Chemical constituents from Ficus natalensis hochst (Moraceae) and their chemophenetic significance

Mbougnia JFT, Happi GM, Bitchagno Mbahbou GT, Awouafack MD, Lenta BN, Kouam SF, Tane P, Sewald N, Tene M (2021)
Biochemical Systematics and Ecology 95: 104227.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Mbougnia, Judith F.T.; Happi, Gervais M.; Bitchagno Mbahbou, Gabin ThierryUniBi; Awouafack, Maurice D.; Lenta, Bruno N.; Kouam, Simeon F.; Tane, Pierre; Sewald, NorbertUniBi ; Tene, Mathieu
Abstract / Bemerkung
Phytochemical investigation of the stem bark of Ficus natalensis afforded eleven compounds including one ceramide (1), two anthraquinones (2, 3), four triterpenes (4–7), two polyols (8, 9) and two steroids (10, 11). The structures of the compounds were determined by spectroscopic analyses including IR, UV, MS, 1D- and 2D- NMR (1H, 13C, 1H–1H COSY, HMQC, HMBC and NOESY), as well as by comparison with literature data. The antibacterial activity and the cytotoxicity of the extract, fractions and some isolated compounds (3, 5, 8 and 9) were evaluated. Some fractions and sub-fractions from various column chromatography displayed moderate antibacterial activity with diameter zone of inhibition (DZI) ranging from 7 to 10 mm. None of the compounds tested had activity. In the present study, all the compounds are isolated for the first time from the species F. natalensis. Compounds 2, 4–7, 10 and 11 were previously reported from the genus Ficus. The chemophenetic significance of the isolated compounds is discussed.
Erscheinungsjahr
2021
Zeitschriftentitel
Biochemical Systematics and Ecology
Band
95
Art.-Nr.
104227
ISSN
03051978
Page URI
https://pub.uni-bielefeld.de/record/2950331

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Mbougnia JFT, Happi GM, Bitchagno Mbahbou GT, et al. Chemical constituents from Ficus natalensis hochst (Moraceae) and their chemophenetic significance. Biochemical Systematics and Ecology. 2021;95: 104227.
Mbougnia, J. F. T., Happi, G. M., Bitchagno Mbahbou, G. T., Awouafack, M. D., Lenta, B. N., Kouam, S. F., Tane, P., et al. (2021). Chemical constituents from Ficus natalensis hochst (Moraceae) and their chemophenetic significance. Biochemical Systematics and Ecology, 95, 104227. doi:10.1016/j.bse.2021.104227
Mbougnia, J. F. T., Happi, G. M., Bitchagno Mbahbou, G. T., Awouafack, M. D., Lenta, B. N., Kouam, S. F., Tane, P., Sewald, N., and Tene, M. (2021). Chemical constituents from Ficus natalensis hochst (Moraceae) and their chemophenetic significance. Biochemical Systematics and Ecology 95:104227.
Mbougnia, J.F.T., et al., 2021. Chemical constituents from Ficus natalensis hochst (Moraceae) and their chemophenetic significance. Biochemical Systematics and Ecology, 95: 104227.
J.F.T. Mbougnia, et al., “Chemical constituents from Ficus natalensis hochst (Moraceae) and their chemophenetic significance”, Biochemical Systematics and Ecology, vol. 95, 2021, : 104227.
Mbougnia, J.F.T., Happi, G.M., Bitchagno Mbahbou, G.T., Awouafack, M.D., Lenta, B.N., Kouam, S.F., Tane, P., Sewald, N., Tene, M.: Chemical constituents from Ficus natalensis hochst (Moraceae) and their chemophenetic significance. Biochemical Systematics and Ecology. 95, : 104227 (2021).
Mbougnia, Judith F.T., Happi, Gervais M., Bitchagno Mbahbou, Gabin Thierry, Awouafack, Maurice D., Lenta, Bruno N., Kouam, Simeon F., Tane, Pierre, Sewald, Norbert, and Tene, Mathieu. “Chemical constituents from Ficus natalensis hochst (Moraceae) and their chemophenetic significance”. Biochemical Systematics and Ecology 95 (2021): 104227.

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