The Arabidopsis thaliana onset of leaf death 12 mutation in the lectin receptor kinase P2K2 results in an autoimmune phenotype

Zhao L, Wang H-J, Martins PD, van Dongen JT, Bolger AM, Schmidt R, Jing H-C, Mueller-Roeber B, Schippers JHM (2023)
BMC plant biology 23(1): 294.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
Download
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Autor*in
Zhao, Liming; Wang, Hao-Jie; Martins, Patricia Dalcin; van Dongen, Joost T; Bolger, Anthony M; Schmidt, RomyUniBi; Jing, Hai-Chun; Mueller-Roeber, Bernd; Schippers, Jos H M
Abstract / Bemerkung
BACKGROUND: Plant immunity relies on the perception of immunogenic signals by cell-surface and intracellular receptors and subsequent activation of defense responses like programmed cell death. Under certain circumstances, the fine-tuned innate immune system of plants results in the activation of autoimmune responses that cause constitutive defense responses and spontaneous cell death in the absence of pathogens.; RESULTS: Here, we characterized the onset of leaf death 12 (old12) mutant that was identified in the Arabidopsis accession Landsberg erecta. The old12 mutant is characterized by a growth defect, spontaneous cell death, plant-defense gene activation, and early senescence. In addition, the old12 phenotype is temperature reversible, thereby exhibiting all characteristics of an autoimmune mutant. Mapping the mutated locus revealed that the old12 phenotype is caused by a mutation in the Lectin Receptor Kinase P2-TYPE PURINERGIC RECEPTOR 2 (P2K2) gene. Interestingly, the P2K2 allele from Landsberg erecta is conserved among Brassicaceae. P2K2 has been implicated in pathogen tolerance and sensing extracellular ATP. The constitutive activation of defense responses in old12 results in improved resistance against Pseudomonas syringae pv. tomato DC3000.; CONCLUSION: We demonstrate that old12 is an auto-immune mutant and that allelic variation of P2K2 contributes to diversity in Arabidopsis immune responses. © 2023. The Author(s).
Erscheinungsjahr
2023
Zeitschriftentitel
BMC plant biology
Band
23
Ausgabe
1
Art.-Nr.
294
eISSN
1471-2229
Page URI
https://pub.uni-bielefeld.de/record/2979867

Zitieren

Zhao L, Wang H-J, Martins PD, et al. The Arabidopsis thaliana onset of leaf death 12 mutation in the lectin receptor kinase P2K2 results in an autoimmune phenotype. BMC plant biology. 2023;23(1): 294.
Zhao, L., Wang, H. - J., Martins, P. D., van Dongen, J. T., Bolger, A. M., Schmidt, R., Jing, H. - C., et al. (2023). The Arabidopsis thaliana onset of leaf death 12 mutation in the lectin receptor kinase P2K2 results in an autoimmune phenotype. BMC plant biology, 23(1), 294. https://doi.org/10.1186/s12870-023-04300-0
Zhao, Liming, Wang, Hao-Jie, Martins, Patricia Dalcin, van Dongen, Joost T, Bolger, Anthony M, Schmidt, Romy, Jing, Hai-Chun, Mueller-Roeber, Bernd, and Schippers, Jos H M. 2023. “The Arabidopsis thaliana onset of leaf death 12 mutation in the lectin receptor kinase P2K2 results in an autoimmune phenotype”. BMC plant biology 23 (1): 294.
Zhao, L., Wang, H. - J., Martins, P. D., van Dongen, J. T., Bolger, A. M., Schmidt, R., Jing, H. - C., Mueller-Roeber, B., and Schippers, J. H. M. (2023). The Arabidopsis thaliana onset of leaf death 12 mutation in the lectin receptor kinase P2K2 results in an autoimmune phenotype. BMC plant biology 23:294.
Zhao, L., et al., 2023. The Arabidopsis thaliana onset of leaf death 12 mutation in the lectin receptor kinase P2K2 results in an autoimmune phenotype. BMC plant biology, 23(1): 294.
L. Zhao, et al., “The Arabidopsis thaliana onset of leaf death 12 mutation in the lectin receptor kinase P2K2 results in an autoimmune phenotype”, BMC plant biology, vol. 23, 2023, : 294.
Zhao, L., Wang, H.-J., Martins, P.D., van Dongen, J.T., Bolger, A.M., Schmidt, R., Jing, H.-C., Mueller-Roeber, B., Schippers, J.H.M.: The Arabidopsis thaliana onset of leaf death 12 mutation in the lectin receptor kinase P2K2 results in an autoimmune phenotype. BMC plant biology. 23, : 294 (2023).
Zhao, Liming, Wang, Hao-Jie, Martins, Patricia Dalcin, van Dongen, Joost T, Bolger, Anthony M, Schmidt, Romy, Jing, Hai-Chun, Mueller-Roeber, Bernd, and Schippers, Jos H M. “The Arabidopsis thaliana onset of leaf death 12 mutation in the lectin receptor kinase P2K2 results in an autoimmune phenotype”. BMC plant biology 23.1 (2023): 294.
Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®
Quellen

PMID: 37264342
PubMed | Europe PMC

Suchen in

Google Scholar