Fluorogenic Diversification of Unprotected Bromotryptophan by Aqueous Mizoroki-Heck Cross-Coupling

Gruß H, Belu C, Bernhard LM, Merschel A, Sewald N (2019)
CHEMISTRY-A EUROPEAN JOURNAL 25(23): 5880-5883.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor*in
Gruß, HendrikUniBi; Belu, Clara; Bernhard, Laura M.; Merschel, Arne; Sewald, NorbertUniBi
Abstract / Bemerkung
Fluorescent styryl-tryptophans have been synthesized by a Mizoroki-Heck cross-coupling from unprotected bromotryptophan in aqueous medium showing promising spectrophotometric properties for possible application in fluorescence labelling of biomolecules. Moreover, this strategy permits a modular combination of biocatalytic halogenation by using immobilized FAD-dependent tryptophan halogenases and Pd-mediated chemocatalysis in a multistep one-pot process.
Stichworte
aqueous medium; chemoenzymatic process; fluorescence; halotryptophan; Mizoroki-Heck cross-coupling
Erscheinungsjahr
2019
Zeitschriftentitel
CHEMISTRY-A EUROPEAN JOURNAL
Band
25
Ausgabe
23
Seite(n)
5880-5883
ISSN
0947-6539
eISSN
1521-3765
Page URI
https://pub.uni-bielefeld.de/record/2935878

Zitieren

Gruß H, Belu C, Bernhard LM, Merschel A, Sewald N. Fluorogenic Diversification of Unprotected Bromotryptophan by Aqueous Mizoroki-Heck Cross-Coupling. CHEMISTRY-A EUROPEAN JOURNAL. 2019;25(23):5880-5883.
Gruß, H., Belu, C., Bernhard, L. M., Merschel, A., & Sewald, N. (2019). Fluorogenic Diversification of Unprotected Bromotryptophan by Aqueous Mizoroki-Heck Cross-Coupling. CHEMISTRY-A EUROPEAN JOURNAL, 25(23), 5880-5883. doi:10.1002/chem.201900437
Gruß, H., Belu, C., Bernhard, L. M., Merschel, A., and Sewald, N. (2019). Fluorogenic Diversification of Unprotected Bromotryptophan by Aqueous Mizoroki-Heck Cross-Coupling. CHEMISTRY-A EUROPEAN JOURNAL 25, 5880-5883.
Gruß, H., et al., 2019. Fluorogenic Diversification of Unprotected Bromotryptophan by Aqueous Mizoroki-Heck Cross-Coupling. CHEMISTRY-A EUROPEAN JOURNAL, 25(23), p 5880-5883.
H. Gruß, et al., “Fluorogenic Diversification of Unprotected Bromotryptophan by Aqueous Mizoroki-Heck Cross-Coupling”, CHEMISTRY-A EUROPEAN JOURNAL, vol. 25, 2019, pp. 5880-5883.
Gruß, H., Belu, C., Bernhard, L.M., Merschel, A., Sewald, N.: Fluorogenic Diversification of Unprotected Bromotryptophan by Aqueous Mizoroki-Heck Cross-Coupling. CHEMISTRY-A EUROPEAN JOURNAL. 25, 5880-5883 (2019).
Gruß, Hendrik, Belu, Clara, Bernhard, Laura M., Merschel, Arne, and Sewald, Norbert. “Fluorogenic Diversification of Unprotected Bromotryptophan by Aqueous Mizoroki-Heck Cross-Coupling”. CHEMISTRY-A EUROPEAN JOURNAL 25.23 (2019): 5880-5883.
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