In Vitro Assembly of Virus-Like Particles and Their Applications
Le DT, Müller K (2021)
Life 11(4): 334.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
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Le, Dinh To;
Müller, KristianUniBi 
Abstract / Bemerkung
Virus-like particles (VLPs) are increasingly used for vaccine development and drug delivery. Assembly of VLPs from purified monomers in a chemically defined reaction is advantageous compared to in vivo assembly, because it avoids encapsidation of host-derived components and enables loading with added cargoes. This review provides an overview of ex cella VLP production methods focusing on capsid protein production, factors that impact the in vitro assembly, and approaches to characterize in vitro VLPs. The uses of in vitro produced VLPs as vaccines and for therapeutic delivery are also reported.
Stichworte
capsid protein;
in vitro assembly;
virus-like particle;
VLP-based vaccines;
drug delivery
Erscheinungsjahr
2021
Zeitschriftentitel
Life
Band
11
Ausgabe
4
Art.-Nr.
334
Urheberrecht / Lizenzen
eISSN
2075-1729
Finanzierungs-Informationen
Open-Access-Publikationskosten wurden durch die Universität Bielefeld gefördert.
Page URI
https://pub.uni-bielefeld.de/record/2954065
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Le DT, Müller K. In Vitro Assembly of Virus-Like Particles and Their Applications. Life. 2021;11(4): 334.
Le, D. T., & Müller, K. (2021). In Vitro Assembly of Virus-Like Particles and Their Applications. Life, 11(4), 334. https://doi.org/10.3390/life11040334
Le, Dinh To, and Müller, Kristian. 2021. “In Vitro Assembly of Virus-Like Particles and Their Applications”. Life 11 (4): 334.
Le, D. T., and Müller, K. (2021). In Vitro Assembly of Virus-Like Particles and Their Applications. Life 11:334.
Le, D.T., & Müller, K., 2021. In Vitro Assembly of Virus-Like Particles and Their Applications. Life, 11(4): 334.
D.T. Le and K. Müller, “In Vitro Assembly of Virus-Like Particles and Their Applications”, Life, vol. 11, 2021, : 334.
Le, D.T., Müller, K.: In Vitro Assembly of Virus-Like Particles and Their Applications. Life. 11, : 334 (2021).
Le, Dinh To, and Müller, Kristian. “In Vitro Assembly of Virus-Like Particles and Their Applications”. Life 11.4 (2021): 334.
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2021-04-19T11:40:47Z
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fc3e4d3538745b951591aabcb9aca588
Daten bereitgestellt von European Bioinformatics Institute (EBI)
Zitationen in Europe PMC
Daten bereitgestellt von Europe PubMed Central.
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Daten bereitgestellt von Europe PubMed Central.
Material in PUB:
Teil dieser Dissertation
Analysis, Optimization and Application of AAV Capsid Assembly using Escherichia coli
Le DT (2021)
Bielefeld: Universität Bielefeld.
Le DT (2021)
Bielefeld: Universität Bielefeld.
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