug-and-play expression modules based on photocaged carbohydrates for synthetic bio(techno)logy and single cell applications”. Presented at the ESP Photobiology conference, Aveiro, Portugal.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912546
Grünberger, A., Wiechert, W., and Kohlheyer, D. (2015).“Single-cell microfluidics: A key technology to understand life at environmental defined conditions”. Presented at the Kick-off Konferenz: Leben? - Eine neue Förderinitiative stellt sich vor, Hannover, Germany.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912560
Zunic, E., Schechtel, A., Probst, C., Grünberger, A., Freier, C., Seibold, G., Wiechert, W., and Kohlheyer, D. (2015).“Dynamic environmental control in microfluidic devices for single-cell Analysis of biological production processes”. Presented at the Kolloquium Synthetic Biology - Opportunities for Interdisciplinary Research from Biology to Engineering, Aachen, Germany.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912565
Grünberger, A., Probst, C., Frunzke, J., Noack, S., Wiechert, W., and Kohlheyer, D. (2015).“Single-cell microfluidics meets applied biotechnology. From expectation to application”. Presented at the Conference "Cell Factories and Biosustainability - Technologies for Cell Factory Construction", Hillerod, Denmark.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912584
Probst, C., Grünberger, A., Braun, N., Helfrich, S., Nöh, K., Wiechert, W., and Kohlheyer, D. (2015). Rapid inoculation of single bacteria into parallel picoliter fermentation chambers. Analytical methods 7, 91-98.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912773
Grünberger, A., Probst, C., Frunzke, J., Noack, S., Wiechert, W., and Kohlheyer, D. (2015).“Single-cell microfluidics meets applied biotechnology. From expectation to application”. Presented at the Jahreskongress Biotechnologie 2020+, Berlin, Germany.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912545
Loeschcke, A., Thies, S., Hage-Hülsmann, J., Grünberger, A., Binder, D., Domröse, A., Klein, A., Kohlheyer, D., Pietruszka, J., Jaeger, K. - E., et al. (2015).“Heterologous production of antibacterial secondary metabolites from Serratia marcescens in Pseudomonas putida”. Presented at the 6th Congress of European Microbiologists (FEMS 2015), Maastricht, Netherlands.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912548
Bier, C., Binder, D., Grünberger, A., Drobietz, D., Hage-Hülsmann, J., Kohlheyer, D., Loeschke, A., Jaeger, K. - E., Drepper, T., and Pietruszka, J. (2015).“Caged Compounds for Biotechnological and Synthetic Biological Applications”. Presented at the European Society for Photobiology 2015 Congress, Aveiro, Portugal.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912550
Grünberger, A., Probst, C., Helfrich, S., Nanda, A., Stute, B., Wiechert, W., von Lieres, E., Nöh, K., Frunzke, J., and Kohlheyer, D. (2015). Spatiotemporal microbial single-cell analysis using a high-throughput microfluidics cultivation platform. Cytometry / A 87, 1101–1115.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912555
Helfrich, S., Azzouzi, C. E., Probst, C., Seiffarth, J., Grünberger, A., Wiechert, W., Kohlheyer, D., and Nöh, K. (2015). Vizardous: interactive analysis of microbial populations with single cell resolution. Bioinformatics 31, 3875-3877.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912557
Westerwalbesloh, C., Grünberger, A., Stute, B., Weber, S., Wiechert, W., Kohlheyer, D., and von Lieres, E. (2015). Modeling and CFD Simulation of nutrient Distribution in picoliter bioreactors for bacterial growth studies on single-cell level. Lab on a chip 15, 4177-4186.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912562
Grünberger, A. (2015). Einzelzell-Bioreaktoren - fast unsichtbar, aber nicht unscheinbar. Biospektrum 21, 353-353.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912567
Grünberger, A. (2015).“Single-cell bioreactors: Improving the understanding of microbial metabolism”. Presented at the 30. Jahrestagung der Vereinigung für Allgemeine und Angewandte Mikrobiologie, Marburg (Germany.
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2015 | Dissertation | Veröffentlicht | PUB-ID: 2912574
Grünberger, A. (2015). Single-Cell Analysis of Microbial Production Strains in Microfluidic Bioreactors. Schriften des Forschungszentrums Jülich. Reihe Schlüsseltechnologien / Key Technologies, 114, Jülich: RWTH Aachen.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912549
Mahr, R., Mustafi, N., Grünberger, A., Helfrich, S., Nöh, K., Kohlheyer, D., and Frunzke, J. (2015).“Metabolite biosensors for single cell Analysis and the Evolution of production strains”. Presented at the 30. Jahrestagung der Vereinigung für Allgemeine und Angewandte Mikrobiologie, Marburg, Germany.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912551
Probst, C., Grünberger, A., Krämer, C., Sachs, C. C., Wiechert, W., Baumgart, M., and Kohlheyer, D. (2015).“Genetically encoded sensor analysis with spatial and temporal Resolution by time-lapse imaging”. Presented at the 1st Evaluation Symposium, Molecular Interaction Engineering, MIE-Project, Karlsruhe, Germany.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912556
Binder, D., Probst, C., Bier, C., Loeschcke, A., and Grünberger, A. (2015). Lichtgesteuerte Genexpression auf Einzelzellebene. Biospektrum 21, 612-615.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912563
Sachs, C. C., Helfrich, S., Grünberger, A., Probst, C., Wiechert, W., Kohlheyer, D., and Nöh, K. (2015).“High-throughput, long-term growth characterization of C. glutamicum on single cell level using the Mother Machine”. Presented at the 3rd International Conference of the Cluster of Excellence Tailor-Made Fuels from Biomass, Aachen, Germany.
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2015 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912568
Dusny, C., Grünberger, A., Probst, C., Wiechert, W., Kohlheyer, D., and Schmid, A. (2015). Technical bias of microcultivation environments on single cell physiology. Lab on a chip 15, 1822-1834.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912804
