Iridoid and irido-alkaloids from the fruits of<i> Mitragyna</i><i> stipulosa,</i> and the plausible biosynthetic route to the new ring formation

Ndoumbe CMM, Nono RN, Zeutsop JF, Bitchagno GTM, Lenta BN, Nkeng-Efouet-Alango P, Sewald N, Chouna JR (2023)
Biochemical Systematics and Ecology 111: 104732.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Ndoumbe, Christian Martial Mileng; Nono, Raymond Ngansop; Zeutsop, Jean Francois; Bitchagno, Gabin Thierry Mbahbou; Lenta, Bruno Ndjakou; Nkeng-Efouet-Alango, Pepin; Sewald, NorbertUniBi ; Chouna, Jean RodolpheUniBi
Abstract / Bemerkung
Mitragynoid (1), a new iridoid along with twelve known natural derivatives (2-13) were isolated from the fruits of Mitragyna stipulosa. In addition, three likely-artifact irido-alkaloids, mitrageines A-C (14-16) and gentianine (17) probably formed during the alkaloids extraction process were also isolated. The structures of compounds were established by means of spectroscopic method including IR, 1D and 2D NMR and mass spectrometric analysis. The biosynthetic route to the new ring formation was also proposed.
Stichworte
Mitragyna stipulosa; Rubiaceae; Iridoid-dimer; Artifacts alkaloid; Biosynthetic route
Erscheinungsjahr
2023
Zeitschriftentitel
Biochemical Systematics and Ecology
Band
111
Art.-Nr.
104732
ISSN
0305-1978
eISSN
1873-2925
Page URI
https://pub.uni-bielefeld.de/record/2984090

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Ndoumbe CMM, Nono RN, Zeutsop JF, et al. Iridoid and irido-alkaloids from the fruits of<i> Mitragyna</i><i> stipulosa,</i> and the plausible biosynthetic route to the new ring formation. Biochemical Systematics and Ecology. 2023;111: 104732.
Ndoumbe, C. M. M., Nono, R. N., Zeutsop, J. F., Bitchagno, G. T. M., Lenta, B. N., Nkeng-Efouet-Alango, P., Sewald, N., et al. (2023). Iridoid and irido-alkaloids from the fruits of<i> Mitragyna</i><i> stipulosa,</i> and the plausible biosynthetic route to the new ring formation. Biochemical Systematics and Ecology, 111, 104732. https://doi.org/10.1016/j.bse.2023.104732
Ndoumbe, Christian Martial Mileng, Nono, Raymond Ngansop, Zeutsop, Jean Francois, Bitchagno, Gabin Thierry Mbahbou, Lenta, Bruno Ndjakou, Nkeng-Efouet-Alango, Pepin, Sewald, Norbert, and Chouna, Jean Rodolphe. 2023. “Iridoid and irido-alkaloids from the fruits of<i> Mitragyna</i><i> stipulosa,</i> and the plausible biosynthetic route to the new ring formation”. Biochemical Systematics and Ecology 111: 104732.
Ndoumbe, C. M. M., Nono, R. N., Zeutsop, J. F., Bitchagno, G. T. M., Lenta, B. N., Nkeng-Efouet-Alango, P., Sewald, N., and Chouna, J. R. (2023). Iridoid and irido-alkaloids from the fruits of<i> Mitragyna</i><i> stipulosa,</i> and the plausible biosynthetic route to the new ring formation. Biochemical Systematics and Ecology 111:104732.
Ndoumbe, C.M.M., et al., 2023. Iridoid and irido-alkaloids from the fruits of<i> Mitragyna</i><i> stipulosa,</i> and the plausible biosynthetic route to the new ring formation. Biochemical Systematics and Ecology, 111: 104732.
C.M.M. Ndoumbe, et al., “Iridoid and irido-alkaloids from the fruits of<i> Mitragyna</i><i> stipulosa,</i> and the plausible biosynthetic route to the new ring formation”, Biochemical Systematics and Ecology, vol. 111, 2023, : 104732.
Ndoumbe, C.M.M., Nono, R.N., Zeutsop, J.F., Bitchagno, G.T.M., Lenta, B.N., Nkeng-Efouet-Alango, P., Sewald, N., Chouna, J.R.: Iridoid and irido-alkaloids from the fruits of<i> Mitragyna</i><i> stipulosa,</i> and the plausible biosynthetic route to the new ring formation. Biochemical Systematics and Ecology. 111, : 104732 (2023).
Ndoumbe, Christian Martial Mileng, Nono, Raymond Ngansop, Zeutsop, Jean Francois, Bitchagno, Gabin Thierry Mbahbou, Lenta, Bruno Ndjakou, Nkeng-Efouet-Alango, Pepin, Sewald, Norbert, and Chouna, Jean Rodolphe. “Iridoid and irido-alkaloids from the fruits of<i> Mitragyna</i><i> stipulosa,</i> and the plausible biosynthetic route to the new ring formation”. Biochemical Systematics and Ecology 111 (2023): 104732.
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