The influence of body mass index on skin susceptibility to sodium lauryl sulphate

Löffler H, Aramaki JUN, Effendy I (2002)
Skin Research and Technology 8(1): 19-22.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Löffler, H; Aramaki, JUN; Effendy, IsaakUniBi
Abstract / Bemerkung
Background: The influence of nutrition on the physiological functions of man is well studied. Numerous diseases can be exacerbated by obesity. However, it has not yet been determined whether body weight and body mass index (BMI), as an indicator of a high body fat store, can influence skin sensitivity. Objective: This study investigates the correlation between body mass index and the epidermal functions, evaluated by bioengineering methods, before and after an irritant patch test with sodium lauryl sulphate (SLS). Methods: Epidermal functions were evaluated using an evaporimeter, chromameter and laser-Doppler-flowmeter. Patch testing was conducted for 48h with two different concentrations of SLS (0.25% and 0.5%) on the forearms of healthy volunteers. Measurements were performed 24h after patch removal. Results: Obese individuals showed significantly increased transepidermal water loss (TEWL), skin blood flow and skin colour (red) as compared to a control group. However, the degree of skin sensitivity to SLS was not correlated with BMI. Conclusion: Basal biophysical parameters of the skin are primarily correlated with the BMI. This may be caused by obesity-induced physiological changes, e.g. increased sweat gland activity, high blood pressure and physiological temperature-regulating system. The epidermal barrier function, as evaluated after SLS patch testing is, however, not correlated with a high BMI, indicating a normal skin barrier.
Stichworte
skin sensitivity; transepidermal water loss; irritant contact dermatits; skin barrier
Erscheinungsjahr
2002
Zeitschriftentitel
Skin Research and Technology
Band
8
Ausgabe
1
Seite(n)
19-22
ISSN
0909-752X
eISSN
1600-0846
Page URI
https://pub.uni-bielefeld.de/record/2968797

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Löffler H, Aramaki JUN, Effendy I. The influence of body mass index on skin susceptibility to sodium lauryl sulphate. Skin Research and Technology. 2002;8(1):19-22.
Löffler, H., Aramaki, J. U. N., & Effendy, I. (2002). The influence of body mass index on skin susceptibility to sodium lauryl sulphate. Skin Research and Technology, 8(1), 19-22. https://doi.org/10.1046/j.0909-752x
Löffler, H, Aramaki, JUN, and Effendy, Isaak. 2002. “The influence of body mass index on skin susceptibility to sodium lauryl sulphate”. Skin Research and Technology 8 (1): 19-22.
Löffler, H., Aramaki, J. U. N., and Effendy, I. (2002). The influence of body mass index on skin susceptibility to sodium lauryl sulphate. Skin Research and Technology 8, 19-22.
Löffler, H., Aramaki, J.U.N., & Effendy, I., 2002. The influence of body mass index on skin susceptibility to sodium lauryl sulphate. Skin Research and Technology, 8(1), p 19-22.
H. Löffler, J.U.N. Aramaki, and I. Effendy, “The influence of body mass index on skin susceptibility to sodium lauryl sulphate”, Skin Research and Technology, vol. 8, 2002, pp. 19-22.
Löffler, H., Aramaki, J.U.N., Effendy, I.: The influence of body mass index on skin susceptibility to sodium lauryl sulphate. Skin Research and Technology. 8, 19-22 (2002).
Löffler, H, Aramaki, JUN, and Effendy, Isaak. “The influence of body mass index on skin susceptibility to sodium lauryl sulphate”. Skin Research and Technology 8.1 (2002): 19-22.
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