MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss
Kim R, Mihailovic D, Riemann CJ, Kilgué A, Pfeiffer C, Gehl H-B, Scholtz L-U, Todt I (2024)
Brain Sciences 14(7): 681.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
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brainsci-14-00681.pdf
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Autor*in
Kim, RayoungUniBi;
Mihailovic, Denis;
Riemann, Conrad JosefUniBi;
Kilgué, AlexanderUniBi;
Pfeiffer, ChristophUniBi;
Gehl, Hans-Björn;
Scholtz, Lars-UweUniBi;
Todt, IngoUniBi
Abstract / Bemerkung
Objectives: To study the correlation between positive cochlin tomoprotein testing (CTP), magnetic resonance (MR) imaging, and the auditory and vestibular function amongst patients with sudden hearing loss. Study Design: Prospective case series. Methods: We prospectively examined eight patients who presented with sudden hearing loss (>60 dB) with or without vertigo or tinnitus. We performed an ELISA-based CTP detection test using middle ear lavage samples. In addition to the CTP examination, a magnetic resonance imaging (MRI) examination was performed using different sequences (T1 and a T1 sequence with a contrast medium (CM), a T2 sequence, 4 h delayed intravenous gadolinium-enhanced three-dimensional fluid-attenuated inversion recovery (3D FLAIR)). Results: All patients with sudden hearing loss (>60 dB) presented a non-specific contrast enhancement in the cochlea and vestibulum on the affected side on delayed 3D-FLAIR MRI. Four patients had a positive CTP test, suggesting a perilymphatic fistula (PLF). However, no specific MRI signal for a PLF was observed. Conclusions: Using multimodal diagnostic measures, such as CTP testing and different MRI sequences, no correlation could be found in patients with a PLF.
Stichworte
magnetic resonance imaging;
4 h delayed intravenous gadolinium-enhanced;
3D FLAIR MRI;
cochlin tomoprotein;
sudden hearing loss;
perilymphatic;
fistula
Erscheinungsjahr
2024
Zeitschriftentitel
Brain Sciences
Band
14
Ausgabe
7
Art.-Nr.
681
Urheberrecht / Lizenzen
eISSN
2076-3425
Finanzierungs-Informationen
Open-Access-Publikationskosten wurden durch die Universität Bielefeld gefördert.
Page URI
https://pub.uni-bielefeld.de/record/2991674
Zitieren
Kim R, Mihailovic D, Riemann CJ, et al. MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss. Brain Sciences . 2024;14(7): 681.
Kim, R., Mihailovic, D., Riemann, C. J., Kilgué, A., Pfeiffer, C., Gehl, H. - B., Scholtz, L. - U., et al. (2024). MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss. Brain Sciences , 14(7), 681. https://doi.org/10.3390/brainsci14070681
Kim, Rayoung, Mihailovic, Denis, Riemann, Conrad Josef, Kilgué, Alexander, Pfeiffer, Christoph, Gehl, Hans-Björn, Scholtz, Lars-Uwe, and Todt, Ingo. 2024. “MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss”. Brain Sciences 14 (7): 681.
Kim, R., Mihailovic, D., Riemann, C. J., Kilgué, A., Pfeiffer, C., Gehl, H. - B., Scholtz, L. - U., and Todt, I. (2024). MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss. Brain Sciences 14:681.
Kim, R., et al., 2024. MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss. Brain Sciences , 14(7): 681.
R. Kim, et al., “MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss”, Brain Sciences , vol. 14, 2024, : 681.
Kim, R., Mihailovic, D., Riemann, C.J., Kilgué, A., Pfeiffer, C., Gehl, H.-B., Scholtz, L.-U., Todt, I.: MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss. Brain Sciences . 14, : 681 (2024).
Kim, Rayoung, Mihailovic, Denis, Riemann, Conrad Josef, Kilgué, Alexander, Pfeiffer, Christoph, Gehl, Hans-Björn, Scholtz, Lars-Uwe, and Todt, Ingo. “MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss”. Brain Sciences 14.7 (2024): 681.
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