PUB - Publikationen an der Universität Bielefeld

Controlling the false discovery rate: A practical and powerful approach to multiple testing
Benjamini Y, Hochberg Y., 1995

The control of the false discovery rate in multiple testing under dependency
Benjamini Y, Yekutieli D., 2001

Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications.
Berry CE, Hare JM., J. Physiol. (Lond.) 555(Pt 3), 2003
PMID: 14694147

1-Methylxanthine derived from caffeine as a pharmacodynamic probe of oxypurinol effect.
Birkett DJ, Miners JO, Valente L, Lillywhite KJ, Day RO., Br J Clin Pharmacol 43(2), 1997
PMID: 9131954

Coffee, tea, and caffeine consumption and serum uric acid level: the third national health and nutrition examination survey.
Choi HK, Curhan G., Arthritis Rheum. 57(5), 2007
PMID: 17530681

Protein damage and degradation by oxygen radicals. II. Modification of amino acids.
Davies KJ, Delsignore ME, Lin SW., J. Biol. Chem. 262(20), 1987
PMID: 3036876

SLC2A9 influences uric acid concentrations with pronounced sex-specific effects.
Doring A, Gieger C, Mehta D, Gohlke H, Prokisch H, Coassin S, Fischer G, Henke K, Klopp N, Kronenberg F, Paulweber B, Pfeufer A, Rosskopf D, Volzke H, Illig T, Meitinger T, Wichmann HE, Meisinger C., Nat. Genet. 40(4), 2008
PMID: 18327256

Integrated, nontargeted ultrahigh performance liquid chromatography/electrospray ionization tandem mass spectrometry platform for the identification and relative quantification of the small-molecule complement of biological systems.
Evans AM, DeHaven CD, Barrett T, Mitchell M, Milgram E., Anal. Chem. 81(16), 2009
PMID: 19624122

Association between serum homocysteine and markers of impaired kidney function in adults in the United States.
Francis ME, Eggers PW, Hostetter TH, Briggs JP., Kidney Int. 66(1), 2004
PMID: 15200438

Xanthine oxidase inhibition by allopurinol affects the reliability of urinary caffeine metabolic ratios as markers for N-acetyltransferase 2 and CYP1A2 activities.
Fuchs P, Haefeli WE, Ledermann HR, Wenk M., Eur. J. Clin. Pharmacol. 54(11), 1999
PMID: 10027663

Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress.
George J, Struthers AD., Vasc Health Risk Manag 5(1), 2009
PMID: 19436671

Hormonal aspects of human gout--excretion of adrenal hormone derivatives in gouty patients.
Gregolini L, Ferrari S, Marcolongo R, Aleo MF, Marinello E, Bianchi E., Clin. Chim. Acta 130(3), 1983
PMID: 6223725

Human liver xanthine oxidase: nature and extent of individual variation.
Guerciolini R, Szumlanski C, Weinshilboum RM., Clin. Pharmacol. Ther. 50(6), 1991
PMID: 1752110

Uric acid: A new look at an old risk marker for cardiovascular disease, metabolic syndrome, and type 2 diabetes mellitus: The urate redox shuttle.
Hayden MR, Tyagi SC., Nutr Metab (Lond) 1(1), 2004
PMID: 15507132

Studies on the oxidative half-reaction of xanthine oxidase.
Hille R, Massey V., J. Biol. Chem. 256(17), 1981
PMID: 6894924

KORA--a research platform for population based health research.
Holle R, Happich M, Lowel H, Wichmann HE; MONICA/KORA Study Group., Gesundheitswesen 67 Suppl 1(), 2005
PMID: 16032513

Homocysteine level and coronary heart disease incidence: a systematic review and meta-analysis.
Humphrey LL, Fu R, Rogers K, Freeman M, Helfand M., Mayo Clin. Proc. 83(11), 2008
PMID: 18990318

Urate transport via human PAH transporter hOAT1 and its gene structure.
Ichida K, Hosoyamada M, Kimura H, Takeda M, Utsunomiya Y, Hosoya T, Endou H., Kidney Int. 63(1), 2003
PMID: 12472777

