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199 Publikationen

2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912806
Binder D, Grünberger A, Loeschcke A, Probst C, Bier C, Pietruszka J, Wiechert W, Kohlheyer D, Jäger K-E, Drepper T (2014)
Cage me if you can! Optogenetic bacterial gene regulation using photocaged inducers.
Presented at the 30th Symposium „Mechanisms of gene regulation”, Düsseldorf, Germany.
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912730
Nanda AM, Heyer A, Kramer C, Grünberger A, Kohlheyer D, Frunzke J (2014)
Analysis of SOS-Induced Spontaneous Prophage Induction in Corynebacterium glutamicum at the Single-Cell Level.
Journal of Bacteriology 196(1): 180-188.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912766
Grünberger A (2014)
Picoliter Bioreactors. Learning from Single Cells about Large Scale Processes.
Presented at the iGEM Meetup, Aachen, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912805
Kohlheyer D, Grünberger A, Weber S, Nedbal L, Wiechert W (2014)
Microfluidic Single-Cell Analysis – Potential for Microalgae Research?
Presented at the BioSC Workshop | Exploration "Perspectives of Algal Technologies", Jülich, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912808
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2014)
Metabolite biosensors for single cell analysis and the development of production strains.
Presented at the 30th Symposium „Mechanisms of gene regulation”, Düsseldorf, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912569
Binder D, Grünberger A, Loeschcke A, Probst C, Bier C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger K-E, Drepper T (2014)
Cage me if you can! Optogenetic bacterial gene regulation using photocaged inducers.
Presented at the VAAM Jahrestagung, Dresden, Germany.
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2014 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912571
Grünberger A, Probst C, Helfrich S, Frunzke J, Noack S, Nöh K, Wiechert W, Kohlheyer D (2014)
Microfluidic Single-Cell Analysis Platform for Biotechnological Process Development.
In: MicroTAS 2014. San Diego, California: CBM Society: 3 p.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912576
Dusny C, Grünberger A, Wiechert W, Kohlheyer D, Schmid A (2014)
From extracellular Environment to functional phenotype. Quantitative comparison of single cell physiology in static and steady environments.
Presented at the 3rd BioProScale Symposium "Inhomogeneities in large-scale bioprocesses. System biology and process dynamics", Berlin, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912583
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2014)
Picoliter Bioreactors. Learning from Single Cells about Large-Scale Bioprocesses.
Presented at the 24th Annual conference of the German Society for Cytometry, Dresden, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912586
Helfrich S, Azzouzi CE, Krämer C, Pfeifer E, Grünberger A, Mustafi N, Wiechert W, Frunzke J, Kohlheyer D, Nöh K (2014)
Microbial Populations on the Microfluidic Analyst's Couch: Approaching Cellular Heterogeneity.
Presented at the BioImage Informatics 2014, Leuven, Belgium.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912588
Helfrich S, Grünberger A, Kohlheyer D, Wiechert W, Nöh K (2014)
Investigating single-cell growth of microbial cell factories: is counting cells enough?
Presented at the 2nd International Workshop on Image-based Systems Biology, Jena (Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912590
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2014)
Transcription factor-based biosensor for microbial strain development.
Presented at the 30th Symposium "Mechanisms of Gene Regulation" of the VAAM study group "Regulation & Signal Transduction in Prokaryotes", Düsseldorf, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2912593
Grünberger A, Unthan S, Mahr R, Frunzke J, Noack S, Wiechert W, Kohlheyer D (2014)
Systematic screening of single-cell growth and production in a picoliter cultivation platform.
Chemie Ingenieur Technik 86(9): 1408.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912595
Kohlheyer D, Grünberger A, Probst C, Helfrich S, Frunzke J, Eggeling L, Nöh K, Noack S, Wiechert W (2014)
Single-cell Bioreactors boost Bioprocess Development: New Insights into Cellular Metabolism.
Presented at the Metabolic Engineering X, Vancouver, Canada.
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2014 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912601
Grünberger A, Schmitz K, Probst C, Noack S, Wiechert W, Kohlheyer D (2014)
Simple microfluidics for complex organisms: A microfluidic chip System for growth and Morphogenesis studies of filamentous fungi.
In: 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2013). Red Hook, NY: Curran.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912575
Krämer C, Helfrich S, Azzouzi CE, Grünberger A, Pfeifer E, Frunzke J, Wiechert W, Nöh K, Kohlheyer D (2014)
Microfluidics as platform for the spatiotemporal analysis of bacterial populations at single-cell level.
Presented at the International Meeting, Phenotypic heterogeneity and sociobiology of bacterial populations, Irsee, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912582
Grünberger A, Probst C, Nanda A, Frunzke J, Wiechert W, Kohlheyer D (2014)
Microfluidic Single-Cell Cultivation Systems: Versatile Tools for Microbiology.
Presented at the 4th Annual Conference of the Association for General and Applied Microbiology, Dresden, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912587
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2014)
Metabolite biosensors for single cell analysis and the development of production strains.
Presented at the Gemeinsame Jahrestagung der Deutschen Gesellschaft für Hygiene und Mikrobiologie und der Vereinigung für Allgemeine und Angewandte Mikrobiologie, Dresden, Germany.
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912594
Binder D, Grünberger A, Loeschcke A, Probst C, Bier C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger K-E, Drepper T (2014)
Light-responsive control of bacterial gene Expression: precise triggering of the lac promoter activity using photocaged IPTG.
Integrative biology 6(8): 755-765.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912823
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2014)
Application of a genetically-encoded metabolite sensor for single cell analysis and development of production strains.
Presented at the Metabolic engineering X, Vancouver, Canada.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912814
Grünberger A, Probst C (2014)
Introduction into Microfluidic Single-Cell Analysis.
Presented at the Biology feat, Engineering – SYNBIO – Single Cell Analysis in Microfluidic Devices (Workshop), Jülich, Germany.
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912605
Schendzielorz G, Dippong M, Grünberger A, Kohlheyer D, Yoshida A, Binder S, Nishiyama C, Nishiyama M, Bott M, Eggeling L (2014)
Taking Control over Control: Use of Product Sensing in Single Cells to Remove Flux Control at Key Enzymes in Biosynthesis Pathways.
ACS Synthetic Biology 3(1): 21–29.
PUB | DOI | WoS | PubMed | Europe PMC
 
