Phytochemical, antibacterial, antioxidant and cytoxicity investigation of Tarenna grandiflora
Zeutsop JF, Nono RN, Frese M, Chouna JR, Lenta BN, Nkeng-Efouet-Alango P, Sewald N (2021)
Zeitschrift fur Naturforschung. C, Journal of biosciences 76(7-8): 285–290.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
Download
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Autor*in
Zeutsop, Jean Francois;
Nono, Raymond Ngansop;
Frese, MarcelUniBi
;
Chouna, Jean Rodolphe;
Lenta, Bruno Ndjakou;
Nkeng-Efouet-Alango, Pepin;
Sewald, NorbertUniBi ![](https://pub.uni-bielefeld.de/images/icon_orcid.png)
![](https://pub.uni-bielefeld.de/images/icon_orcid.png)
![](https://pub.uni-bielefeld.de/images/icon_orcid.png)
Einrichtung
Abstract / Bemerkung
The phytochemical investigation of Tarenna grandiflora led to the isolation of 18 known compounds ofwhich were four flavones, three anthraquinones, one phenyl propanoic derivative, five triterpenoids, four steroids and a mixture of glucose. Luteolin (1) and soranjidiol (6) were allylated and/or prenylated to give four new semisynthesized derivatives which were fully characterized as 7,3',4'-O-triallylluteolin (1a), luteolin-7,3',4'-O-triprenyls (1b), luteolin-5,7,3',4'-O-tetraprenyls (1c) and 6-O-allylsoranjidiol (6a). Their structures were established using spectroscopic analysis including 1D, 2D NMR and MS data. The cytotoxic, antioxidant and antimicrobial activities of extracts, fractions, isolated compounds and semi-synthesized derivatives were evaluated. The petroleum ether and EtOAc extracts exhibited good cytotoxic potency on KB-3-1cell line with IC50 of >0.1 and 0.025mg/mL respectively, while compounds 1b and 11 were the most active (IC50>0.0001M). Compounds 1 and 3 showed the best antioxidant activities (45.5 and 55.8M); while compounds 9 and 12 showed the best antibacterial activities with MICs values ranges from 8.55 to 132M. © 2020 Walter de Gruyter GmbH, Berlin/Boston.
Erscheinungsjahr
2021
Zeitschriftentitel
Zeitschrift fur Naturforschung. C, Journal of biosciences
Band
76
Ausgabe
7-8
Seite(n)
285–290
eISSN
1865-7125
Page URI
https://pub.uni-bielefeld.de/record/2956147
Zitieren
Zeutsop JF, Nono RN, Frese M, et al. Phytochemical, antibacterial, antioxidant and cytoxicity investigation of Tarenna grandiflora. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2021;76(7-8):285–290.
Zeutsop, J. F., Nono, R. N., Frese, M., Chouna, J. R., Lenta, B. N., Nkeng-Efouet-Alango, P., & Sewald, N. (2021). Phytochemical, antibacterial, antioxidant and cytoxicity investigation of Tarenna grandiflora. Zeitschrift fur Naturforschung. C, Journal of biosciences, 76(7-8), 285–290. https://doi.org/10.1515/znc-2020-0187
Zeutsop, Jean Francois, Nono, Raymond Ngansop, Frese, Marcel, Chouna, Jean Rodolphe, Lenta, Bruno Ndjakou, Nkeng-Efouet-Alango, Pepin, and Sewald, Norbert. 2021. “Phytochemical, antibacterial, antioxidant and cytoxicity investigation of Tarenna grandiflora”. Zeitschrift fur Naturforschung. C, Journal of biosciences 76 (7-8): 285–290.
Zeutsop, J. F., Nono, R. N., Frese, M., Chouna, J. R., Lenta, B. N., Nkeng-Efouet-Alango, P., and Sewald, N. (2021). Phytochemical, antibacterial, antioxidant and cytoxicity investigation of Tarenna grandiflora. Zeitschrift fur Naturforschung. C, Journal of biosciences 76, 285–290.
Zeutsop, J.F., et al., 2021. Phytochemical, antibacterial, antioxidant and cytoxicity investigation of Tarenna grandiflora. Zeitschrift fur Naturforschung. C, Journal of biosciences, 76(7-8), p 285–290.
J.F. Zeutsop, et al., “Phytochemical, antibacterial, antioxidant and cytoxicity investigation of Tarenna grandiflora”, Zeitschrift fur Naturforschung. C, Journal of biosciences, vol. 76, 2021, pp. 285–290.
Zeutsop, J.F., Nono, R.N., Frese, M., Chouna, J.R., Lenta, B.N., Nkeng-Efouet-Alango, P., Sewald, N.: Phytochemical, antibacterial, antioxidant and cytoxicity investigation of Tarenna grandiflora. Zeitschrift fur Naturforschung. C, Journal of biosciences. 76, 285–290 (2021).
Zeutsop, Jean Francois, Nono, Raymond Ngansop, Frese, Marcel, Chouna, Jean Rodolphe, Lenta, Bruno Ndjakou, Nkeng-Efouet-Alango, Pepin, and Sewald, Norbert. “Phytochemical, antibacterial, antioxidant and cytoxicity investigation of Tarenna grandiflora”. Zeitschrift fur Naturforschung. C, Journal of biosciences 76.7-8 (2021): 285–290.
Daten bereitgestellt von European Bioinformatics Institute (EBI)
Zitationen in Europe PMC
Daten bereitgestellt von Europe PubMed Central.
References
Daten bereitgestellt von Europe PubMed Central.
Export
Markieren/ Markierung löschen
Markierte Publikationen
Web of Science
Dieser Datensatz im Web of Science®Quellen
PMID: 34218550
PubMed | Europe PMC
Suchen in