Two new 30-norfriedelane triterpenes from Caloncoba glauca (P. Beauv.) Gilg (Achariaceae)

Ndoumbe Tamba, Charlemagne; Tsopgni, Willifred Dongmo Tekapi; Fotso, Bernard Samuel Hodjie; Longue Ekon, Jean Pierre; Foundikou Nsangou, Mohamed; Ngo Nyobe, Judith Caroline; Sewald, Norbert; Ndom, Jean Claude

Two new 30-norfriedelane triterpenes from Caloncoba glauca (P. Beauv.) Gilg (Achariaceae)

Ndoumbe Tamba C, Tsopgni WDT, Fotso BSH, Longue Ekon JP, Foundikou Nsangou M, Ngo Nyobe JC, Sewald N, Ndom JC (2023)
Natural Product Research .

Zeitschriftenaufsatz | E-Veröff. vor dem Druck | Englisch

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DOI

https://doi.org/10.1080/14786419.2023.2248351

Autor*in

Ndoumbe Tamba, Charlemagne; Tsopgni, Willifred Dongmo Tekapi; Fotso, Bernard Samuel Hodjie; Longue Ekon, Jean Pierre; Foundikou Nsangou, Mohamed; Ngo Nyobe, Judith Caroline; Sewald, Norbert^UniBi ; Ndom, Jean Claude

Einrichtung

Fakultät für Chemie > Organische Chemie III

Abstract / Bemerkung

The chemical investigation of the methanolic root extract of Caloncoba glauca (P. Beauv.) Gilg exhibited two new 30-norfriedelane triterpenes, glaucalactones A and B (1-2), together with eight known compounds, caloncobalactone (3), friedelin (4), friedelanol (5), 3-oxo-friedelan-28-oic acid (6), stigmasterol (7), beta-sitosterol (8), beta-sitosterol-3-O-beta-D-glucopyranoside (9) and pentacosanoic acid (10). The structures of the isolates were elucidated by extensive spectroscopic and spectrometric analyses (1D and 2D NMR, ESI-MS) and by comparison with previously reported data. All the compounds were tested for their antioxidant, antifungal and antibacterial activities. Compound 1 displayed weak antibacterial effect with MIC value of 125mug/mL against Staphylococcus aureus and Escherishia coli. Compound 6 exhibited moderated antifungal activity against Candida krusei with MIC value of 62.5mug/mL. All the isolates were found to be inactive as antioxidants in the DPPH, ABTS and FRAP assays.

Erscheinungsjahr

2023

Zeitschriftentitel

Natural Product Research

eISSN

1478-6427

Page URI

https://pub.uni-bielefeld.de/record/2982552

Zitieren

Ndoumbe Tamba C, Tsopgni WDT, Fotso BSH, et al. Two new 30-norfriedelane triterpenes from Caloncoba glauca (P. Beauv.) Gilg (Achariaceae). Natural Product Research . 2023.

Ndoumbe Tamba, C., Tsopgni, W. D. T., Fotso, B. S. H., Longue Ekon, J. P., Foundikou Nsangou, M., Ngo Nyobe, J. C., Sewald, N., et al. (2023). Two new 30-norfriedelane triterpenes from Caloncoba glauca (P. Beauv.) Gilg (Achariaceae). Natural Product Research . https://doi.org/10.1080/14786419.2023.2248351

Ndoumbe Tamba, Charlemagne, Tsopgni, Willifred Dongmo Tekapi, Fotso, Bernard Samuel Hodjie, Longue Ekon, Jean Pierre, Foundikou Nsangou, Mohamed, Ngo Nyobe, Judith Caroline, Sewald, Norbert, and Ndom, Jean Claude. 2023. “Two new 30-norfriedelane triterpenes from Caloncoba glauca (P. Beauv.) Gilg (Achariaceae)”. Natural Product Research .

Ndoumbe Tamba, C., Tsopgni, W. D. T., Fotso, B. S. H., Longue Ekon, J. P., Foundikou Nsangou, M., Ngo Nyobe, J. C., Sewald, N., and Ndom, J. C. (2023). Two new 30-norfriedelane triterpenes from Caloncoba glauca (P. Beauv.) Gilg (Achariaceae). Natural Product Research .

Ndoumbe Tamba, C., et al., 2023. Two new 30-norfriedelane triterpenes from Caloncoba glauca (P. Beauv.) Gilg (Achariaceae). Natural Product Research .

C. Ndoumbe Tamba, et al., “Two new 30-norfriedelane triterpenes from Caloncoba glauca (P. Beauv.) Gilg (Achariaceae)”, Natural Product Research , 2023.

Ndoumbe Tamba, C., Tsopgni, W.D.T., Fotso, B.S.H., Longue Ekon, J.P., Foundikou Nsangou, M., Ngo Nyobe, J.C., Sewald, N., Ndom, J.C.: Two new 30-norfriedelane triterpenes from Caloncoba glauca (P. Beauv.) Gilg (Achariaceae). Natural Product Research . (2023).

Ndoumbe Tamba, Charlemagne, Tsopgni, Willifred Dongmo Tekapi, Fotso, Bernard Samuel Hodjie, Longue Ekon, Jean Pierre, Foundikou Nsangou, Mohamed, Ngo Nyobe, Judith Caroline, Sewald, Norbert, and Ndom, Jean Claude. “Two new 30-norfriedelane triterpenes from Caloncoba glauca (P. Beauv.) Gilg (Achariaceae)”. Natural Product Research (2023).

Daten bereitgestellt von European Bioinformatics Institute (EBI)