Complete genome sequence of Streptomyces cyanogenus S136, producer of anticancer angucycline landomycin A

Hrab, Pavlo; Rückert, Christian; Busche, Tobias; Ostash, Iryna; Kalinowski, Jörn; Fedorenko, Victor; Yushchuk, Oleksandr; Ostash, Bohdan

Complete genome sequence of Streptomyces cyanogenus S136, producer of anticancer angucycline landomycin A

Hrab P, Rückert C, Busche T, Ostash I, Kalinowski J, Fedorenko V, Yushchuk O, Ostash B (2021)
3 Biotech 11(6): 282 .

Zeitschriftenaufsatz | Veröffentlicht | Englisch

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DOI

https://doi.org/10.1007/s13205-021-02834-4

Autor*in

Hrab, Pavlo; Rückert, Christian^UniBi ; Busche, Tobias^UniBi; Ostash, Iryna; Kalinowski, Jörn^UniBi; Fedorenko, Victor; Yushchuk, Oleksandr; Ostash, Bohdan

Einrichtung

Centrum für Biotechnologie

Abstract / Bemerkung

Streptomyces cyanogenus S136 is the only known producer of landomycin A (LaA), one of the founding members of angucycline family of aromatic polyketides. LaA displays potent anticancer activities which has made this natural product a target of numerous chemical and cell biological studies. Little is known about the potential of S136 strain to produce other secondary metabolites. Here we report complete genome sequence of LaA producer and how we used this sequence to evaluate for this species its phylogenetic position and diversity of gene clusters for natural product biosynthesis.; Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-021-02834-4. © King Abdulaziz City for Science and Technology 2021.

Erscheinungsjahr

2021

Zeitschriftentitel

3 Biotech

Band

Ausgabe

Art.-Nr.

282

ISSN

2190-572X

Page URI

https://pub.uni-bielefeld.de/record/2955527

Zitieren

Hrab P, Rückert C, Busche T, et al. Complete genome sequence of Streptomyces cyanogenus S136, producer of anticancer angucycline landomycin A. 3 Biotech. 2021;11(6): 282 .

Hrab, P., Rückert, C., Busche, T., Ostash, I., Kalinowski, J., Fedorenko, V., Yushchuk, O., et al. (2021). Complete genome sequence of Streptomyces cyanogenus S136, producer of anticancer angucycline landomycin A. 3 Biotech, 11(6), 282 . https://doi.org/10.1007/s13205-021-02834-4

Hrab, Pavlo, Rückert, Christian, Busche, Tobias, Ostash, Iryna, Kalinowski, Jörn, Fedorenko, Victor, Yushchuk, Oleksandr, and Ostash, Bohdan. 2021. “Complete genome sequence of Streptomyces cyanogenus S136, producer of anticancer angucycline landomycin A”. 3 Biotech 11 (6): 282 .

Hrab, P., Rückert, C., Busche, T., Ostash, I., Kalinowski, J., Fedorenko, V., Yushchuk, O., and Ostash, B. (2021). Complete genome sequence of Streptomyces cyanogenus S136, producer of anticancer angucycline landomycin A. 3 Biotech 11:282 .

Hrab, P., et al., 2021. Complete genome sequence of Streptomyces cyanogenus S136, producer of anticancer angucycline landomycin A. 3 Biotech, 11(6): 282 .

P. Hrab, et al., “Complete genome sequence of Streptomyces cyanogenus S136, producer of anticancer angucycline landomycin A”, 3 Biotech, vol. 11, 2021, : 282 .

Hrab, P., Rückert, C., Busche, T., Ostash, I., Kalinowski, J., Fedorenko, V., Yushchuk, O., Ostash, B.: Complete genome sequence of Streptomyces cyanogenus S136, producer of anticancer angucycline landomycin A. 3 Biotech. 11, : 282 (2021).

Hrab, Pavlo, Rückert, Christian, Busche, Tobias, Ostash, Iryna, Kalinowski, Jörn, Fedorenko, Victor, Yushchuk, Oleksandr, and Ostash, Bohdan. “Complete genome sequence of Streptomyces cyanogenus S136, producer of anticancer angucycline landomycin A”. 3 Biotech 11.6 (2021): 282 .

Daten bereitgestellt von European Bioinformatics Institute (EBI)