Heptacyclosordarianone, a New Polyketide From Sordaria sp., an Endophytic Fungus From Garcinia polyantha

Tankeu VFT, Sema DK, Jouda J-B, Tatsimo SJN, Ntonga PA, Wansi JD, Fogue SK, Loura B, Shiono Y, Sewald N, Lannang AM (2020)
Natural Product Communications 15(11): 1934578X20977622.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Tankeu, Virginie Flaure Tsague; Sema, Denis Kehdinga; Jouda, Jean-Bosco; Tatsimo, Simplice Joel N.; Ntonga, Patrick Akono; Wansi, Jean Duplex; Fogue, Simeon Kouam; Loura, Benoit; Shiono, Yoshihito; Sewald, NorbertUniBi ; Lannang, Alain Meli
Abstract / Bemerkung
One new polyketide derivative, heptacyclosordarianone (1), together with 2 known compounds, heptacyclosordariolone (2) and sordariol (3), were isolated from an extract of Sordaria sp. AM-71, an endophytic fungus inhabiting Garcinia polyantha. The structures of these compounds were elucidated based on intensive nuclear magnetic resonance spectroscopy and high-resolution mass spectrometry and by comparison with literature data. All compounds were assayed for their antimicrobial and cytotoxic properties. Only compound 2 showed antimicrobial activities against Bacillus subtilis DSMZ 704, Pseudomonas agarici DSMZ 11810, and Micrococcus luteus DSMZ 1605 with minimum inhibitory concentration values of 9.3, 15.5, and 16.9 mu g/mL respectively. None of the isolated compounds showed a significant cytotoxic property.
Stichworte
Garcinia; Sordaria sp; polyketide; antimicrobial activity
Erscheinungsjahr
2020
Zeitschriftentitel
Natural Product Communications
Band
15
Ausgabe
11
Art.-Nr.
1934578X20977622
ISSN
1934-578X
eISSN
1555-9475
Page URI
https://pub.uni-bielefeld.de/record/2949707

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Tankeu VFT, Sema DK, Jouda J-B, et al. Heptacyclosordarianone, a New Polyketide From Sordaria sp., an Endophytic Fungus From Garcinia polyantha. Natural Product Communications. 2020;15(11): 1934578X20977622.
Tankeu, V. F. T., Sema, D. K., Jouda, J. - B., Tatsimo, S. J. N., Ntonga, P. A., Wansi, J. D., Fogue, S. K., et al. (2020). Heptacyclosordarianone, a New Polyketide From Sordaria sp., an Endophytic Fungus From Garcinia polyantha. Natural Product Communications, 15(11), 1934578X20977622. doi:10.1177/1934578X20977622
Tankeu, V. F. T., Sema, D. K., Jouda, J. - B., Tatsimo, S. J. N., Ntonga, P. A., Wansi, J. D., Fogue, S. K., Loura, B., Shiono, Y., Sewald, N., et al. (2020). Heptacyclosordarianone, a New Polyketide From Sordaria sp., an Endophytic Fungus From Garcinia polyantha. Natural Product Communications 15:1934578X20977622.
Tankeu, V.F.T., et al., 2020. Heptacyclosordarianone, a New Polyketide From Sordaria sp., an Endophytic Fungus From Garcinia polyantha. Natural Product Communications, 15(11): 1934578X20977622.
V.F.T. Tankeu, et al., “Heptacyclosordarianone, a New Polyketide From Sordaria sp., an Endophytic Fungus From Garcinia polyantha”, Natural Product Communications, vol. 15, 2020, : 1934578X20977622.
Tankeu, V.F.T., Sema, D.K., Jouda, J.-B., Tatsimo, S.J.N., Ntonga, P.A., Wansi, J.D., Fogue, S.K., Loura, B., Shiono, Y., Sewald, N., Lannang, A.M.: Heptacyclosordarianone, a New Polyketide From Sordaria sp., an Endophytic Fungus From Garcinia polyantha. Natural Product Communications. 15, : 1934578X20977622 (2020).
Tankeu, Virginie Flaure Tsague, Sema, Denis Kehdinga, Jouda, Jean-Bosco, Tatsimo, Simplice Joel N., Ntonga, Patrick Akono, Wansi, Jean Duplex, Fogue, Simeon Kouam, Loura, Benoit, Shiono, Yoshihito, Sewald, Norbert, and Lannang, Alain Meli. “Heptacyclosordarianone, a New Polyketide From Sordaria sp., an Endophytic Fungus From Garcinia polyantha”. Natural Product Communications 15.11 (2020): 1934578X20977622.

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