(R)-α-Aminoadipic Acid: A Versatile Precursor for the Synthesis of D-Amino Acids

Sadiq A, Sewald N (2013)
Journal of Amino Acids 2013: 252813.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Abstract / Bemerkung
The ready accessibility of (R)-α-aminoadipic acid by enzymatic cleavage of cephalosporin C (CephC) in the production of 7-aminocephalosporanic acid (7-ACA) on a large scale makes it a favorable chiral pool building block for the synthesis of unusual amino acids. A route for the synthesis of C-5-alkenyl and C-6-alkylidene derivatives of (R)-pipecolic acid is described which utilizes (R)-α-aminoadipic acid as the enantiomerically pure starting material. Moreover, the synthesis of azido and triazolyl derivatives of (R)-α-aminoadipic acid is reported.
Erscheinungsjahr
2013
Zeitschriftentitel
Journal of Amino Acids
Band
2013
Art.-Nr.
252813
ISSN
2090-0104
eISSN
2090-0112
Page URI
https://pub.uni-bielefeld.de/record/2944904

Zitieren

Sadiq A, Sewald N. (R)-α-Aminoadipic Acid: A Versatile Precursor for the Synthesis of D-Amino Acids. Journal of Amino Acids. 2013;2013: 252813.
Sadiq, A., & Sewald, N. (2013). (R)-α-Aminoadipic Acid: A Versatile Precursor for the Synthesis of D-Amino Acids. Journal of Amino Acids, 2013, 252813. doi:10.1155/2013/252813
Sadiq, Amina, and Sewald, Norbert. 2013. “(R)-α-Aminoadipic Acid: A Versatile Precursor for the Synthesis of D-Amino Acids”. Journal of Amino Acids 2013: 252813.
Sadiq, A., and Sewald, N. (2013). (R)-α-Aminoadipic Acid: A Versatile Precursor for the Synthesis of D-Amino Acids. Journal of Amino Acids 2013:252813.
Sadiq, A., & Sewald, N., 2013. (R)-α-Aminoadipic Acid: A Versatile Precursor for the Synthesis of D-Amino Acids. Journal of Amino Acids, 2013: 252813.
A. Sadiq and N. Sewald, “(R)-α-Aminoadipic Acid: A Versatile Precursor for the Synthesis of D-Amino Acids”, Journal of Amino Acids, vol. 2013, 2013, : 252813.
Sadiq, A., Sewald, N.: (R)-α-Aminoadipic Acid: A Versatile Precursor for the Synthesis of D-Amino Acids. Journal of Amino Acids. 2013, : 252813 (2013).
Sadiq, Amina, and Sewald, Norbert. “(R)-α-Aminoadipic Acid: A Versatile Precursor for the Synthesis of D-Amino Acids”. Journal of Amino Acids 2013 (2013): 252813.
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