Abstract / Bemerkung
Background A value set for the EuroQoL 5-Dimensions (EQ-5D)-Y in Slovenia is not yet available, making the calculation of quality-adjusted life-years (QALYs) for children and adolescents using this generic instrument impossible. Objective The main objective of our study was to obtain adult preferences towards EQ-5D-Y health states in Slovenia, following the EQ-5D-Y-3L international valuation protocol. The adults were asked to take the perspective of a hypothetical 10-year-old child. Method A sample of 1074 adults in Slovenia completed an online discrete-choice experiment (DCE) survey on EQ-5D-Y health states. The latent scale issue was addressed by obtaining the value of the anchor (33333) with 200 composite time trade-off (cTTO) interviews. A mixed (random coefficients) logit model was used to estimate the value set. Results All the estimated coefficients of the mixed logit model were statistically significant at the 1% level and had an expected negative sign. The most important health dimension in EQ-5D-Y is pain/discomfort, followed by anxiety/depression, usual activities, and mobility, with self-care being the least important health dimension. Conclusions The study addresses an important research gap and presents the EQ-5D-Y value set for Slovenia. At the time of writing, no published value sets are available for the EQ-5D-Y-3L appropriate for use in QALY calculations, making this value set the first EQ-5D-Y value set in the world.
Prevolnik Rupel V, Ogorevc M, Greiner W, Kreimeier S, Ludwig K, Ramos-Goni JM. EQ-5D-Y Value Set for Slovenia. PharmacoEconomics. 2021.
Prevolnik Rupel, V., Ogorevc, M., Greiner, W., Kreimeier, S., Ludwig, K., & Ramos-Goni, J. M. (2021). EQ-5D-Y Value Set for Slovenia. PharmacoEconomics. https://doi.org/10.1007/s40273-020-00994-4
Prevolnik Rupel, V., Ogorevc, M., Greiner, W., Kreimeier, S., Ludwig, K., and Ramos-Goni, J. M. (2021). EQ-5D-Y Value Set for Slovenia. PharmacoEconomics.
Prevolnik Rupel, V., et al., 2021. EQ-5D-Y Value Set for Slovenia. PharmacoEconomics.
V. Prevolnik Rupel, et al., “EQ-5D-Y Value Set for Slovenia”, PharmacoEconomics, 2021.
Prevolnik Rupel, V., Ogorevc, M., Greiner, W., Kreimeier, S., Ludwig, K., Ramos-Goni, J.M.: EQ-5D-Y Value Set for Slovenia. PharmacoEconomics. (2021).
Prevolnik Rupel, Valentina, Ogorevc, Marko, Greiner, Wolfgang, Kreimeier, Simone, Ludwig, Kristina, and Ramos-Goni, Juan Manuel. “EQ-5D-Y Value Set for Slovenia”. PharmacoEconomics (2021).