New anthraquinone derivatives from the stem barks of Morinda lucida Benth

Ekon JPL, Zra T, Songue JL, Ngoko MLW, Ngassoum MB, Talla E, Waffo AFK, Sewald N, Wansi JD (2020)
Phytochemistry Letters 39: 94-98.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Ekon, Jean Pierre Longue; Zra, Tize; Songue, Jules Lobe; Ngoko, Mireille Laura Wondja; Ngassoum, Martin Benoit; Talla, Emmanuel; Waffo, Alain Francois Kamdem; Sewald, NorbertUniBi ; Wansi, Jean Duplex
Abstract / Bemerkung
Three new anthraquinone derivatives including (2S, 3R)-1,2,3,4-tetrahydro-2,3,6-trihydroxy-2-methylan-thracene-9,10-dione (1), 3,6-dihydroxy-1,2-dimethoxyanthraquinone (2) and 1,6-dihydroxy-2-hydroxymethyl5-methoxyanthraquinone (3) together with thirteen known compounds including eleven anthraquinones and two triterpenes were isolated from the methanolic crude extract of the stem barks of Morinda lucida. The structures of the new compounds were unambiguously elucidated on the basis of modern NMR spectroscopic methods, as well as by high-resolution mass spectrometry. The known compounds were identified on the basis of their spectral characteristics and by comparison with literature data. The antimicrobial activities of (2S, 3R)1,2,3,4-tetrahydro-2,3,6-trihydroxy-2-methylanthracene-9,10-dione (1), the methanolic crude extract and its fractions were evaluated against five bacteria and four fungi. The lowest values of the MIC (256 mu g/mL) were recorded on Candida parapsilosis, Cryptococcus neoformans for the methanolic crude extract and on Salmonella typhi for the ethyl acetate fraction.
Stichworte
Rubiaceae; Morinda lucida; Anthraquinone; Antimicrobial activities
Erscheinungsjahr
2020
Zeitschriftentitel
Phytochemistry Letters
Band
39
Seite(n)
94-98
ISSN
1874-3900
eISSN
1876-7486
Page URI
https://pub.uni-bielefeld.de/record/2949709

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Ekon JPL, Zra T, Songue JL, et al. New anthraquinone derivatives from the stem barks of Morinda lucida Benth. Phytochemistry Letters. 2020;39:94-98.
Ekon, J. P. L., Zra, T., Songue, J. L., Ngoko, M. L. W., Ngassoum, M. B., Talla, E., Waffo, A. F. K., et al. (2020). New anthraquinone derivatives from the stem barks of Morinda lucida Benth. Phytochemistry Letters, 39, 94-98. doi:10.1016/j.phytol.2020.06.010
Ekon, J. P. L., Zra, T., Songue, J. L., Ngoko, M. L. W., Ngassoum, M. B., Talla, E., Waffo, A. F. K., Sewald, N., and Wansi, J. D. (2020). New anthraquinone derivatives from the stem barks of Morinda lucida Benth. Phytochemistry Letters 39, 94-98.
Ekon, J.P.L., et al., 2020. New anthraquinone derivatives from the stem barks of Morinda lucida Benth. Phytochemistry Letters, 39, p 94-98.
J.P.L. Ekon, et al., “New anthraquinone derivatives from the stem barks of Morinda lucida Benth”, Phytochemistry Letters, vol. 39, 2020, pp. 94-98.
Ekon, J.P.L., Zra, T., Songue, J.L., Ngoko, M.L.W., Ngassoum, M.B., Talla, E., Waffo, A.F.K., Sewald, N., Wansi, J.D.: New anthraquinone derivatives from the stem barks of Morinda lucida Benth. Phytochemistry Letters. 39, 94-98 (2020).
Ekon, Jean Pierre Longue, Zra, Tize, Songue, Jules Lobe, Ngoko, Mireille Laura Wondja, Ngassoum, Martin Benoit, Talla, Emmanuel, Waffo, Alain Francois Kamdem, Sewald, Norbert, and Wansi, Jean Duplex. “New anthraquinone derivatives from the stem barks of Morinda lucida Benth”. Phytochemistry Letters 39 (2020): 94-98.

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