Complete genome sequence of Streptomyces cyanogenus S136, producer of anticancer angucycline landomycin A

Hrab P, Rückert C, Busche T, Ostash I, Kalinowski J, Fedorenko V, Yushchuk O, Ostash B (2021)
3 Biotech 11(6): 282 .

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Hrab, Pavlo; Rückert, ChristianUniBi ; Busche, TobiasUniBi; Ostash, Iryna; Kalinowski, JörnUniBi; Fedorenko, Victor; Yushchuk, Oleksandr; Ostash, Bohdan
Abstract / Bemerkung
Streptomyces cyanogenus S136 is the only known producer of landomycin A (LaA), one of the founding members of angucycline family of aromatic polyketides. LaA displays potent anticancer activities which has made this natural product a target of numerous chemical and cell biological studies. Little is known about the potential of S136 strain to produce other secondary metabolites. Here we report complete genome sequence of LaA producer and how we used this sequence to evaluate for this species its phylogenetic position and diversity of gene clusters for natural product biosynthesis.; Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-021-02834-4. © King Abdulaziz City for Science and Technology 2021.
Erscheinungsjahr
2021
Zeitschriftentitel
3 Biotech
Band
11
Ausgabe
6
Art.-Nr.
282
ISSN
2190-572X
Page URI
https://pub.uni-bielefeld.de/record/2955527

Zitieren

Hrab P, Rückert C, Busche T, et al. Complete genome sequence of Streptomyces cyanogenus S136, producer of anticancer angucycline landomycin A. 3 Biotech. 2021;11(6): 282 .
Hrab, P., Rückert, C., Busche, T., Ostash, I., Kalinowski, J., Fedorenko, V., Yushchuk, O., et al. (2021). Complete genome sequence of Streptomyces cyanogenus S136, producer of anticancer angucycline landomycin A. 3 Biotech, 11(6), 282 . https://doi.org/10.1007/s13205-021-02834-4
Hrab, P., Rückert, C., Busche, T., Ostash, I., Kalinowski, J., Fedorenko, V., Yushchuk, O., and Ostash, B. (2021). Complete genome sequence of Streptomyces cyanogenus S136, producer of anticancer angucycline landomycin A. 3 Biotech 11:282 .
Hrab, P., et al., 2021. Complete genome sequence of Streptomyces cyanogenus S136, producer of anticancer angucycline landomycin A. 3 Biotech, 11(6): 282 .
P. Hrab, et al., “Complete genome sequence of Streptomyces cyanogenus S136, producer of anticancer angucycline landomycin A”, 3 Biotech, vol. 11, 2021, : 282 .
Hrab, P., Rückert, C., Busche, T., Ostash, I., Kalinowski, J., Fedorenko, V., Yushchuk, O., Ostash, B.: Complete genome sequence of Streptomyces cyanogenus S136, producer of anticancer angucycline landomycin A. 3 Biotech. 11, : 282 (2021).
Hrab, Pavlo, Rückert, Christian, Busche, Tobias, Ostash, Iryna, Kalinowski, Jörn, Fedorenko, Victor, Yushchuk, Oleksandr, and Ostash, Bohdan. “Complete genome sequence of Streptomyces cyanogenus S136, producer of anticancer angucycline landomycin A”. 3 Biotech 11.6 (2021): 282 .

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