2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912573
Mustafi N, Grünberger A, Mahr R, Helfrich S, Nöh K, Blombach B, Kohlheyer D, Frunzke J (2014)
Application of a Genetically Encoded Biosensor for Live Cell Imaging of L-Valine Production in Pyruvate Dehydrogenase Complex-Deficient Corynebacterium glutamicum Strains.
PLoS one 9(1): e85731.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912580
Dusny C, Grünberger A, Rosenthal K, Wiechert W, Schmid A (2014)
Quantitative Physiology of Single Cells for Linking Phenotype and Environment.
Presented at the 24th Annual Conference of the German Society for Flow Cytometry, Dresden, Germany.
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2014 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912585
Sachs CC, Grünberger A, Wiechert W, Nöh K, Kohlheyer D (2014)
Robust Automated Image Analysis of Mother Machine Microfluidic Growth Devices.
Presented at the BioImage Informatics 2014, Leuven, Belgium.
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2014 | Kurzbeitrag Konferenz / Poster | Veröffentlicht | PUB-ID: 2912592
Weber S, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2014)
Optimizing growth performance of Corynebacterium glutamicum at the single-cell level.
Chemie Ingenieur Technik 88(9): 1414.
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2014 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912597
Grünberger A, Wiechert W, Kohlheyer D (2014)
Single-cell microfluidics: opportunity for bioprocess development.
Current opinion in biotechnology 29: 15-23.
PUB | DOI | WoS | PubMed | Europe PMC
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912604
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2013)
Application of a genetically encoded biosensor for single cell analysis and strain development of production strains.
Presented at the New concepts and approaches in microbiology, Heidelberg, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912609
Nanda A, Heyer A, Grünberger A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2013)
Single-cell Dynamics of the SOS Response in Corynebacterium glutamicum.
Presented at the Bacterial Networks, Pultusk, Poland.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912611
Probst C, Grünberger A, Wiechert W, Kohlheyer D (2013)
Polydimethylsiloxane (PDMS) Sub-Micron Traps for Single-Cell Analysis of Bacteria.
Micromachines 4(4): 357-369.
PUB | PDF | DOI | WoS
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912623
Heyer A, Nanda A, Grünberger A, Kohlheyer D, Frunzke J (2013)
Spontaneous prophage induction in Corynebacterium glutamicum.
Presented at the VAAM-Tagung 2013, Bremen, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912630
Kohlheyer D, Grünberger A, Probst C, Krämer C, Eggeling L, Frunzke J, Wiechert W (2013)
Microbial single cell analysis of production strains in microfabricated habitats.
Presented at the DECHEMA-Workshop Microfluidics for Systems Biology and Bioprocess Development, Frankfurt, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912825
Binder D, Grünberger A, Loeschcke A, Probst C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger KE, Drepper T (2013)
Characterization of light-triggered gene expression in E. coli with respect to population and single cell response.
Presented at the Jülich Biotech Day, Jülich, Germany.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912745
Grünberger A, Lai P-K, Blanco MA, Roberts CJ (2013)
Coarse-Grained Modeling of Protein Second Osmotic Virial Coefficients: Sterics and Short-Ranged Attractions.
The Journal of Physical Chemistry B 117(3): 763-770.
PUB | DOI | WoS | PubMed | Europe PMC
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912810
Helfrich S, Grünberger A, Kohlheyer D, Wiechert W, Nöh K (2013)
Analysis of microbial observables on single cell level: Challenges of Cell Clusters for Microscopy-based Image Processing.
Presented at the 9th European Congress of Chemical Engineering (ECCE9)/ 2nd European Congress of Applied Biotechnology (ECAB2), The Hague, Netherlands.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912824
Nanda AM, Heyer A, Grünberger A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2013)
Single-cell dynamics of the SOS response in Corynebacterium glutamicum.
Presented at the Jülich Biotech Day, Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912827
