Health economic burden of patients with phenylketonuria (PKU) - A retrospective study of German health insurance claims data

Trefz F, Muntau AC, Schneider KM, Altevers J, Jacob C, Braun S, Greiner W, Jha A, Jain M, Alvarez I, Lane P, et al. (2021)
Molecular genetics and metabolism reports 27: 100764.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Trefz, Friedrich; Muntau, Ania C; Schneider, Kim M; Altevers, Julia; Jacob, Christian; Braun, Sebastian; Greiner, WolfgangUniBi; Jha, Ashok; Jain, Mohit; Alvarez, Ignacio; Lane, Paul; Zeiss, Claudia
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Abstract / Bemerkung
This retrospective matched-cohort analysis compared health-economic burdens of adults (≥18years; n=377) with phenylketonuria (PKU) and age/gender-matched non-PKU controls (n=3770) in Germany. Healthcare costs and resource-utilization were analyzed for the year 2015. Differences between groups were tested using 95% CI of mean differences (MD). PKU patients had significantly higher mean costs in total (MD 3307, 95% CI 1736-4879), for pharmaceuticals (MD 1912, 95% CI 1195-2629) [including dietary amino-acid supplements (MD 1268, 95% CI 864-1672)], and outpatient costs (MD 395, 95% CI 115-675). Inpatient costs (MD 904, 95% CI -293 to 2100) and costs for aids and remedies (MD 97, 95% CI -10 to 203) were also higher in PKU patients. PKU patients had more outpatient visits and stayed longer in hospital. Adult PKU patients incur higher total healthcare costs than non-PKU controls, especially regarding pharmaceuticals and outpatient costs, and more frequent resource-utilization, resulting in higher health-economic burden for the statutory healthcare system. © 2021 The Authors.
Erscheinungsjahr
2021
Zeitschriftentitel
Molecular genetics and metabolism reports
Band
27
Art.-Nr.
100764
eISSN
2214-4269
Page URI
https://pub.uni-bielefeld.de/record/2955233

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Trefz F, Muntau AC, Schneider KM, et al. Health economic burden of patients with phenylketonuria (PKU) - A retrospective study of German health insurance claims data. Molecular genetics and metabolism reports. 2021;27: 100764.
Trefz, F., Muntau, A. C., Schneider, K. M., Altevers, J., Jacob, C., Braun, S., Greiner, W., et al. (2021). Health economic burden of patients with phenylketonuria (PKU) - A retrospective study of German health insurance claims data. Molecular genetics and metabolism reports, 27, 100764. https://doi.org/10.1016/j.ymgmr.2021.100764
Trefz, F., Muntau, A. C., Schneider, K. M., Altevers, J., Jacob, C., Braun, S., Greiner, W., Jha, A., Jain, M., Alvarez, I., et al. (2021). Health economic burden of patients with phenylketonuria (PKU) - A retrospective study of German health insurance claims data. Molecular genetics and metabolism reports 27:100764.
Trefz, F., et al., 2021. Health economic burden of patients with phenylketonuria (PKU) - A retrospective study of German health insurance claims data. Molecular genetics and metabolism reports, 27: 100764.
F. Trefz, et al., “Health economic burden of patients with phenylketonuria (PKU) - A retrospective study of German health insurance claims data”, Molecular genetics and metabolism reports, vol. 27, 2021, : 100764.
Trefz, F., Muntau, A.C., Schneider, K.M., Altevers, J., Jacob, C., Braun, S., Greiner, W., Jha, A., Jain, M., Alvarez, I., Lane, P., Zeiss, C., Rutsch, F.: Health economic burden of patients with phenylketonuria (PKU) - A retrospective study of German health insurance claims data. Molecular genetics and metabolism reports. 27, : 100764 (2021).
Trefz, Friedrich, Muntau, Ania C, Schneider, Kim M, Altevers, Julia, Jacob, Christian, Braun, Sebastian, Greiner, Wolfgang, Jha, Ashok, Jain, Mohit, Alvarez, Ignacio, Lane, Paul, Zeiss, Claudia, and Rutsch, Frank. “Health economic burden of patients with phenylketonuria (PKU) - A retrospective study of German health insurance claims data”. Molecular genetics and metabolism reports 27 (2021): 100764.

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