Krämer, C., Helfrich, S., Singh, A., Grünberger, A., Wiechert, W., Nöh, K., and Kohlheyer, D. (2015).“Instantaneous microfluidic metabolic activity sensing for non-invasive single cell physiology analysis of a prokaryote and its descendants”. Presented at the 3nd International Conference IMPLEMENTATION OF MICROREACTOR TECHNOLOGY INTO BIOTECHNOLOGY (IMTB 2015), Opatija, Croatia.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912763
Grünberger, A. (2015).“Microfluidic Single-Cell Cultivation: The key for next generation bioprocess development?”. Presented at the Colloquium Biotechnology, Technical Faculty - Bielefeld University, Bielefeld.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912542
Probst, C., Grünberger, A., Binder, D., Steffen, I., Wiechert, W., and Kohlheyer, D. (2015).“Optical control of gene expression in bacteria on the single-cell level by caged compounds”. Presented at the Synthetic Biology: Opportunities for Interdisciplinary Research from Biology to Engineering, Aachen, Germany.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912559
Sachs, C. C., Helfrich, S., Grünberger, A., Probst, C., Wiechert, W., Kohlheyer, D., and Nöh, K. (2015).“High-throughput long-term growth characterization of C. glutamicum on single cell using the Mother Machine”. Presented at the Colloquium Synthetic Biology - Opportunities for Interdisciplinary Research from Biology to Engineering, Aachen, Germany.
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2015 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912566
Grünberger, A., Probst, C., Wiechert, W., and Kohlheyer, D. (2015).“Single-Cell Bioreactors: Cutting Edge Cultivation Devices for the Ultimate Scale-Down of Bioprocesses”. Presented at the DECHEMA-Himmelfahrtstagung "Scale-up and scale-down of bioprocesses", Hamburg-Bergedorf, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912589
Helfrich, S., Krämer, C., Grünberger, A., Azzouzi, C. E., Pfeifer, E., Frunzke, J., Wiechert, W., Kohlheyer, D., and Nöh, K. (2014).“Microfluids as platform for the spatiotemporal analysis of bacterial populations at single-cell level”. Presented at the 30th Symposium "Mechanisms of Gene Regulation" of the VAAM study group "Regulation & Signal Transduction in Prokaryotes", Düsseldorf, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912591
Grünberger, A., Probst, C., Frunzke, J., Noack, S., Wiechert, W., and Kohlheyer, D. (2014).“Microfluidic Single-Cell Cultivation: Opportunity for Industrial Bioprocess Development”. Presented at the EMBL Conference – Microfluidics 2014, Heidelberg, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912596
Grünberger, A., Probst, C., Unthan, S., Mustafi, N., Frunzke, J., Noack, S., Wiechert, W., and Kohlheyer, D. (2014).“Single-cell cultivation in picoliter scale: Opportunity for bioprocess development”. Presented at the 3rd BioProScale Symposium, Berlin, Germany.
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912616
Unthan, S., Grünberger, A., van Ooyen, J., Gätgens, J., Heinrich, J., Paczia, N., Wiechert, W., Kohlheyer, D., and Noack, S. (2014). Beyond growth rate 0.6. What drives Corynebacterium glutamicum to higher growth rates in defined medium. Biotechnology and bioengineering 111, 359–371.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912806
Binder, D., Grünberger, A., Loeschcke, A., Probst, C., Bier, C., Pietruszka, J., Wiechert, W., Kohlheyer, D., Jäger, K. - E., and Drepper, T. (2014).“Cage me if you can! Optogenetic bacterial gene regulation using photocaged inducers”. Presented at the 30th Symposium „Mechanisms of gene regulation”, Düsseldorf, Germany.
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912730
Nanda, A. M., Heyer, A., Kramer, C., Grünberger, A., Kohlheyer, D., and Frunzke, J. (2014). Analysis of SOS-Induced Spontaneous Prophage Induction in Corynebacterium glutamicum at the Single-Cell Level. Journal of Bacteriology 196, 180-188.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912766
Grünberger, A. (2014).“Picoliter Bioreactors. Learning from Single Cells about Large Scale Processes”. Presented at the iGEM Meetup, Aachen, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912805
Kohlheyer, D., Grünberger, A., Weber, S., Nedbal, L., and Wiechert, W. (2014).“Microfluidic Single-Cell Analysis – Potential for Microalgae Research?”. Presented at the BioSC Workshop | Exploration "Perspectives of Algal Technologies", Jülich, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912808
Mahr, R., Mustafi, N., Grünberger, A., Helfrich, S., Nöh, K., Kohlheyer, D., and Frunzke, J. (2014).“Metabolite biosensors for single cell analysis and the development of production strains”. Presented at the 30th Symposium „Mechanisms of gene regulation”, Düsseldorf, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912569
Binder, D., Grünberger, A., Loeschcke, A., Probst, C., Bier, C., Pietruszka, J., Wiechert, W., Kohlheyer, D., Jaeger, K. - E., and Drepper, T. (2014).“Cage me if you can! Optogenetic bacterial gene regulation using photocaged inducers”. Presented at the VAAM Jahrestagung, Dresden, Germany.
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2014 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912571
Grünberger, A., Probst, C., Helfrich, S., Frunzke, J., Noack, S., Nöh, K., Wiechert, W., and Kohlheyer, D. (2014). “Microfluidic Single-Cell Analysis Platform for Biotechnological Process Development” in MicroTAS 2014 (San Diego, California: CBM Society), 3 p.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912576
Dusny, C., Grünberger, A., Wiechert, W., Kohlheyer, D., and Schmid, A. (2014).“From extracellular Environment to functional phenotype. Quantitative comparison of single cell physiology in static and steady environments”. Presented at the 3rd BioProScale Symposium "Inhomogeneities in large-scale bioprocesses. System biology and process dynamics", Berlin, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912583
Grünberger, A., Probst, C., Wiechert, W., and Kohlheyer, D. (2014).“Picoliter Bioreactors. Learning from Single Cells about Large-Scale Bioprocesses”. Presented at the 24th Annual conference of the German Society for Cytometry, Dresden, Germany.
PUB
 
