P32: a sex- and gender-sensitive model for evidence-based precision medicine: from knowledge generation to implementation in the field of kidney transplantation
Sapir-Pichhadze R, Oertelt-Prigione S (2023)
Kidney International 103(4): 674-685.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
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Autor*in
Sapir-Pichhadze, Ruth;
Oertelt-Prigione, SabineUniBi ![](https://pub.uni-bielefeld.de/images/icon_orcid.png)
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Abstract / Bemerkung
Precision medicine emerged as a promising approach to identify suitable interventions for individual patients with a particular health concern and at various time points. Technology can enable the acquisition of increasing volumes of clinical and "omics" data at the individual and population levels and support advanced clinical decision making. However, to keep pace with evolving societal realities and developments, it is important to systematically include sex-and gender-specific considerations in the research process, from the acquisition of knowledge to implementation. Building on the foundations of evidence-based medicine and existing precision medicine frameworks, we propose a novel evidence-based precision medicine framework in the form of the P32 model, which considers individual sex-related (predictive [P1], preventive [P2], and personalized [P3] medicine) and gender-related (participatory [P4], psychosocial [P5], and percipient [P6] medicine) domains and their intersection with ethnicity, geography, and other demographic and social variables, in addition to population, community, and public dimensions (population-informed [P7], partnered with community [P8], and public-engaging [P9] medicine, respectively). Through its ability to contextualize and reflect on societal realities and developments, our model is expected to promote consideration of diversity, equity, and inclusion principles and, thus, enrich science, increase reproducibility of research, and ensure its social impact.
Stichworte
evidence-based medicine;
gender;
kidney transplantation;
pa-tient;
engagement;
precision medicine;
sex
Erscheinungsjahr
2023
Zeitschriftentitel
Kidney International
Band
103
Ausgabe
4
Seite(n)
674-685
ISSN
0085-2538
eISSN
1523-1755
Page URI
https://pub.uni-bielefeld.de/record/2978308
Zitieren
Sapir-Pichhadze R, Oertelt-Prigione S. P32: a sex- and gender-sensitive model for evidence-based precision medicine: from knowledge generation to implementation in the field of kidney transplantation. Kidney International. 2023;103(4):674-685.
Sapir-Pichhadze, R., & Oertelt-Prigione, S. (2023). P32: a sex- and gender-sensitive model for evidence-based precision medicine: from knowledge generation to implementation in the field of kidney transplantation. Kidney International, 103(4), 674-685. https://doi.org/10.1016/j.kint.2022.12.026
Sapir-Pichhadze, Ruth, and Oertelt-Prigione, Sabine. 2023. “P32: a sex- and gender-sensitive model for evidence-based precision medicine: from knowledge generation to implementation in the field of kidney transplantation”. Kidney International 103 (4): 674-685.
Sapir-Pichhadze, R., and Oertelt-Prigione, S. (2023). P32: a sex- and gender-sensitive model for evidence-based precision medicine: from knowledge generation to implementation in the field of kidney transplantation. Kidney International 103, 674-685.
Sapir-Pichhadze, R., & Oertelt-Prigione, S., 2023. P32: a sex- and gender-sensitive model for evidence-based precision medicine: from knowledge generation to implementation in the field of kidney transplantation. Kidney International, 103(4), p 674-685.
R. Sapir-Pichhadze and S. Oertelt-Prigione, “P32: a sex- and gender-sensitive model for evidence-based precision medicine: from knowledge generation to implementation in the field of kidney transplantation”, Kidney International, vol. 103, 2023, pp. 674-685.
Sapir-Pichhadze, R., Oertelt-Prigione, S.: P32: a sex- and gender-sensitive model for evidence-based precision medicine: from knowledge generation to implementation in the field of kidney transplantation. Kidney International. 103, 674-685 (2023).
Sapir-Pichhadze, Ruth, and Oertelt-Prigione, Sabine. “P32: a sex- and gender-sensitive model for evidence-based precision medicine: from knowledge generation to implementation in the field of kidney transplantation”. Kidney International 103.4 (2023): 674-685.
Daten bereitgestellt von European Bioinformatics Institute (EBI)
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