Pentacyclic triterpenoids and other constituents isolated from the leaves of Gambeya lacourtiana and their antibacterial activity

Talla RM, Jouda J-B, Mbazoa CD, Kapche GDWF, Lenta BN, Sewald N, Wandji J (2021)
Biochemical Systematics and Ecology 98: 104322.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Talla, Rostan Mangoua; Jouda, Jean-Bosco; Mbazoa, Céline Djama; Kapche, Gilbert Deccaux Wabo Fotso; Lenta, Bruno Ndjakou; Sewald, NorbertUniBi ; Wandji, Jean
Abstract / Bemerkung
The phytochemical study was done on the leaves of Gambeya lacourtiana. This plant has been used in traditional medicine to treat of different ailments such as uterine heamorrhage, metritis and other vaginal infections. Chromatographic fractionation and purification on the leaves crude extract afforded lupeol acetate (1), lupenone (2), lupeol (3), taraxerol (4) stigmasterol (5), erythrodiol (6), chamaedrydiol (7), methyl pheophorbide-a (8), corosolic acid (9), tormentic acid (10), epicatechin (11) and 22-dihydrospinasterol 3-O-β-D-glucopyranoside (12). The structures of compounds 1–12 were elucidated on the basis of 1D and 2D NMR, mass spectrometric and the spectroscopic data as well as comparison with the literature. Compounds 4, 7–10 and 12 were isolated for the first time from Gambeya genus. Crude extract, fractions and compounds 6–12 were evaluated for their antibacterial activity. Methyl pheophorbide-a (8) demonstrated moderate activity against Salmonella typhi CPC with MIC values of 62.5 μg/mL. The chemophenetic significance of these compounds is also discussed.
Erscheinungsjahr
2021
Zeitschriftentitel
Biochemical Systematics and Ecology
Band
98
Art.-Nr.
104322
ISSN
03051978
Page URI
https://pub.uni-bielefeld.de/record/2956522

Zitieren

Talla RM, Jouda J-B, Mbazoa CD, et al. Pentacyclic triterpenoids and other constituents isolated from the leaves of Gambeya lacourtiana and their antibacterial activity. Biochemical Systematics and Ecology. 2021;98: 104322.
Talla, R. M., Jouda, J. - B., Mbazoa, C. D., Kapche, G. D. W. F., Lenta, B. N., Sewald, N., & Wandji, J. (2021). Pentacyclic triterpenoids and other constituents isolated from the leaves of Gambeya lacourtiana and their antibacterial activity. Biochemical Systematics and Ecology, 98, 104322. https://doi.org/10.1016/j.bse.2021.104322
Talla, R. M., Jouda, J. - B., Mbazoa, C. D., Kapche, G. D. W. F., Lenta, B. N., Sewald, N., and Wandji, J. (2021). Pentacyclic triterpenoids and other constituents isolated from the leaves of Gambeya lacourtiana and their antibacterial activity. Biochemical Systematics and Ecology 98:104322.
Talla, R.M., et al., 2021. Pentacyclic triterpenoids and other constituents isolated from the leaves of Gambeya lacourtiana and their antibacterial activity. Biochemical Systematics and Ecology, 98: 104322.
R.M. Talla, et al., “Pentacyclic triterpenoids and other constituents isolated from the leaves of Gambeya lacourtiana and their antibacterial activity”, Biochemical Systematics and Ecology, vol. 98, 2021, : 104322.
Talla, R.M., Jouda, J.-B., Mbazoa, C.D., Kapche, G.D.W.F., Lenta, B.N., Sewald, N., Wandji, J.: Pentacyclic triterpenoids and other constituents isolated from the leaves of Gambeya lacourtiana and their antibacterial activity. Biochemical Systematics and Ecology. 98, : 104322 (2021).
Talla, Rostan Mangoua, Jouda, Jean-Bosco, Mbazoa, Céline Djama, Kapche, Gilbert Deccaux Wabo Fotso, Lenta, Bruno Ndjakou, Sewald, Norbert, and Wandji, Jean. “Pentacyclic triterpenoids and other constituents isolated from the leaves of Gambeya lacourtiana and their antibacterial activity”. Biochemical Systematics and Ecology 98 (2021): 104322.

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