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912586
Helfrich, S., Azzouzi, C. E., Krämer, C., Pfeifer, E., Grünberger, A., Mustafi, N., Wiechert, W., Frunzke, J., Kohlheyer, D., and Nöh, K. (2014).“Microbial Populations on the Microfluidic Analyst's Couch: Approaching Cellular Heterogeneity”. Presented at the BioImage Informatics 2014, Leuven, Belgium.
PUB
 
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912588
Helfrich, S., Grünberger, A., Kohlheyer, D., Wiechert, W., and Nöh, K. (2014).“Investigating single-cell growth of microbial cell factories: is counting cells enough?”. Presented at the 2nd International Workshop on Image-based Systems Biology, Jena (Germany.
PUB
 
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912590
Mahr, R., Mustafi, N., Grünberger, A., Helfrich, S., Nöh, K., Kohlheyer, D., and Frunzke, J. (2014).“Transcription factor-based biosensor for microbial strain development”. Presented at the 30th Symposium "Mechanisms of Gene Regulation" of the VAAM study group "Regulation & Signal Transduction in Prokaryotes", Düsseldorf, Germany.
PUB
 
2014 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2912593
Grünberger, A., Unthan, S., Mahr, R., Frunzke, J., Noack, S., Wiechert, W., and Kohlheyer, D. (2014). Systematic screening of single-cell growth and production in a picoliter cultivation platform. Chemie Ingenieur Technik 86, 1408.
PUB | DOI
 
