Multichannel anodal tDCS over the left dorsolateral prefrontal cortex in a paediatric population

Splittgerber M, Borzikowsky C, Salvador R, Puonti O, Papadimitriou K, Merschformann C, Biagi MC, Stenner T, Brauer H, Breitling-Ziegler C, Prehn-Kristensen A, et al. (2021)
Scientific Reports 11(1): 21512.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
Download
OA 2.75 MB
Autor*in
Splittgerber, Maike; Borzikowsky, Christoph; Salvador, Ricardo; Puonti, Oula; Papadimitriou, Kiriaki; Merschformann, Christoph; Biagi, Maria Chiara; Stenner, Tristan; Brauer, Hannah; Breitling-Ziegler, Carolin; Prehn-Kristensen, Alexander; Krauel, Kerstin
Alle
Abstract / Bemerkung
Methodological studies investigating transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex (lDLPFC) in paediatric populations are limited. Therefore, we investigated in a paediatric population whether stimulation success of multichannel tDCS over the lDLPFC depends on concurrent task performance and individual head anatomy. In a randomised, sham-controlled, double-blind crossover study 22 healthy participants (10-17 years) received 2 mA multichannel anodal tDCS (atDCS) over the lDLPFC with and without a 2-back working memory (WM) task. After stimulation, the 2-back task and a Flanker task were performed. Resting state and task-related EEG were recorded. In 16 participants we calculated the individual electric field (E-field) distribution. Performance and neurophysiological activity in the 2-back task were not affected by atDCS. atDCS reduced reaction times in the Flanker task, independent of whether atDCS had been combined with the 2-back task. Flanker task related beta oscillation increased following stimulation without 2-back task performance. atDCS effects were not correlated with the E-field. We found no effect of multichannel atDCS over the lDLPFC on WM in children/adolescents but a transfer effect on interference control. While this effect on behaviour was independent of concurrent task performance, neurophysiological activity might be more sensitive to cognitive activation during stimulation. However, our results are limited by the small sample size, the lack of an active control group and variations in WM performance.
Erscheinungsjahr
2021
Zeitschriftentitel
Scientific Reports
Band
11
Ausgabe
1
Art.-Nr.
21512
eISSN
2045-2322
Page URI
https://pub.uni-bielefeld.de/record/2959495

Zitieren

Splittgerber M, Borzikowsky C, Salvador R, et al. Multichannel anodal tDCS over the left dorsolateral prefrontal cortex in a paediatric population. Scientific Reports . 2021;11(1): 21512.
Splittgerber, M., Borzikowsky, C., Salvador, R., Puonti, O., Papadimitriou, K., Merschformann, C., Biagi, M. C., et al. (2021). Multichannel anodal tDCS over the left dorsolateral prefrontal cortex in a paediatric population. Scientific Reports , 11(1), 21512. https://doi.org/10.1038/s41598-021-00933-z
Splittgerber, Maike, Borzikowsky, Christoph, Salvador, Ricardo, Puonti, Oula, Papadimitriou, Kiriaki, Merschformann, Christoph, Biagi, Maria Chiara, et al. 2021. “Multichannel anodal tDCS over the left dorsolateral prefrontal cortex in a paediatric population”. Scientific Reports 11 (1): 21512.
Splittgerber, M., Borzikowsky, C., Salvador, R., Puonti, O., Papadimitriou, K., Merschformann, C., Biagi, M. C., Stenner, T., Brauer, H., Breitling-Ziegler, C., et al. (2021). Multichannel anodal tDCS over the left dorsolateral prefrontal cortex in a paediatric population. Scientific Reports 11:21512.
Splittgerber, M., et al., 2021. Multichannel anodal tDCS over the left dorsolateral prefrontal cortex in a paediatric population. Scientific Reports , 11(1): 21512.
M. Splittgerber, et al., “Multichannel anodal tDCS over the left dorsolateral prefrontal cortex in a paediatric population”, Scientific Reports , vol. 11, 2021, : 21512.
Splittgerber, M., Borzikowsky, C., Salvador, R., Puonti, O., Papadimitriou, K., Merschformann, C., Biagi, M.C., Stenner, T., Brauer, H., Breitling-Ziegler, C., Prehn-Kristensen, A., Krauel, K., Ruffini, G., Pedersen, A., Nees, F., Thielscher, A., Dempfle, A., Siniatchkin, M., Moliadze, V.: Multichannel anodal tDCS over the left dorsolateral prefrontal cortex in a paediatric population. Scientific Reports . 11, : 21512 (2021).
Splittgerber, Maike, Borzikowsky, Christoph, Salvador, Ricardo, Puonti, Oula, Papadimitriou, Kiriaki, Merschformann, Christoph, Biagi, Maria Chiara, Stenner, Tristan, Brauer, Hannah, Breitling-Ziegler, Carolin, Prehn-Kristensen, Alexander, Krauel, Kerstin, Ruffini, Giulio, Pedersen, Anya, Nees, Frauke, Thielscher, Axel, Dempfle, Astrid, Siniatchkin, Michael, and Moliadze, Vera. “Multichannel anodal tDCS over the left dorsolateral prefrontal cortex in a paediatric population”. Scientific Reports 11.1 (2021): 21512.
Alle Dateien verfügbar unter der/den folgenden Lizenz(en):
Creative Commons Namensnennung 4.0 International Public License (CC-BY 4.0):
Volltext(e)
Access Level
OA Open Access
Zuletzt Hochgeladen
2024-01-12T13:39:41Z
MD5 Prüfsumme
05b2186e3ce058fda14831ee80519dfb


Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

References

Daten bereitgestellt von Europe PubMed Central.

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®
Quellen

PMID: 34728684
PubMed | Europe PMC

Suchen in

Google Scholar