Uric acid as a cardiometabolic risk factor: to be or not to be.
Kanbay M, Afsar B, Covic A., Contrib Nephrol 171(), 2011
PMID: 21625091

Uric acid, type 2 diabetes, and cardiovascular diseases: fueling the common soil hypothesis?
Koenig W, Meisinger C., Clin. Chem. 54(2), 2008
PMID: 18223129

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.
Kolz M, Johnson T, Sanna S, Teumer A, Vitart V, Perola M, Mangino M, Albrecht E, Wallace C, Farrall M, Johansson A, Nyholt DR, Aulchenko Y, Beckmann JS, Bergmann S, Bochud M, Brown M, Campbell H; EUROSPAN Consortium, Connell J, Dominiczak A, Homuth G, Lamina C, McCarthy MI; ENGAGE Consortium, Meitinger T, Mooser V, Munroe P, Nauck M, Peden J, Prokisch H, Salo P, Salomaa V, Samani NJ, Schlessinger D, Uda M, Volker U, Waeber G, Waterworth D, Wang-Sattler R, Wright AF, Adamski J, Whitfield JB, Gyllensten U, Wilson JF, Rudan I, Pramstaller P, Watkins H; PROCARDIS Consortium, Doering A, Wichmann HE; KORA Study, Spector TD, Peltonen L, Volzke H, Nagaraja R, Vollenweider P, Caulfield M; WTCCC, Illig T, Gieger C., PLoS Genet. 5(6), 2009
PMID: 19503597

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
Kottgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, Pistis G, Ruggiero D, O'Seaghdha CM, Haller T, Yang Q, Tanaka T, Johnson AD, Kutalik Z, Smith AV, Shi J, Struchalin M, Middelberg RP, Brown MJ, Gaffo AL, Pirastu N, Li G, Hayward C, Zemunik T, Huffman J, Yengo L, Zhao JH, Demirkan A, Feitosa MF, Liu X, Malerba G, Lopez LM, van der Harst P, Li X, Kleber ME, Hicks AA, Nolte IM, Johansson A, Murgia F, Wild SH, Bakker SJ, Peden JF, Dehghan A, Steri M, Tenesa A, Lagou V, Salo P, Mangino M, Rose LM, Lehtimaki T, Woodward OM, Okada Y, Tin A, Muller C, Oldmeadow C, Putku M, Czamara D, Kraft P, Frogheri L, Thun GA, Grotevendt A, Gislason GK, Harris TB, Launer LJ, McArdle P, Shuldiner AR, Boerwinkle E, Coresh J, Schmidt H, Schallert M, Martin NG, Montgomery GW, Kubo M, Nakamura Y, Tanaka T, Munroe PB, Samani NJ, Jacobs DR Jr, Liu K, D'Adamo P, Ulivi S, Rotter JI, Psaty BM, Vollenweider P, Waeber G, Campbell S, Devuyst O, Navarro P, Kolcic I, Hastie N, Balkau B, Froguel P, Esko T, Salumets A, Khaw KT, Langenberg C, Wareham NJ, Isaacs A, Kraja A, Zhang Q, Wild PS, Scott RJ, Holliday EG, Org E, Viigimaa M, Bandinelli S, Metter JE, Lupo A, Trabetti E, Sorice R, Doring A, Lattka E, Strauch K, Theis F, Waldenberger M, Wichmann HE, Davies G, Gow AJ, Bruinenberg M; LifeLines Cohort Study, Stolk RP, Kooner JS, Zhang W, Winkelmann BR, Boehm BO, Lucae S, Penninx BW, Smit JH, Curhan G, Mudgal P, Plenge RM, Portas L, Persico I, Kirin M, Wilson JF, Mateo Leach I, van Gilst WH, Goel A, Ongen H, Hofman A, Rivadeneira F, Uitterlinden AG, Imboden M, von Eckardstein A, Cucca F, Nagaraja R, Piras MG, Nauck M, Schurmann C, Budde K, Ernst F, Farrington SM, Theodoratou E, Prokopenko I, Stumvoll M, Jula A, Perola M, Salomaa V, Shin SY, Spector TD, Sala C, Ridker PM, Kahonen M, Viikari J, Hengstenberg C, Nelson CP; CARDIoGRAM Consortium; DIAGRAM Consortium; ICBP Consortium; MAGIC Consortium, Meschia JF, Nalls MA, Sharma P, Singleton AB, Kamatani N, Zeller T, Burnier M, Attia J, Laan M, Klopp N, Hillege HL, Kloiber S, Choi H, Pirastu M, Tore S, Probst-Hensch NM, Volzke H, Gudnason V, Parsa A, Schmidt R, Whitfield JB, Fornage M, Gasparini P, Siscovick DS, Polasek O, Campbell H, Rudan I, Bouatia-Naji N, Metspalu A, Loos RJ, van Duijn CM, Borecki IB, Ferrucci L, Gambaro G, Deary IJ, Wolffenbuttel BH, Chambers JC, Marz W, Pramstaller PP, Snieder H, Gyllensten U, Wright AF, Navis G, Watkins H, Witteman JC, Sanna S, Schipf S, Dunlop MG, Tonjes A, Ripatti S, Soranzo N, Toniolo D, Chasman DI, Raitakari O, Kao WH, Ciullo M, Fox CS, Caulfield M, Bochud M, Gieger C., Nat. Genet. 45(2), 2012
PMID: 23263486

