Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for and Nonsteroidal Anti‐Inflammatory Drugs
Theken KN, Lee CR, Gong L, Caudle KE, Formea CM, Gaedigk A, Klein TE, Agúndez JAG, Grosser T (2020)
Clinical Pharmacology & Therapeutics 108(2): 191-200.
Zeitschriftenaufsatz
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Autor*in
Theken, Katherine N.;
Lee, Craig R.;
Gong, Li;
Caudle, Kelly E.;
Formea, Christine M.;
Gaedigk, Andrea;
Klein, Teri E.;
Agúndez, José A.G.;
Grosser, TiloUniBi 
Abstract / Bemerkung
Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used analgesics due to their lack of addictive potential. However, NSAIDs have the potential to cause serious gastrointestinal, renal, and cardiovascular adverse events. CYP2C9 polymorphisms influence metabolism and clearance of several drugs in this class, thereby affecting drug exposure and potentially safety. We summarize evidence from the published literature supporting these associations and provide therapeutic recommendations for NSAIDs based on CYP2C9 genotype (updates at www.cpicpgx.org).
Erscheinungsjahr
2020
Zeitschriftentitel
Clinical Pharmacology & Therapeutics
Band
108
Ausgabe
2
Seite(n)
191-200
ISSN
0009-9236
eISSN
1532-6535
Page URI
https://pub.uni-bielefeld.de/record/2965302
Zitieren
Theken KN, Lee CR, Gong L, et al. Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for and Nonsteroidal Anti‐Inflammatory Drugs. Clinical Pharmacology & Therapeutics. 2020;108(2):191-200.
Theken, K. N., Lee, C. R., Gong, L., Caudle, K. E., Formea, C. M., Gaedigk, A., Klein, T. E., et al. (2020). Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for and Nonsteroidal Anti‐Inflammatory Drugs. Clinical Pharmacology & Therapeutics, 108(2), 191-200. https://doi.org/10.1002/cpt.1830
Theken, Katherine N., Lee, Craig R., Gong, Li, Caudle, Kelly E., Formea, Christine M., Gaedigk, Andrea, Klein, Teri E., Agúndez, José A.G., and Grosser, Tilo. 2020. “Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for and Nonsteroidal Anti‐Inflammatory Drugs”. Clinical Pharmacology & Therapeutics 108 (2): 191-200.
Theken, K. N., Lee, C. R., Gong, L., Caudle, K. E., Formea, C. M., Gaedigk, A., Klein, T. E., Agúndez, J. A. G., and Grosser, T. (2020). Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for and Nonsteroidal Anti‐Inflammatory Drugs. Clinical Pharmacology & Therapeutics 108, 191-200.
Theken, K.N., et al., 2020. Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for and Nonsteroidal Anti‐Inflammatory Drugs. Clinical Pharmacology & Therapeutics, 108(2), p 191-200.
K.N. Theken, et al., “Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for and Nonsteroidal Anti‐Inflammatory Drugs”, Clinical Pharmacology & Therapeutics, vol. 108, 2020, pp. 191-200.
Theken, K.N., Lee, C.R., Gong, L., Caudle, K.E., Formea, C.M., Gaedigk, A., Klein, T.E., Agúndez, J.A.G., Grosser, T.: Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for and Nonsteroidal Anti‐Inflammatory Drugs. Clinical Pharmacology & Therapeutics. 108, 191-200 (2020).
Theken, Katherine N., Lee, Craig R., Gong, Li, Caudle, Kelly E., Formea, Christine M., Gaedigk, Andrea, Klein, Teri E., Agúndez, José A.G., and Grosser, Tilo. “Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for and Nonsteroidal Anti‐Inflammatory Drugs”. Clinical Pharmacology & Therapeutics 108.2 (2020): 191-200.
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Daten bereitgestellt von Europe PubMed Central.
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