Photonic Technologies for Liquid Biopsies: Recent Advances and Open Research Challenges

Dell'Olio F, Su J, Huser T, Sottile V, Cortes-Hernandez LE, Alix-Panabieres C (2020)
Laser & Photonics Reviews 15(1): 2000255.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
Download
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Autor*in
Dell'Olio, Francesco; Su, Judith; Huser, ThomasUniBi ; Sottile, Virginie; Cortes-Hernandez, Luis Enrique; Alix-Panabieres, Catherine
Abstract / Bemerkung
The recent development of sophisticated techniques capable of detecting extremely low concentrations of circulating tumor biomarkers in accessible body fluids, such as blood or urine, could contribute to a paradigm shift in cancer diagnosis and treatment. By applying such techniques, clinicians can carry out liquid biopsies, providing information on tumor presence, evolution, and response to therapy. The implementation of biosensing platforms for liquid biopsies is particularly complex because this application domain demands high selectivity/specificity and challenging limit-of-detection (LoD) values. The interest in photonics as an enabling technology for liquid biopsies is growing owing to the well-known advantages of photonic biosensors over competing technologies in terms of compactness, immunity to external disturbance, and ultrahigh spatial resolution. Some encouraging experimental results in the field of photonic devices and systems for liquid biopsy have already been achieved by using fluorescent labels and label-free techniques and by exploiting super-resolution microscopy, surface plasmon resonance, surface-enhanced Raman scattering, and whispering gallery mode resonators. The current state-of-the-art is critically reviewed here, starting from the requirements imposed by the detection of the most common circulating biomarkers. Open research challenges are considered together with competing technologies, and the most promising paths of improvement are discussed for future applications.
Stichworte
liquid biopsies; oncologyoptical microscopy; plasmonics; whispering; gallery modes
Erscheinungsjahr
2020
Zeitschriftentitel
Laser & Photonics Reviews
Band
15
Ausgabe
1
Art.-Nr.
2000255
ISSN
1863-8880
eISSN
1863-8899
Page URI
https://pub.uni-bielefeld.de/record/2950219

Zitieren

Dell'Olio F, Su J, Huser T, Sottile V, Cortes-Hernandez LE, Alix-Panabieres C. Photonic Technologies for Liquid Biopsies: Recent Advances and Open Research Challenges. Laser & Photonics Reviews. 2020;15(1): 2000255.
Dell'Olio, F., Su, J., Huser, T., Sottile, V., Cortes-Hernandez, L. E., & Alix-Panabieres, C. (2020). Photonic Technologies for Liquid Biopsies: Recent Advances and Open Research Challenges. Laser & Photonics Reviews, 15(1), 2000255. doi:10.1002/lpor.202000255
Dell'Olio, F., Su, J., Huser, T., Sottile, V., Cortes-Hernandez, L. E., and Alix-Panabieres, C. (2020). Photonic Technologies for Liquid Biopsies: Recent Advances and Open Research Challenges. Laser & Photonics Reviews 15:2000255.
Dell'Olio, F., et al., 2020. Photonic Technologies for Liquid Biopsies: Recent Advances and Open Research Challenges. Laser & Photonics Reviews, 15(1): 2000255.
F. Dell'Olio, et al., “Photonic Technologies for Liquid Biopsies: Recent Advances and Open Research Challenges”, Laser & Photonics Reviews, vol. 15, 2020, : 2000255.
Dell'Olio, F., Su, J., Huser, T., Sottile, V., Cortes-Hernandez, L.E., Alix-Panabieres, C.: Photonic Technologies for Liquid Biopsies: Recent Advances and Open Research Challenges. Laser & Photonics Reviews. 15, : 2000255 (2020).
Dell'Olio, Francesco, Su, Judith, Huser, Thomas, Sottile, Virginie, Cortes-Hernandez, Luis Enrique, and Alix-Panabieres, Catherine. “Photonic Technologies for Liquid Biopsies: Recent Advances and Open Research Challenges”. Laser & Photonics Reviews 15.1 (2020): 2000255.

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Suchen in

Google Scholar