How Does Dietary Intake Relate to Dispositional Optimism and Health-Related Quality of Life in Germline BRCA1/2 Mutation Carriers?

Esser A, Neirich L, Grill S, Bischoff SCC, Halle M, Siniatchkin M, Yahiaoui-Doktor M, Kiechle M, Lammert J (2023)
Nutrients 15(6): 1396.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
Download
OA 350.23 KB
Autor*in
Esser, Anne; Neirich, Leonie; Grill, Sabine; Bischoff, Stephan C. C.; Halle, Martin; Siniatchkin, MichaelUniBi; Yahiaoui-Doktor, Maryam; Kiechle, Marion; Lammert, Jacqueline
Abstract / Bemerkung
Background: The Mediterranean diet (MD) is an anti-inflammatory diet linked to improved health-related quality of life (HRQoL). Germline (g)BRCA1/2 mutation carriers have an increased risk of developing breast cancer and are often exposed to severe cancer treatments, thus the improvement of HRQoL is important. Little is known about the associations between dietary intake and HRQoL in this population. Methods: We included 312 gBRCA1/2 mutation carriers from an ongoing prospective randomized controlled lifestyle intervention trial. Baseline data from the EPIC food frequency questionnaire was used to calculate the dietary inflammatory index (DII), and adherence to MD was captured by the 14-item PREDIMED questionnaire. HRQoL was measured by the EORTC QLQ-C30 and LOT-R questionnaires. The presence of metabolic syndrome (MetS) was determined using anthropometric measurements, blood samples and vital parameters. Linear and logistic regression models were performed to assess the possible impact of diet and metabolic syndrome on HRQoL. Results: Women with a prior history of cancer (59.6%) reported lower DIIs than women without it (p = 0.011). A greater adherence to MD was associated with lower DII scores (p < 0.001) and reduced odds for metabolic syndrome (MetS) (p = 0.024). Women with a more optimistic outlook on life reported greater adherence to MD (p < 0.001), whereas a more pessimistic outlook on life increased the odds for MetS (OR = 1.15; p = 0.023). Conclusions: This is the first study in gBRCA1/2 mutation carriers that has linked MD, DII, and MetS to HRQoL. The long-term clinical implications of these findings are yet to be determined.
Stichworte
BRCA1; BRCA2; DII; Mediterranean diet; HRQoL; metabolic syndrome
Erscheinungsjahr
2023
Zeitschriftentitel
Nutrients
Band
15
Ausgabe
6
Art.-Nr.
1396
eISSN
2072-6643
Page URI
https://pub.uni-bielefeld.de/record/2978307

Zitieren

Esser A, Neirich L, Grill S, et al. How Does Dietary Intake Relate to Dispositional Optimism and Health-Related Quality of Life in Germline BRCA1/2 Mutation Carriers? Nutrients . 2023;15(6): 1396.
Esser, A., Neirich, L., Grill, S., Bischoff, S. C. C., Halle, M., Siniatchkin, M., Yahiaoui-Doktor, M., et al. (2023). How Does Dietary Intake Relate to Dispositional Optimism and Health-Related Quality of Life in Germline BRCA1/2 Mutation Carriers? Nutrients , 15(6), 1396. https://doi.org/10.3390/nu15061396
Esser, Anne, Neirich, Leonie, Grill, Sabine, Bischoff, Stephan C. C., Halle, Martin, Siniatchkin, Michael, Yahiaoui-Doktor, Maryam, Kiechle, Marion, and Lammert, Jacqueline. 2023. “How Does Dietary Intake Relate to Dispositional Optimism and Health-Related Quality of Life in Germline BRCA1/2 Mutation Carriers?”. Nutrients 15 (6): 1396.
Esser, A., Neirich, L., Grill, S., Bischoff, S. C. C., Halle, M., Siniatchkin, M., Yahiaoui-Doktor, M., Kiechle, M., and Lammert, J. (2023). How Does Dietary Intake Relate to Dispositional Optimism and Health-Related Quality of Life in Germline BRCA1/2 Mutation Carriers? Nutrients 15:1396.
Esser, A., et al., 2023. How Does Dietary Intake Relate to Dispositional Optimism and Health-Related Quality of Life in Germline BRCA1/2 Mutation Carriers? Nutrients , 15(6): 1396.
A. Esser, et al., “How Does Dietary Intake Relate to Dispositional Optimism and Health-Related Quality of Life in Germline BRCA1/2 Mutation Carriers?”, Nutrients , vol. 15, 2023, : 1396.
Esser, A., Neirich, L., Grill, S., Bischoff, S.C.C., Halle, M., Siniatchkin, M., Yahiaoui-Doktor, M., Kiechle, M., Lammert, J.: How Does Dietary Intake Relate to Dispositional Optimism and Health-Related Quality of Life in Germline BRCA1/2 Mutation Carriers? Nutrients . 15, : 1396 (2023).
Esser, Anne, Neirich, Leonie, Grill, Sabine, Bischoff, Stephan C. C., Halle, Martin, Siniatchkin, Michael, Yahiaoui-Doktor, Maryam, Kiechle, Marion, and Lammert, Jacqueline. “How Does Dietary Intake Relate to Dispositional Optimism and Health-Related Quality of Life in Germline BRCA1/2 Mutation Carriers?”. Nutrients 15.6 (2023): 1396.
Alle Dateien verfügbar unter der/den folgenden Lizenz(en):
Creative Commons Namensnennung 4.0 International Public License (CC-BY 4.0):
Volltext(e)
Access Level
OA Open Access
Zuletzt Hochgeladen
2024-01-19T10:22:11Z
MD5 Prüfsumme
949daa0ec4ed50190caf44ee5ccf4bb9


Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®
Quellen

PMID: 36986126
PubMed | Europe PMC

Suchen in

Google Scholar