In Vitro Assembly of Virus-Like Particles and Their Applications

Le DT, Müller K (2021)
Life 11(4): 334.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
Download
OA 559.97 KB
Autor*in
Le, Dinh To; Müller, KristianUniBi
Abstract / Bemerkung
Virus-like particles (VLPs) are increasingly used for vaccine development and drug delivery. Assembly of VLPs from purified monomers in a chemically defined reaction is advantageous compared to in vivo assembly, because it avoids encapsidation of host-derived components and enables loading with added cargoes. This review provides an overview of ex cella VLP production methods focusing on capsid protein production, factors that impact the in vitro assembly, and approaches to characterize in vitro VLPs. The uses of in vitro produced VLPs as vaccines and for therapeutic delivery are also reported.
Stichworte
capsid protein; in vitro assembly; virus-like particle; VLP-based vaccines; drug delivery
Erscheinungsjahr
2021
Zeitschriftentitel
Life
Band
11
Ausgabe
4
Art.-Nr.
334
eISSN
2075-1729
Finanzierungs-Informationen
Open-Access-Publikationskosten wurden durch die Universität Bielefeld gefördert.
Page URI
https://pub.uni-bielefeld.de/record/2954065

Zitieren

Le DT, Müller K. In Vitro Assembly of Virus-Like Particles and Their Applications. Life. 2021;11(4): 334.
Le, D. T., & Müller, K. (2021). In Vitro Assembly of Virus-Like Particles and Their Applications. Life, 11(4), 334. https://doi.org/10.3390/life11040334
Le, D. T., and Müller, K. (2021). In Vitro Assembly of Virus-Like Particles and Their Applications. Life 11:334.
Le, D.T., & Müller, K., 2021. In Vitro Assembly of Virus-Like Particles and Their Applications. Life, 11(4): 334.
D.T. Le and K. Müller, “In Vitro Assembly of Virus-Like Particles and Their Applications”, Life, vol. 11, 2021, : 334.
Le, D.T., Müller, K.: In Vitro Assembly of Virus-Like Particles and Their Applications. Life. 11, : 334 (2021).
Le, Dinh To, and Müller, Kristian. “In Vitro Assembly of Virus-Like Particles and Their Applications”. Life 11.4 (2021): 334.
Alle Dateien verfügbar unter der/den folgenden Lizenz(en):
Creative Commons Namensnennung 4.0 International Public License (CC-BY 4.0):
Volltext(e)
Access Level
OA Open Access
Zuletzt Hochgeladen
2021-04-19T11:40:47Z
MD5 Prüfsumme
fc3e4d3538745b951591aabcb9aca588

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 33920215
PubMed | Europe PMC

Suchen in

Google Scholar