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2013)
Application of a genetically- encoded metabolite sensor for single cell analysis and the development of production strains.
Presented at the Jülich Biotech Day, Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912829
Sachs C, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Automated image analysis pipeline for single cell bacterial growth studies.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912834
Binder D, Grünberger A, Loeschcke A, Probst C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger KE, Drepper T (2013)
Characterization of light-triggered gene expression in E. coli with respect to population and single cell response.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912836
Binder D, Grünberger A, Loeschcke A, Probst C, Pietruszka J, Wiechert W, Kohlheyer D, Jaeger KE, Drepper T (2013)
Characterization of light-triggered gene expression in E. coli with respect to population and single cell response.
Presented at the New Approaches and Concepts in Microbiology, Heidelberg, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912603
Grünberger A, Probst C, Unthan S, Krämer C, Paczia N, Noack S, Wiechert W, Kohlheyer D (2013)
Single Cell Bioreactors for Bioprocess Optimization.
Presented at the Jülich Biotech Day 2013, Jülich,Germany.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912606
Hoffmann K, Grünberger A, Lausberg F, Bott M, Eggeling L (2013)
Visualization of Imbalances in Sulfur Assimilation and Synthesis of Sulfur-Containing Amino Acids at the Single-Cell Level.
Applied and environmental microbiology 79(21): 6730-6736.
PUB | DOI | WoS | PubMed | Europe PMC
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912608
Nanda A, Heyer A, Krämer C, Grünberger A, Kohlheyer D, Frunzke J (2013)
SOS-induced spontaneous prophage induction in Corynebacterium glutamicum.
Presented at the Jülich Biotech Day 2013, Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912613
Probst C, Grünberger A, Frunzke J, Wiechert W, Kohlheyer D (2013)
Microfluidic cultivation technology and application: analysing single-microbes under perfect environmental control.
Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912615
Helfrich S, Azzouzi CE, Grünberger A, Wiechert W, Nöh K (2013)
Explorative Analysis of Cell Population Development: Customizable Interactive Lineage Trees.
Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912618
Kohlheyer D, Grünberger A, Probst C, Frunzke J, Wiechert W (2013)
Picoliter fermentation with single bacteria: Learning from the one to unravel the crowd.
Presented at the 2nd International Congress Implementation of Microreactor Technology in Biotechnology, Cavtat, Croatia.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912620
Noack S, Grünberger A, van Ooyen J, Kohlheyer D, Wiechert W (2013)
Increasing biomass productivity of C. glutamicum - new insights from microscale cultivations.
Presented at the 9th European Congress of Chemical Engineering, Den Haag, The Netherlands.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912622
Wiechert W, Kohlheyer D, Noack S, Frunzke J, Mustafi N, Grünberger A (2013)
Picoliter Bioreactors. Learning from Single Cells about Large Scale Processes.
Presented at the Copenhagen Bioscience Conferences, Cell Factories and Biosustainability, Favrholm, Denmark.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912625
Heinrich J, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Single cell growth under constant environmental conditions and defined C sources: A case study for Corynebacterium glutamicum.
Presented at the VAAM-Tagung 2013, Bremen, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912627
Probst C, Frank P, Grünberger A, Wiechert W, Kohlheyer D (2013)
Time lapse microbial single cell analysis in a micro fabricated batch reactor.
Presented at the Single Cell Analysis Europe 2013, Barcelona, Spain.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2614036
Baumgart M, Unthan S, Rückert C, Sivalingam J, Grünberger A, Kalinowski J, Bott M, Noack S, Frunzke J (2013)
Construction of a prophage-free variant of Corynebacterium glutamicum ATCC 13032 - a platform strain for basic research and industrial biotechnology.
Applied and environmental microbiology 79(19): 6006-6015.
PUB | DOI | WoS | PubMed | Europe PMC
 
