Chemical constituents from the bark of the Cameroonian mahogany Trichilia emetica Vahl (Meliaceae)
Tsopgni WDT, Happi GM, Stammler H-G, Neumann B, Mbobda ASW, Kouam SF, Frese M, Azebaze AGB, Lenta BN, Sewald N (2019)
Phytochemistry Letters 33: 49-54.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
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Autor*in
Tsopgni, Willifred Dongmo T.;
Happi, Gervais Mouthee;
Stammler, Hans-GeorgUniBi;
Neumann, BeateUniBi;
Mbobda, Alexis Sylvain W.;
Kouam, Simeon Fogue;
Frese, MarcelUniBi ;
Azebaze, Anatole Guy B.;
Lenta, Bruno N.;
Sewald, NorbertUniBi
Einrichtung
Abstract / Bemerkung
Phytochemical investigation of the stem bark extract of Trichilia emetica led to the isolation of two new naturally occurring compounds including a prieurianin-class limonoid named trichirokin (1) and the steroid ergosta-5,24(28)-diene-3S, 16S, 20S-triol (4), along with nine known compounds characterized as rohituka-3 (3), rohituka-9 (2), scopoletin, benzoic acid, protocatechuic acid, lignoceric acid, beta-sitosterol, stigmasterol and beta-sitosterol-3-O-beta-D-glucopyranoside. The crystal structures of rohituka-3 (3) and ergosta-5,24(28)-diene-3S, 16S, 20S-triol (4) are reported here for the first time. The structures of the compounds were elucidated by extensive spectroscopic and spectrometric data interpretation. The stereochemistry of compound 1 was established on the basis of its NOESY spectrum and the comparison of its optical rotation value with that of its congener 2. None of the reported compounds displayed antibacterial or cytotoxic activity.
Stichworte
Trichilia emetica;
Meliaceae;
Limonoid;
Steroid;
X-ray structure
Erscheinungsjahr
2019
Zeitschriftentitel
Phytochemistry Letters
Band
33
Seite(n)
49-54
ISSN
1874-3900
eISSN
1876-7486
Page URI
https://pub.uni-bielefeld.de/record/2938384
Zitieren
Tsopgni WDT, Happi GM, Stammler H-G, et al. Chemical constituents from the bark of the Cameroonian mahogany Trichilia emetica Vahl (Meliaceae). Phytochemistry Letters. 2019;33:49-54.
Tsopgni, W. D. T., Happi, G. M., Stammler, H. - G., Neumann, B., Mbobda, A. S. W., Kouam, S. F., Frese, M., et al. (2019). Chemical constituents from the bark of the Cameroonian mahogany Trichilia emetica Vahl (Meliaceae). Phytochemistry Letters, 33, 49-54. doi:10.1016/j.phytol.2019.07.009
Tsopgni, Willifred Dongmo T., Happi, Gervais Mouthee, Stammler, Hans-Georg, Neumann, Beate, Mbobda, Alexis Sylvain W., Kouam, Simeon Fogue, Frese, Marcel, Azebaze, Anatole Guy B., Lenta, Bruno N., and Sewald, Norbert. 2019. “Chemical constituents from the bark of the Cameroonian mahogany Trichilia emetica Vahl (Meliaceae)”. Phytochemistry Letters 33: 49-54.
Tsopgni, W. D. T., Happi, G. M., Stammler, H. - G., Neumann, B., Mbobda, A. S. W., Kouam, S. F., Frese, M., Azebaze, A. G. B., Lenta, B. N., and Sewald, N. (2019). Chemical constituents from the bark of the Cameroonian mahogany Trichilia emetica Vahl (Meliaceae). Phytochemistry Letters 33, 49-54.
Tsopgni, W.D.T., et al., 2019. Chemical constituents from the bark of the Cameroonian mahogany Trichilia emetica Vahl (Meliaceae). Phytochemistry Letters, 33, p 49-54.
W.D.T. Tsopgni, et al., “Chemical constituents from the bark of the Cameroonian mahogany Trichilia emetica Vahl (Meliaceae)”, Phytochemistry Letters, vol. 33, 2019, pp. 49-54.
Tsopgni, W.D.T., Happi, G.M., Stammler, H.-G., Neumann, B., Mbobda, A.S.W., Kouam, S.F., Frese, M., Azebaze, A.G.B., Lenta, B.N., Sewald, N.: Chemical constituents from the bark of the Cameroonian mahogany Trichilia emetica Vahl (Meliaceae). Phytochemistry Letters. 33, 49-54 (2019).
Tsopgni, Willifred Dongmo T., Happi, Gervais Mouthee, Stammler, Hans-Georg, Neumann, Beate, Mbobda, Alexis Sylvain W., Kouam, Simeon Fogue, Frese, Marcel, Azebaze, Anatole Guy B., Lenta, Bruno N., and Sewald, Norbert. “Chemical constituents from the bark of the Cameroonian mahogany Trichilia emetica Vahl (Meliaceae)”. Phytochemistry Letters 33 (2019): 49-54.
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