Epidermal cytokines in murine cutaneous irritant responses

Effendy I, Löffler H, Maibach HI (2000)
Journal of Applied Toxicology 20(4): 335-341.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Effendy, IsaakUniBi ; Löffler, H; Maibach, HI
Abstract / Bemerkung
Investigations on cytokines in skin irritancy or non-immunological irritant contact dermatitis (ICD) should improve our understanding of their complex mechanism, Numerous studies showed, however, that similar epidermal cytokines have been detected in irritant and allergic reactions, suggesting a lack of specific cytokines that clearly differentiate allergic from irritant reactions even though the pathomechanisms between allergic contact dermatitis (ACD) and ICD are distinguished. Recent data, however, indicate that some mediators may be restricted to allergic responses (contact hypersensitivity). This could provide the impetus to study their implication on irritant reactions. We overview the epidermal cytokines involved in irritant responses compared to those in contact hypersensitivity based on published results of studies using in vitro cell-cultured murine keratinocytes and in vivo murine models. Copyright (C) 2000 John Wiley & Sons, Ltd.
Stichworte
irritant contact dermatitis; skin irritation; UV radiation; skin; stripping; contact hypersensitivity
Erscheinungsjahr
2000
Zeitschriftentitel
Journal of Applied Toxicology
Band
20
Ausgabe
4
Seite(n)
335-341
ISSN
0260-437X
eISSN
1099-1263
Page URI
https://pub.uni-bielefeld.de/record/2968809

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Effendy I, Löffler H, Maibach HI. Epidermal cytokines in murine cutaneous irritant responses. Journal of Applied Toxicology . 2000;20(4):335-341.
Effendy, I., Löffler, H., & Maibach, H. I. (2000). Epidermal cytokines in murine cutaneous irritant responses. Journal of Applied Toxicology , 20(4), 335-341. https://doi.org/10.1002/1099-1263(200007/08)20:4<335::AID-JAT698>3.0.CO;2-L
Effendy, Isaak, Löffler, H, and Maibach, HI. 2000. “Epidermal cytokines in murine cutaneous irritant responses”. Journal of Applied Toxicology 20 (4): 335-341.
Effendy, I., Löffler, H., and Maibach, H. I. (2000). Epidermal cytokines in murine cutaneous irritant responses. Journal of Applied Toxicology 20, 335-341.
Effendy, I., Löffler, H., & Maibach, H.I., 2000. Epidermal cytokines in murine cutaneous irritant responses. Journal of Applied Toxicology , 20(4), p 335-341.
I. Effendy, H. Löffler, and H.I. Maibach, “Epidermal cytokines in murine cutaneous irritant responses”, Journal of Applied Toxicology , vol. 20, 2000, pp. 335-341.
Effendy, I., Löffler, H., Maibach, H.I.: Epidermal cytokines in murine cutaneous irritant responses. Journal of Applied Toxicology . 20, 335-341 (2000).
Effendy, Isaak, Löffler, H, and Maibach, HI. “Epidermal cytokines in murine cutaneous irritant responses”. Journal of Applied Toxicology 20.4 (2000): 335-341.
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PMID: 10942909
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