Gaussian graphical modeling reconstructs pathway reactions from high-throughput metabolomics data.
Krumsiek J, Suhre K, Illig T, Adamski J, Theis FJ., BMC Syst Biol 5(), 2011
PMID: 21281499

Mining the unknown: a systems approach to metabolite identification combining genetic and metabolic information.
Krumsiek J, Suhre K, Evans AM, Mitchell MW, Mohney RP, Milburn MV, Wagele B, Romisch-Margl W, Illig T, Adamski J, Gieger C, Theis FJ, Kastenmuller G., PLoS Genet. 8(10), 2012
PMID: 23093944

A comparison of chronic aspartame exposure to aspirin on inflammation, hyperalgesia and open field activity following carrageenan-induced monoarthritis.
LaBuda CJ, Fuchs PN., Life Sci. 69(4), 2001
PMID: 11459435

AUTHOR UNKNOWN, 0

The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts.
Li S, Sanna S, Maschio A, Busonero F, Usala G, Mulas A, Lai S, Dei M, Orru M, Albai G, Bandinelli S, Schlessinger D, Lakatta E, Scuteri A, Najjar SS, Guralnik J, Naitza S, Crisponi L, Cao A, Abecasis G, Ferrucci L, Uda M, Chen WM, Nagaraja R., PLoS Genet. 3(11), 2007
PMID: 17997608

Homocystein and carotid atherosclerosis in chronic renal failure.
Lubomirova M, Tzoncheva A, Petrova J, Kiperova B., Hippokratia 11(4), 2007
PMID: 19582196

Plasma total homocysteine in healthy subjects: sex-specific relation with biological traits.
Lussier-Cacan S, Xhignesse M, Piolot A, Selhub J, Davignon J, Genest J Jr., Am. J. Clin. Nutr. 64(4), 1996
PMID: 8839504

Metabolomics in the fields of oncology: a review of recent research.
Ma Y, Zhang P, Yang Y, Wang F, Qin H., Mol. Biol. Rep. 39(7), 2012
PMID: 22350159

Role of blood pressure, uric acid, and hemorheological parameters on plasma homocyst(e)ine concentration.
Malinow MR, Levenson J, Giral P, Nieto FJ, Razavian M, Segond P, Simon A., Atherosclerosis 114(2), 1995
PMID: 7605386

Dietary aspartyl-phenylalanine-1-methyl ester delays osteoarthritis and prevents associated bone loss in STR/ORT mice.
Manion CV, Hochgeschwender U, Edmundson AB, Hugli TE, Gabaglia CR., Rheumatology (Oxford) 50(7), 2011
PMID: 21372000

Discovery of sexual dimorphisms in metabolic and genetic biomarkers.
Mittelstrass K, Ried JS, Yu Z, Krumsiek J, Gieger C, Prehn C, Roemisch-Margl W, Polonikov A, Peters A, Theis FJ, Meitinger T, Kronenberg F, Weidinger S, Wichmann HE, Suhre K, Wang-Sattler R, Adamski J, Illig T., PLoS Genet. 7(8), 2011
PMID: 21852955