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912599
Grünberger A, Probst C, Heyer A, Wiechert W, Frunzke J, Kohlheyer D (2013)
Microfluidic Picoliter Bioreactor for Microbial Single-cell Analysis: Fabrication, System Setup, and Operation.
Journal of visualized experiments. Bioengineering 82: UNSP e50560.
PUB | PDF | DOI | WoS
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912602
Grünberger A, Helfrich S, Mustafi N, Probst C, Frunzke J, Nöh K, Wiechert W, Kohlheyer D (2013)
Automated High-Throughput Time-Lapse Microscopy of Bacteria Microcolonies in Parallelized Monolayer Growth Chambers.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications, Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912607
Nanda A, Heyer A, Krämer C, Grünberger A, Kohlheyer D, Frunzke J (2013)
SOS-induced spontaneous prophage induction in Corynebacterium glutamicum.
Presented at the Nikon Symposium on Advanced Imaging in Cell- and Microbiology Technology and Applications, Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912614
Krämer C, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Continuous Non-Invasive Real-Time Viability Measurement of Bacteria on Single Cell Level in Microfluidic Chip Cultures.
Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912619
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Femtoliter chemostat for long-term bacteria growth and production analysis on single cell level.
Presented at the 2nd International Conference Implementation of Microreactor Technology in Biotechnology, Cavtat, Croatia.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912621
Grünberger A, Mustafi N, Probst C, Frunzke J, Wiechert W, Kohlheyer D (2013)
Towards High-Throughput Microbial Single Cell Analysis In Picoliter Bioreactors.
Presented at the 9th European Congress of Chemical Engineering, Den Haag, The Netherlands.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912626
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Femtoliter chemostat for long-term bacteria growth and production analysis on single cell level.
Presented at the Single Cell Analysis Europe 2013, Barcelona, Spain.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912809
Frunzke J, Mahr R, Grünberger A, Mustafi N, Kohlheyer D (2013)
Microbial Metabolite Production – Live in Concert.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912828
Krämer C, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Continuous Non-Invasive Real-Time Viability Measurement of Bacteria on Single Cell Level in Microfluidic Chip Cultures?
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912830
Probst C, Grünberger A, Krämer C, Wiechert W, Kohlheyer D (2013)
Microfluidic single-cell analysis in dynamic environments.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912835
Mahr R, Mustafi N, Grünberger A, Helfrich S, Nöh K, Kohlheyer D, Frunzke J (2013)
Application of a genetically- encoded metabolite sensor for single cell analysis and the development of production strains.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912826
Helfrich S, Azzouzi CE, Grünberger A, Wiechert W, Nöh K (2013)
Exploration and Analysis of cell population development. Customizable interactive lineage trees.
Presented at the Jülich Biotech Day, Jülich, Germany.
PUB
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912833
Nanda AM, Heyer A, Grünberger A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2013)
Single-cell dynamics of the SOS response in Corynebacterium glutamicum.
Presented at the Advanced Imaging in Cell- and Microbiology: Technology and Applications (AICMB), Jülich, Germany.
PUB
 
