Functional correlates of distractor suppression during spatial working memory encoding

Toepper M, Gebhardt H, Beblo T, Thomas C, Driessen M, Bischoff M, Blecker CR, Vaitl D, Sammer G (2010)
Neuroscience 165(4): 1244-1253.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
Download
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Autor*in
Toepper, M.; Gebhardt, H.; Beblo, T.; Thomas, C.; Driessen, MartinUniBi ; Bischoff, M.; Blecker, C.R.; Vaitl, D.; Sammer, G.
Abstract / Bemerkung
Executive working memory operations are related to prefrontal regions in the healthy brain. Moreover, neuroimaging data provide evidence for a functional dissociation of ventrolateral and dorsolateral prefrontal cortex. Most authors either suggest a modality-specific or a function-specific prefrontal cortex organization. In the present study we particularly aimed at the identification of different prefrontal cerebral areas that are involved in executive inhibitory processes during spatial working memory encoding. In an fMRI study (functional magnetic resonance imaging) we examined the neural correlates of spatial working memory processing by varying the amount of executive demands of the task. Twenty healthy volunteers performed the Corsi Block-Tapping test (CBT) during fMRI. The CBT requires the storage and reproduction of spatial target sequences. In a second condition, we presented an adapted version of the Block-Suppression-Test (BST). The BST is based on the original CBT but additionally requires the active suppression of visual distraction within the target sequences. In comparison to the CBT performance, particularly the left dorsolateral prefrontal cortex (BA 9) showed more activity during the BST condition. Our results show that the left dorsolateral prefrontal cortex plays a crucial role for executive controlled inhibition of spatial distraction. Furthermore, our findings are in line with the processing model of a functional dorsolateral-ventrolateral prefrontal cortex organization.
Erscheinungsjahr
2010
Zeitschriftentitel
Neuroscience
Band
165
Ausgabe
4
Seite(n)
1244-1253
ISSN
03064522
Page URI
https://pub.uni-bielefeld.de/record/2963385

Zitieren

Toepper M, Gebhardt H, Beblo T, et al. Functional correlates of distractor suppression during spatial working memory encoding. Neuroscience. 2010;165(4):1244-1253.
Toepper, M., Gebhardt, H., Beblo, T., Thomas, C., Driessen, M., Bischoff, M., Blecker, C. R., et al. (2010). Functional correlates of distractor suppression during spatial working memory encoding. Neuroscience, 165(4), 1244-1253. https://doi.org/10.1016/j.neuroscience.2009.11.019
Toepper, M., Gebhardt, H., Beblo, T., Thomas, C., Driessen, M., Bischoff, M., Blecker, C. R., Vaitl, D., and Sammer, G. (2010). Functional correlates of distractor suppression during spatial working memory encoding. Neuroscience 165, 1244-1253.
Toepper, M., et al., 2010. Functional correlates of distractor suppression during spatial working memory encoding. Neuroscience, 165(4), p 1244-1253.
M. Toepper, et al., “Functional correlates of distractor suppression during spatial working memory encoding”, Neuroscience, vol. 165, 2010, pp. 1244-1253.
Toepper, M., Gebhardt, H., Beblo, T., Thomas, C., Driessen, M., Bischoff, M., Blecker, C.R., Vaitl, D., Sammer, G.: Functional correlates of distractor suppression during spatial working memory encoding. Neuroscience. 165, 1244-1253 (2010).
Toepper, M., Gebhardt, H., Beblo, T., Thomas, C., Driessen, Martin, Bischoff, M., Blecker, C.R., Vaitl, D., and Sammer, G. “Functional correlates of distractor suppression during spatial working memory encoding”. Neuroscience 165.4 (2010): 1244-1253.

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 19925856
PubMed | Europe PMC

Suchen in

Google Scholar