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912595
Kohlheyer, D., Grünberger, A., Probst, C., Helfrich, S., Frunzke, J., Eggeling, L., Nöh, K., Noack, S., and Wiechert, W. (2014).“Single-cell Bioreactors boost Bioprocess Development: New Insights into Cellular Metabolism”. Presented at the Metabolic Engineering X, Vancouver, Canada.
PUB
 
2014 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912601
Grünberger, A., Schmitz, K., Probst, C., Noack, S., Wiechert, W., and Kohlheyer, D. (2014). “Simple microfluidics for complex organisms: A microfluidic chip System for growth and Morphogenesis studies of filamentous fungi” in 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2013) (Red Hook, NY: Curran).
PUB
 
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912575
Krämer, C., Helfrich, S., Azzouzi, C. E., Grünberger, A., Pfeifer, E., Frunzke, J., Wiechert, W., Nöh, K., and Kohlheyer, D. (2014).“Microfluidics as platform for the spatiotemporal analysis of bacterial populations at single-cell level”. Presented at the International Meeting, Phenotypic heterogeneity and sociobiology of bacterial populations, Irsee, Germany.
PUB
 
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912582
Grünberger, A., Probst, C., Nanda, A., Frunzke, J., Wiechert, W., and Kohlheyer, D. (2014).“Microfluidic Single-Cell Cultivation Systems: Versatile Tools for Microbiology”. Presented at the 4th Annual Conference of the Association for General and Applied Microbiology, Dresden, Germany.
PUB
 
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912587
Mahr, R., Mustafi, N., Grünberger, A., Helfrich, S., Nöh, K., Kohlheyer, D., and Frunzke, J. (2014).“Metabolite biosensors for single cell analysis and the development of production strains”. Presented at the Gemeinsame Jahrestagung der Deutschen Gesellschaft für Hygiene und Mikrobiologie und der Vereinigung für Allgemeine und Angewandte Mikrobiologie, Dresden, Germany.
PUB
 
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912594
Binder, D., Grünberger, A., Loeschcke, A., Probst, C., Bier, C., Pietruszka, J., Wiechert, W., Kohlheyer, D., Jaeger, K. - E., and Drepper, T. (2014). Light-responsive control of bacterial gene Expression: precise triggering of the lac promoter activity using photocaged IPTG. Integrative biology 6, 755-765.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912823
Mahr, R., Mustafi, N., Grünberger, A., Helfrich, S., Nöh, K., Kohlheyer, D., and Frunzke, J. (2014).“Application of a genetically-encoded metabolite sensor for single cell analysis and development of production strains”. Presented at the Metabolic engineering X, Vancouver, Canada.
PUB
 
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912814
Grünberger, A., and Probst, C. (2014).“Introduction into Microfluidic Single-Cell Analysis”. Presented at the Biology feat, Engineering – SYNBIO – Single Cell Analysis in Microfluidic Devices (Workshop), Jülich, Germany.
PUB
 
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912605
Schendzielorz, G., Dippong, M., Grünberger, A., Kohlheyer, D., Yoshida, A., Binder, S., Nishiyama, C., Nishiyama, M., Bott, M., and Eggeling, L. (2014). Taking Control over Control: Use of Product Sensing in Single Cells to Remove Flux Control at Key Enzymes in Biosynthesis Pathways. ACS Synthetic Biology 3, 21–29.
PUB | DOI | WoS | PubMed | Europe PMC
 
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912573
Mustafi, N., Grünberger, A., Mahr, R., Helfrich, S., Nöh, K., Blombach, B., Kohlheyer, D., and Frunzke, J. (2014). Application of a Genetically Encoded Biosensor for Live Cell Imaging of L-Valine Production in Pyruvate Dehydrogenase Complex-Deficient Corynebacterium glutamicum Strains. PLoS one 9:e85731.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912580
Dusny, C., Grünberger, A., Rosenthal, K., Wiechert, W., and Schmid, A. (2014).“Quantitative Physiology of Single Cells for Linking Phenotype and Environment”. Presented at the 24th Annual Conference of the German Society for Flow Cytometry, Dresden, Germany.
PUB
 
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912585
Sachs, C. C., Grünberger, A., Wiechert, W., Nöh, K., and Kohlheyer, D. (2014).“Robust Automated Image Analysis of Mother Machine Microfluidic Growth Devices”. Presented at the BioImage Informatics 2014, Leuven, Belgium.
PUB
 