2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912600
Probst C, Grünberger A, Wiechert W, Kohlheyer D (2013)
Microfluidic growth chambers with optical tweezers for full spatial single-cell control and analysis of evolving microbes.
Journal of microbiological methods 95(3): 470-476.
PUB | DOI | WoS | PubMed | Europe PMC
 
2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912612
Nanda A, Heyer A, Krämer C, Grünberger A, Kohlheyer D, Frunzke J (2013)
SOS-induced spontaneous prophage induction in Corynebacterium glutamicum.
Presented at the EMBL Heidelberg "New Approaches and Concepts in Microbiology", Heidelberg, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912617
Krämer C, Grünberger A, Probst C, Wiechert W, Kohlheyer D (2013)
Continuous viability fluorescent staining of growing Corynebacterium glutamicum colonies without sample preparation in an automated microfluidic measurement system.
Presented at the How Deas Is Dead III Conference, Berlin, Germany.
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2013 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912624
Grünberger A, Mustafi N, Probst C, Frunzke J, Wiechert W, Kohlheyer D (2013)
High-throughput Microbial Single Cell analysis in Picoliter Bioreactors.
Presented at the VAAM-Tagung 2013, Bremen, Germany.
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2013 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912631
Grünberger A, van Ooyen J, Paczia N, Rohe P, Schendzielorz G, Eggeling L, Wiechert W, Kohlheyer D, Noack S (2013)
Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments.
Biotechnology and bioengineering 110(1): 220-228.
PUB | DOI | WoS | PubMed | Europe PMC
 
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912635
Binder S, Schendzielorz G, Kohlheyer D, Grünberger A, Wiechert W, Bott M, Eggeling L (2012)
Metabolite sensors for single-cell isolation of producing bacteria.
Presented at the Metabolic Engineering IX, Biarritz, France.
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912642
Grünberger A, Frank P, Probst C, Wiechert W, Kohlheyer D (2012)
Single Cell Microfluidics: From Fabrication to Application.
Presented at the Jülich Biotech Day, Jülich, Germany.
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912647
Helfrich S, Grünberger A, Kohlheyer D, Wiechert W, Nöh K (2012)
Semi-Automated Evaluation of Microbial Observables from High-Throughput Time-lapse Microscopy.
Presented at the German Conference on Bioinformatics 2012, Jena (Germany).
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912767
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2012)
Fermentation at Picoliter Scale: Microfluidics for single cell analysis of prokaryotic production strains.
Presented at the Achema 2012, Frankfurt, Germany.
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2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912837
Probst C, Grünberger A, Wiechert W, Kohlheyer D (2012)
Screening of Escherichia coli on single-cell level by hyphenating microfluidic picoliter fermentation and optical tweezers.
Presented at the 3rd European Conference on Microfluidics, Heidelberg, Germany.
PUB
 
