PUB - Publikationen an der Universität Bielefeld

Right ventricular (RV) strain offers crucial diagnostic insights in cardiovascular and pulmonary disorders. Nonetheless, the absence of established reference values impedes its clinical implementation. Utilizing CMR-feature tracking, age- and gender-dependent RV strains were systematically assessed in 175 heart-healthy Caucasians, 97 females, median 32.5years. RV global longitudinal strain (GLS) was greater in females than males (median -26.8% (-28.3;-24.1) vs. -24.4±3.0%; p<0.001), whereby radial and circumferential strain remained comparable. Age subgroups exhibited increased RV-GLS for group B (30-50years) (-26.0±3.1% vs. -24.4±3.2%; p=0.011) and group C (>50years) (-26.7±2.3% vs. -24.4±3.2%; p<0.001) compared to group A (<30years). High intra-class correlation coefficients (ICC) were exhibited by intrarater variability (ICC=0.86-0.95) and moderate levels for interrater variability (ICC=0.50-0.73). CMR-feature tracking provides a fair quantification method of age- and gender-specific normal RV strain values, demonstrating that higher RV-GLS is linked to female gender and advancing age within a healthy Caucasian cohort. © 2024. The Author(s).