MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss

Kim R, Mihailovic D, Riemann CJ, Kilgué A, Pfeiffer C, Gehl H-B, Scholtz L-U, Todt I (2024)
Brain Sciences 14(7): 681.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
Download
OA 2.49 MB
Abstract / Bemerkung
Objectives: To study the correlation between positive cochlin tomoprotein testing (CTP), magnetic resonance (MR) imaging, and the auditory and vestibular function amongst patients with sudden hearing loss. Study Design: Prospective case series. Methods: We prospectively examined eight patients who presented with sudden hearing loss (>60 dB) with or without vertigo or tinnitus. We performed an ELISA-based CTP detection test using middle ear lavage samples. In addition to the CTP examination, a magnetic resonance imaging (MRI) examination was performed using different sequences (T1 and a T1 sequence with a contrast medium (CM), a T2 sequence, 4 h delayed intravenous gadolinium-enhanced three-dimensional fluid-attenuated inversion recovery (3D FLAIR)). Results: All patients with sudden hearing loss (>60 dB) presented a non-specific contrast enhancement in the cochlea and vestibulum on the affected side on delayed 3D-FLAIR MRI. Four patients had a positive CTP test, suggesting a perilymphatic fistula (PLF). However, no specific MRI signal for a PLF was observed. Conclusions: Using multimodal diagnostic measures, such as CTP testing and different MRI sequences, no correlation could be found in patients with a PLF.
Stichworte
magnetic resonance imaging; 4 h delayed intravenous gadolinium-enhanced; 3D FLAIR MRI; cochlin tomoprotein; sudden hearing loss; perilymphatic; fistula
Erscheinungsjahr
2024
Zeitschriftentitel
Brain Sciences
Band
14
Ausgabe
7
Art.-Nr.
681
eISSN
2076-3425
Finanzierungs-Informationen
Open-Access-Publikationskosten wurden durch die Universität Bielefeld gefördert.
Page URI
https://pub.uni-bielefeld.de/record/2991674

Zitieren

Kim R, Mihailovic D, Riemann CJ, et al. MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss. Brain Sciences . 2024;14(7): 681.
Kim, R., Mihailovic, D., Riemann, C. J., Kilgué, A., Pfeiffer, C., Gehl, H. - B., Scholtz, L. - U., et al. (2024). MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss. Brain Sciences , 14(7), 681. https://doi.org/10.3390/brainsci14070681
Kim, Rayoung, Mihailovic, Denis, Riemann, Conrad Josef, Kilgué, Alexander, Pfeiffer, Christoph, Gehl, Hans-Björn, Scholtz, Lars-Uwe, and Todt, Ingo. 2024. “MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss”. Brain Sciences 14 (7): 681.
Kim, R., Mihailovic, D., Riemann, C. J., Kilgué, A., Pfeiffer, C., Gehl, H. - B., Scholtz, L. - U., and Todt, I. (2024). MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss. Brain Sciences 14:681.
Kim, R., et al., 2024. MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss. Brain Sciences , 14(7): 681.
R. Kim, et al., “MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss”, Brain Sciences , vol. 14, 2024, : 681.
Kim, R., Mihailovic, D., Riemann, C.J., Kilgué, A., Pfeiffer, C., Gehl, H.-B., Scholtz, L.-U., Todt, I.: MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss. Brain Sciences . 14, : 681 (2024).
Kim, Rayoung, Mihailovic, Denis, Riemann, Conrad Josef, Kilgué, Alexander, Pfeiffer, Christoph, Gehl, Hans-Björn, Scholtz, Lars-Uwe, and Todt, Ingo. “MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss”. Brain Sciences 14.7 (2024): 681.
Alle Dateien verfügbar unter der/den folgenden Lizenz(en):
Creative Commons Namensnennung 4.0 International Public License (CC-BY 4.0):
Volltext(e)
Access Level
OA Open Access
Zuletzt Hochgeladen
2024-08-05T08:32:38Z
MD5 Prüfsumme
09bb97abf99ea0a794623dc73a2989c0


Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

References

Daten bereitgestellt von Europe PubMed Central.

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®
Quellen

PMID: 39061421
PubMed | Europe PMC

Suchen in

Google Scholar