Coumamarin: a first coumarinyl calcium complex isolated from nature.
Hamed A, Abdel-Razek AS, Frese M, Sproß J, Stammler H-G, Sewald N, Shaaban M (2019)
Journal of antibiotics 72(10): 729-735.
Zeitschriftenaufsatz
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Autor*in
Hamed, Abdelaaty;
Abdel-Razek, Ahmed S;
Frese, MarcelUniBi 
;
Sproß, JensUniBi;
Stammler, Hans-GeorgUniBi;
Sewald, NorbertUniBi ;
Shaaban, Mohamed
;
Sproß, JensUniBi;
Stammler, Hans-GeorgUniBi;
Sewald, NorbertUniBi ;
Shaaban, MohamedEinrichtung
Abstract / Bemerkung
The first calcium complex from nature, Coumamarin (1), 7-hydroxy-3-methoxy-2-oxo-2H-chromene-6-carboxylate Ca(II) complex, was isolated from Aspergillus sydowii ASTI, together with diorcinol (2), violaceol I (3), hydroxysydonic acid (4), cyclo (Trp-Phe), kojic acid, ergosterol, and uracil. The producing strain was isolated from marine water sample collected from Tiran Island, Red Sea, Egypt. Structure 1 was assigned by intensive 1D, 2D NMR, HR-ESIMS, and X-ray crystallography as well. Coumamarin is potentially active against certain tested bacteria and yeasts, while showing no cytotoxic activity against human cervix carcinoma cell line (KB-3-1). Taxonomically, the fungus was identified by phylogenetic analysis of its 18S rRNA gene sequence.
Erscheinungsjahr
2019
Zeitschriftentitel
Journal of antibiotics
Band
72
Ausgabe
10
Seite(n)
729-735
ISSN
0021-8820
Page URI
https://pub.uni-bielefeld.de/record/2936484
Zitieren
Hamed A, Abdel-Razek AS, Frese M, et al. Coumamarin: a first coumarinyl calcium complex isolated from nature. Journal of antibiotics. 2019;72(10):729-735.
Hamed, A., Abdel-Razek, A. S., Frese, M., Sproß, J., Stammler, H. - G., Sewald, N., & Shaaban, M. (2019). Coumamarin: a first coumarinyl calcium complex isolated from nature. Journal of antibiotics, 72(10), 729-735. doi:10.1038/s41429-019-0207-7
Hamed, Abdelaaty, Abdel-Razek, Ahmed S, Frese, Marcel, Sproß, Jens, Stammler, Hans-Georg, Sewald, Norbert, and Shaaban, Mohamed. 2019. “Coumamarin: a first coumarinyl calcium complex isolated from nature.”. Journal of antibiotics 72 (10): 729-735.
Hamed, A., Abdel-Razek, A. S., Frese, M., Sproß, J., Stammler, H. - G., Sewald, N., and Shaaban, M. (2019). Coumamarin: a first coumarinyl calcium complex isolated from nature. Journal of antibiotics 72, 729-735.
Hamed, A., et al., 2019. Coumamarin: a first coumarinyl calcium complex isolated from nature. Journal of antibiotics, 72(10), p 729-735.
A. Hamed, et al., “Coumamarin: a first coumarinyl calcium complex isolated from nature.”, Journal of antibiotics, vol. 72, 2019, pp. 729-735.
Hamed, A., Abdel-Razek, A.S., Frese, M., Sproß, J., Stammler, H.-G., Sewald, N., Shaaban, M.: Coumamarin: a first coumarinyl calcium complex isolated from nature. Journal of antibiotics. 72, 729-735 (2019).
Hamed, Abdelaaty, Abdel-Razek, Ahmed S, Frese, Marcel, Sproß, Jens, Stammler, Hans-Georg, Sewald, Norbert, and Shaaban, Mohamed. “Coumamarin: a first coumarinyl calcium complex isolated from nature.”. Journal of antibiotics 72.10 (2019): 729-735.
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Daten bereitgestellt von Europe PubMed Central.
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