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912728
Grünberger A, Paczia N, Probst C, Schendzielorz G, Eggeling L, Noack S, Wiechert W, Kohlheyer D (2012)
A disposable picolitre bioreactor for cultivation and investigation of industrially relevant bacteria on the single cell level.
Lab on a Chip 12(11): 2060-2068.
PUB | PDF | DOI | WoS | PubMed | Europe PMC
 
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912747
Scholz KE, Okrob D, Kopka B, Grünberger A, Pohl M, Jaeger K-E, Krauss U (2012)
Synthesis of Chiral Cyanohydrins by Recombinant Escherichia coli Cells in a Micro-Aqueous Reaction System.
Applied and Environmental Microbiology 78(14): 5025-5027.
PUB | DOI | WoS | PubMed | Europe PMC
 
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912776
Grünberger A, Probst. C, Frank P, Wiechert W, Kohlheyer D (2012)
Single Cell Analysis of Industrially Relevant Bacterial Strains in Picoliter Environments.
Presented at the EMBL Conference – Microfluidics 2012, Heidelberg, Germany.
PUB
 
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912839
Probst C, Grünberger A, Wiechert W, Kohlheyer D (2012)
Phenotypic Sorting and Analysis of Bacteria Production Strains using Optical Tweezers and Microfluidics.
Presented at the EMBL Conference – Microfluidics 2012, Heidelberg, Germany.
PUB
 
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912841
Nanda AM, Grünberger A, Heyer A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2012)
Dynamics of the SOS response in single cells of Corynebacterium glutamicum.
Presented at the 2nd Molecular Microbiology Meeting Würzburg, Würzburg, Germany.
PUB
 
2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912639
Probst C, Grünberger A, Kohlheyer D, Wiechert W (2012)
Phenotypic Sorting and Analysis of Bacteria ProductionStrains Using Optical Tweezers and Microfluidics.
Chemie - Ingenieur - Technik: CIT 84(8): 1344.
PUB | DOI
 
2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912641
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2012)
Femtoliter Growth Channels. Bacteria Long-Term Growth Patterns Analysis on Singel Cell Level.
Chemie - Ingenieur - Technik (CIT) 84(8): 1407.
PUB | DOI
 
2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912646
Grünberger A, Helfrich S, Probst C, Nöh K, Wiechert W, Kohlheyer D (2012)
Industrial Biotechnology meets Microfluidics - Disposable high-throughput single cell analysis device for industrially relevant bacterial strains.
In: Proceedings - µFLU-12. Colin S (Ed); Publications S.H.F., Paris: SHF.
PUB
 
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912633
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2012)
Picoliter bioreactors for growth heterogeneity studies of industrially relevant bacteria on single cell level.
Presented at the 2nd BioProScale Symposium: Inhomogeneities in large-scale bioprocesses: System biology and process dynamics, Berlin, Germany.
PUB
 
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912638
Mustafi N, Grünberger A, Helfrich S, Kohlheyer D, Nöh K, Bott M, Frunzke J (2012)
A biosensor for the intracellular detection of L-methionine and branched-chain amino acids - Monitoring of amino acid production at the single cell level.
Presented at the 15th International Conference on Biotechnology, Istanbul, Turkey.
PUB
 
2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912640
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2012)
High-Throughput Growth Rate Determination of Bacteria Micro colonies on Single Cell Level.
Chemie - Ingenieur - Technik: CIT 84(8): 1336-1337.
PUB | DOI
 
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912645
Kohlheyer D, Grünberger A, Probst C, Frank P, Wiechert W (2012)
Catch it and batch it: picoliter fermentation at the single cell level.
Presented at the International Workshop on New and Synthetic Bioproduction Systems, Hamburg-Harburg, Germany.
PUB
 
2012 | Zeitschriftenaufsatz | Veröffentlicht | PUB-ID: 2912746
Mustafi N, Grünberger A, Kohlheyer D, Bott M, Frunzke J (2012)
The development and application of a single-cell biosensor for the detection of l-methionine and branched-chain amino acids.
Metabolic Engineering 14(4): 449-457.
PUB | DOI | WoS | PubMed | Europe PMC
 