Clinical practice. Gout.
Neogi T., N. Engl. J. Med. 364(5), 2011
PMID: 21288096

Tryptophan-containing milk protein-derived dipeptides inhibit xanthine oxidase.
Nongonierma AB, Fitzgerald RJ., Peptides 37(2), 2012
PMID: 22910190

Xanthine dehydrogenase and xanthine oxidase activity and gene expression in renal epithelial cells. Cytokine and steroid regulation
Pfeffer KD, Huecksteadt TP, Hoidal JR., 1994

Experimental evaluation of antipyretic and analgesic activity of aspartame.
Pradhan S, Shah UH, Mathur A, Sharma S., Indian J Pharmacol 43(1), 2011
PMID: 21455435

Interference of rheumatoid factor activity by aspartame, a dipeptide methyl ester.
Ramsland PA, Movafagh BF, Reichlin M, Edmundson AB., J. Mol. Recognit. 12(4), 1999
PMID: 10440996

Dehydroepiandrosterone (3 -hydroxy-5-androsten-17-one) metabolism in gout.
Sparagana M, Phillips G., Steroids 19(4), 1972
PMID: 4260438

Human metabolic individuality in biomedical and pharmaceutical research.
Suhre K, Shin SY, Petersen AK, Mohney RP, Meredith D, Wagele B, Altmaier E; CARDIoGRAM, Deloukas P, Erdmann J, Grundberg E, Hammond CJ, de Angelis MH, Kastenmuller G, Kottgen A, Kronenberg F, Mangino M, Meisinger C, Meitinger T, Mewes HW, Milburn MV, Prehn C, Raffler J, Ried JS, Romisch-Margl W, Samani NJ, Small KS, Wichmann HE, Zhai G, Illig T, Spector TD, Adamski J, Soranzo N, Gieger C, Kathiresan S, Reilly MP, Samani NJ, Schunkert H, Erdmann J, Assimes TL, Boerwinkle E, Erdmann J, Hall A, Hengstenberg C, Kathiresan S, Konig IR, Laaksonen R, McPherson R, Reilly MP, Samani NJ, Schunkert H, Thompson JR, Thorsteinsdottir U, Ziegler A, Konig IR, Thompson JR, Absher D, Chen L, Cupples LA, Halperin E, Li M, Musunuru K, Preuss M, Schillert A, Thorleifsson G, Voight BF, Wells GA, Absher D, Assimes TL, Deloukas P, Erdmann J, Holm H, Kathiresan S, Konig IR, McPherson R, Reilly MP, Roberts R, Samani NJ, Schunkert H, Stewart AF, Fortmann S, Go A, Hlatky M, Iribarren C, Knowles J, Myers R, Quertermous T, Sidney S, Risch N, Tang H, Blankenberg S, Zeller T, Schillert A, Wild P, Ziegler A, Schnabel R, Sinning C, Lackner K, Tiret L, Nicaud V, Cambien F, Bickel C, Rupprecht HJ, Perret C, Proust C, Munzel T, Barbalic M, Bis J, Boerwinkle E, Chen IY, Cupples LA, Dehghan A, Demissie-Banjaw S, Folsom A, Glazer N, Gudnason V, Harris T, Heckbert S, Levy D, Lumley T, Marciante K, Morrison A, O'Donnell CJ, Psaty BM, Rice K, Rotter JI, Siscovick DS, Smith N, Smith A, Taylor KD, van Duijn C, Volcik K, Whitteman J, Ramachandran V, Hofman A, Uitterlinden A, Gretarsdottir S, Gulcher JR, Holm H, Kong A, Stefansson K, Thorgeirsson G, Andersen K, Thorleifsson G, Thorsteinsdottir U, Erdmann J, Fischer M, Grosshennig A, Hengstenberg C, Konig IR, Lieb W, Linsel-Nitschke P, Preuss M, Stark K, Schreiber S, Wichmann HE, Ziegler A, Schunkert H, Aherrahrou Z, Bruse P, Doering A, Erdmann J, Hengstenberg C, Illig T, Klopp N, Konig IR, Linsel-Nitschke P, Loley C, Medack A, Meisinger C, Meitinger T, Nahrstedt J, Peters A, Preuss M, Stark K, Wagner AK, Wichmann HE, Willenborg C, Ziegler A, Schunkert H, Bohm BO, Dobnig H, Grammer TB, Halperin E, Hoffmann MM, Kleber M, Laaksonen R, Marz W, Meinitzer A, Winkelmann BR, Pilz S, Renner W, Scharnagl H, Stojakovic T, Tomaschitz A, Winkler K, Voight BF, Musunuru K, Guiducci C, Burtt N, Gabriel SB, Siscovick DS, O'Donnell CJ, Elosua R, Peltonen L, Salomaa V, Schwartz SM, Melander O, Altshuler D, Kathiresan S, Stewart AF, Chen L, Dandona S, Wells GA, Jarinova O, McPherson R, Roberts R, Reilly MP, Li M, Qu L, Wilensky R, Matthai W, Hakonarson HH, Devaney J, Burnett MS, Pichard AD, Kent KM, Satler L, Lindsay JM, Waksman R, Knouff CW, Waterworth DM, Walker MC, Mooser V, Epstein SE, Rader DJ, Samani NJ, Thompson JR, Braund PS, Nelson CP, Wright BJ, Balmforth AJ, Ball SG, Hall AS., Nature 477(7362), 2011
PMID: 21886157

