Practical handling of allergic reactions to COVID-19 vaccines: Aposition paper from German and Austrian Allergy Societies AeDA, DGAKI, GPA and OGAI

Klimek L, Bergmann K-C, Brehler R, Pfutzner W, Zuberbier T, Hartmann K, Jakob T, Novak N, Ring J, Merk H, Hamelmann E, et al. (2021)
Allergo journal international 30(3): 79–95.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Klimek, Ludger; Bergmann, Karl-Christian; Brehler, Randolf; Pfutzner, Wolfgang; Zuberbier, Torsten; Hartmann, Karin; Jakob, Thilo; Novak, Natalija; Ring, Johannes; Merk, Hans; Hamelmann, EckardUniBi; Ankermann, Tobias
Alle
Abstract / Bemerkung
Background: For the preventive treatment of the 2019 coronavirus disease (COVID-19) an unprecedented global research effort studied the safety and efficacy of new vaccine platforms that have not been previously used in humans. Less than one year after the discovery of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral sequence, these vaccines were approved for use in the European Union (EU) as well as in numerous other countries and mass vaccination efforts began. The so far in the EU approved mRNA vaccines BNT162b2 and mRNA-1273 are based on similar lipid-based nanoparticle carrier technologies; however, the lipid components differ. Severe allergic reactions and anaphylaxis after COVID-19 vaccination are very rare adverse events but have drawn attention due to potentially lethal outcomes and have triggered ahigh degree of uncertainty.; Methods: Current knowledge on anaphylactic reactions to vaccines and specifically the new mRNA COVID-19 vaccines was compiled using aliterature search in Medline, PubMed, as well as the national and international study and guideline registries, the Cochrane Library, and the Internet, with special reference to official websites of the World Health Organization (WHO), US Centers for Disease Control and Prevention (CDC), Robert Koch Institute (RKI), and Paul Ehrlich Institute (PEI).; Results: Based on the international literature and previous experience, recommendations for prophylaxis, diagnosis and therapy of these allergic reactions are given by apanel of experts.; Conclusion: Allergy testing is not necessary for the vast majority of allergic patients prior to COVID-19 vaccination with currently licensed vaccines. In case of allergic/anaphylactic reactions after vaccination, allergy workup is recommended, as it is for asmall potential risk population prior to the first vaccination. Evaluation and approval of diagnostic tests should be done for this purpose. © The Author(s) 2021.
Erscheinungsjahr
2021
Zeitschriftentitel
Allergo journal international
Band
30
Ausgabe
3
Seite(n)
79–95
eISSN
2197-0378
Page URI
https://pub.uni-bielefeld.de/record/2954387

Zitieren

Klimek L, Bergmann K-C, Brehler R, et al. Practical handling of allergic reactions to COVID-19 vaccines: Aposition paper from German and Austrian Allergy Societies AeDA, DGAKI, GPA and OGAI. Allergo journal international. 2021;30(3):79–95.
Klimek, L., Bergmann, K. - C., Brehler, R., Pfutzner, W., Zuberbier, T., Hartmann, K., Jakob, T., et al. (2021). Practical handling of allergic reactions to COVID-19 vaccines: Aposition paper from German and Austrian Allergy Societies AeDA, DGAKI, GPA and OGAI. Allergo journal international, 30(3), 79–95. https://doi.org/10.1007/s40629-021-00165-7
Klimek, L., Bergmann, K. - C., Brehler, R., Pfutzner, W., Zuberbier, T., Hartmann, K., Jakob, T., Novak, N., Ring, J., Merk, H., et al. (2021). Practical handling of allergic reactions to COVID-19 vaccines: Aposition paper from German and Austrian Allergy Societies AeDA, DGAKI, GPA and OGAI. Allergo journal international 30, 79–95.
Klimek, L., et al., 2021. Practical handling of allergic reactions to COVID-19 vaccines: Aposition paper from German and Austrian Allergy Societies AeDA, DGAKI, GPA and OGAI. Allergo journal international, 30(3), p 79–95.
L. Klimek, et al., “Practical handling of allergic reactions to COVID-19 vaccines: Aposition paper from German and Austrian Allergy Societies AeDA, DGAKI, GPA and OGAI”, Allergo journal international, vol. 30, 2021, pp. 79–95.
Klimek, L., Bergmann, K.-C., Brehler, R., Pfutzner, W., Zuberbier, T., Hartmann, K., Jakob, T., Novak, N., Ring, J., Merk, H., Hamelmann, E., Ankermann, T., Schmidt, S., Untersmayr, E., Hotzenecker, W., Jensen-Jarolim, E., Brockow, K., Mahler, V., Worm, M.: Practical handling of allergic reactions to COVID-19 vaccines: Aposition paper from German and Austrian Allergy Societies AeDA, DGAKI, GPA and OGAI. Allergo journal international. 30, 79–95 (2021).
Klimek, Ludger, Bergmann, Karl-Christian, Brehler, Randolf, Pfutzner, Wolfgang, Zuberbier, Torsten, Hartmann, Karin, Jakob, Thilo, Novak, Natalija, Ring, Johannes, Merk, Hans, Hamelmann, Eckard, Ankermann, Tobias, Schmidt, Sebastian, Untersmayr, Eva, Hotzenecker, Wolfram, Jensen-Jarolim, Erika, Brockow, Knut, Mahler, Vera, and Worm, Margitta. “Practical handling of allergic reactions to COVID-19 vaccines: Aposition paper from German and Austrian Allergy Societies AeDA, DGAKI, GPA and OGAI”. Allergo journal international 30.3 (2021): 79–95.

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