2014 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2912592
Weber, S., Grünberger, A., Probst, C., Wiechert, W., and Kohlheyer, D. (2014). Optimizing growth performance of Corynebacterium glutamicum at the single-cell level. Chemie Ingenieur Technik 88, 1414.
PUB | DOI
 
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912597
Grünberger, A., Wiechert, W., and Kohlheyer, D. (2014). Single-cell microfluidics: opportunity for bioprocess development. Current opinion in biotechnology 29, 15-23.
PUB | DOI | WoS | PubMed | Europe PMC
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912604
Mahr, R., Mustafi, N., Grünberger, A., Helfrich, S., Nöh, K., Kohlheyer, D., and Frunzke, J. (2013).“Application of a genetically encoded biosensor for single cell analysis and strain development of production strains”. Presented at the New concepts and approaches in microbiology, Heidelberg, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912609
Nanda, A., Heyer, A., Grünberger, A., Helfrich, S., Kohlheyer, D., Nöh, K., and Frunzke, J. (2013).“Single-cell Dynamics of the SOS Response in Corynebacterium glutamicum”. Presented at the Bacterial Networks, Pultusk, Poland.
PUB
 
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912611
Probst, C., Grünberger, A., Wiechert, W., and Kohlheyer, D. (2013). Polydimethylsiloxane (PDMS) Sub-Micron Traps for Single-Cell Analysis of Bacteria. Micromachines 4, 357-369.
PUB | PDF | DOI | WoS
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912623
Heyer, A., Nanda, A., Grünberger, A., Kohlheyer, D., and Frunzke, J. (2013).“Spontaneous prophage induction in Corynebacterium glutamicum”. Presented at the VAAM-Tagung 2013, Bremen, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912630
Kohlheyer, D., Grünberger, A., Probst, C., Krämer, C., Eggeling, L., Frunzke, J., and Wiechert, W. (2013).“Microbial single cell analysis of production strains in microfabricated habitats”. Presented at the DECHEMA-Workshop Microfluidics for Systems Biology and Bioprocess Development, Frankfurt, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912825
Binder, D., Grünberger, A., Loeschcke, A., Probst, C., Pietruszka, J., Wiechert, W., Kohlheyer, D., Jaeger, K. E., and Drepper, T. (2013).“Characterization of light-triggered gene expression in E. coli with respect to population and single cell response”. Presented at the Jülich Biotech Day, Jülich, Germany.
PUB
 
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912745
Grünberger, A., Lai, P. - K., Blanco, M. A., and Roberts, C. J. (2013). Coarse-Grained Modeling of Protein Second Osmotic Virial Coefficients: Sterics and Short-Ranged Attractions. The Journal of Physical Chemistry B 117, 763-770.
PUB | DOI | WoS | PubMed | Europe PMC
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912810
Helfrich, S., Grünberger, A., Kohlheyer, D., Wiechert, W., and Nöh, K. (2013).“Analysis of microbial observables on single cell level: Challenges of Cell Clusters for Microscopy-based Image Processing”. Presented at the 9th European Congress of Chemical Engineering (ECCE9)/ 2nd European Congress of Applied Biotechnology (ECAB2), The Hague, Netherlands.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912824
Nanda, A. M., Heyer, A., Grünberger, A., Helfrich, S., Kohlheyer, D., Nöh, K., and Frunzke, J. (2013).“Single-cell dynamics of the SOS response in Corynebacterium glutamicum”. Presented at the Jülich Biotech Day, Jülich, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912827
Mahr, R., Mustafi, N., Grünberger, A., Helfrich, S., Nöh, K., Kohlheyer, D., and Frunzke, J. (2013).“Application of a genetically- encoded metabolite sensor for single cell analysis and the development of production strains”. Presented at the Jülich Biotech Day, Jülich, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912829
Sachs, C., Grünberger, A., Probst, C., Wiechert, W., and Kohlheyer, D. (2013).“Automated image analysis pipeline for single cell bacterial growth studies”. Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912834
Binder, D., Grünberger, A., Loeschcke, A., Probst, C., Pietruszka, J., Wiechert, W., Kohlheyer, D., Jaeger, K. E., and Drepper, T. (2013).“Characterization of light-triggered gene expression in E. coli with respect to population and single cell response”. Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912836
Binder, D., Grünberger, A., Loeschcke, A., Probst, C., Pietruszka, J., Wiechert, W., Kohlheyer, D., Jaeger, K. E., and Drepper, T. (2013).“Characterization of light-triggered gene expression in E. coli with respect to population and single cell response”. Presented at the New Approaches and Concepts in Microbiology, Heidelberg, Germany.
PUB
 

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