Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being

Wolf S, Becker J, Tsuge Y, Kawaguchi H, Kondo A, Marienhagen J, Bott M, Wendisch VF, Wittmann C (2021)
Essays in Biochemistry.

Zeitschriftenaufsatz | E-Veröff. vor dem Druck | Englisch
 
Download
OA 932.69 KB
Autor*in
Wolf, Sabrina; Becker, Judith; Tsuge, Yota; Kawaguchi, Hideo; Kondo, Akihiko; Marienhagen, Jan; Bott, Michael; Wendisch, Volker F.UniBi ; Wittmann, Christoph
Abstract / Bemerkung
The soil microbe Corynebacterium glutamicum is a leading workhorse in industrial biotechnology and has become famous for its power to synthetise amino acids and a range of bulk chemicals at high titre and yield. The product portfolio of the microbe is continuously expanding. Moreover, metabolically engineered strains of C. glutamicum produce more than 30 high value active ingredients, including signature molecules of raspberry, savoury, and orange flavours, sun blockers, anti-ageing sugars, and polymers for regenerative medicine. Herein, we highlight recent advances in engineering of the microbe into novel cell factories that overproduce these precious molecules from pioneering proofs-of-concept up to industrial productivity.
Erscheinungsjahr
2021
Zeitschriftentitel
Essays in Biochemistry
ISSN
0071-1365
eISSN
1744-1358
Page URI
https://pub.uni-bielefeld.de/record/2955387

Zitieren

Wolf S, Becker J, Tsuge Y, et al. Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being. Essays in Biochemistry. 2021.
Wolf, S., Becker, J., Tsuge, Y., Kawaguchi, H., Kondo, A., Marienhagen, J., Bott, M., et al. (2021). Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being. Essays in Biochemistry. https://doi.org/10.1042/EBC20200134
Wolf, S., Becker, J., Tsuge, Y., Kawaguchi, H., Kondo, A., Marienhagen, J., Bott, M., Wendisch, V. F., and Wittmann, C. (2021). Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being. Essays in Biochemistry.
Wolf, S., et al., 2021. Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being. Essays in Biochemistry.
S. Wolf, et al., “Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being”, Essays in Biochemistry, 2021.
Wolf, S., Becker, J., Tsuge, Y., Kawaguchi, H., Kondo, A., Marienhagen, J., Bott, M., Wendisch, V.F., Wittmann, C.: Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being. Essays in Biochemistry. (2021).
Wolf, Sabrina, Becker, Judith, Tsuge, Yota, Kawaguchi, Hideo, Kondo, Akihiko, Marienhagen, Jan, Bott, Michael, Wendisch, Volker F., and Wittmann, Christoph. “Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being”. Essays in Biochemistry (2021).
Alle Dateien verfügbar unter der/den folgenden Lizenz(en):
Creative Commons Namensnennung 4.0 International Public License (CC-BY 4.0):
Volltext(e)
Name
Access Level
OA Open Access
Zuletzt Hochgeladen
2021-06-07T15:37:24Z
MD5 Prüfsumme
0ae9090426c0ab1cdd369cdbd1b3e791

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Quellen

PMID: 34096577
PubMed | Europe PMC

Suchen in

Google Scholar