Acetaminophen, Nonsteroidal Anti-Inflammatory Drugs, and Hypertension
Spence JD, Grosser T, FitzGerald GA (2022)
Hypertension 79(9): 1922-1926.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
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Autor*in
Spence, J. David;
Grosser, TiloUniBi
;
FitzGerald, Garret A.
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Abstract / Bemerkung
Acetaminophen is widely regarded as a safe therapy for pain and fever in patients with cardiovascular disease and those taking anticoagulants. However, recent studies report that acetaminophen, like most other nonsteroidal anti-inflammatory drugs, increases blood pressure, and a formulation containing sodium increases cardiovascular risk. Those findings call into question guidelines recommending acetaminophen for patients with cardiovascular disease and pain, and those taking anticoagulants. We review evidence that acetaminophen has effects in common with nonsteroidal anti-inflammatory drugs, and its influence on coagulation via effects on vitamin K metabolism. Possible alternatives to acetaminophen for patients with pain are discussed.
Stichworte
Acetaminophen;
Paracetamol;
Cyclooxygenase
Erscheinungsjahr
2022
Zeitschriftentitel
Hypertension
Band
79
Ausgabe
9
Seite(n)
1922-1926
ISSN
0194-911X
eISSN
1524-4563
Page URI
https://pub.uni-bielefeld.de/record/2965293
Zitieren
Spence JD, Grosser T, FitzGerald GA. Acetaminophen, Nonsteroidal Anti-Inflammatory Drugs, and Hypertension. Hypertension. 2022;79(9):1922-1926.
Spence, J. D., Grosser, T., & FitzGerald, G. A. (2022). Acetaminophen, Nonsteroidal Anti-Inflammatory Drugs, and Hypertension. Hypertension, 79(9), 1922-1926. https://doi.org/10.1161/HYPERTENSIONAHA.122.19315
Spence, J. David, Grosser, Tilo, and FitzGerald, Garret A. 2022. “Acetaminophen, Nonsteroidal Anti-Inflammatory Drugs, and Hypertension”. Hypertension 79 (9): 1922-1926.
Spence, J. D., Grosser, T., and FitzGerald, G. A. (2022). Acetaminophen, Nonsteroidal Anti-Inflammatory Drugs, and Hypertension. Hypertension 79, 1922-1926.
Spence, J.D., Grosser, T., & FitzGerald, G.A., 2022. Acetaminophen, Nonsteroidal Anti-Inflammatory Drugs, and Hypertension. Hypertension, 79(9), p 1922-1926.
J.D. Spence, T. Grosser, and G.A. FitzGerald, “Acetaminophen, Nonsteroidal Anti-Inflammatory Drugs, and Hypertension”, Hypertension, vol. 79, 2022, pp. 1922-1926.
Spence, J.D., Grosser, T., FitzGerald, G.A.: Acetaminophen, Nonsteroidal Anti-Inflammatory Drugs, and Hypertension. Hypertension. 79, 1922-1926 (2022).
Spence, J. David, Grosser, Tilo, and FitzGerald, Garret A. “Acetaminophen, Nonsteroidal Anti-Inflammatory Drugs, and Hypertension”. Hypertension 79.9 (2022): 1922-1926.
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Daten bereitgestellt von European Bioinformatics Institute (EBI)
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Daten bereitgestellt von Europe PubMed Central.
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Daten bereitgestellt von Europe PubMed Central.
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