AUTHOR UNKNOWN, 0

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout.
Vitart V, Rudan I, Hayward C, Gray NK, Floyd J, Palmer CN, Knott SA, Kolcic I, Polasek O, Graessler J, Wilson JF, Marinaki A, Riches PL, Shu X, Janicijevic B, Smolej-Narancic N, Gorgoni B, Morgan J, Campbell S, Biloglav Z, Barac-Lauc L, Pericic M, Klaric IM, Zgaga L, Skaric-Juric T, Wild SH, Richardson WA, Hohenstein P, Kimber CH, Tenesa A, Donnelly LA, Fairbanks LD, Aringer M, McKeigue PM, Ralston SH, Morris AD, Rudan P, Hastie ND, Campbell H, Wright AF., Nat. Genet. 40(4), 2008
PMID: 18327257

Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.
Wallace C, Newhouse SJ, Braund P, Zhang F, Tobin M, Falchi M, Ahmadi K, Dobson RJ, Marcano AC, Hajat C, Burton P, Deloukas P, Brown M, Connell JM, Dominiczak A, Lathrop GM, Webster J, Farrall M, Spector T, Samani NJ, Caulfield MJ, Munroe PB., Am. J. Hum. Genet. 82(1), 2008
PMID: 18179892

KORA-gen--resource for population genetics, controls and a broad spectrum of disease phenotypes.
Wichmann HE, Gieger C, Illig T; MONICA/KORA Study Group., Gesundheitswesen 67 Suppl 1(), 2005
PMID: 16032514

Remote communication through solute carriers and ATP binding cassette drug transporter pathways: an update on the remote sensing and signaling hypothesis.
Wu W, Dnyanmote AV, Nigam SK., Mol. Pharmacol. 79(5), 2011
PMID: 21325265

Interrelationship between methionine and cystine of early Peking ducklings.
Xie M, Hou SS, Huang W, Zhao L, Yu JY, Li WY, Wu YY., Poult. Sci. 83(10), 2004
PMID: 15510556

Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.
Yang Q, Kottgen A, Dehghan A, Smith AV, Glazer NL, Chen MH, Chasman DI, Aspelund T, Eiriksdottir G, Harris TB, Launer L, Nalls M, Hernandez D, Arking DE, Boerwinkle E, Grove ML, Li M, Linda Kao WH, Chonchol M, Haritunians T, Li G, Lumley T, Psaty BM, Shlipak M, Hwang SJ, Larson MG, O'Donnell CJ, Upadhyay A, van Duijn CM, Hofman A, Rivadeneira F, Stricker B, Uitterlinden AG, Pare G, Parker AN, Ridker PM, Siscovick DS, Gudnason V, Witteman JC, Fox CS, Coresh J., Circ Cardiovasc Genet 3(6), 2010
PMID: 20884846