2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912758
Grünberger A, Probst C, Binder S, Ziaee R, Eggeling L, Wiechert W, Kohlheyer D (2012)
Single Cell Trapping and Analysis for Prokaryotic Production Strains in Sub-µm Fluidic Structures.
In: 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011 (MiroTAS 2011). Landers J (Ed); Red Hook, NY: Curran.
PUB
 
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912777
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2012)
Towards high-throughput single cell growth optimization and production analysis using picoliter bioreactors.
Presented at the Metabolic Engineering IX 2012, Biarritz, France.
PUB
 
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912838
Frank P, Probst C, Grünberger A, Wiechert W, Kohlheyer D (2012)
“Catch it and Batch it”- Microfluidics single cell batch cultivation utilizing picoliter bioreactors.
Presented at the ProcessNet- Jahrestagung 2012 und 30. DECHEMA Jahrestagung der Biotechnologen, Karlsruhe, Germany.
PUB
 
2012 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912840
Nanda AM, Grünberger A, Heyer A, Helfrich S, Kohlheyer D, Nöh K, Frunzke J (2012)
Dynamics of the SOS response in single cells of Corynebacterium glutamicum.
Presented at the Microbial Stress: from Molecules to System, Belgirate (VB)/Maggiore Lake, Italy.
PUB
 
2012 | Konferenzbeitrag | Veröffentlicht | PUB-ID: 2912643
Grünberger A, Helfrich S, Probst C, Wiechert W, Nöh K, Kohlheyer D (2012)
High-Throughput lineage tree investigations of bacteria microcolonies using arrays of monolayer growth chambers.
In: Proceedings of The Sixteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2012). San Diego, California: CBMS.
PUB
 
2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912778
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2011)
Single Cell Trapping and Analysis for Prokaryotic Production Strains in Sub -µm Fluidic Structures.
Presented at the NanoBioTech-Montreux 2011, Montreux, Switzerland.
PUB
 
2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912843
Scholz KE, Okrob D, Kopka B, Grünberger A, Pohl M, Jaeger KE, Krauss U (2011)
Fluorescence reporters for the analysis of whole cell biocatalysts in non-conventional media.
Presented at the Biotrans 2011, Giardini Naxos (Messina), Italy.
PUB
 
2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912811
Kohlheyer D, Grünberger A, Probst C, Wiechert W (2011)
Sub-µm Fluidic Structures for Single Cell Trapping and Analysis of Prokaryotic Production Strains.
Presented at the 21st Annual conference of the German Society for Cytometry, Bonn, Germany.
PUB
 
2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912842
Mustafi N, Grünberger A, Kohlheyer D, Bott M, Frunzke J (2011)
A biosensor for the intracellular detection of L-methionine and branched-chain amino acids.
Presented at the 5th International Conference on Analysis of Microbial Cells at the Single Cell Level, Caryy-Le-Rouet, France.
PUB
 
2011 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912768
Grünberger A, Probst C, Wiechert W, Kohlheyer D (2011)
A continuous picoliter bioreactor for heterogeneity studies of bacteria microcolonies.
Presented at the NanoBioTech-Montreux 2011, Montreux, Switzerland.
PUB
 
2010 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912812
Blanko MA, Grünberger A, Sahin E, Roberts CJ (2010)
Protein Interactions from Kirwood-Buff Analysis of Light Scattering and Coarse-Grained Molecular Models.
Presented at the AIChE Annual Meeting, Salt Lake City (UT), USA.
PUB
 
2009 | Kurzbeitrag Konferenz / Poster | PUB-ID: 2912813
Grünberger A, Stephens E, Hankamer B (2009)
Media optimization for the microalgae Chamydomonas reinhardtii Stm6 using statistical design.
Presented at the IMB Summer Symposium: A systems Biology approach to biofuel production: From light capture to biodiesel production, Brisbane, Australia.
PUB
 

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