An Antibacterial Isovaleronitrile Diglycoside From Detarium microcarpum Guill. Perr. (Fabaceae)

Feudjou WF, Mbock AM, Ouahouo MBW, Sielinou VT, Gounoue RK, Mkounga P, Lenta BN, Dimo T, Fekam FB, Sewald N, Nkengfack AE (2020)
NATURAL PRODUCT COMMUNICATIONS 15(7): UNSP 1934578X20936939.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Feudjou, William F.; Mbock, Arnaud M.; Ouahouo, Marlyse B. W.; Sielinou, Valerie T.; Gounoue, Raceline K.; Mkounga, Pierre; Lenta, Bruno N.; Dimo, Theophile; Fekam, Fabrice B.; Sewald, NorbertUniBi ; Nkengfack, Augustin E.
Abstract / Bemerkung
A new isovaleronitrile diglycoside, named microcarposide (1), together with 6 known compounds: lupeol (2), betulinic acid (3), beta-sitosterol glucoside (4), methyl gallate (5), luteolin (6), and epicatechin (7), was isolated from the methanolic extract of the fruits of Detarium microcarpum Guill. Perr. The structures of the compounds were determined by extensive analysis of 1D- and 2D-H-1 and C-13 NMR spectroscopic data in conjunction with mass spectrometry and by comparison with data reported in the literature. Compound 1 was characterized as (2R)-2-[(6 ''-O-beta-L-rhamnopyranosyl-beta-D-glucopyranosyl)oxy]-3-methylbutanenitrile. Some of the isolated compounds were evaluated for their antibacterial activities against several microorganisms; only compound 1 was active against Salmonella typhi, Salmonella enteritidis, and Salmonella typhimurium with minimum inhibition concentration values of 153.4, 76.7, and 76.7 mu M, respectively.
Stichworte
Fabaceae; Detarium microcarpum; isovaleronitrile diglycoside; microcarposide; antibacterial activity
Erscheinungsjahr
2020
Zeitschriftentitel
NATURAL PRODUCT COMMUNICATIONS
Band
15
Ausgabe
7
Art.-Nr.
UNSP 1934578X20936939
ISSN
1934-578X
eISSN
1555-9475
Page URI
https://pub.uni-bielefeld.de/record/2945123

Zitieren

Feudjou WF, Mbock AM, Ouahouo MBW, et al. An Antibacterial Isovaleronitrile Diglycoside From Detarium microcarpum Guill. Perr. (Fabaceae). NATURAL PRODUCT COMMUNICATIONS. 2020;15(7): UNSP 1934578X20936939.
Feudjou, W. F., Mbock, A. M., Ouahouo, M. B. W., Sielinou, V. T., Gounoue, R. K., Mkounga, P., Lenta, B. N., et al. (2020). An Antibacterial Isovaleronitrile Diglycoside From Detarium microcarpum Guill. Perr. (Fabaceae). NATURAL PRODUCT COMMUNICATIONS, 15(7), UNSP 1934578X20936939. doi:10.1177/1934578X20936939
Feudjou, W. F., Mbock, A. M., Ouahouo, M. B. W., Sielinou, V. T., Gounoue, R. K., Mkounga, P., Lenta, B. N., Dimo, T., Fekam, F. B., Sewald, N., et al. (2020). An Antibacterial Isovaleronitrile Diglycoside From Detarium microcarpum Guill. Perr. (Fabaceae). NATURAL PRODUCT COMMUNICATIONS 15:UNSP 1934578X20936939.
Feudjou, W.F., et al., 2020. An Antibacterial Isovaleronitrile Diglycoside From Detarium microcarpum Guill. Perr. (Fabaceae). NATURAL PRODUCT COMMUNICATIONS, 15(7): UNSP 1934578X20936939.
W.F. Feudjou, et al., “An Antibacterial Isovaleronitrile Diglycoside From Detarium microcarpum Guill. Perr. (Fabaceae)”, NATURAL PRODUCT COMMUNICATIONS, vol. 15, 2020, : UNSP 1934578X20936939.
Feudjou, W.F., Mbock, A.M., Ouahouo, M.B.W., Sielinou, V.T., Gounoue, R.K., Mkounga, P., Lenta, B.N., Dimo, T., Fekam, F.B., Sewald, N., Nkengfack, A.E.: An Antibacterial Isovaleronitrile Diglycoside From Detarium microcarpum Guill. Perr. (Fabaceae). NATURAL PRODUCT COMMUNICATIONS. 15, : UNSP 1934578X20936939 (2020).
Feudjou, William F., Mbock, Arnaud M., Ouahouo, Marlyse B. W., Sielinou, Valerie T., Gounoue, Raceline K., Mkounga, Pierre, Lenta, Bruno N., Dimo, Theophile, Fekam, Fabrice B., Sewald, Norbert, and Nkengfack, Augustin E. “An Antibacterial Isovaleronitrile Diglycoside From Detarium microcarpum Guill. Perr. (Fabaceae)”. NATURAL PRODUCT COMMUNICATIONS 15.7 (2020): UNSP 1934578X20936939.

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